PL2931922T3 - Personalizowane biomarkery nowotworu - Google Patents

Personalizowane biomarkery nowotworu

Info

Publication number
PL2931922T3
PL2931922T3 PL13863107T PL13863107T PL2931922T3 PL 2931922 T3 PL2931922 T3 PL 2931922T3 PL 13863107 T PL13863107 T PL 13863107T PL 13863107 T PL13863107 T PL 13863107T PL 2931922 T3 PL2931922 T3 PL 2931922T3
Authority
PL
Poland
Prior art keywords
cancer
personalized biomarkers
biomarkers
personalized
Prior art date
Application number
PL13863107T
Other languages
English (en)
Inventor
Ekkehard Schütz
Julia Beck
Howard Urnovitz
Original Assignee
Chronix Biomedical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chronix Biomedical filed Critical Chronix Biomedical
Publication of PL2931922T3 publication Critical patent/PL2931922T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL13863107T 2012-12-14 2013-12-13 Personalizowane biomarkery nowotworu PL2931922T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261737626P 2012-12-14 2012-12-14
PCT/US2013/075015 WO2014093825A1 (en) 2012-12-14 2013-12-13 Personalized biomarkers for cancer
EP13863107.2A EP2931922B1 (en) 2012-12-14 2013-12-13 Personalized biomarkers for cancer

Publications (1)

Publication Number Publication Date
PL2931922T3 true PL2931922T3 (pl) 2019-04-30

Family

ID=50934991

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13863107T PL2931922T3 (pl) 2012-12-14 2013-12-13 Personalizowane biomarkery nowotworu

Country Status (5)

Country Link
US (1) US9909186B2 (pl)
EP (1) EP2931922B1 (pl)
ES (1) ES2703764T3 (pl)
PL (1) PL2931922T3 (pl)
WO (1) WO2014093825A1 (pl)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3561072A1 (en) 2012-12-10 2019-10-30 Resolution Bioscience, Inc. Methods for targeted genomic analysis
WO2014113204A1 (en) 2013-01-17 2014-07-24 Personalis, Inc. Methods and systems for genetic analysis
EP3965111B8 (en) 2013-08-30 2025-06-11 Personalis, Inc. Methods for genomic analysis
GB2535066A (en) 2013-10-03 2016-08-10 Personalis Inc Methods for analyzing genotypes
US20160053301A1 (en) 2014-08-22 2016-02-25 Clearfork Bioscience, Inc. Methods for quantitative genetic analysis of cell free dna
JP7441584B6 (ja) * 2014-08-22 2024-03-15 レゾリューション バイオサイエンス, インコーポレイテッド 無細胞DNA(cfDNA)の定量的遺伝子解析のための方法
US10125399B2 (en) 2014-10-30 2018-11-13 Personalis, Inc. Methods for using mosaicism in nucleic acids sampled distal to their origin
US20180305757A1 (en) * 2015-10-16 2018-10-25 The Regents Of The University Of California Repetitive Element (RE)-based Genome Analysis and Dynamic Genetics Surveillance Systems
EP3374525B1 (en) 2015-11-11 2021-01-20 Resolution Bioscience, Inc. High efficiency construction of dna libraries
US11299783B2 (en) 2016-05-27 2022-04-12 Personalis, Inc. Methods and systems for genetic analysis
IL264971B2 (en) 2016-08-25 2024-10-01 Resolution Bioscience Inc Methods for identifying changes in a genomic copy in DNA samples
EP3541950A4 (en) * 2016-11-16 2020-06-03 Progenity, Inc. MULTIMODAL ASSAY FOR THE DETECTION OF NUCLEIC ACID ABERRATIONS
US10801064B2 (en) 2018-05-31 2020-10-13 Personalis, Inc. Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
US11814750B2 (en) 2018-05-31 2023-11-14 Personalis, Inc. Compositions, methods and systems for processing or analyzing multi-species nucleic acid samples
WO2020168239A1 (en) * 2019-02-15 2020-08-20 Takara Bio Usa, Inc. Methods of preparing and analyzing nucleic acid libraries
CN109825583B (zh) * 2019-03-01 2021-08-17 清华大学 人重复元件dna甲基化作为肝癌早期诊断的标记物及其应用
JP7470787B2 (ja) 2019-11-05 2024-04-18 パーソナリス,インコーポレイティド 単一試料からの腫瘍純度の推定
CA3186014A1 (en) * 2020-08-24 2022-03-03 Gerassimos Makrigiorgos Enhanced sequencing following random dna ligation and repeat element amplification
WO2023059654A1 (en) 2021-10-05 2023-04-13 Personalis, Inc. Customized assays for personalized cancer monitoring
WO2025059176A1 (en) * 2023-09-15 2025-03-20 The Johns Hopkins University Assessing and treating cancer

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5955589A (en) 1991-12-24 1999-09-21 Isis Pharmaceuticals Inc. Gapped 2' modified oligonucleotides
YU187991A (sh) 1990-12-11 1994-09-09 Hoechst Aktiengesellschaft 3-(2)-amino-ali tiol-modifikovani, s fluorescentnom bojom vezani nukleozidi, nukleotidi i oligonukleotidi, postupak za njihovo dobijanje i njihova upotreba
US5652099A (en) 1992-02-12 1997-07-29 Conrad; Michael J. Probes comprising fluorescent nucleosides and uses thereof
US5446137B1 (en) 1993-12-09 1998-10-06 Behringwerke Ag Oligonucleotides containing 4'-substituted nucleotides
DE4415370A1 (de) 1994-05-02 1995-11-09 Hoechst Ag Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung
DE4438918A1 (de) 1994-11-04 1996-05-09 Hoechst Ag Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung
US5773649A (en) * 1996-06-10 1998-06-30 Centre De Recherche De L'hopital Sainte-Justine DNA markers to detect cancer cells expressing a mutator phenotype and method of diagnosis of cancer cells
EP0960210A4 (en) * 1996-10-04 2004-06-09 Chronix Biomedical Diagnostic detection of nucleic acids
DE69827060T2 (de) 1997-03-20 2005-03-24 F. Hoffmann-La Roche Ag Modifizierte Primer
USH2191H1 (en) 2000-10-24 2007-06-05 Snp Consortium Identification and mapping of single nucleotide polymorphisms in the human genome
WO2007111937A1 (en) * 2006-03-23 2007-10-04 Applera Corporation Directed enrichment of genomic dna for high-throughput sequencing
US8986958B2 (en) * 2009-03-30 2015-03-24 Life Technologies Corporation Methods for generating target specific probes for solution based capture
CN102409048B (zh) * 2010-09-21 2013-10-23 深圳华大基因科技服务有限公司 一种基于高通量测序的dna标签文库构建方法
CA2830329A1 (en) * 2011-03-18 2012-09-27 Baylor Research Institute Line-1 hypomethylation as a biomarker for early-onset colorectal cancer
GB201106254D0 (en) * 2011-04-13 2011-05-25 Frisen Jonas Method and product
JP2015534806A (ja) * 2012-10-19 2015-12-07 シーケンタ・インコーポレイテッド 末梢血試料によるびまん性大細胞型b細胞性リンパ腫のモニタリング関連出願の相互参照本出願は、2012年10月19日出願の米国特許仮出願第61/716,270号の利益を主張するものであり、当該出願は参照により本明細書にその全体が組み込まれる。

Also Published As

Publication number Publication date
US9909186B2 (en) 2018-03-06
EP2931922B1 (en) 2018-10-17
ES2703764T3 (es) 2019-03-12
US20160053328A1 (en) 2016-02-25
EP2931922A4 (en) 2016-07-27
EP2931922A1 (en) 2015-10-21
WO2014093825A1 (en) 2014-06-19

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