ATE110259T1 - Wässerige arzneisuspension für im wesentlichen wasserunlösliche arzneiwirkstoffe. - Google Patents

Wässerige arzneisuspension für im wesentlichen wasserunlösliche arzneiwirkstoffe.

Info

Publication number
ATE110259T1
ATE110259T1 AT90307001T AT90307001T ATE110259T1 AT E110259 T1 ATE110259 T1 AT E110259T1 AT 90307001 T AT90307001 T AT 90307001T AT 90307001 T AT90307001 T AT 90307001T AT E110259 T1 ATE110259 T1 AT E110259T1
Authority
AT
Austria
Prior art keywords
essentially water
suspension
aqueous
medication suspension
effective amount
Prior art date
Application number
AT90307001T
Other languages
English (en)
Inventor
Walter G Gowan Jr
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Application granted granted Critical
Publication of ATE110259T1 publication Critical patent/ATE110259T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT90307001T 1989-06-28 1990-06-27 Wässerige arzneisuspension für im wesentlichen wasserunlösliche arzneiwirkstoffe. ATE110259T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37273489A 1989-06-28 1989-06-28

Publications (1)

Publication Number Publication Date
ATE110259T1 true ATE110259T1 (de) 1994-09-15

Family

ID=23469412

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90307001T ATE110259T1 (de) 1989-06-28 1990-06-27 Wässerige arzneisuspension für im wesentlichen wasserunlösliche arzneiwirkstoffe.

Country Status (17)

Country Link
US (2) US5374659A (de)
EP (1) EP0405930B1 (de)
JP (1) JP2874967B2 (de)
KR (1) KR0161969B1 (de)
AT (1) ATE110259T1 (de)
AU (1) AU635283B2 (de)
CA (1) CA2019863C (de)
DE (1) DE69011766T2 (de)
ES (1) ES2064634T3 (de)
GR (1) GR1002094B (de)
GT (1) GT199000066A (de)
HK (1) HK127494A (de)
IE (1) IE64400B1 (de)
IL (1) IL94887A (de)
NZ (1) NZ234143A (de)
PT (1) PT94504B (de)
ZA (1) ZA905058B (de)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0662320B1 (de) * 1991-08-30 2001-05-30 Showa Yakuhin Kako Co., Ltd. Trockene gelzusammensetzung
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
FI941777L (fi) * 1993-04-16 1994-10-17 Mcneil Ppc Inc Vesipitoinen farmaseuttinen suspensio ja menetelmä sen valmistamiseksi
FR2713931B1 (fr) * 1993-12-20 1996-04-05 Laurence Paris Nouvelles compositions pharmaceutiques liquides à base d'ibuprofène et leur procédé de préparation.
NZ272574A (en) * 1995-07-14 1999-02-25 Lilly Eli & Co Nz Ltd Aqueous base suspension concentrate containing at least one ionophore antibiotic and wetting agent and/or a surfactant and xanthan gum optionally with a suspension agent, an antifreeze agent and an antifoaming agent; drench for veterinary treatment
DK0839024T3 (da) * 1995-07-14 2004-08-16 Elli Lilly & Co Nz Ltd Ionofore antibiotiske formuleringer
NZ280384A (en) 1995-11-02 1997-01-29 Lilly Eli & Co Nz Ltd Animal feed supplement comprising a wettable powder composition of an ionophore antibiotic
AUPN862596A0 (en) * 1996-03-12 1996-04-04 F.H. Faulding & Co. Limited Pharmaceutical compositions
US6231890B1 (en) 1996-05-02 2001-05-15 Taisho Pharmaceutical Co., Ltd. Suspension of sparingly water-soluble acidic drug
US5712310A (en) * 1996-06-14 1998-01-27 Alpharma Uspd, Inc. Suspension of substantially water-insoluble drugs and methods of their manufacture
EP1210880B8 (de) * 1998-10-28 2009-06-03 San-Ei Gen F.F.I., Inc. Sukralose enthaltende zusammensetzungen sowie deren verwendung
US20110189348A1 (en) * 1998-10-28 2011-08-04 San-Ei Gen F.F.I., Inc. Compositions containing sucralose and application thereof
USH2044H1 (en) 1998-11-02 2002-09-03 Mcneil-Ppc, Inc. Container with retaining member
PT1165042E (pt) 1999-04-06 2005-06-30 Ethypharm Sa Suspensao farmaceutica bebivel de ibuprofeno
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
US6726922B1 (en) 1999-06-28 2004-04-27 Minu, L.L.C. Process and composition for temporarily suppressing pain
ATE311119T1 (de) 2000-05-31 2005-12-15 Pepsico Inc Verschmutzungsarme orange nahrungsmittelfarbstoffzusammensetzung
NZ524348A (en) * 2000-08-02 2004-07-30 Malope Company Ltd Diagnosis and treatment of non-ulcer dyspepsia based on dysfunction in the corticotropin releasing hormone (CRH) receptor and repsonse to ACTH
JP4204864B2 (ja) * 2000-12-25 2009-01-07 ライオン株式会社 懸濁液の安定化方法及び安定化された懸濁液
PT1232746E (pt) * 2001-02-14 2006-11-30 Forte Iq B V Composição farmacêutica que compreende goma xantana
JP2004535370A (ja) 2001-03-05 2004-11-25 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 味をマスクした液体製薬学的組成物
PL212985B1 (pl) * 2001-04-03 2012-12-31 Schering Corp Ciekla zawiesina zawierajaca przeciwgrzybiczo skuteczna ilosc posakonazolu oraz zastosowanie zmikronizowanych czastek posakonazolu
EP1411955A4 (de) * 2001-07-31 2006-07-05 Wyeth Corp Sucralose-formulierungen zur überdeckung von unangenehmem geschmack
US6770263B1 (en) * 2001-10-01 2004-08-03 Naturewell, Incorporated Compositions and methods for the treatment of aches and pains
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
ES2197781B1 (es) * 2001-12-04 2005-02-16 Farmalider, S.A. Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno.
US6998480B2 (en) 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US7049435B2 (en) 2002-03-08 2006-05-23 Tate & Lyle Public Limited Company Extractive methods for purifying sucralose
US7300670B2 (en) 2002-04-03 2007-11-27 Unilab Pharmatech, Ltd. Oral suspension formulation
ATE541562T1 (de) * 2002-06-17 2012-02-15 Taro Pharmaceuticals Usa Inc Ibuprofen-suspension
US20030232097A1 (en) * 2002-06-17 2003-12-18 Strides Inc. Oily wax matrix suspension formulation comprising ibuprofen free acid and potassium salt of ibuprofen
KR100509432B1 (ko) * 2002-12-13 2005-08-22 주식회사 동구제약 S(+)-이부프로펜을 함유한 시럽제 조성물 및 그의 제조방법
TWI313598B (en) * 2002-12-18 2009-08-21 Wyeth Corp Compositions of non-steroidal anti-inflammatory drugs, decongestants and anti-histamines
US20040253311A1 (en) * 2002-12-18 2004-12-16 Roger Berlin Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
KR101059057B1 (ko) * 2003-09-12 2011-08-24 류가쿠산 가부시키가이샤 쓴맛을 차단할 수 있는 과립상 젤리 음료
US20050069590A1 (en) * 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20060088593A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070190133A1 (en) * 2004-10-27 2007-08-16 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US8383159B2 (en) * 2004-10-27 2013-02-26 Mcneil-Ppc, Inc. Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070281022A1 (en) * 2004-10-27 2007-12-06 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060087051A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088587A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088586A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060093629A1 (en) 2004-10-29 2006-05-04 Buehler Gail K Dye-free pharmaceutical suspensions and related methods
US20060093631A1 (en) * 2004-10-29 2006-05-04 Buehler Gail K Dye-free pharmaceutical suspensions and related methods
US20060093630A1 (en) * 2004-10-29 2006-05-04 Buehler Gail K Dye-free pharmaceutical suspensions and related methods
US20060094760A1 (en) * 2004-11-04 2006-05-04 Fawzy Abdel A Composition, system and method of treatment of gastrointestinal disorders with nizatidine oral solution
US7611695B2 (en) * 2004-11-15 2009-11-03 Ultradent Products, Inc. Flavored hemostatic and acid etching compositions
US8758816B2 (en) * 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
PL2486942T3 (pl) 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
PL1824493T3 (pl) 2004-12-06 2009-01-30 Janssen Pharmaceutica Nv Zawiesina zawierająca meloksykam do podawania doustnego
ATE536867T1 (de) * 2006-03-16 2011-12-15 Tris Pharma Inc Modifizierte freisetzungsformulierungen mit arznei-ion-austausch-harzkomplexen
GB2438287A (en) * 2006-05-19 2007-11-21 Norbrook Lab Ltd Stable aqueous suspension
US20080014275A1 (en) * 2006-07-13 2008-01-17 Buehler Gail K Pharmaceutical suspensions and related methods
BRPI0719021A2 (pt) 2006-11-21 2013-12-17 Mcneil-Ppc, Inc. Suspensões analgésicas de liberação modificada.
CA2677076C (en) * 2007-03-02 2017-09-12 Meda Pharmaceuticals Inc. Compositions comprising carisoprodol and methods of use thereof
EP2121868B1 (de) * 2007-03-09 2014-05-07 Hercules Incorporated Stabile und fluidisierte polymersuspensionen auf natrium-thiosulfat-basis aus hydroxyethyl-zellulose für operationen auf ölfeldern
US20080260837A1 (en) * 2007-04-20 2008-10-23 Qpharma, L.L.C. Physically stable aqueous suspensions of active pharmaceuticals
US20080268025A1 (en) * 2007-04-25 2008-10-30 Donald Spector Compositions Useful for Preventing Pain and Soreness Resulting from Exercise and Methods of Use
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
WO2009085959A1 (en) 2007-12-20 2009-07-09 Organic Recovery, Llc Methods and compositions for digestion of organic waste
KR20110065417A (ko) * 2008-01-03 2011-06-15 욱크하르트 리미티드 파라세타몰 및 이부프로펜을 포함하는 경구 약제학적 현탁액
AR070082A1 (es) * 2008-01-04 2010-03-10 Tate & Lyle Technology Ltd Metodo para la produccion de sucralosa
WO2009117317A1 (en) * 2008-03-20 2009-09-24 Tate & Lyle Technology Ltd Removal of acids from tertiary amide solvents
US8436157B2 (en) * 2008-03-26 2013-05-07 Tate & Lyle Technology Limited Method for the production of sucralose
US8497367B2 (en) * 2008-04-03 2013-07-30 Tate & Lyle Technology Limited Sucralose purification process
US20090299055A1 (en) * 2008-04-03 2009-12-03 Tate & Lyle Technology Limited Purification of Sucralose Containing Feed Streams for Sucralose Crystallization
US20090259036A1 (en) * 2008-04-03 2009-10-15 Tate & Lyle Technology Limited Extraction of less polar impurities from sucralose containing aqueous feed streams
AR071134A1 (es) * 2008-04-03 2010-05-26 Tate & Lyle Technology Ltd Cristalizacion de sucralosa a partir de chorros que contienen sucralosa
US8212022B2 (en) * 2008-04-03 2012-07-03 Tate & Lyle Technology Limited Effect of carbohydrate concentration on sucralose extraction efficiency
CN102264736B (zh) 2008-10-22 2013-08-14 阵列生物制药公司 作为TRK激酶抑制剂的取代的吡唑并[1,5-a]嘧啶化合物
PE20120647A1 (es) * 2009-03-13 2012-05-31 Nucitec Sa De Cv Composiciones y metodos para el tratamiento y prevencion de la enfermedad cardiovascular
GB2469158B (en) 2009-03-31 2011-09-28 Peter J Seaberg Base-assisted formation of tin-sucrose adducts
AR077468A1 (es) 2009-07-09 2011-08-31 Array Biopharma Inc Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
GB2474310B (en) 2009-10-12 2012-02-29 Tate & Lyle Technology Ltd Process for the production of sucrose-6-ester
GB2474311B (en) 2009-10-12 2012-10-17 Tate & Lyle Technology Ltd Low temperature, single solvent process for the production of sucrose-6-ester
GB201110520D0 (en) 2011-05-10 2011-08-03 Tate & Lyle Technology Ltd Extraction of carboxylic acids with tin compounds
DK3139769T3 (da) 2014-05-05 2022-08-01 California Safe Soil Llc Næringsrige sammensætninger
TWI746426B (zh) 2014-11-16 2021-11-21 美商亞雷生物製藥股份有限公司 (S)-N-(5-((R)-2-(2,5-二氟苯基)-吡咯啶-1-基)-吡唑并[1,5-a]嘧啶-3-基)-3-羥基吡咯啶-1-甲醯胺硫酸氫鹽結晶型
EP3061501A1 (de) 2015-02-27 2016-08-31 Rottapharm Ltd. Zusammensetzung zur behandlung von akne
EP3117825A1 (de) 2015-07-16 2017-01-18 Rottapharm S.p.A. Orale formulierung mit berberin und morus-alba-extrakt
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
EP3368039A1 (de) 2015-10-26 2018-09-05 The Regents of The University of Colorado, A Body Corporate Punktmutationen bei trk-inhibitor-resistentem krebs und zugehörige verfahren
UA125025C2 (uk) 2016-04-04 2021-12-29 Локсо Онколоджі, Інк. Способи лікування дитячих ракових захворювань
UA125026C2 (uk) 2016-04-04 2021-12-29 Локсо Онколоджі, Інк. РІДКІ КОМПОЗИЦІЇ (S)-N-(5-((R)-2-(2,5-ДИФТОРФЕНІЛ)ПІРОЛІДИН-1-ІЛ)ПІРАЗОЛО[1,5-a]ПІРИМІДИН-3-ІЛ)-3-ГІДРОКСИПІРОЛІДИН-1-КАРБОКСАМІДУ
MX392604B (es) 2016-05-18 2025-03-24 Array Biopharma Inc Procesos para la preparacion de (s)-n-(5-((r)-2-(2,5-difluorofenil)pirrolidin-1-il)-pirazolo[1,5-a]pirimidin-3-il)-3-hidroxipirrolidin-1-carboxamida y sales del mismo.
JOP20190092A1 (ar) 2016-10-26 2019-04-25 Array Biopharma Inc عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها
JOP20190213A1 (ar) 2017-03-16 2019-09-16 Array Biopharma Inc مركبات حلقية ضخمة كمثبطات لكيناز ros1
WO2019045005A1 (ja) * 2017-08-31 2019-03-07 国立大学法人東北大学 リンパ行性薬剤送達法に有効な薬剤を含む溶液の適正な浸透圧域
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
US12458592B1 (en) 2017-09-24 2025-11-04 Tris Pharma, Inc. Extended release amphetamine tablets
CA3080157A1 (en) * 2017-10-26 2019-05-02 Array Biopharma Inc. Formulations of a macrocyclic trk kinase inhibitor
GB2585825B (en) * 2019-07-09 2023-03-22 Lexon Uk Holdings Ltd Suspending vehicle formulation
RS65089B1 (sr) * 2019-12-23 2024-02-29 Nutra Essential Otc S L Tečna kompozicija koja sadrži ibuprofen i fenilefrin
CN112516083B (zh) * 2020-12-15 2023-02-28 太阳升(亳州)生物医药科技有限公司 布洛芬混悬液及其制备方法
CN120916748A (zh) 2023-03-31 2025-11-07 科赴品牌有限责任公司 治疗性悬浮液组合物
EP4687840A1 (de) 2023-03-31 2026-02-11 Kenvue Brands LLC Flüssige therapeutische zusammensetzungen
US20250110097A1 (en) 2023-09-29 2025-04-03 Kenvue Brands Llc Method for evaluating homogeneity of oral suspensions

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
US3911128A (en) * 1972-02-07 1975-10-07 Sandoz Ag Substituted purines as hypolipidemics
US3852257A (en) * 1973-02-05 1974-12-03 Kelco Co Suspension polymerization in the presence of xanthan gum
US4447454A (en) * 1977-04-01 1984-05-08 The Upjohn Company Analgetic compounds, compositions and process of treatment
US4145440A (en) * 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
CA1167403A (en) * 1979-07-10 1984-05-15 Unilever Limited Microbial heteropolysaccharide
US4329448A (en) * 1979-07-10 1982-05-11 Lever Brothers Company Microbial heteropolysaccharide
JPS5846483B2 (ja) * 1979-09-20 1983-10-17 ライオン株式会社 口腔用組成物
JPS5835965B2 (ja) * 1979-07-31 1983-08-05 ライオン株式会社 口腔用組成物
US4251560A (en) * 1979-08-21 1981-02-17 General Foods Corporation Cream-containing frozen whipped topping composition
US4361580A (en) * 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
US4346108A (en) * 1981-06-22 1982-08-24 The Upjohn Manufacturing Company M Method for preventing adhesion formation
US4542158A (en) * 1981-12-21 1985-09-17 Merck & Co., Inc. Prodrug esters of diflunisal and related compounds
US4762709A (en) * 1983-09-16 1988-08-09 Pennwalt Corporation Liquid prolonged release pharmaceutical formulations containing ionic constituents
IT1183574B (it) * 1985-05-08 1987-10-22 Eurand Spa Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
US4744986A (en) * 1986-03-07 1988-05-17 Rorer Pharmaceutical Corporation Process for the preparation of a viscosity-stable antacid composition
US4761274A (en) * 1986-03-27 1988-08-02 Warner-Lambert Company Medicament adsorbates of analgesics with complex magnesium aluminum silicate and their preparation
GB8609566D0 (en) * 1986-04-18 1986-05-21 Boots Co Plc Analgesic method
US4684666A (en) * 1986-08-19 1987-08-04 Haas Pharmaceuticals, Inc. Stabilized liquid analgesic compositions
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
US4975465A (en) * 1989-03-28 1990-12-04 American Home Products Corporation Orally administrable ibuprofen compositions

Also Published As

Publication number Publication date
US5374659A (en) 1994-12-20
ZA905058B (en) 1992-02-26
KR910000124A (ko) 1991-01-29
IE902332A1 (en) 1991-01-16
IL94887A (en) 1994-11-11
CA2019863A1 (en) 1990-12-28
PT94504A (pt) 1991-02-08
HK127494A (en) 1994-11-25
GR900100481A (el) 1991-11-15
JP2874967B2 (ja) 1999-03-24
EP0405930A2 (de) 1991-01-02
EP0405930B1 (de) 1994-08-24
KR0161969B1 (ko) 1998-12-01
US5621005A (en) 1997-04-15
ES2064634T3 (es) 1995-02-01
DE69011766T2 (de) 1994-12-22
GT199000066A (es) 1992-04-09
GR1002094B (en) 1995-12-28
CA2019863C (en) 1996-06-04
IE902332L (en) 1990-12-28
AU635283B2 (en) 1993-03-18
DE69011766D1 (de) 1994-09-29
IL94887A0 (en) 1991-04-15
JPH0363219A (ja) 1991-03-19
EP0405930A3 (en) 1991-09-04
NZ234143A (en) 1991-10-25
AU5792690A (en) 1991-02-07
IE64400B1 (en) 1995-08-09
PT94504B (pt) 1997-02-28

Similar Documents

Publication Publication Date Title
DE69011766D1 (de) Wässerige Arzneisuspension für im wesentlichen wasserunlösliche Arzneiwirkstoffe.
CA2089430A1 (en) Aqueous pharmaceutical suspension for pharmaceutical active
CA2121435A1 (en) Aqueous pharmaceutical suspension and process for preparation thereof
TNSN95098A1 (fr) Derives de cycloalcanoindoles et de cycloalcanoaza-indoles
ZA845541B (en) Aqueous solution containing lipid-soluble pharmaceutical substance
EP0270362A3 (de) Pyridinyl-Pyrimidin-Derivate, Verfahren zu deren Herstellung und diese als wirksamen Stoff enthaltendes fungicides Mittel
KR940021071A (ko) 생체기능조정물질
ES2128051T3 (es) Isomero de doble enlace de la equilina, procedente de la isomerizacion acida de la equilina.
HUT59832A (en) Process for producing pharmaceutical compositions containing calcitonin
HU9201789D0 (en) Process for the production of substituted diamino-phtalimides and their analogues
PT1067934E (pt) Solucao anti-depressiva liquida oral
BE1002239A5 (fr) Solution pharmaceutique.
HUT51283A (en) Process for production of n-alkyl derivatives of bu-3608-antibiotics and medical compositions containing them as active substances
AU618896B2 (en) Stable solutions of rebeccamycin analog and preparation thereof
HUT77560A (hu) Trombin inhibitort tartalmazó, tárolás közben stabil, vizes, infúziós törzsoldat és eljárás előállítására
DK0497177T3 (da) Vitaminholdige formuleringer og fremstilling deraf
FR2684988B1 (fr) Procede industriel de synthese de l'acide hydroxy-10-decene-e-ouique et de l'acide oxo-9-decene-2-ouique, principe actifs de la gelee royale.
FR2674437B1 (fr) Composition pharmaceutique, utile notamment dans le traitement d'affections gastro-óoesophagiennes.
NO20010507D0 (no) Farmasöytisk sammensetning med antitumoraktivitet på basis av karboplatin
FR2657010B1 (fr) Composition pharmaceutique sous forme de suspension aqueuse stable a base de sucrafalte et d'une substance anti-acide ainsi que son procede de preparation.
MY111038A (en) An improved pesticidal aqueous suspension concentrate and a process for production thereof.
EP0393537A3 (de) Granulationsprodukt von Calciumascorbat
KR880008809A (ko) 안정화된 중아황산염 메나디온 제제 및 이들의 제조
IT8622579A0 (it) Derivati di azlattoni, processo per la loro preparazione e pesticidi contenenti questi composti come ingrediente attivo.
KR950010916A (ko) 오메프라졸의 장용성 연질캅셀제제의 제조방법

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee