AU2005225471B2 - Inhibitors of histone deacetylase - Google Patents

Inhibitors of histone deacetylase Download PDF

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Publication number
AU2005225471B2
AU2005225471B2 AU2005225471A AU2005225471A AU2005225471B2 AU 2005225471 B2 AU2005225471 B2 AU 2005225471B2 AU 2005225471 A AU2005225471 A AU 2005225471A AU 2005225471 A AU2005225471 A AU 2005225471A AU 2005225471 B2 AU2005225471 B2 AU 2005225471B2
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Prior art keywords
mmol
benzamide
phenyl
amino
hydrocarbyl
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AU2005225471A
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AU2005225471A1 (en
Inventor
Giliane Bouchain
Daniel Delorme
Sylvie Frechette
Frederic Gaudette
Ljubomir Isakovic
Silvana Leit
Oscar Moradei
Isabelle Paquin
Stephane Raeppel
Arkadii Vaisburg
Zhihong Zhou
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Methylgene Inc
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Methylgene Inc
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Priority claimed from US11/090,713 external-priority patent/US7253204B2/en
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Publication of AU2005225471B2 publication Critical patent/AU2005225471B2/en
Assigned to METHYLGENE INC. reassignment METHYLGENE INC. Request for Assignment Assignors: METHYLGENE INC.
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    • C07—ORGANIC CHEMISTRY
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    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
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    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
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AU2005225471A1 (en) 2005-10-06
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