NO168640C - Analogifremgangsmaate for fremstilling av nye alfa, alfa-diaryl-4-aryl-4-hydroksy-1-piperidinbutanamid, n-oksyder - Google Patents

Analogifremgangsmaate for fremstilling av nye alfa, alfa-diaryl-4-aryl-4-hydroksy-1-piperidinbutanamid, n-oksyder

Info

Publication number
NO168640C
NO168640C NO864045A NO864045A NO168640C NO 168640 C NO168640 C NO 168640C NO 864045 A NO864045 A NO 864045A NO 864045 A NO864045 A NO 864045A NO 168640 C NO168640 C NO 168640C
Authority
NO
Norway
Prior art keywords
alfa
diaryl
aryl
hydroxy
6alkyl
Prior art date
Application number
NO864045A
Other languages
English (en)
Norwegian (no)
Other versions
NO864045D0 (no
NO168640B (no
NO864045L (no
Inventor
Lourens Wals
Ludwig Paul Cooymans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO864045D0 publication Critical patent/NO864045D0/no
Publication of NO864045L publication Critical patent/NO864045L/no
Publication of NO168640B publication Critical patent/NO168640B/no
Publication of NO168640C publication Critical patent/NO168640C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Compositions Of Oxide Ceramics (AREA)
NO864045A 1985-10-11 1986-10-10 Analogifremgangsmaate for fremstilling av nye alfa, alfa-diaryl-4-aryl-4-hydroksy-1-piperidinbutanamid, n-oksyder NO168640C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78656685A 1985-10-11 1985-10-11

Publications (4)

Publication Number Publication Date
NO864045D0 NO864045D0 (no) 1986-10-10
NO864045L NO864045L (no) 1987-04-13
NO168640B NO168640B (no) 1991-12-09
NO168640C true NO168640C (no) 1992-03-18

Family

ID=25138953

Family Applications (2)

Application Number Title Priority Date Filing Date
NO864045A NO168640C (no) 1985-10-11 1986-10-10 Analogifremgangsmaate for fremstilling av nye alfa, alfa-diaryl-4-aryl-4-hydroksy-1-piperidinbutanamid, n-oksyder
NO1996010C NO1996010I1 (no) 1985-10-11 1996-08-06 Loperamid-oksyd

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO1996010C NO1996010I1 (no) 1985-10-11 1996-08-06 Loperamid-oksyd

Country Status (33)

Country Link
EP (1) EP0219898B1 (pt)
JP (1) JPS6287569A (pt)
KR (1) KR940001772B1 (pt)
CN (1) CN1015453B (pt)
AT (1) ATE53022T1 (pt)
AU (1) AU583429B2 (pt)
BG (1) BG61320B2 (pt)
CA (1) CA1332236C (pt)
CY (1) CY1603A (pt)
DE (1) DE3671442D1 (pt)
DK (1) DK173954B1 (pt)
DZ (1) DZ997A1 (pt)
EG (1) EG18126A (pt)
ES (1) ES2002001A6 (pt)
FI (1) FI83642C (pt)
GR (1) GR862493B (pt)
HK (1) HK52491A (pt)
HU (1) HU196180B (pt)
IE (1) IE59519B1 (pt)
IL (1) IL80268A (pt)
LT (1) LT2086B (pt)
LV (2) LV5042A3 (pt)
NL (1) NL950025I2 (pt)
NO (2) NO168640C (pt)
NZ (1) NZ217818A (pt)
PH (1) PH22510A (pt)
PT (1) PT83506B (pt)
SG (1) SG46291G (pt)
SU (1) SU1443798A3 (pt)
TN (1) TNSN86138A1 (pt)
ZA (1) ZA867713B (pt)
ZM (1) ZM9486A1 (pt)
ZW (1) ZW20386A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0542879A1 (en) * 1990-08-09 1993-05-26 The Procter & Gamble Company Process for formulating a solid oral dosage form of loperamide compounds
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
WO1997024325A1 (en) * 1995-12-28 1997-07-10 Takeda Chemical Industries, Ltd. DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS
SK13092000A3 (sk) * 1998-03-06 2001-03-12 Janssen Pharmaceutica N. V. Inhibítory prenosu glycínu, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie
KR101315751B1 (ko) * 2011-05-30 2013-10-10 주식회사 엔지켐생명과학 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714159A (en) * 1971-03-30 1973-01-30 Janssen Pharmaceutica Nv 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
US4002618A (en) * 1976-02-23 1977-01-11 G. D. Searle & Co. 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles

Also Published As

Publication number Publication date
DZ997A1 (fr) 2004-09-13
KR870003986A (ko) 1987-05-06
AU6381586A (en) 1987-04-16
NL950025I1 (pt) 1996-01-02
EP0219898B1 (en) 1990-05-23
LV5767A4 (lv) 1996-12-20
JPS6287569A (ja) 1987-04-22
CN86106848A (zh) 1987-04-08
DK486886D0 (da) 1986-10-10
ATE53022T1 (de) 1990-06-15
TNSN86138A1 (fr) 1990-01-01
SU1443798A3 (ru) 1988-12-07
NO1996010I1 (no) 1996-08-06
IL80268A (en) 1991-03-10
AU583429B2 (en) 1989-04-27
NO864045D0 (no) 1986-10-10
CN1015453B (zh) 1992-02-12
LV5767B4 (lv) 1997-06-20
FI864099A (fi) 1987-04-12
EG18126A (en) 1992-08-30
SG46291G (en) 1991-07-26
HUT42444A (en) 1987-07-28
EP0219898A1 (en) 1987-04-29
ES2002001A6 (es) 1988-07-01
DK486886A (da) 1987-04-12
PT83506A (en) 1986-11-01
NO168640B (no) 1991-12-09
FI83642B (fi) 1991-04-30
GR862493B (en) 1987-02-03
PT83506B (pt) 1989-02-28
ZA867713B (en) 1988-05-25
CY1603A (en) 1992-04-03
PH22510A (en) 1988-09-12
ZM9486A1 (en) 1988-04-29
IE59519B1 (en) 1994-03-09
LT2086B (lt) 1993-07-15
ZW20386A1 (en) 1988-05-11
FI83642C (fi) 1991-08-12
DK173954B1 (da) 2002-03-04
NO864045L (no) 1987-04-13
NL950025I2 (nl) 1997-03-03
JPH0517909B2 (pt) 1993-03-10
LV5042A3 (lv) 1993-06-10
DE3671442D1 (de) 1990-06-28
IE862677L (en) 1987-04-11
FI864099A0 (fi) 1986-10-10
HU196180B (en) 1988-10-28
HK52491A (en) 1991-07-19
IL80268A0 (en) 1987-01-30
BG61320B2 (bg) 1997-05-30
NZ217818A (en) 1989-03-29
CA1332236C (en) 1994-10-04
KR940001772B1 (ko) 1994-03-05

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