AU2007342275B2 - Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors - Google Patents
Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors Download PDFInfo
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- AU2007342275B2 AU2007342275B2 AU2007342275A AU2007342275A AU2007342275B2 AU 2007342275 B2 AU2007342275 B2 AU 2007342275B2 AU 2007342275 A AU2007342275 A AU 2007342275A AU 2007342275 A AU2007342275 A AU 2007342275A AU 2007342275 B2 AU2007342275 B2 AU 2007342275B2
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- monatin
- tryptophan
- racemase
- seq
- amino acid
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
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- Life Sciences & Earth Sciences (AREA)
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- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Indole Compounds (AREA)
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| US11/714,279 | 2007-03-06 | ||
| PCT/US2007/081932 WO2008085575A2 (en) | 2006-10-20 | 2007-10-19 | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
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| US7297800B2 (en) | 2001-12-27 | 2007-11-20 | Ajinomoto Co., Inc. | Process of producing glutamate derivatives |
| US8372989B2 (en) * | 2002-04-23 | 2013-02-12 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| US7572607B2 (en) * | 2002-04-23 | 2009-08-11 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| RU2307871C2 (ru) | 2002-08-26 | 2007-10-10 | Адзиномото Ко., Инк. | НОВАЯ АЛЬДОЛАЗА И СПОСОБ ПОЛУЧЕНИЯ ЗАМЕЩЕННЫХ α-КЕТОКИСЛОТ |
| EP2050821A3 (en) * | 2002-12-09 | 2009-05-13 | Ajinomoto Co., Inc. | Mutated D-aminotransferase and method for producing optically active glutamic acid derivatives using the same |
| KR20060061811A (ko) * | 2003-08-01 | 2006-06-08 | 카아길, 인코포레이팃드 | 모나틴 식탁용 감미제 조성물 및 이의 제조 방법 |
| EP1653810B1 (en) * | 2003-08-14 | 2007-04-25 | Cargill, Incorporated | Chewing gum compositions comprising monatin and methods of making same |
| EP1657985A1 (en) * | 2003-08-25 | 2006-05-24 | Cargill Inc. | Beverage compositions comprising monatin and methods of making same |
| ATE498691T1 (de) * | 2003-10-21 | 2011-03-15 | Cargill Inc | Herstellung von monatin und monatinvorstufen |
| JP5059746B2 (ja) * | 2005-04-20 | 2012-10-31 | カーギル，インコーポレイティド | モナチンの生体内分泌のための生成物及び方法 |
| US8158389B2 (en) * | 2005-04-20 | 2012-04-17 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
| US7582455B2 (en) * | 2005-04-26 | 2009-09-01 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| US8076108B2 (en) * | 2005-04-26 | 2011-12-13 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
| CN102690833B (zh) * | 2006-03-07 | 2015-09-09 | 巴斯夫酶有限责任公司 | 醛缩酶、编码它们的核酸及制备和使用它们的方法 |
| ES2416104T3 (es) * | 2006-03-07 | 2013-07-30 | Cargill, Incorporated | Aldolasas, ácidos nucleicos que las codifican y métodos para producir y usar las mismas |
| US20090198072A1 (en) * | 2006-05-24 | 2009-08-06 | Cargill, Incorporated | Methods and systems for increasing production of equilibrium reactions |
| AU2007267618B2 (en) * | 2006-05-24 | 2013-07-18 | Cargill, Incorporated | Methods and systems for increasing production of equilibrium reactions |
| CN101239941B (zh) * | 2007-02-08 | 2012-02-29 | 味之素株式会社 | 光学活性化合物的制造方法 |
| US8003361B2 (en) * | 2007-10-01 | 2011-08-23 | Cargill Incorporated | Production of monatin enantiomers |
| US8076107B2 (en) * | 2007-10-01 | 2011-12-13 | Cargill, Incorporated | Production of monatin stereoisomers |
| US8367847B2 (en) * | 2007-10-01 | 2013-02-05 | Cargill, Incorporated | Production of monatin enantiomers |
| WO2009088442A2 (en) * | 2008-01-03 | 2009-07-16 | Cargill, Incorporated | Isomerases and epimerases and methods of using |
| JP5683962B2 (ja) * | 2008-01-03 | 2015-03-11 | カーギル・インコーポレイテッド | アミノトランスフェラーゼおよびオキシドレダクターゼの核酸およびポリペプチドおよび使用方法 |
| WO2012050125A1 (ja) | 2010-10-14 | 2012-04-19 | 味の素株式会社 | モナティンの製造方法 |
| US8771997B2 (en) | 2011-04-20 | 2014-07-08 | Ajinomoto Co., Inc. | Method for producing monatin using an L-amino acid aminotransferase |
| WO2012147674A1 (ja) * | 2011-04-25 | 2012-11-01 | 味の素株式会社 | モナティンの製造方法 |
| ES2538720B1 (es) * | 2013-12-20 | 2016-05-12 | Universidad Autónoma de Madrid | Racemasa BsrAh para la racemización de aminoácidos |
| US11685942B2 (en) | 2016-03-04 | 2023-06-27 | President And Fellows Of Harvard College | Methods for making polypeptides including d-amino acids |
| CN106636227B (zh) * | 2016-09-22 | 2020-11-06 | 精晶药业股份有限公司 | 一种酶法转化l-丙氨酸制备丙酮酸的方法 |
| CN113025602A (zh) * | 2021-03-18 | 2021-06-25 | 绵阳晟氏健康科技有限公司 | 固定化精氨酸消旋酶及其制备方法、应用 |
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| US20050221455A1 (en) * | 2003-10-21 | 2005-10-06 | Cargill, Inc. | Production of monatin and monatin precursors |
| US20050282260A1 (en) * | 2002-04-23 | 2005-12-22 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
| WO2007133183A2 (en) * | 2006-04-26 | 2007-11-22 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
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| US3002889A (en) | 1960-06-20 | 1961-10-03 | Kyowa Hakko Kogyo Kk | Method of producing l-glutamic acid |
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Also Published As
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| AU2007342275A1 (en) | 2008-07-17 |
| US8076108B2 (en) | 2011-12-13 |
| EP2089529A2 (en) | 2009-08-19 |
| EP2089529A4 (en) | 2012-04-11 |
| WO2008085575A2 (en) | 2008-07-17 |
| WO2008085575A3 (en) | 2009-03-19 |
| EP2089529B1 (en) | 2019-03-20 |
| JP2010507367A (ja) | 2010-03-11 |
| JP2015211679A (ja) | 2015-11-26 |
| AR063348A1 (es) | 2009-01-21 |
| AU2007342275A2 (en) | 2009-07-09 |
| US20120164697A1 (en) | 2012-06-28 |
| CA2666348A1 (en) | 2008-07-17 |
| US8975046B2 (en) | 2015-03-10 |
| US20080020434A1 (en) | 2008-01-24 |
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