AU2017339517B2 - Therapeutic and diagnostic methods for cancer - Google Patents

Therapeutic and diagnostic methods for cancer Download PDF

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Publication number
AU2017339517B2
AU2017339517B2 AU2017339517A AU2017339517A AU2017339517B2 AU 2017339517 B2 AU2017339517 B2 AU 2017339517B2 AU 2017339517 A AU2017339517 A AU 2017339517A AU 2017339517 A AU2017339517 A AU 2017339517A AU 2017339517 B2 AU2017339517 B2 AU 2017339517B2
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cancer
tumor
tumor sample
individual
ttmb score
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AU2017339517A1 (en
Inventor
David Fabrizio
Garrett M. Frampton
Priti Hegde
Marcin KOWANETZ
David SHAMES
Philip J. Stephens
James Xin SUN
Roman YELENSKY
Wei Zou
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Genentech Inc
Foundation Medicine Inc
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Foundation Medicine Inc
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • A—HUMAN NECESSITIES
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    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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AU2017339517A 2016-10-06 2017-10-06 Therapeutic and diagnostic methods for cancer Active AU2017339517B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662405209P 2016-10-06 2016-10-06
US62/405,209 2016-10-06
PCT/US2017/055669 WO2018068028A1 (en) 2016-10-06 2017-10-06 Therapeutic and diagnostic methods for cancer

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AU2017339517A1 AU2017339517A1 (en) 2019-04-18
AU2017339517B2 true AU2017339517B2 (en) 2024-03-14

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US (3) US11300570B2 (enExample)
EP (1) EP3523451A1 (enExample)
JP (3) JP7579056B2 (enExample)
KR (1) KR102804118B1 (enExample)
CN (1) CN110418851A (enExample)
AU (1) AU2017339517B2 (enExample)
CA (1) CA3038712A1 (enExample)
IL (1) IL265759B2 (enExample)
MX (1) MX2019003934A (enExample)
TW (1) TWI775781B (enExample)
WO (1) WO2018068028A1 (enExample)

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