AU2011261375B2 - Glycine transporter-1 inhibitors, methods of making them, and uses thereof - Google Patents

Glycine transporter-1 inhibitors, methods of making them, and uses thereof Download PDF

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Publication number
AU2011261375B2
AU2011261375B2 AU2011261375A AU2011261375A AU2011261375B2 AU 2011261375 B2 AU2011261375 B2 AU 2011261375B2 AU 2011261375 A AU2011261375 A AU 2011261375A AU 2011261375 A AU2011261375 A AU 2011261375A AU 2011261375 B2 AU2011261375 B2 AU 2011261375B2
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methyl
piperazin
cyclohexyl
benzamide
difluoro
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AU2011261375A1 (en
Inventor
Christopher L. Cioffi
Peter R. Guzzo
Shuang Liu
Jun-Ho Maeng
Visweswaren Parthasarathy
Kashinath Sadalapure
Mark A. Wolf
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Curia Global Inc
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Albany Molecular Research Inc
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    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
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AU2011261375A 2010-06-04 2011-06-02 Glycine transporter-1 inhibitors, methods of making them, and uses thereof Expired - Fee Related AU2011261375B2 (en)

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US35166210P 2010-06-04 2010-06-04
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PCT/US2011/038939 WO2011153359A1 (en) 2010-06-04 2011-06-02 Glycine transporter-1 inhibitors, methods of making them, and uses thereof

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AU2011261375B2 true AU2011261375B2 (en) 2016-09-22

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CN (1) CN103096893B (https=)
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CA (1) CA2801074A1 (https=)
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CA2758071C (en) 2009-04-06 2018-01-09 Agios Pharmaceuticals, Inc. Pyruvate kinase m2 modulators, therapeutic compositions and related methods of use
DK2427441T3 (en) 2009-05-04 2017-03-20 Agios Pharmaceuticals Inc PKM2 Activators for use in the treatment of cancer
TWI598337B (zh) 2009-06-29 2017-09-11 阿吉歐斯製藥公司 治療化合物及組成物
ES2618630T3 (es) 2009-06-29 2017-06-21 Agios Pharmaceuticals, Inc. Composiciones terapéuticas y métodos de uso relacionados
US20130109672A1 (en) 2010-04-29 2013-05-02 The United States Of America,As Represented By The Secretary, Department Of Health And Human Service Activators of human pyruvate kinase
WO2011153359A1 (en) 2010-06-04 2011-12-08 Albany Molecular Research, Inc. Glycine transporter-1 inhibitors, methods of making them, and uses thereof
WO2012083246A1 (en) 2010-12-17 2012-06-21 Agios Pharmaceuticals, Inc. Novel n- (4- (azetidine - 1 - carbonyl) phenyl) - (hetero - ) arylsulfonamide derivatives as pyruvate kinase m2 (pmk2) modulators
ES2569712T3 (es) 2010-12-21 2016-05-12 Agios Pharmaceuticals, Inc. Activadores de PKM2 bicíclicos
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CN103096893B (zh) 2016-05-04
WO2011153359A1 (en) 2011-12-08
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NZ604035A (en) 2015-02-27
EP2575815A4 (en) 2013-12-25
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US9045445B2 (en) 2015-06-02
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