US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
ATE430580T1
(de)
*
|
2001-10-25 |
2009-05-15 |
Genentech Inc |
Glycoprotein-zusammensetzungen
|
WO2003059934A2
(en)
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
ES2545090T3
(es)
|
2001-12-21 |
2015-09-08 |
Human Genome Sciences, Inc. |
Proteínas de fusión de albúmina y GCSF
|
US20070161087A1
(en)
*
|
2003-05-29 |
2007-07-12 |
Wolfgang Glaesner |
Glp-1 fusion proteins
|
EP2368909A1
(en)
*
|
2003-06-12 |
2011-09-28 |
Eli Lilly and Company |
GLP-1 analog fusion proteins
|
SI1729795T1
(sl)
|
2004-02-09 |
2016-04-29 |
Human Genome Sciences, Inc. |
Albuminski fuzijski proteini
|
US20090232807A1
(en)
*
|
2004-12-22 |
2009-09-17 |
Eli Lilly And Company |
Glp-1 analog fusion protein formulations
|
BRPI0609676A2
(pt)
*
|
2005-05-13 |
2011-10-18 |
Lilly Co Eli |
composto de glp-1 peguilado,e, uso do mesmo
|
WO2007012188A1
(en)
*
|
2005-07-27 |
2007-02-01 |
Qinghua Wang |
GLP/1/EXENDM 4 IgG Fc FUSION CONSTRUCTS FOR TREATMENT OF DIABETES
|
CN101277722A
(zh)
|
2005-08-06 |
2008-10-01 |
王庆华 |
用于预防和治疗ⅰ型糖尿病的组合物及方法
|
ES2336575T3
(es)
*
|
2005-09-22 |
2010-04-14 |
Biocompatibles Uk Limited |
Polipeptidos de fusion glp-1 (peptido-1 similar al glucagon) con resistencia aumentada a la peptidasa.
|
EP1948785B1
(en)
*
|
2005-10-24 |
2014-01-15 |
Janssen Biotech, Inc. |
Glp-2 mimetibodies, polypeptides, compositions, methods and uses
|
ES2586236T3
(es)
|
2005-11-04 |
2016-10-13 |
Glaxosmithkline Llc |
Procedimientos para administrar agentes hipoglucémicos
|
CA2913805A1
(en)
*
|
2005-11-07 |
2007-05-18 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting physiological solubility and stability
|
US8841255B2
(en)
|
2005-12-20 |
2014-09-23 |
Duke University |
Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
|
US20130172274A1
(en)
|
2005-12-20 |
2013-07-04 |
Duke University |
Methods and compositions for delivering active agents with enhanced pharmacological properties
|
EP1816201A1
(en)
|
2006-02-06 |
2007-08-08 |
CSL Behring GmbH |
Modified coagulation factor VIIa with extended half-life
|
US8288339B2
(en)
|
2006-04-20 |
2012-10-16 |
Amgen Inc. |
GLP-1 compounds
|
WO2008028117A2
(en)
*
|
2006-08-31 |
2008-03-06 |
Centocor, Inc. |
Glp-2 mimetibodies, polypeptides, compositions, methods and uses
|
MX2009002547A
(es)
*
|
2006-09-06 |
2009-06-19 |
Phasebio Pharmaceuticals Inc |
Composiciones terapeuticas de peptido de fusion.
|
US8338376B2
(en)
*
|
2006-10-20 |
2012-12-25 |
Biogen Idec Ma Inc. |
Compositions comprising variant LT-B-R-IG fusion proteins
|
EP3231440A1
(en)
|
2006-12-22 |
2017-10-18 |
CSL Behring GmbH |
Modified coagulation factors with prolonged in vivo half-life
|
AU2011254001B2
(en)
*
|
2007-01-05 |
2012-08-02 |
Covx Technologies Ireland Limited |
Glucagon-like protein-1 receptor (GLP-1R) agonist compounds
|
JP2008169195A
(ja)
*
|
2007-01-05 |
2008-07-24 |
Hanmi Pharmaceutical Co Ltd |
キャリア物質を用いたインスリン分泌ペプチド薬物結合体
|
US20090098130A1
(en)
*
|
2007-01-05 |
2009-04-16 |
Bradshaw Curt W |
Glucagon-like protein-1 receptor (glp-1r) agonist compounds
|
WO2008086086A2
(en)
*
|
2007-01-05 |
2008-07-17 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting enhanced solubility in physiological ph buffers
|
WO2008098720A1
(en)
|
2007-02-12 |
2008-08-21 |
Csl Behring Gmbh |
Therapeutic application of kazal-type serine protease inhibitors
|
WO2008101017A2
(en)
|
2007-02-15 |
2008-08-21 |
Indiana Unversity Research And Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
EP2139509A2
(en)
*
|
2007-03-15 |
2010-01-06 |
Biogen Idec MA, Inc. |
Treatment of autoimmune disorders
|
KR20100049032A
(ko)
*
|
2007-06-19 |
2010-05-11 |
오츠카 가가쿠 가부시키가이샤 |
당사슬 부가 glp―1 펩티드
|
US7960336B2
(en)
|
2007-08-03 |
2011-06-14 |
Pharmain Corporation |
Composition for long-acting peptide analogs
|
JP2010535781A
(ja)
*
|
2007-08-03 |
2010-11-25 |
イーライ リリー アンド カンパニー |
肥満に対する処置
|
US8563527B2
(en)
*
|
2007-08-20 |
2013-10-22 |
Pharmain Corporation |
Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same
|
EP2031064A1
(de)
*
|
2007-08-29 |
2009-03-04 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Verfahren zur Steigerung von Proteintitern
|
CA2702289A1
(en)
*
|
2007-10-30 |
2009-05-07 |
Indiana University Research And Technology Corporation |
Compounds exhibiting glucagon antagonist and glp-1 agonist activity
|
US8981047B2
(en)
|
2007-10-30 |
2015-03-17 |
Indiana University Research And Technology Corporation |
Glucagon antagonists
|
US20100317057A1
(en)
*
|
2007-12-28 |
2010-12-16 |
Novo Nordisk A/S |
Semi-recombinant preparation of glp-1 analogues
|
WO2009099763A1
(en)
*
|
2008-01-30 |
2009-08-13 |
Indiana University Research And Technology Corporation |
Ester-based peptide prodrugs
|
JOP20190083A1
(ar)
|
2008-06-04 |
2017-06-16 |
Amgen Inc |
بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
|
JP5753779B2
(ja)
*
|
2008-06-17 |
2015-07-22 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
生理学的pHの緩衝液中で向上した溶解性及び安定性を示すグルカゴン類縁体
|
EP2300035B1
(en)
*
|
2008-06-17 |
2015-08-12 |
Indiana University Research and Technology Corporation |
Gip-based mixed agonists for treatment of metabolic disorders and obesity
|
CN103641907A
(zh)
|
2008-06-17 |
2014-03-19 |
印第安纳大学研究及科技有限公司 |
胰高血糖素/glp-1受体共激动剂
|
EP2291523B1
(en)
|
2008-06-24 |
2014-12-17 |
CSL Behring GmbH |
Factor viii, von willebrand factor or complexes thereof with prolonged in vivo half-life
|
EP4074327A1
(en)
|
2008-06-27 |
2022-10-19 |
Duke University |
Therapeutic agents comprising elastin-like peptides
|
JP5878757B2
(ja)
|
2008-10-10 |
2016-03-08 |
アムジエン・インコーポレーテツド |
Fgf21変異体およびその使用
|
WO2010071807A1
(en)
|
2008-12-19 |
2010-06-24 |
Indiana University Research And Technology Corporation |
Amide based glucagon superfamily peptide prodrugs
|
WO2010096394A2
(en)
|
2009-02-17 |
2010-08-26 |
Redwood Biosciences, Inc. |
Aldehyde-tagged protein-based drug carriers and methods of use
|
EP3248610B1
(en)
|
2009-05-05 |
2023-12-20 |
Amgen Inc. |
Fgf21 mutants and uses thereof
|
CA2760674A1
(en)
|
2009-05-05 |
2010-11-11 |
Amgen Inc. |
Fgf21 mutants and uses thereof
|
PE20120914A1
(es)
|
2009-06-16 |
2012-08-22 |
Univ Indiana Res & Tech Corp |
Compuestos glucagon activo de receptor de gip
|
CA2764835A1
(en)
*
|
2009-06-17 |
2010-12-23 |
Amgen Inc. |
Chimeric fgf19 polypeptides and uses thereof
|
CN101993485B
(zh)
|
2009-08-20 |
2013-04-17 |
重庆富进生物医药有限公司 |
促胰岛素分泌肽类似物同源二聚体及其用途
|
WO2011043530A1
(ko)
*
|
2009-10-09 |
2011-04-14 |
(주)알테오젠 |
Glp-1 유사체의 융합체, 및 이를 유효성분으로 함유하는 당뇨병의 예방 또는 치료용 조성물
|
AU2010326024A1
(en)
*
|
2009-12-02 |
2012-07-05 |
Amgen Inc. |
Binding proteins that bind to human FGFR1c, human beta-Klotho and both human FGFR1c and human beta-Klotho
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
WO2011075393A2
(en)
|
2009-12-18 |
2011-06-23 |
Indiana University Research And Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
MX2012008603A
(es)
|
2010-01-27 |
2013-01-25 |
Univ Indiana Res & Tech Corp |
Conjugados de antagonista de glucagon-agonista de gip y composiciones para el tratamiento de desordenes metabolicos y obesidad.
|
EP2371857A1
(en)
|
2010-04-01 |
2011-10-05 |
CSL Behring GmbH |
Factor XII inhibitors for treating interstitial lung disease
|
JP2013523184A
(ja)
|
2010-04-15 |
2013-06-17 |
アムジエン・インコーポレーテツド |
ヒトFGF受容体およびβ−KLOTHO結合性タンパク質
|
WO2011136361A1
(ja)
|
2010-04-30 |
2011-11-03 |
株式会社 三和化学研究所 |
生理活性物質等の生体内安定性向上のためのペプチド及び生体内安定性が向上した生理活性物質
|
BR112012028704A2
(pt)
|
2010-05-13 |
2019-09-24 |
Univ Indiana Res & Tech Corp |
composto de glugagon da superfamília de peptídeos exibindo atividade do receptor com hormônio nuclear, pró fármaco, dímero ou multímero, composição farmacêutica que o compreendem e método de administração do mesmo.
|
CA2797089A1
(en)
|
2010-05-13 |
2011-11-17 |
Indiana University Research And Technology Corporation |
Glucagon superfamily peptides exhibiting g protein-coupled receptor activity
|
CN101891823B
(zh)
|
2010-06-11 |
2012-10-03 |
北京东方百泰生物科技有限公司 |
一种Exendin-4及其类似物融合蛋白
|
KR20130102470A
(ko)
|
2010-06-24 |
2013-09-17 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
아미드계 글루카곤 슈퍼패밀리 펩티드 프로드러그
|
WO2012010553A1
(en)
*
|
2010-07-20 |
2012-01-26 |
Novo Nordisk A/S |
N-terminal modified fgf21 compounds
|
MX2013006304A
(es)
|
2010-12-22 |
2013-07-02 |
Univ Indiana Res & Tech Corp |
Analogos de glucagon que exhiben actividad del receptor gip.
|
WO2012097333A2
(en)
|
2011-01-14 |
2012-07-19 |
Redwood Bioscience, Inc. |
Aldehyde-tagged immunoglobulin polypeptides and method of use thereof
|
EP2497489A1
(en)
|
2011-03-09 |
2012-09-12 |
CSL Behring GmbH |
Factor XII inhibitors for the treatment of silent brain ischemia and ischemia of other organs
|
CA2829037C
(en)
|
2011-03-09 |
2022-05-17 |
Csl Behring Gmbh |
Factor xii inhibitors for the administration with medical procedures comprising contact with artificial surfaces
|
MY163539A
(en)
|
2011-03-29 |
2017-09-15 |
Roche Glycart Ag |
Antibody fc variants
|
US9156902B2
(en)
|
2011-06-22 |
2015-10-13 |
Indiana University Research And Technology Corporation |
Glucagon/GLP-1 receptor co-agonists
|
JP6184404B2
(ja)
|
2011-06-22 |
2017-08-23 |
インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション |
グルカゴン/glp−1レセプターコアゴニスト
|
EP2734552A1
(en)
|
2011-07-22 |
2014-05-28 |
CSL Behring GmbH |
Inhibitory anti -factor xii/xiia monoclonal antibodies and their uses
|
UY34317A
(es)
|
2011-09-12 |
2013-02-28 |
Genzyme Corp |
Anticuerpo antireceptor de célula T (alfa)/ß
|
KR20130049671A
(ko)
|
2011-11-04 |
2013-05-14 |
한미사이언스 주식회사 |
생리활성 폴리펩타이드 결합체 제조 방법
|
KR20140097151A
(ko)
|
2011-11-17 |
2014-08-06 |
인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 |
글루코코르티코이드 수용체 활성을 나타내는 글루카곤 슈퍼패밀리 펩티드
|
EP2623110A1
(en)
|
2012-01-31 |
2013-08-07 |
CSL Behring GmbH |
Factor XII inhibitors for the treatment of neurological inflammatory disorders
|
EP2814502B1
(en)
|
2012-02-15 |
2017-09-13 |
CSL Behring GmbH |
Von willebrand factor variants having improved factor viii binding affinity
|
CA2877358A1
(en)
|
2012-06-21 |
2013-12-27 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting gip receptor activity
|
MY183712A
(en)
|
2012-07-13 |
2021-03-09 |
Roche Glycart Ag |
Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases
|
SG10201701831VA
(en)
*
|
2012-09-12 |
2017-05-30 |
Genzyme Corp |
Fc containing polypeptides with altered glycosylation and reduced effector function
|
US9790268B2
(en)
|
2012-09-12 |
2017-10-17 |
Genzyme Corporation |
Fc containing polypeptides with altered glycosylation and reduced effector function
|
SI3115372T1
(sl)
|
2012-11-27 |
2019-08-30 |
Biomarin Pharmaceutical Inc. |
Tarčni terapevtski fuzijski proteini lizosomalnega encima in njihove uporabe
|
US9474803B2
(en)
|
2012-11-27 |
2016-10-25 |
Alteogen Inc. |
Composition for stabilizing fusion protein in which protein and FC domain are fused
|
CN105188750A
(zh)
|
2013-03-08 |
2015-12-23 |
德国杰特贝林生物制品有限公司 |
治疗和预防远端缺血-再灌注损伤
|
SG10201809779RA
(en)
|
2013-03-11 |
2018-12-28 |
Genzyme Corp |
Site-specific antibody-drug conjugation through glycoengineering
|
EP2970511B1
(en)
|
2013-03-14 |
2020-09-30 |
Indiana University Research and Technology Corporation |
Insulin-incretin conjugates
|
US9580486B2
(en)
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
DK2796145T3
(da)
|
2013-04-22 |
2018-01-29 |
Csl Ltd |
Et kovalent kompleks af von Willebrand-faktor og faktor VIII linket af en disulfidbro
|
KR20160026905A
(ko)
|
2013-06-28 |
2016-03-09 |
체에스엘 베링 게엠베하 |
인자 xii 억제제 및 c1-억제제를 이용한 병용 치료요법
|
CN103408669B
(zh)
*
|
2013-08-01 |
2016-01-20 |
江苏泰康生物医药有限公司 |
Glp-1类似物融合蛋白,及其制备方法和用途
|
CN104592381A
(zh)
*
|
2013-10-31 |
2015-05-06 |
江苏万邦生化医药股份有限公司 |
一种利拉鲁肽中间体多肽的制备方法
|
JP6712230B2
(ja)
|
2014-03-11 |
2020-06-17 |
ノバルティス アーゲー |
リポジストロフィーおよびインスリン産生の欠損またはインスリンシグナル伝達の欠損と関連する代謝性障害を処置する方法
|
DK3129067T5
(da)
|
2014-03-19 |
2024-10-14 |
Genzyme Corp |
Sitespecifik glycomodificering af målsøgningsdele
|
EP3127923B1
(en)
*
|
2014-03-31 |
2021-08-18 |
Hanmi Pharm. Co., Ltd. |
Method for improving solubility of protein and peptide by using immunoglobulin fc fragment linkage
|
WO2015193457A1
(en)
|
2014-06-18 |
2015-12-23 |
Csl Behring Gmbh |
Therapy using a factor xii inhibitor in a neurotraumatic disorder
|
DK3164150T3
(da)
|
2014-07-02 |
2021-02-08 |
CSL Behring Lengnau AG |
Modificeret von willebrand-faktor
|
EA202190903A3
(ru)
|
2014-07-21 |
2021-12-31 |
Делиниа, Инк. |
Молекулы, которые избирательно активируют регуляторные t-клетки, для лечения аутоиммунных заболеваний
|
ES2807260T3
(es)
|
2014-08-11 |
2021-02-22 |
Delinia Inc |
Variantes de IL-2 modificadas que activan selectivamente las células T reguladoras para el tratamiento de enfermedades autoinmunes
|
US10232020B2
(en)
|
2014-09-24 |
2019-03-19 |
Indiana University Research And Technology Corporation |
Incretin-insulin conjugates
|
CN104293834B
(zh)
*
|
2014-10-11 |
2018-03-23 |
上海兴迪金生物技术有限公司 |
GLP‑1或其类似物与抗体Fc片段融合蛋白的制备方法
|
DK3236991T3
(da)
|
2014-12-23 |
2019-08-26 |
Novo Nordisk As |
Fgf21-derivater og anvendelser deraf
|
KR101825048B1
(ko)
*
|
2014-12-31 |
2018-02-05 |
주식회사 제넥신 |
GLP 및 면역글로불린 하이브리드 Fc 융합 폴리펩타이드 및 이의 용도
|
TN2017000432A1
(en)
|
2015-04-10 |
2019-04-12 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
AR105616A1
(es)
|
2015-05-07 |
2017-10-25 |
Lilly Co Eli |
Proteínas de fusión
|
DK3298036T3
(da)
|
2015-05-22 |
2022-06-07 |
CSL Behring Lengnau AG |
Fremgangsmåder til forberedelse af modificeret von Willebrand faktor
|
CA2986626A1
(en)
|
2015-05-22 |
2016-12-01 |
Csl Behring Recombinant Facility Ag |
Truncated von willebrand factor polypeptides for treating hemophilia
|
TWI622596B
(zh)
|
2015-10-26 |
2018-05-01 |
美國禮來大藥廠 |
升糖素受體促效劑
|
KR102668200B1
(ko)
|
2015-10-28 |
2024-05-23 |
주식회사유한양행 |
지속형 fgf21 융합 단백질 및 이를 포함하는 약학적 조성물
|
KR102670157B1
(ko)
|
2015-10-28 |
2024-05-29 |
주식회사유한양행 |
이중 작용 단백질 및 이를 포함하는 약학적 조성물
|
EP3184149A1
(en)
|
2015-12-23 |
2017-06-28 |
Julius-Maximilians-Universität Würzburg |
Soluble glycoprotein v for treating thrombotic diseases
|
CA3009650A1
(en)
|
2015-12-23 |
2017-06-29 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
|
AU2017205776B2
(en)
|
2016-01-07 |
2020-09-10 |
CSL Behring Lengnau AG |
Mutated von Willebrand factor
|
RU2018128582A
(ru)
|
2016-01-07 |
2020-02-11 |
Цсл Беринг Ленгнау Аг |
Мутированный укороченный фактор фон виллебранда
|
US20170204154A1
(en)
|
2016-01-20 |
2017-07-20 |
Delinia, Inc. |
Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
|
AU2017247004B2
(en)
|
2016-04-06 |
2022-07-07 |
Csl Limited |
Method of treating atherosclerosis
|
AU2017257504A1
(en)
|
2016-04-26 |
2018-10-25 |
R.P. Scherer Technologies, Llc |
Antibody conjugates and methods of making and using the same
|
US10336812B2
(en)
|
2016-05-10 |
2019-07-02 |
Janssen Biotech, Inc. |
GDF15 fusion proteins and uses thereof
|
EP3502143A4
(en)
|
2016-08-19 |
2020-07-15 |
Ampsource Biopharma Shanghai Inc. |
BINDING PEPTIDE FOR THE CONSTRUCTION OF A FUSION PROTEIN
|
CN106317226B
(zh)
|
2016-08-19 |
2017-09-05 |
安源医药科技(上海)有限公司 |
用于构建融合蛋白的连接肽
|
CN106279437B
(zh)
|
2016-08-19 |
2017-10-31 |
安源医药科技(上海)有限公司 |
高糖基化人凝血因子viii融合蛋白及其制备方法与用途
|
AU2017359172A1
(en)
|
2016-11-08 |
2019-05-16 |
Delinia, Inc. |
IL-2 variants for the treatment of autoimmune diseases
|
MX2019005380A
(es)
|
2016-11-10 |
2019-08-12 |
Yuhan Corp |
Composicion farmaceutica que comprende proteinas de fusion para prevenir o tratar la hepatitis, la fibrosis hepatica y la cirrosis hepatica.
|
EP3538133B1
(en)
|
2016-11-11 |
2021-02-17 |
CSL Behring Lengnau AG |
Truncated von willebrand factor polypeptides for treating hemophilia
|
CA3043397A1
(en)
|
2016-11-11 |
2018-05-17 |
CSL Behring Lengnau AG |
Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder
|
EP3351262A1
(en)
|
2016-12-30 |
2018-07-25 |
Istanbul Universitesi Rektorlugu |
Curaglutide for in treatment of prediabetes, diabetes, obesity and metabolic diseases associated thereto
|
JOP20190177A1
(ar)
|
2017-01-17 |
2019-07-16 |
Amgen Inc |
طريقة لعلاج أو تحسين اضطرابات أيضية باستخدام مساعدات مستقبل glp-1 مقترنة بمناهضات لمستقبل ببتيد مثبط معوي (gipr)
|
JP7191850B2
(ja)
|
2017-04-21 |
2022-12-19 |
ユーハン・コーポレイション |
デュアル機能タンパク質およびその誘導体を生産するための方法
|
PL3630164T3
(pl)
|
2017-06-01 |
2024-01-29 |
Eli Lilly And Company |
Dulaglutyd do leczenia przewlekłej choroby nerek
|
PL3641800T3
(pl)
|
2017-06-22 |
2024-03-18 |
CSL Behring Lengnau AG |
Modulacja immunogenności fviii przez skrócony vwf
|
EP3684793A1
(en)
|
2017-09-22 |
2020-07-29 |
Regeneron Pharmaceuticals, Inc. |
Glucagon-like peptide 1 receptor agonists and uses thereof
|
KR102589234B1
(ko)
|
2017-11-21 |
2023-10-16 |
일라이 릴리 앤드 캄파니 |
둘라글루티드를 함유하는 조성물 및 사용 방법
|
WO2019119673A1
(zh)
|
2017-12-19 |
2019-06-27 |
北京吉源生物科技有限公司 |
一种双基因修饰的干细胞及其用途
|
US11491235B2
(en)
|
2017-12-22 |
2022-11-08 |
Kb Biomed Inc. |
Oral gene carrier and use thereof
|
WO2019140021A1
(en)
|
2018-01-12 |
2019-07-18 |
Eli Lilly And Company |
Combination therapy
|
JP7475276B2
(ja)
|
2018-02-08 |
2024-04-26 |
サンシャイン・レイク・ファーマ・カンパニー・リミテッド |
Fgf21バリアント、融合タンパク質及びそれらの適用
|
WO2020017916A1
(en)
|
2018-07-19 |
2020-01-23 |
D&D Pharmatech Inc. |
Pharmaceutical composition comprising polypeptide
|
KR20200135618A
(ko)
|
2019-05-23 |
2020-12-03 |
㈜ 디앤디파마텍 |
폴리펩티드를 포함하는 비알코올성 지방간 질환의 예방 또는 치료용 약학 조성물
|
CN110878127B
(zh)
|
2018-09-06 |
2022-06-28 |
浙江柏拉阿图医药科技有限公司 |
长效重组GLP1-Fc-CD47蛋白及其制备和用途
|
CN111234000B
(zh)
*
|
2018-11-28 |
2023-05-26 |
鲁南制药集团股份有限公司 |
艾塞纳肽类似物
|
CN111269312B
(zh)
*
|
2018-12-04 |
2023-05-09 |
鲁南制药集团股份有限公司 |
一种异源融合蛋白质
|
CN109836486B
(zh)
*
|
2019-01-30 |
2020-09-08 |
北京双因生物科技有限公司 |
成纤维生长因子21变体、其融合蛋白及其用途
|
EP3935075A4
(en)
*
|
2019-03-05 |
2023-01-18 |
Sunshine Lake Pharma Co., Ltd. |
POLYPEPTIDIC MOLECULE AND ITS APPLICATION
|
MX2021010737A
(es)
|
2019-03-08 |
2021-09-28 |
Amgen Inc |
Terapia de combinacion por factor de diferenciacion del crecimiento 15.
|
WO2020190591A1
(en)
|
2019-03-15 |
2020-09-24 |
Eli Lilly And Company |
Preserved formulations
|
CA3056663C
(en)
|
2019-04-05 |
2022-10-18 |
Jeffrey S. RIESMEYER |
Use of dulaglutide in reducing risk of cardiovascular events in patients with type 2 diabetes mellitus
|
US20220211808A1
(en)
|
2019-05-17 |
2022-07-07 |
Universitaet Zuerich |
Haptoglobin for use in treating an adverse secondary neurological outcome following a haemorrhagic stroke
|
AU2020300820A1
(en)
|
2019-07-04 |
2022-03-03 |
CSL Behring Lengnau AG |
A truncated von willebrand factor (vWF) for increasing the in vitro stability of coagulation factor VIII
|
EP4045641A1
(en)
|
2019-10-15 |
2022-08-24 |
Eli Lilly and Company |
Recombinantly engineered, lipase/esterase-deficient mammalian cell lines
|
WO2021094344A1
(en)
|
2019-11-11 |
2021-05-20 |
CSL Behring Lengnau AG |
Polypeptides for inducing tolerance to factor viii
|
CN113728013B
(zh)
|
2020-01-11 |
2022-06-14 |
北京质肽生物医药科技有限公司 |
Glp-1和fgf21的融合蛋白的缀合物
|
US11981718B2
(en)
|
2020-05-27 |
2024-05-14 |
Ampsource Biopharma Shanghai Inc. |
Dual-function protein for lipid and blood glucose regulation
|
BR112023003310A2
(pt)
|
2020-08-24 |
2023-05-02 |
Univ Pennsylvania |
Vetores virais que codificam fusões de agonistas do receptor de glp-1 e usos dos mesmos no tratamento de doenças metabólicas
|
CN114106194B
(zh)
*
|
2020-08-31 |
2024-01-16 |
中国科学院天津工业生物技术研究所 |
一种用于治疗糖尿病和/或肥胖症的融合蛋白
|
EP4247416A1
(en)
|
2020-11-20 |
2023-09-27 |
CSL Behring GmbH |
Method for treating antibody-mediated rejection
|
CN114685644A
(zh)
|
2020-12-29 |
2022-07-01 |
苏州康宁杰瑞生物科技有限公司 |
一种人glp-1多肽变体及其应用
|
EP4284407A1
(en)
|
2021-02-01 |
2023-12-06 |
CSL Behring AG |
Method of treating or preventing an adverse secondary neurological outcome following a haemorrhagic stroke
|
KR20240005075A
(ko)
|
2021-05-07 |
2024-01-11 |
체에스엘 베링 아게 |
재조합 합토글로빈 (hp) 베타 쇄를 생산하기 위한 발현 시스템
|
KR20240029769A
(ko)
|
2021-07-06 |
2024-03-06 |
수조우 알파맵 씨오., 엘티디. |
융합단백질 및 이의 응용
|
TW202409070A
(zh)
|
2022-05-18 |
2024-03-01 |
美商普羅托莫科技公司 |
芳族含硼化合物及相關胰島素類似物
|
CN114774496B
(zh)
*
|
2022-06-21 |
2022-10-04 |
北京惠之衡生物科技有限公司 |
一种高密度发酵制备glp-1类似物的方法
|
TW202423475A
(zh)
|
2022-09-02 |
2024-06-16 |
瑞士商Csl貝林股份有限公司 |
用於治療或預防過度勃起反應或勃起功能障礙之血紅素結合蛋白
|
WO2024064842A1
(en)
|
2022-09-21 |
2024-03-28 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating obesity, diabetes, and liver dysfunction
|
WO2024068848A1
(en)
|
2022-09-28 |
2024-04-04 |
Zealand Pharma A/S |
Methods for treating obesity
|
WO2024132147A1
(en)
|
2022-12-22 |
2024-06-27 |
Lifearc |
Galanin-2 receptor agonists
|
US20240318221A1
(en)
|
2023-03-23 |
2024-09-26 |
Eli Lilly And Company |
Methods of producing fc-containing proteins
|