BE2014C053I2 - - Google Patents

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Publication number
BE2014C053I2
BE2014C053I2 BE2014C053C BE2014C053C BE2014C053I2 BE 2014C053 I2 BE2014C053 I2 BE 2014C053I2 BE 2014C053 C BE2014C053 C BE 2014C053C BE 2014C053 C BE2014C053 C BE 2014C053C BE 2014C053 I2 BE2014C053 I2 BE 2014C053I2
Authority
BE
Belgium
Application number
BE2014C053C
Other languages
French (fr)
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of BE2014C053I2 publication Critical patent/BE2014C053I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BE2014C053C 2002-10-11 2014-09-09 BE2014C053I2 (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002298259 2002-10-11
PCT/JP2003/013070 WO2004033463A1 (ja) 2002-10-11 2003-10-10 ２，３−ジヒドロ−６−ニトロイミダゾ[２，１−ｂ]オキサゾール化合物

Publications (1)

Publication Number Publication Date
BE2014C053I2 true BE2014C053I2 (enExample) 2022-08-30

Family

ID=32089299

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2014C053C BE2014C053I2 (enExample) 2002-10-11 2014-09-09

Country Status (26)

Country Link
US (1) US7262212B2 (enExample)
EP (2) EP2570418A3 (enExample)
JP (1) JP4186065B2 (enExample)
KR (1) KR100723847B1 (enExample)
CN (4) CN100366624C (enExample)
AR (4) AR041198A1 (enExample)
AU (1) AU2003272979B2 (enExample)
BE (1) BE2014C053I2 (enExample)
BR (1) BRPI0314344B8 (enExample)
CA (1) CA2497569C (enExample)
CY (2) CY1113578T1 (enExample)
DK (1) DK1555267T3 (enExample)
ES (1) ES2400179T3 (enExample)
FR (1) FR14C0066I2 (enExample)
HU (1) HUS1400046I1 (enExample)
LU (1) LU92517I2 (enExample)
MX (1) MXPA05003674A (enExample)
MY (1) MY139244A (enExample)
PL (3) PL404913A1 (enExample)
PT (1) PT1555267E (enExample)
RU (1) RU2326121C3 (enExample)
SI (1) SI1555267T1 (enExample)
TW (1) TWI347946B (enExample)
UA (1) UA83200C2 (enExample)
WO (1) WO2004033463A1 (enExample)
ZA (1) ZA200501033B (enExample)

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WO2004035547A1 (ja) * 2002-10-15 2004-04-29 Otsuka Pharmaceutical Co., Ltd. １位置換―４―ニトロイミダゾール化合物及びその製造法
US8163753B2 (en) * 2003-10-31 2012-04-24 Otsuka Pharmaceutical Co., Ltd. 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis
JP4761756B2 (ja) * 2003-10-31 2011-08-31 大塚製薬株式会社 ２，３−ジヒドロイミダゾ［２，１−ｂ］オキサゾ−ル化合物
TWI300409B (en) 2004-02-18 2008-09-01 Otsuka Pharma Co Ltd Method for producing 4-nitroimidazole compound
PL1731518T3 (pl) 2004-03-31 2014-11-28 Nippon Soda Co Cykliczny związek aminowy oraz środek zwalczający szkodniki
JP4789966B2 (ja) * 2004-04-09 2011-10-12 大塚製薬株式会社 医薬組成物
JP4787529B2 (ja) * 2004-04-09 2011-10-05 大塚製薬株式会社 医薬組成物
US7408066B2 (en) * 2005-06-20 2008-08-05 Schering Corproation Carbon-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists
EP1906926B1 (en) * 2005-07-28 2010-12-01 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical composition comprising 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole derivatives
TWI368509B (en) * 2005-10-05 2012-07-21 Otsuka Pharma Co Ltd Antituberculous therapeutic drugs and kit containing the same
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WO2007040280A1 (ja) 2005-10-06 2007-04-12 Nippon Soda Co., Ltd. 環状アミン化合物および有害生物防除剤
TW200800268A (en) 2005-11-04 2008-01-01 Otsuka Pharma Co Ltd Medicinal composition showing improved drug absorbability
EP1968961A2 (en) 2005-12-21 2008-09-17 Decode Genetics EHF Biaryl nitrogen heterocycle inhibitors of lta4h for treating inflammation
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JP2007297305A (ja) * 2006-04-28 2007-11-15 Daiso Co Ltd Ｎ−（２，３−エポキシ−２−メチルプロピル）フタルイミドの製造法
EP2125750B1 (en) * 2007-02-26 2014-05-21 Vitae Pharmaceuticals, Inc. Cyclic urea and carbamate inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR070301A1 (es) 2007-05-08 2010-03-31 Otsuka Pharma Co Ltd Compuesto epoxi y metodo para producir el mismo
WO2009017671A1 (en) * 2007-07-26 2009-02-05 Vitae Pharmaceuticals, Inc. Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
WO2009021965A2 (en) * 2007-08-15 2009-02-19 Glaxo Group Limited Substituted quinoline derivatives as h1 receptor antagonists
WO2009050204A1 (en) * 2007-10-16 2009-04-23 Glaxo Group Limited Quinoline derivatives used to treat inflammatory and allergic diseases
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
US8440658B2 (en) 2007-12-11 2013-05-14 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
JP5734666B2 (ja) * 2008-02-11 2015-06-17 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の１，３−オキサアゼパン−２−オン及び１，３−ジアゼパン−２−オン阻害剤
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US9643922B2 (en) 2008-08-18 2017-05-09 Yale University MIF modulators
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TW201039034A (en) * 2009-04-27 2010-11-01 Chunghwa Picture Tubes Ltd Pixel structure and the method of forming the same
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KR20120061771A (ko) * 2009-04-30 2012-06-13 비타이 파마슈티컬즈, 인코포레이티드 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제
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CN102753558B (zh) * 2009-07-31 2014-10-15 全球结核病药物研发联盟 硝基咪唑并噁嗪及其在抗结核治疗中的应用
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JP6532457B2 (ja) * 2013-10-04 2019-06-19 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ ６−ニトロ−２，３−ジヒドロイミダゾ［２，１−ｂ］オキサゾール及びこれらの調製方法
CN103524492A (zh) * 2013-10-23 2014-01-22 中国药科大学 侧链含硝基咪唑基团取代的喹诺酮类化合物、其制备及用途
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CN105732659B (zh) * 2014-12-12 2019-07-16 上海阳帆医药科技有限公司 硝基咪唑类化合物及其制备方法和在制药中的用途
EP3252059A4 (en) * 2015-01-29 2018-07-11 Medshine Discovery Inc. Anti-pulmonary tuberculosis nitroimidazole derivative
CN107406386B (zh) 2015-03-27 2021-06-01 大塚制药株式会社 用于生产1-(4-羟基苯基)-4-(4-三氟甲氧基苯氧基)哌啶或其盐的方法
CN106317072B (zh) * 2015-06-17 2020-03-17 盟科医药技术(上海)有限公司 用于分枝杆菌感染治疗的杂环化合物及其应用
EP3421454B9 (en) 2016-02-26 2023-08-09 Otsuka Pharmaceutical Co., Ltd. Piperidine derivative
CN105859628B (zh) * 2016-04-19 2018-08-07 清远职业技术学院 一种抗菌化合物对n咪唑苯甲醛缩邻甲苯胺希夫碱及其制备方法和应用
RU2019104974A (ru) * 2016-07-22 2020-08-24 Медшайн Дискавери Инк. Кристалл и соль нитроимидазола и способ их изготовления
EP3668879B1 (en) 2017-08-16 2021-09-29 GlaxoSmithKline Intellectual Property Development Limited Novel compounds
JP7522655B2 (ja) 2018-06-11 2024-07-25 大塚製薬株式会社 デラマニド含有組成物
CN109705022A (zh) * 2018-12-28 2019-05-03 上海彩迩文生化科技有限公司 一种芳香胺中间体的制备方法
CN112300192B (zh) * 2019-08-02 2023-08-11 南京长澳医药科技有限公司 硝基咪唑类化合物及其制备方法和用途
CN110483549B (zh) * 2019-08-30 2021-03-05 沈阳药科大学 一种硝基咪唑吡喃类抗结核药物的制备方法
CN110615800A (zh) * 2019-10-16 2019-12-27 李丽丽 硝基咪唑类化合物及其制备方法和用途
CN112156088B (zh) * 2020-10-30 2021-08-31 健民药业集团股份有限公司 一种化合物在制备结核分枝杆菌抑制剂中的用途
CN113603706A (zh) * 2021-08-04 2021-11-05 深圳市泰力生物医药有限公司 德拉马尼的晶型、含有该晶型的活性药物和药物组合物
WO2024024938A1 (ja) 2022-07-29 2024-02-01 大塚製薬株式会社 デラマニド含有固体分散体
CN115368252B (zh) * 2022-09-19 2024-01-12 西北农林科技大学 一种4-胺基酚类衍生物及应用
CN116640106B (zh) * 2023-05-11 2024-03-08 郑州大学 一种苯基哌嗪类化合物及其制备方法、应用
CN119059990B (zh) * 2024-11-01 2025-02-07 安徽昊帆生物有限公司 1-氨基甲酸叔丁酯哌嗪的制备方法

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Also Published As

Publication number Publication date
CA2497569A1 (en) 2004-04-22
JP4186065B2 (ja) 2008-11-26
RU2326121C3 (ru) 2021-09-17
CN100366624C (zh) 2008-02-06
ZA200501033B (en) 2006-06-28
SI1555267T1 (sl) 2013-05-31
CN101172981A (zh) 2008-05-07
EP1555267B1 (en) 2013-01-16
BRPI0314344B1 (pt) 2019-11-26
WO2004033463A1 (ja) 2004-04-22
HK1171018A1 (en) 2013-03-15
CN101255170A (zh) 2008-09-03
PL409525A1 (pl) 2014-11-10
ES2400179T3 (es) 2013-04-08
AU2003272979A1 (en) 2004-05-04
JP2004149527A (ja) 2004-05-27
PL404913A1 (pl) 2013-09-30
MY139244A (en) 2009-09-30
EP1555267A1 (en) 2005-07-20
CY2014041I1 (el) 2016-07-27
EP1555267A4 (en) 2010-08-18
PL376157A1 (en) 2005-12-27
KR100723847B1 (ko) 2007-05-31
DK1555267T3 (da) 2013-02-11
TW200420568A (en) 2004-10-16
AR091771A2 (es) 2015-02-25
PT1555267E (pt) 2013-01-29
AU2003272979B2 (en) 2009-07-23
BRPI0314344B8 (pt) 2021-05-25
EP2570418A3 (en) 2013-07-03
FR14C0066I2 (fr) 2015-05-22
TWI347946B (en) 2011-09-01
US7262212B2 (en) 2007-08-28
UA83200C2 (en) 2008-06-25
CN102532162B (zh) 2015-05-27
AR086485A2 (es) 2013-12-18
HK1085463A1 (zh) 2006-08-25
CA2497569C (en) 2011-05-24
HUS1400046I1 (hu) 2017-04-28
CN102532162A (zh) 2012-07-04
AR089950A2 (es) 2014-10-01
LU92517I2 (fr) 2014-10-13
AR041198A1 (es) 2005-05-04
BR0314344A (pt) 2005-07-12
CY1113578T1 (el) 2016-06-22
RU2326121C2 (ru) 2008-06-10
US20060094767A1 (en) 2006-05-04
CY2014041I2 (el) 2016-07-27
PL217919B1 (pl) 2014-09-30
FR14C0066I1 (enExample) 2014-10-17
KR20050061473A (ko) 2005-06-22
EP2570418A2 (en) 2013-03-20
CN1705670A (zh) 2005-12-07
MXPA05003674A (es) 2005-06-08
RU2005114017A (ru) 2006-01-20

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