BG35748A3 - Метод за получаване на 2 4- (2- фуроил)- пиперзин- 1- ил- 4- амино- 6,7- диметоксихиназолин - Google Patents

Метод за получаване на 2 4- (2- фуроил)- пиперзин- 1- ил- 4- амино- 6,7- диметоксихиназолин

Info

Publication number
BG35748A3
BG35748A3 BG057396A BG5739677A BG35748A3 BG 35748 A3 BG35748 A3 BG 35748A3 BG 057396 A BG057396 A BG 057396A BG 5739677 A BG5739677 A BG 5739677A BG 35748 A3 BG35748 A3 BG 35748A3
Authority
BG
Bulgaria
Prior art keywords
dimethoxyquinazoline
furoyl
amino
piperzine
obtaining
Prior art date
Application number
BG057396A
Other languages
Bulgarian (bg)
English (en)
Inventor
Philip Hammen
Original Assignee
Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware filed Critical Pfizer Inc., a corporation organized аnd existing under the laws of the State of Delaware
Publication of BG35748A3 publication Critical patent/BG35748A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BG057396A 1976-06-15 1977-06-03 Метод за получаване на 2 4- (2- фуроил)- пиперзин- 1- ил- 4- амино- 6,7- диметоксихиназолин BG35748A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69620176A 1976-06-15 1976-06-15

Publications (1)

Publication Number Publication Date
BG35748A3 true BG35748A3 (bg) 1984-06-15

Family

ID=24796111

Family Applications (3)

Application Number Title Priority Date Filing Date
BG057396A BG35748A3 (bg) 1976-06-15 1977-06-03 Метод за получаване на 2 4- (2- фуроил)- пиперзин- 1- ил- 4- амино- 6,7- диметоксихиназолин
BG036493A BG35594A3 (bg) 1976-06-15 1977-06-03 Метод за получаване на 2 4-(2-фуроил)- пиразин- 1- ил- 4- амино- 6- 7- диметоксихиназолин
BG057395A BG35747A3 (bg) 1976-06-15 1977-06-03 Метод за получаване на 2- 4-(2- фуроил)-пиперазин- 1- ил- 4- амино- 6,7- диметоксихиназолин

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG036493A BG35594A3 (bg) 1976-06-15 1977-06-03 Метод за получаване на 2 4-(2-фуроил)- пиразин- 1- ил- 4- амино- 6- 7- диметоксихиназолин
BG057395A BG35747A3 (bg) 1976-06-15 1977-06-03 Метод за получаване на 2- 4-(2- фуроил)-пиперазин- 1- ил- 4- амино- 6,7- диметоксихиназолин

Country Status (34)

Country Link
JP (1) JPS52153985A (cs)
AR (1) AR218251A1 (cs)
AT (1) AT356115B (cs)
BE (1) BE855656A (cs)
BG (3) BG35748A3 (cs)
CA (1) CA1068698A (cs)
CH (3) CH638203A5 (cs)
CS (1) CS202069B2 (cs)
DD (1) DD131021A5 (cs)
DE (1) DE2725019A1 (cs)
DK (1) DK146625C (cs)
EG (1) EG12922A (cs)
ES (1) ES459364A1 (cs)
FI (1) FI66853C (cs)
FR (1) FR2355015A1 (cs)
GB (1) GB1548856A (cs)
GR (1) GR72288B (cs)
HK (1) HK31481A (cs)
HU (1) HU177883B (cs)
IE (1) IE45423B1 (cs)
IL (1) IL52167A (cs)
LU (1) LU77530A1 (cs)
MY (1) MY8100270A (cs)
NL (1) NL172543C (cs)
NO (1) NO147838C (cs)
NZ (1) NZ184168A (cs)
PH (1) PH22196A (cs)
PL (3) PL111221B1 (cs)
PT (1) PT66617B (cs)
RO (3) RO73050A (cs)
SE (2) SE435380B (cs)
SU (2) SU1033002A3 (cs)
YU (1) YU40164B (cs)
ZA (1) ZA773014B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346675A1 (de) * 1983-12-23 1985-07-04 Beiersdorf Ag, 2000 Hamburg Substituierte 1-(4-amino-6,7-dialkoxy-chinazolinyl)-4- cyclohexenyl-derivate des piperazins und homopiperazins, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen und zwischenprodukte
AT384218B (de) * 1985-12-04 1987-10-12 Gerot Pharmazeutika Verfahren zur herstellung von neuen chinazolin-derivaten
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
IL112249A (en) 1994-01-25 2001-11-25 Warner Lambert Co Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
US5679683A (en) * 1994-01-25 1997-10-21 Warner-Lambert Company Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
IL112248A0 (en) 1994-01-25 1995-03-30 Warner Lambert Co Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
US5932538A (en) * 1996-02-02 1999-08-03 Nitromed, Inc. Nitrosated and nitrosylated α-adrenergic receptor antagonist compounds, compositions and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3669968A (en) 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines
JPS4966691A (cs) * 1972-10-30 1974-06-27
US3935213A (en) 1973-12-05 1976-01-27 Pfizer Inc. Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives
JPS50126682A (cs) * 1974-03-25 1975-10-04

Also Published As

Publication number Publication date
ES459364A1 (es) 1978-03-16
NZ184168A (en) 1979-08-31
SE7705745L (sv) 1977-12-16
CH638517A5 (en) 1983-09-30
DK146625B (da) 1983-11-21
NL7705939A (nl) 1977-12-19
GR72288B (cs) 1983-10-17
CH638203A5 (en) 1983-09-15
CH638516A5 (en) 1983-09-30
PL111221B1 (en) 1980-08-30
RO77330A (ro) 1981-06-22
SU946402A3 (ru) 1982-07-23
DE2725019A1 (de) 1977-12-22
MY8100270A (en) 1981-12-31
HU177883B (en) 1982-01-28
IL52167A0 (en) 1977-07-31
NL172543C (nl) 1983-09-16
FR2355015B1 (cs) 1981-07-24
GB1548856A (en) 1979-07-18
HK31481A (en) 1981-07-10
JPS52153985A (en) 1977-12-21
NO147838B (no) 1983-03-14
FI771741A7 (cs) 1977-12-16
JPS5543465B2 (cs) 1980-11-06
SE8107554L (sv) 1981-12-16
FR2355015A1 (fr) 1978-01-13
AU2558377A (en) 1978-09-07
FI66853B (fi) 1984-08-31
SE450120B (sv) 1987-06-09
YU132677A (en) 1982-08-31
SU1033002A3 (ru) 1983-07-30
RO77308A (ro) 1981-08-17
SE435380B (sv) 1984-09-24
LU77530A1 (fr) 1979-03-26
CS202069B2 (en) 1980-12-31
IL52167A (en) 1981-01-30
PL198874A1 (pl) 1978-04-10
AT356115B (de) 1980-04-10
BG35747A3 (bg) 1984-06-15
IE45423L (en) 1977-12-15
DD131021A5 (de) 1978-05-24
NO147838C (no) 1983-06-22
CA1068698A (en) 1979-12-25
EG12922A (en) 1980-03-31
PT66617B (en) 1978-10-27
ZA773014B (en) 1978-04-26
PL113012B1 (en) 1980-11-29
NO771919L (no) 1977-12-16
PH22196A (en) 1988-06-28
PT66617A (en) 1977-06-01
DK146625C (da) 1984-06-04
BG35594A3 (bg) 1984-05-15
AR218251A1 (es) 1980-05-30
FI66853C (fi) 1984-12-10
YU40164B (en) 1985-08-31
DK240877A (da) 1977-12-16
IE45423B1 (en) 1982-08-25
PL105558B1 (pl) 1979-10-31
ATA386977A (de) 1979-09-15
NL172543B (nl) 1983-04-18
BE855656A (fr) 1977-12-14
RO73050A (ro) 1981-08-30

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