BE1003254A5 - Derives de furanne. - Google Patents

Derives de furanne. Download PDF

Info

Publication number
BE1003254A5
BE1003254A5 BE8900773A BE8900773A BE1003254A5 BE 1003254 A5 BE1003254 A5 BE 1003254A5 BE 8900773 A BE8900773 A BE 8900773A BE 8900773 A BE8900773 A BE 8900773A BE 1003254 A5 BE1003254 A5 BE 1003254A5
Authority
BE
Belgium
Prior art keywords
salts
ranitidine
well
furanne
derivatives
Prior art date
Application number
BE8900773A
Other languages
English (en)
French (fr)
Inventor
John Watson Clitherow
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888817098A external-priority patent/GB8817098D0/en
Priority claimed from GB898904686A external-priority patent/GB8904686D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of BE1003254A5 publication Critical patent/BE1003254A5/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE8900773A 1988-07-18 1989-07-17 Derives de furanne. BE1003254A5 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888817098A GB8817098D0 (en) 1988-07-18 1988-07-18 Chemical compounds
GB898904686A GB8904686D0 (en) 1989-03-01 1989-03-01 Chemical compounds

Publications (1)

Publication Number Publication Date
BE1003254A5 true BE1003254A5 (fr) 1992-02-11

Family

ID=26294175

Family Applications (1)

Application Number Title Priority Date Filing Date
BE8900773A BE1003254A5 (fr) 1988-07-18 1989-07-17 Derives de furanne.

Country Status (35)

Country Link
US (1) US5008256A (enExample)
JP (1) JP2523185B2 (enExample)
KR (1) KR0122598B1 (enExample)
CN (1) CN1022626C (enExample)
AT (1) AT398200B (enExample)
AU (1) AU632052B2 (enExample)
BE (1) BE1003254A5 (enExample)
CA (1) CA1332610C (enExample)
CH (1) CH679582A5 (enExample)
CY (1) CY1650A (enExample)
DE (1) DE3923638C2 (enExample)
DK (1) DK168381B1 (enExample)
EG (1) EG19368A (enExample)
ES (1) ES2014175A6 (enExample)
FI (1) FI90538C (enExample)
FR (1) FR2634122B1 (enExample)
GB (1) GB2220937B (enExample)
GR (1) GR1000431B (enExample)
HK (1) HK61392A (enExample)
HU (2) HU206104B (enExample)
IE (1) IE61076B1 (enExample)
IL (1) IL91005A (enExample)
IT (1) IT1231481B (enExample)
LU (2) LU87557A1 (enExample)
MX (1) MX174145B (enExample)
MY (1) MY104055A (enExample)
NL (2) NL192604C (enExample)
NO (2) NO176319C (enExample)
NZ (1) NZ229958A (enExample)
PL (1) PL162391B1 (enExample)
PT (1) PT91188B (enExample)
SE (1) SE468715B (enExample)
SG (1) SG51992G (enExample)
YU (1) YU47021B (enExample)
ZW (1) ZW8689A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85472A (en) * 1987-03-09 1991-06-30 Procter & Gamble Pharmaceutical compositions for treating gastrointestinal disorders
ATE81011T1 (de) * 1987-03-09 1992-10-15 Procter & Gamble Zusammensetzungen und ihre verwendung zur behandlung von magen-darmstoerungen.
AU641903B2 (en) * 1988-10-26 1993-10-07 Glaxo Group Limited Carboxylic acid derivatives
GB9004328D0 (en) * 1990-02-27 1990-04-25 Glaxo Group Ltd Chemical compounds
GB9009240D0 (en) * 1990-04-25 1990-06-20 Glaxo Group Ltd Chemical compounds
GB9009437D0 (en) * 1990-04-26 1990-06-20 Glaxo Group Ltd Chemical compounds
HUT64080A (en) * 1990-07-20 1993-11-29 Slagel David Process for produicng bismuth-polyacrylate complexes and pharmaceutical compositions comprising same as active ingredient
GB9019875D0 (en) * 1990-09-11 1990-10-24 Glaxo Group Ltd Pharmaceutical compositions
US5192752A (en) * 1991-01-14 1993-03-09 The Procter & Gamble Company Swallowable pharmaceutical compositions containing colloidal bismuth subcitrate
US5128140A (en) * 1991-01-14 1992-07-07 The Procter & Gamble Company Swallowable pharmaceutical compositions
GB9120131D0 (en) * 1991-09-20 1991-11-06 Glaxo Group Ltd Medicaments
ES2130152T3 (es) * 1991-12-06 1999-07-01 Glaxo Group Ltd Medicamentos para tratar dolencias inflamatorias o para analgesia que contienen un nsaid y ranitidina/citrato de bismuto.
CZ287159B6 (en) * 1992-10-27 2000-10-11 Janssen Pharmaceutica Nv 4-Quinolyl derivatives per se and for use as medicaments, process of their preparation and pharmaceutical preparations based thereon
WO1996019232A1 (en) * 1994-12-19 1996-06-27 Lauteral Limited Combinations of ranitidine hydrochloride-form 1 and bismuth compounds
GB9501560D0 (en) 1995-01-26 1995-03-15 Nycomed Imaging As Contrast agents
HUP9900428A2 (hu) * 1995-01-26 1999-06-28 Nycomed Imaging A/S Bizmutvegyületek, ezeket tartalmazó diagnosztikai kontrasztanyag, ennek alkalmazása és ezt tartalmazó gyógyászati készítmény
RU2131264C1 (ru) * 1996-06-04 1999-06-10 Московское производственное химико-фармацевтическое объединение им.Н.А.Семашко Противоязвенное средство в виде таблеток и способ его получения
EP1035192A1 (de) * 1999-01-26 2000-09-13 Stefan Graichen Additiv für einen Kühlschmierstoff
CN1102585C (zh) * 1999-04-28 2003-03-05 常州兰陵制药有限公司 雷尼替丁枸橼酸铋盐的制备方法
US20060100271A1 (en) * 2004-11-08 2006-05-11 Keith Whitehead Stabilized aqueous ranitidine compositions
CN100402514C (zh) * 2006-08-01 2008-07-16 丽珠医药集团股份有限公司 一种制备枸橼酸铋雷尼替丁的方法
AU2007216671B2 (en) * 2007-07-09 2009-07-16 Cypress Pharmaceutical, Inc. Pleasant-tasting ranitidine formulation
CN102408398B (zh) * 2011-09-20 2012-12-05 江苏汉斯通药业有限公司 枸橼酸铋雷尼替丁的制备方法
US9731999B2 (en) 2011-09-23 2017-08-15 Iqbal Gill Chemical admixtures for hydraulic cements
ES2426539B1 (es) * 2012-04-18 2014-09-09 Dr Healthcare España, S. L. Uso de la diaminooxidasa para el tratamiento o la prevención del trastorno por deficit de atencion con hiperactividad (adhd)
CN103896888B (zh) * 2014-03-28 2015-11-18 常州兰陵制药有限公司 枸橼酸铋雷尼替丁的制备方法
WO2015155297A1 (en) 2014-04-11 2015-10-15 Sanovel Ilac Sanayi Ve Ticaret A.S. Pharmaceutical combinations of dabigatran and h2-receptor antagonists
WO2015169957A1 (en) 2014-05-09 2015-11-12 Sanovel Ilac Sanayi Ve Ticaret A.S. Pharmaceutical combinations of rivaroxaban and h2-receptor antagonists
CN107382921B (zh) * 2017-07-28 2025-04-18 常州兰陵制药有限公司 制备枸橼酸铋雷尼替丁的方法
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565967A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
BE905235A (fr) * 1986-08-05 1986-12-01 Hasunor Ag Ascorbates antagonistes des recepteurs h2 et leur procede de preparation.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531706A1 (fr) * 1982-08-13 1984-02-17 Sanofi Sa Benzamides, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant
IT1215325B (it) * 1987-01-07 1990-02-08 Barisintex Sa Composti antagonisti di recettori -h2 e procedimento per la loro preparazione.
ATE81011T1 (de) * 1987-03-09 1992-10-15 Procter & Gamble Zusammensetzungen und ihre verwendung zur behandlung von magen-darmstoerungen.
IL85472A (en) * 1987-03-09 1991-06-30 Procter & Gamble Pharmaceutical compositions for treating gastrointestinal disorders
DE3710462A1 (de) * 1987-03-30 1988-10-13 Heumann Pharma Gmbh & Co Pharmazeutische zubereitung zur behandlung von erkrankungen des magen-darm-traktes
GB9004328D0 (en) * 1990-02-27 1990-04-25 Glaxo Group Ltd Chemical compounds
GB9009437D0 (en) * 1990-04-26 1990-06-20 Glaxo Group Ltd Chemical compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565967A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
BE905235A (fr) * 1986-08-05 1986-12-01 Hasunor Ag Ascorbates antagonistes des recepteurs h2 et leur procede de preparation.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 108, no. 19, 9 mai 1988, page 47, colonne 1, abrégé no. 161242u, Columbus, Ohio, US; "G. BIANCHI PORRO et al.: "Why are nonsteroidal anti-inflammatory drugs important in peptic ulceration?", & ALIMENT. PHARMACOL. THER. 1987, 1(Suppl. 1), 540S-547S *

Also Published As

Publication number Publication date
SE8902550L (sv) 1990-01-19
ES2014175A6 (es) 1990-06-16
GR1000431B (el) 1992-07-30
PL162391B1 (pl) 1993-10-30
NL192604C (nl) 1997-11-04
HU211173A9 (en) 1995-11-28
SE468715B (sv) 1993-03-08
NO892936L (no) 1990-01-19
IT1231481B (it) 1991-12-07
JPH02117684A (ja) 1990-05-02
YU142789A (en) 1991-04-30
ATA172889A (de) 1994-02-15
CN1022626C (zh) 1993-11-03
DK351789A (da) 1990-01-19
CA1332610C (en) 1994-10-18
NL192604B (nl) 1997-07-01
HK61392A (en) 1992-08-21
CN1039419A (zh) 1990-02-07
NL8901840A (nl) 1990-02-16
DE3923638A1 (de) 1990-03-01
PT91188B (pt) 1995-03-01
LU88722I2 (fr) 1996-08-23
SE8902550D0 (sv) 1989-07-17
DK351789D0 (da) 1989-07-17
MY104055A (en) 1993-10-30
FI893448L (fi) 1990-01-19
YU47021B (sh) 1994-11-15
HU206104B (en) 1992-08-28
ZW8689A1 (en) 1990-02-21
AT398200B (de) 1994-10-25
FI90538B (fi) 1993-11-15
EG19368A (en) 1995-02-28
JP2523185B2 (ja) 1996-08-07
NO892936D0 (no) 1989-07-17
GB2220937A (en) 1990-01-24
MX174145B (es) 1994-04-25
IE61076B1 (en) 1994-09-21
IL91005A (en) 1994-10-07
CH679582A5 (enExample) 1992-03-13
SG51992G (en) 1992-07-24
KR0122598B1 (ko) 1997-11-13
NL970046I2 (nl) 1998-04-01
IL91005A0 (en) 1990-02-09
FI893448A0 (fi) 1989-07-17
DE3923638C2 (de) 1995-11-23
KR910002826A (ko) 1991-02-26
NO176319B (no) 1994-12-05
IE892309L (en) 1990-01-18
GB2220937B (en) 1991-11-27
GB8916288D0 (en) 1989-08-31
PT91188A (pt) 1990-02-08
NO176319C (no) 1995-03-15
GR890100454A (en) 1990-06-27
US5008256A (en) 1991-04-16
HUT52082A (en) 1990-06-28
IT8948196A0 (it) 1989-07-17
FR2634122A1 (fr) 1990-01-19
NO1998007I1 (no) 1998-02-05
NL970046I1 (nl) 1998-03-02
MX16829A (es) 1993-10-01
FR2634122B1 (fr) 1993-11-19
CY1650A (en) 1992-12-11
NZ229958A (en) 1991-09-25
LU87557A1 (fr) 1990-07-24
FI90538C (fi) 1994-02-25
AU632052B2 (en) 1992-12-17
AU3817889A (en) 1990-01-18
DK168381B1 (da) 1994-03-21

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Legal Events

Date Code Title Description
RE Patent lapsed

Effective date: 20060731

CCRE Expiry of a supplementary protection certificate

Free format text: PRODUCT NAME: RANITIDINE BISMUTH CITRATE; NAT. REGISTRATION NO/DATE: 5505 IE 1 F 3 19960426; FIRST REGISTRATION: GB PL 14213/0001 19950714

Spc suppl protection certif: 96C0017

Filing date: 19960521

Expiry date: 20090717

Extension date: 20100714

Effective date: 20100714