AU2009243009B2 - Potent conjugates and hydrophilic linkers - Google Patents

Potent conjugates and hydrophilic linkers Download PDF

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Publication number
AU2009243009B2
AU2009243009B2 AU2009243009A AU2009243009A AU2009243009B2 AU 2009243009 B2 AU2009243009 B2 AU 2009243009B2 AU 2009243009 A AU2009243009 A AU 2009243009A AU 2009243009 A AU2009243009 A AU 2009243009A AU 2009243009 B2 AU2009243009 B2 AU 2009243009B2
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Australia
Prior art keywords
antibody
cell
conjugate
binding agent
cells
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AU2009243009A
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AU2009243009A1 (en
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Ravi V. J. Chari
Yelena Kovtun
Rajeeva Singh
Sharon D. Wilhelm
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Immunogen Inc
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Immunogen Inc
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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