AU520995B2 - 1-oxo-1h-thiazole (3,2-a) pyrimidine-2-carbaxamides and 1,3- thiazole derivatives - Google Patents

1-oxo-1h-thiazole (3,2-a) pyrimidine-2-carbaxamides and 1,3- thiazole derivatives

Info

Publication number
AU520995B2
AU520995B2 AU64595/80A AU6459580A AU520995B2 AU 520995 B2 AU520995 B2 AU 520995B2 AU 64595/80 A AU64595/80 A AU 64595/80A AU 6459580 A AU6459580 A AU 6459580A AU 520995 B2 AU520995 B2 AU 520995B2
Authority
AU
Australia
Prior art keywords
thiazole
carbaxamides
pyrimidine
oxo
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU64595/80A
Other languages
English (en)
Other versions
AU6459580A (en
Inventor
Saul Bernard Kadin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of AU6459580A publication Critical patent/AU6459580A/en
Application granted granted Critical
Publication of AU520995B2 publication Critical patent/AU520995B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/40Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AU64595/80A 1979-11-23 1980-11-21 1-oxo-1h-thiazole (3,2-a) pyrimidine-2-carbaxamides and 1,3- thiazole derivatives Ceased AU520995B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9663179A 1979-11-23 1979-11-23
US96631 1979-11-23

Publications (2)

Publication Number Publication Date
AU6459580A AU6459580A (en) 1981-05-28
AU520995B2 true AU520995B2 (en) 1982-03-11

Family

ID=22258306

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64595/80A Ceased AU520995B2 (en) 1979-11-23 1980-11-21 1-oxo-1h-thiazole (3,2-a) pyrimidine-2-carbaxamides and 1,3- thiazole derivatives

Country Status (35)

Country Link
JP (1) JPS5687586A (fr)
KR (1) KR830004322A (fr)
AR (2) AR228859A1 (fr)
AT (1) AT380883B (fr)
AU (1) AU520995B2 (fr)
BE (1) BE886319A (fr)
CA (1) CA1143731A (fr)
CH (1) CH649299A5 (fr)
CS (1) CS241476B2 (fr)
DD (1) DD154608A5 (fr)
DE (2) DE3043979C2 (fr)
DK (1) DK151811C (fr)
EG (1) EG14929A (fr)
ES (1) ES8203363A1 (fr)
FI (1) FI67706C (fr)
FR (1) FR2470132A1 (fr)
GB (1) GB2063862B (fr)
GR (1) GR72132B (fr)
GT (1) GT198066458A (fr)
HU (1) HU179091B (fr)
IE (1) IE50404B1 (fr)
IL (1) IL61535A (fr)
IN (1) IN154926B (fr)
IT (1) IT1209373B (fr)
LU (1) LU82950A1 (fr)
NL (1) NL182565C (fr)
NO (1) NO803521L (fr)
NZ (1) NZ195596A (fr)
PH (1) PH16666A (fr)
PL (1) PL132354B1 (fr)
PT (1) PT72090B (fr)
SE (1) SE448732B (fr)
SU (1) SU1042620A3 (fr)
YU (1) YU41953B (fr)
ZA (1) ZA807293B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8300728D0 (en) * 1983-01-12 1983-02-16 Erba Farmitalia Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives
US4457932A (en) * 1983-07-22 1984-07-03 Bristol-Myers Company Anti-ulcer agents
GB8422916D0 (en) * 1984-09-11 1984-10-17 May & Baker Ltd Compositions of matter
JP2690742B2 (ja) * 1987-03-30 1997-12-17 第一製薬株式会社 複素環アミン誘導体
NZ228447A (en) * 1988-03-28 1990-08-28 Janssen Pharmaceutica Nv Cosmetic or pharmaceutical composition possessing serotonin antogonistic activity
TWI500623B (zh) * 2009-10-13 2015-09-21 Torrent Pharmaceuticals Ltd 新穎稠合噻唑及噁唑嘧啶酮

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1331059A (en) 1971-04-19 1973-09-19 Lilly Industries Ltd Pyrimidotriazinone compounds
US4041163A (en) * 1976-03-29 1977-08-09 Pfizer Inc. N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents
DE2810863A1 (de) * 1978-03-13 1979-09-27 Boehringer Mannheim Gmbh 1-oxo-1h-pyrimido eckige klammer auf 6,1-b eckige klammer zu benzthiazol-derivate und verfahren zu ihrer herstellung
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones

Also Published As

Publication number Publication date
ATA570780A (de) 1985-12-15
CS782080A2 (en) 1985-06-13
NL8006362A (nl) 1981-06-16
HU179091B (en) 1982-08-28
ZA807293B (en) 1981-12-30
IN154926B (fr) 1984-12-22
NL182565B (nl) 1987-11-02
FR2470132A1 (fr) 1981-05-29
IL61535A0 (en) 1980-12-31
IE50404B1 (en) 1986-04-16
CS241476B2 (en) 1986-03-13
DK151811B (da) 1988-01-04
GB2063862B (en) 1983-06-22
DE3043979C2 (de) 1986-08-21
AT380883B (de) 1986-07-25
NO803521L (no) 1981-05-25
IE802418L (en) 1981-05-23
ES497066A0 (es) 1982-04-01
KR830004322A (ko) 1983-07-09
PH16666A (en) 1983-12-13
DK413180A (da) 1981-05-24
JPS617432B2 (fr) 1986-03-06
YU295080A (en) 1983-06-30
SE448732B (sv) 1987-03-16
AU6459580A (en) 1981-05-28
CH649299A5 (fr) 1985-05-15
PT72090B (en) 1981-09-29
AR228859A1 (es) 1983-04-29
PT72090A (en) 1980-12-01
FR2470132B1 (fr) 1983-07-29
IT1209373B (it) 1989-07-16
FI67706C (fi) 1985-05-10
FI803628L (fi) 1981-05-24
PL132354B1 (en) 1985-02-28
LU82950A1 (fr) 1981-06-04
NZ195596A (en) 1984-05-31
BE886319A (fr) 1981-05-25
GB2063862A (en) 1981-06-10
DE3050491C2 (de) 1985-10-10
SU1042620A3 (ru) 1983-09-15
SE8008189L (sv) 1981-05-24
ES8203363A1 (es) 1982-04-01
EG14929A (en) 1989-01-30
PL228008A1 (fr) 1981-12-11
IL61535A (en) 1984-06-29
DK151811C (da) 1988-06-06
GR72132B (fr) 1983-09-19
IT8026176A0 (it) 1980-11-21
NL182565C (nl) 1988-04-05
AR231296A1 (es) 1984-10-31
GT198066458A (es) 1982-05-15
CA1143731A (fr) 1983-03-29
JPS5687586A (en) 1981-07-16
DE3043979A1 (de) 1981-09-03
DD154608A5 (de) 1982-04-07
YU41953B (en) 1988-02-29
FI67706B (fi) 1985-01-31

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