BE897162A - Cephalosporines a activite antibiotique - Google Patents

Cephalosporines a activite antibiotique Download PDF

Info

Publication number
BE897162A
BE897162A BE0/211080A BE211080A BE897162A BE 897162 A BE897162 A BE 897162A BE 0/211080 A BE0/211080 A BE 0/211080A BE 211080 A BE211080 A BE 211080A BE 897162 A BE897162 A BE 897162A
Authority
BE
Belgium
Prior art keywords
compound
acid
formula
salt
desc
Prior art date
Application number
BE0/211080A
Other languages
English (en)
French (fr)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BE897162A publication Critical patent/BE897162A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE0/211080A 1982-06-30 1983-06-29 Cephalosporines a activite antibiotique BE897162A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8218874 1982-06-30

Publications (1)

Publication Number Publication Date
BE897162A true BE897162A (fr) 1983-12-29

Family

ID=10531380

Family Applications (2)

Application Number Title Priority Date Filing Date
BE0/211080A BE897162A (fr) 1982-06-30 1983-06-29 Cephalosporines a activite antibiotique
BE0/211081A BE897163A (fr) 1982-06-30 1983-06-29 Cephalosporines a activite antibiotique

Family Applications After (1)

Application Number Title Priority Date Filing Date
BE0/211081A BE897163A (fr) 1982-06-30 1983-06-29 Cephalosporines a activite antibiotique

Country Status (19)

Country Link
JP (3) JPS5913786A (cs)
KR (2) KR840005151A (cs)
AU (1) AU1638083A (cs)
BE (2) BE897162A (cs)
DE (1) DE3323450A1 (cs)
DK (1) DK298983A (cs)
ES (2) ES523681A0 (cs)
FI (1) FI832384A7 (cs)
FR (2) FR2529556A1 (cs)
GB (1) GB2123415A (cs)
GR (1) GR77528B (cs)
IT (1) IT1173727B (cs)
LU (1) LU84886A1 (cs)
NL (1) NL8302308A (cs)
NO (1) NO832375L (cs)
PL (2) PL242747A1 (cs)
PT (1) PT76959B (cs)
SE (1) SE8303728D0 (cs)
ZA (3) ZA834759B (cs)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001833A1 (en) * 1990-07-18 1992-02-06 Peter John Mitchell Farley Process and apparatus for the production of paper products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS54157519A (en) * 1978-06-01 1979-12-12 Mitsubishi Gas Chem Co Inc Preparation of dimethylformamide
DE2940407A1 (de) * 1979-10-05 1981-04-09 Cornelius Apparate Gmbh, 4018 Langenfeld Verfahren und vorrichtung zur anreicherung von fluessigkeiten mit gasen

Also Published As

Publication number Publication date
ES8500956A1 (es) 1984-11-01
DK298983A (da) 1983-12-31
SE8303728D0 (sv) 1983-06-29
ES530071A0 (es) 1985-11-01
PT76959B (en) 1986-01-24
PT76959A (en) 1983-07-01
JPS5913786A (ja) 1984-01-24
KR840005151A (ko) 1984-11-03
ZA834759B (en) 1984-08-29
LU84886A1 (fr) 1984-03-07
FI832384L (fi) 1983-12-31
ZA834757B (en) 1984-04-25
BE897163A (fr) 1983-12-29
GR77528B (cs) 1984-09-24
ES523681A0 (es) 1984-11-01
PL249795A1 (en) 1985-06-04
JPS5913788A (ja) 1984-01-24
PL242747A1 (en) 1985-01-30
IT8348599A0 (it) 1983-06-29
KR840005150A (ko) 1984-11-03
FI832384A0 (fi) 1983-06-29
FR2543949A1 (fr) 1984-10-12
DE3323450A1 (de) 1984-01-12
ZA834758B (en) 1984-04-25
JPS5913787A (ja) 1984-01-24
IT1173727B (it) 1987-06-24
GB2123415A (en) 1984-02-01
FI832384A7 (fi) 1983-12-31
DK298983D0 (da) 1983-06-29
FR2529556A1 (fr) 1984-01-06
SE8303728L (cs) 1984-12-30
NO832375L (no) 1984-01-02
GB8317618D0 (en) 1983-08-03
AU1638083A (en) 1984-01-05
NL8302308A (nl) 1984-01-16
ES8602019A1 (es) 1985-11-01

Similar Documents

Publication Publication Date Title
CH633292A5 (fr) Oximes derivees de l'acide 3-acetoxymethyl 7-amino thiazolyl acetamido cephalosporanique, procede de preparation et compositions pharmaceutiques.
FR2540875A1 (fr) Nouveaux derives de la cephalosporine et leur procede de preparation
EP0462009B1 (fr) Céphalosporines comportant en position 3 un radical propényle substitué par un ammonium quaternaire, leur procédé de préparation, leur application comme médicaments, les compositions les renfermant et les intermédiaires obtenus
EP0088853B1 (fr) Nouveaux dérivés de pyridinium thiométhyl céphalosporines, procédé pour leur préparation et compositions pharmaceutiques les contenant
FR2563832A1 (fr) Nouveaux derives cephem, procede pour la preparation de ces nouveaux composes, compositions pharmaceutiques contenant au moins un de ces composes et intermediaires de synthese pour leur preparation
CH629815A5 (en) Oximes derived from 7-(aminothiazolylacetamido)cephalosporanic acid, process of preparation and pharmaceutical compositions
LU81884A1 (fr) Cephalosporines a activite antibiotique et procede de preparation
CH638221A5 (fr) Oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et les compositions pharmaceutiques les renfermant.
LU82429A1 (fr) Derives heterocycliques de cephalosporines oxy-imino-substituees
FR2586019A2 (fr) Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur application comme medicaments et les compositions pharmaceutiques les renfermant
CH626370A5 (en) Process for the preparation of the syn isomer or of a mixture of syn and anti isomers of 7beta-acylamidoceph-3-em-4-carboxylic acids with antibiotic activity
LU82285A1 (fr) Antibiotiques du type cephalosporine et procede de preparation
CH651572A5 (fr) Alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl)acetamido cephalosporanique, leur preparation et les compositions les renfermant.
CA1152061A (fr) Procede de preparation de nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
FR2529555A1 (fr) Cephalosporines a activite antibiotique, leur procede de preparation et leur application en therapeutique
CZ403291A3 (en) Cephalosporin derivatives, process for preparing thereof and pharmaceutical preparations containing them
BE897162A (fr) Cephalosporines a activite antibiotique
BE880037A (fr) Cephalosporines a activite antibiotique et procede de preparation
BE1007544A3 (fr) Derives de thioalkylthiocarbacephalosporines.
LU85101A1 (fr) Antibiotiques du genre des cephalosporines
BE882359A (fr) Antibiotiques du type cephalosporine et procede de preparation
BE881870A (fr) Nouvelles cephalosporines qui exercent une activite contre des organismes gram-negatifs
FR2564095A1 (fr) Antibiotiques de cephalosporine, leur preparation et compositions pharmaceutiques les contenant
BE879664A (fr) Nouvelles cephalosporines, leur preparation et compositions les contenant
LU87002A1 (fr) Composes chimiques

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: GLAXO GROUP LTD

Effective date: 19860630