AU2006227571B8 - Novel anti-PlGF antibody - Google Patents

Novel anti-PlGF antibody Download PDF

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Publication number
AU2006227571B8
AU2006227571B8 AU2006227571A AU2006227571A AU2006227571B8 AU 2006227571 B8 AU2006227571 B8 AU 2006227571B8 AU 2006227571 A AU2006227571 A AU 2006227571A AU 2006227571 A AU2006227571 A AU 2006227571A AU 2006227571 B8 AU2006227571 B8 AU 2006227571B8
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AU
Australia
Prior art keywords
antigen
antibody
seq
binding
binding molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006227571A
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English (en)
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AU2006227571A1 (en
AU2006227571B2 (en
Inventor
Peter Carmeliet
Desire Collen
Jean-Marie Stassen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxurion Nv
Vlaams Instituut voor Biotechnologie VIB
Life Sciences Research Partners vzw
Original Assignee
Oxurion Nv
Life Sciences Research Partners vzw
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxurion Nv, Life Sciences Research Partners vzw filed Critical Oxurion Nv
Publication of AU2006227571A1 publication Critical patent/AU2006227571A1/en
Assigned to THROMBOGENICS N.V., VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW, LIFE SCIENCES RESEARCH PARTNERS VZW reassignment THROMBOGENICS N.V. Request for Assignment Assignors: D. COLLEN RESEARCH FOUNDATION VZW, THROMB-X N.V., VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW
Assigned to LIFE SCIENCES RESEARCH PARTNERS VZW, THROMBOGENICS N.V., VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW reassignment LIFE SCIENCES RESEARCH PARTNERS VZW Request for Assignment Assignors: D. COLLEN RESEARCH FOUNDATION VZW, THROMB-X N.V., VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW
Application granted granted Critical
Publication of AU2006227571B2 publication Critical patent/AU2006227571B2/en
Publication of AU2006227571B8 publication Critical patent/AU2006227571B8/en
Priority to AU2011201340A priority Critical patent/AU2011201340B2/en
Assigned to LIFE SCIENCES RESEARCH PARTNERS VZW, Oxurion NV, VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW reassignment LIFE SCIENCES RESEARCH PARTNERS VZW Request to Amend Deed and Register Assignors: LIFE SCIENCES RESEARCH PARTNERS VZW, THROMBOGENICS N.V., VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Endocrinology (AREA)
  • Surgery (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2006227571A 2005-03-24 2006-03-24 Novel anti-PlGF antibody Ceased AU2006227571B8 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2011201340A AU2011201340B2 (en) 2005-03-24 2011-03-23 Novel anti-PIGF antibody

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66476805P 2005-03-24 2005-03-24
US60/664,768 2005-03-24
PCT/BE2006/000023 WO2006099698A2 (en) 2005-03-24 2006-03-24 Novel anti-plgf antibody

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2011201340A Division AU2011201340B2 (en) 2005-03-24 2011-03-23 Novel anti-PIGF antibody

Publications (3)

Publication Number Publication Date
AU2006227571A1 AU2006227571A1 (en) 2006-09-28
AU2006227571B2 AU2006227571B2 (en) 2010-12-23
AU2006227571B8 true AU2006227571B8 (en) 2011-01-27

Family

ID=36928446

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2006227571A Ceased AU2006227571B8 (en) 2005-03-24 2006-03-24 Novel anti-PlGF antibody
AU2011201340A Ceased AU2011201340B2 (en) 2005-03-24 2011-03-23 Novel anti-PIGF antibody

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2011201340A Ceased AU2011201340B2 (en) 2005-03-24 2011-03-23 Novel anti-PIGF antibody

Country Status (27)

Country Link
US (3) US7875704B2 (hr)
EP (2) EP2447281B1 (hr)
JP (2) JP5164829B2 (hr)
KR (1) KR101314014B1 (hr)
CN (1) CN101184776B (hr)
AT (1) ATE549358T1 (hr)
AU (2) AU2006227571B8 (hr)
BR (1) BRPI0609151B8 (hr)
CA (1) CA2601267C (hr)
CY (1) CY1113224T1 (hr)
DK (1) DK1869085T3 (hr)
EA (1) EA013970B1 (hr)
ES (2) ES2565481T3 (hr)
HK (1) HK1116803A1 (hr)
HR (1) HRP20120477T1 (hr)
IL (1) IL185754A (hr)
ME (1) ME01446B (hr)
MX (1) MX2007011735A (hr)
NO (1) NO341877B1 (hr)
NZ (1) NZ561763A (hr)
PL (1) PL1869085T3 (hr)
PT (1) PT1869085E (hr)
RS (1) RS52372B (hr)
SI (1) SI1869085T1 (hr)
UA (1) UA94707C2 (hr)
WO (1) WO2006099698A2 (hr)
ZA (1) ZA200707258B (hr)

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WO2018187706A2 (en) * 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof
CN109134650A (zh) * 2018-09-10 2019-01-04 宁波奥丞生物科技有限公司 抗人plgf单克隆抗体的制备方法
US20220228116A1 (en) 2019-05-28 2022-07-21 Vib Vzw Cd8+ t-cells lacking plexins and their application in cancer treatment
US20220220197A1 (en) 2019-05-28 2022-07-14 Vib Vzw Cancer Treatment by Targeting Plexins in the Immune Compartment
WO2020260595A1 (en) 2019-06-26 2020-12-30 Oncurious Nv Combination treatment of medulloblastoma using a placental growth factor inhibitor and a chemotherapeutic agent
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WO2022099465A1 (zh) * 2020-11-10 2022-05-19 宁波奥丞生物科技有限公司 杂交瘤细胞株9c1、plgf-1单克隆抗体及其制备方法和应用
CN112358546B (zh) * 2020-11-10 2022-04-01 宁波奥丞生物科技有限公司 杂交瘤细胞株9c1、plgf-1单克隆抗体及其应用
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Also Published As

Publication number Publication date
DK1869085T3 (da) 2012-06-18
PT1869085E (pt) 2012-06-01
KR20080016794A (ko) 2008-02-22
US8758748B2 (en) 2014-06-24
ZA200707258B (en) 2008-06-25
BRPI0609151B1 (pt) 2020-01-21
JP2012136522A (ja) 2012-07-19
BRPI0609151A2 (pt) 2010-02-17
NO20074563L (no) 2007-12-18
AU2006227571A1 (en) 2006-09-28
JP5164829B2 (ja) 2013-03-21
NZ561763A (en) 2009-02-28
HRP20120477T1 (hr) 2012-07-31
NO341877B1 (no) 2018-02-12
US9085617B2 (en) 2015-07-21
CN101184776A (zh) 2008-05-21
SI1869085T1 (sl) 2012-07-31
BRPI0609151B8 (pt) 2021-05-25
PL1869085T3 (pl) 2012-09-28
IL185754A0 (en) 2008-01-06
ES2565481T3 (es) 2016-04-05
US20080193455A1 (en) 2008-08-14
US20140178397A1 (en) 2014-06-26
WO2006099698A2 (en) 2006-09-28
US7875704B2 (en) 2011-01-25
UA94707C2 (en) 2011-06-10
ATE549358T1 (de) 2012-03-15
CY1113224T1 (el) 2016-04-13
IL185754A (en) 2013-02-28
KR101314014B1 (ko) 2013-10-02
HK1116803A1 (en) 2009-01-02
ME01446B (me) 2013-12-20
WO2006099698A3 (en) 2006-11-30
RS52372B (en) 2012-12-31
CN101184776B (zh) 2013-04-24
EP1869085A2 (en) 2007-12-26
EP2447281A1 (en) 2012-05-02
EA200702064A1 (ru) 2008-02-28
CA2601267C (en) 2014-02-18
CA2601267A1 (en) 2006-09-28
EP2447281B1 (en) 2015-12-16
AU2011201340B2 (en) 2012-02-23
EP1869085B1 (en) 2012-03-14
JP2008532557A (ja) 2008-08-21
AU2011201340A1 (en) 2011-04-14
AU2006227571B2 (en) 2010-12-23
ES2384110T3 (es) 2012-06-29
US20110123525A1 (en) 2011-05-26
MX2007011735A (es) 2008-03-14
EA013970B1 (ru) 2010-08-30

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