AU2749502A - Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy - Google Patents

Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Info

Publication number
AU2749502A
AU2749502A AU2749502A AU2749502A AU2749502A AU 2749502 A AU2749502 A AU 2749502A AU 2749502 A AU2749502 A AU 2749502A AU 2749502 A AU2749502 A AU 2749502A AU 2749502 A AU2749502 A AU 2749502A
Authority
AU
Australia
Prior art keywords
photochemotherapy
esters
group
alkyl group
aminolevulinic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2749502A
Other languages
English (en)
Inventor
Jo Klaveness
Nils Olav Nilsen
Jon Erik Braenden
Aslak Godal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Photocure ASA
Original Assignee
Photocure ASA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Photocure ASA filed Critical Photocure ASA
Publication of AU2749502A publication Critical patent/AU2749502A/xx
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2749502A 2000-07-27 2001-07-25 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy Pending AU2749502A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0018528.0A GB0018528D0 (en) 2000-07-27 2000-07-27 Compounds
PCT/GB2001/003336 WO2002010120A1 (en) 2000-07-27 2001-07-25 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Publications (1)

Publication Number Publication Date
AU2749502A true AU2749502A (en) 2002-02-13

Family

ID=9896500

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2749502A Pending AU2749502A (en) 2000-07-27 2001-07-25 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
AU2002227495A Ceased AU2002227495B2 (en) 2000-07-27 2001-07-25 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2002227495A Ceased AU2002227495B2 (en) 2000-07-27 2001-07-25 Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

Country Status (19)

Country Link
US (2) US7217736B2 (https=)
EP (1) EP1313695B1 (https=)
JP (1) JP5010088B2 (https=)
KR (1) KR20030028554A (https=)
CN (1) CN1318388C (https=)
AT (1) ATE349417T1 (https=)
AU (2) AU2749502A (https=)
CA (1) CA2416307C (https=)
CZ (1) CZ2003260A3 (https=)
DE (1) DE60125555T2 (https=)
DK (1) DK1313695T3 (https=)
ES (1) ES2276844T3 (https=)
GB (1) GB0018528D0 (https=)
HU (1) HUP0301427A2 (https=)
NO (1) NO20030398L (https=)
NZ (1) NZ523927A (https=)
PT (1) PT1313695E (https=)
RU (1) RU2246483C2 (https=)
WO (1) WO2002010120A1 (https=)

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Also Published As

Publication number Publication date
DE60125555T2 (de) 2007-10-11
JP2004505105A (ja) 2004-02-19
PT1313695E (pt) 2007-01-31
HUP0301427A2 (hu) 2003-09-29
GB0018528D0 (en) 2000-09-13
CN1318388C (zh) 2007-05-30
NO20030398D0 (no) 2003-01-24
EP1313695B1 (en) 2006-12-27
DE60125555D1 (de) 2007-02-08
NZ523927A (en) 2004-07-30
DK1313695T3 (da) 2007-04-30
CN1460099A (zh) 2003-12-03
ATE349417T1 (de) 2007-01-15
US20040106679A1 (en) 2004-06-03
CA2416307C (en) 2013-01-22
RU2246483C2 (ru) 2005-02-20
EP1313695A1 (en) 2003-05-28
US7563819B1 (en) 2009-07-21
ES2276844T3 (es) 2007-07-01
KR20030028554A (ko) 2003-04-08
CZ2003260A3 (cs) 2003-06-18
CA2416307A1 (en) 2002-02-07
NO20030398L (no) 2003-03-12
WO2002010120A1 (en) 2002-02-07
JP5010088B2 (ja) 2012-08-29
US7217736B2 (en) 2007-05-15
AU2002227495B2 (en) 2006-01-05

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