BG61320B2 - N-оксиди на алфа,алфа-диарил-4-арил-4-хидрокси-1- пиперидинбутанамид - Google Patents

N-оксиди на алфа,алфа-диарил-4-арил-4-хидрокси-1- пиперидинбутанамид Download PDF

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Publication number
BG61320B2
BG61320B2 BG97952A BG9795293A BG61320B2 BG 61320 B2 BG61320 B2 BG 61320B2 BG 97952 A BG97952 A BG 97952A BG 9795293 A BG9795293 A BG 9795293A BG 61320 B2 BG61320 B2 BG 61320B2
Authority
BG
Bulgaria
Prior art keywords
compound
compounds
phenyl
hydroxy
formula
Prior art date
Application number
BG97952A
Other languages
Bulgarian (bg)
English (en)
Inventor
Wals Lourens Van
Ludwig Cooymans
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of BG61320B2 publication Critical patent/BG61320B2/bg

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Compositions Of Oxide Ceramics (AREA)
BG97952A 1985-10-11 1993-07-15 N-оксиди на алфа,алфа-диарил-4-арил-4-хидрокси-1- пиперидинбутанамид BG61320B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78656685A 1985-10-11 1985-10-11

Publications (1)

Publication Number Publication Date
BG61320B2 true BG61320B2 (bg) 1997-05-30

Family

ID=25138953

Family Applications (1)

Application Number Title Priority Date Filing Date
BG97952A BG61320B2 (bg) 1985-10-11 1993-07-15 N-оксиди на алфа,алфа-диарил-4-арил-4-хидрокси-1- пиперидинбутанамид

Country Status (33)

Country Link
EP (1) EP0219898B1 (pt)
JP (1) JPS6287569A (pt)
KR (1) KR940001772B1 (pt)
CN (1) CN1015453B (pt)
AT (1) ATE53022T1 (pt)
AU (1) AU583429B2 (pt)
BG (1) BG61320B2 (pt)
CA (1) CA1332236C (pt)
CY (1) CY1603A (pt)
DE (1) DE3671442D1 (pt)
DK (1) DK173954B1 (pt)
DZ (1) DZ997A1 (pt)
EG (1) EG18126A (pt)
ES (1) ES2002001A6 (pt)
FI (1) FI83642C (pt)
GR (1) GR862493B (pt)
HK (1) HK52491A (pt)
HU (1) HU196180B (pt)
IE (1) IE59519B1 (pt)
IL (1) IL80268A (pt)
LT (1) LT2086B (pt)
LV (2) LV5042A3 (pt)
NL (1) NL950025I2 (pt)
NO (2) NO168640C (pt)
NZ (1) NZ217818A (pt)
PH (1) PH22510A (pt)
PT (1) PT83506B (pt)
SG (1) SG46291G (pt)
SU (1) SU1443798A3 (pt)
TN (1) TNSN86138A1 (pt)
ZA (1) ZA867713B (pt)
ZM (1) ZM9486A1 (pt)
ZW (1) ZW20386A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002223A1 (en) * 1990-08-09 1992-02-20 The Procter & Gamble Company Process for formulating a solid oral dosage form of loperamide compounds
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
WO1997024325A1 (en) * 1995-12-28 1997-07-10 Takeda Chemical Industries, Ltd. DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS
CN1291984A (zh) * 1998-03-06 2001-04-18 詹森药业有限公司 甘氨酸传输抑制剂
KR101315751B1 (ko) * 2011-05-30 2013-10-10 주식회사 엔지켐생명과학 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714159A (en) * 1971-03-30 1973-01-30 Janssen Pharmaceutica Nv 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
US4002618A (en) * 1976-02-23 1977-01-11 G. D. Searle & Co. 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles

Also Published As

Publication number Publication date
NL950025I1 (pt) 1996-01-02
FI83642B (fi) 1991-04-30
LV5042A3 (lv) 1993-06-10
CA1332236C (en) 1994-10-04
ATE53022T1 (de) 1990-06-15
KR870003986A (ko) 1987-05-06
EP0219898A1 (en) 1987-04-29
LV5767B4 (lv) 1997-06-20
IE862677L (en) 1987-04-11
NZ217818A (en) 1989-03-29
CN1015453B (zh) 1992-02-12
NO864045L (no) 1987-04-13
FI83642C (fi) 1991-08-12
NO168640C (no) 1992-03-18
TNSN86138A1 (fr) 1990-01-01
DE3671442D1 (de) 1990-06-28
HK52491A (en) 1991-07-19
SG46291G (en) 1991-07-26
CY1603A (en) 1992-04-03
PH22510A (en) 1988-09-12
NL950025I2 (nl) 1997-03-03
NO168640B (no) 1991-12-09
DK486886A (da) 1987-04-12
ES2002001A6 (es) 1988-07-01
JPS6287569A (ja) 1987-04-22
AU583429B2 (en) 1989-04-27
LV5767A4 (lv) 1996-12-20
PT83506B (pt) 1989-02-28
GR862493B (en) 1987-02-03
HU196180B (en) 1988-10-28
DZ997A1 (fr) 2004-09-13
AU6381586A (en) 1987-04-16
PT83506A (en) 1986-11-01
LT2086B (lt) 1993-07-15
FI864099A0 (fi) 1986-10-10
HUT42444A (en) 1987-07-28
NO1996010I1 (no) 1996-08-06
CN86106848A (zh) 1987-04-08
DK173954B1 (da) 2002-03-04
FI864099A (fi) 1987-04-12
IE59519B1 (en) 1994-03-09
ZA867713B (en) 1988-05-25
ZW20386A1 (en) 1988-05-11
JPH0517909B2 (pt) 1993-03-10
EP0219898B1 (en) 1990-05-23
DK486886D0 (da) 1986-10-10
ZM9486A1 (en) 1988-04-29
IL80268A0 (en) 1987-01-30
IL80268A (en) 1991-03-10
SU1443798A3 (ru) 1988-12-07
NO864045D0 (no) 1986-10-10
KR940001772B1 (ko) 1994-03-05
EG18126A (en) 1992-08-30

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