ATE349417T1 - 5-aminolaevulinsäure-ester als mittel zur photosensibilisierung in der chemotherapie - Google Patents

5-aminolaevulinsäure-ester als mittel zur photosensibilisierung in der chemotherapie

Info

Publication number
ATE349417T1
ATE349417T1 AT01984415T AT01984415T ATE349417T1 AT E349417 T1 ATE349417 T1 AT E349417T1 AT 01984415 T AT01984415 T AT 01984415T AT 01984415 T AT01984415 T AT 01984415T AT E349417 T1 ATE349417 T1 AT E349417T1
Authority
AT
Austria
Prior art keywords
group
alkyl group
aminolaevulic
chemotherapy
acid ester
Prior art date
Application number
AT01984415T
Other languages
English (en)
Inventor
Jo Klaveness
Nils Olav Nilsen
Jon Erik Braenden
Aslak Godal
Original Assignee
Photocure Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Photocure Asa filed Critical Photocure Asa
Application granted granted Critical
Publication of ATE349417T1 publication Critical patent/ATE349417T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/00615-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
AT01984415T 2000-07-27 2001-07-25 5-aminolaevulinsäure-ester als mittel zur photosensibilisierung in der chemotherapie ATE349417T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0018528.0A GB0018528D0 (en) 2000-07-27 2000-07-27 Compounds

Publications (1)

Publication Number Publication Date
ATE349417T1 true ATE349417T1 (de) 2007-01-15

Family

ID=9896500

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01984415T ATE349417T1 (de) 2000-07-27 2001-07-25 5-aminolaevulinsäure-ester als mittel zur photosensibilisierung in der chemotherapie

Country Status (19)

Country Link
US (2) US7217736B2 (de)
EP (1) EP1313695B1 (de)
JP (1) JP5010088B2 (de)
KR (1) KR20030028554A (de)
CN (1) CN1318388C (de)
AT (1) ATE349417T1 (de)
AU (2) AU2002227495B2 (de)
CA (1) CA2416307C (de)
CZ (1) CZ2003260A3 (de)
DE (1) DE60125555T2 (de)
DK (1) DK1313695T3 (de)
ES (1) ES2276844T3 (de)
GB (1) GB0018528D0 (de)
HU (1) HUP0301427A2 (de)
NO (1) NO20030398L (de)
NZ (1) NZ523927A (de)
PT (1) PT1313695E (de)
RU (1) RU2246483C2 (de)
WO (1) WO2002010120A1 (de)

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Also Published As

Publication number Publication date
NZ523927A (en) 2004-07-30
EP1313695B1 (de) 2006-12-27
US20040106679A1 (en) 2004-06-03
KR20030028554A (ko) 2003-04-08
DK1313695T3 (da) 2007-04-30
CA2416307A1 (en) 2002-02-07
DE60125555D1 (de) 2007-02-08
EP1313695A1 (de) 2003-05-28
CA2416307C (en) 2013-01-22
CN1318388C (zh) 2007-05-30
DE60125555T2 (de) 2007-10-11
GB0018528D0 (en) 2000-09-13
JP5010088B2 (ja) 2012-08-29
US7217736B2 (en) 2007-05-15
JP2004505105A (ja) 2004-02-19
CN1460099A (zh) 2003-12-03
RU2246483C2 (ru) 2005-02-20
NO20030398D0 (no) 2003-01-24
US7563819B1 (en) 2009-07-21
AU2749502A (en) 2002-02-13
ES2276844T3 (es) 2007-07-01
WO2002010120A1 (en) 2002-02-07
HUP0301427A2 (hu) 2003-09-29
AU2002227495B2 (en) 2006-01-05
PT1313695E (pt) 2007-01-31
NO20030398L (no) 2003-03-12
CZ2003260A3 (cs) 2003-06-18

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