AU2001254620A1 - Lipolytic enzyme variant - Google Patents

Lipolytic enzyme variant

Info

Publication number
AU2001254620A1
AU2001254620A1 AU2001254620A AU5462001A AU2001254620A1 AU 2001254620 A1 AU2001254620 A1 AU 2001254620A1 AU 2001254620 A AU2001254620 A AU 2001254620A AU 5462001 A AU5462001 A AU 5462001A AU 2001254620 A1 AU2001254620 A1 AU 2001254620A1
Authority
AU
Australia
Prior art keywords
altered
lipolytic enzyme
enzyme variant
amino acid
acid residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001254620A
Other languages
English (en)
Inventor
Erwin Ludo Roggen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novozymes AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26068820&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2001254620(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novozymes AS filed Critical Novozymes AS
Publication of AU2001254620A1 publication Critical patent/AU2001254620A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24—Organic nitrogen compounds
    • A21D2/26—Proteins
    • A21D2/267—Microbial proteins
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D8/00—Methods for preparing or baking dough
    • A21D8/02—Methods for preparing dough; Treating dough prior to baking
    • A21D8/04—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042—Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38645—Preparations containing enzymes, e.g. protease or amylase containing cellulase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0055—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10)
    • C12N9/0057—Oxidoreductases (1.) acting on diphenols and related substances as donors (1.10) with oxygen as acceptor (1.10.3)
    • C12N9/0061—Laccase (1.10.3.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03002—Laccase (1.10.3.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
AU2001254620A 2000-04-28 2001-04-30 Lipolytic enzyme variant Abandoned AU2001254620A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
DKPA200000707 2000-04-28
DKPA200000707 2000-04-28
US20334500P 2000-05-10 2000-05-10
US60203345 2000-05-10
DKPA200100327 2001-02-28
DKPA200100327 2001-02-28
US27781701P 2001-03-21 2001-03-21
US60277817 2001-03-21
PCT/DK2001/000286 WO2001083770A2 (fr) 2000-04-28 2001-04-30 Variant d'enzyme lipolytique

Publications (1)

Publication Number Publication Date
AU2001254620A1 true AU2001254620A1 (en) 2001-11-12

Family

ID=26068820

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2001254620A Abandoned AU2001254620A1 (en) 2000-04-28 2001-04-30 Lipolytic enzyme variant
AU2001254623A Abandoned AU2001254623A1 (en) 2000-04-28 2001-04-30 Production and use of protein variants having modified immunogenicity
AU2001254622A Abandoned AU2001254622A1 (en) 2000-04-28 2001-04-30 Laccase mutants

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2001254623A Abandoned AU2001254623A1 (en) 2000-04-28 2001-04-30 Production and use of protein variants having modified immunogenicity
AU2001254622A Abandoned AU2001254622A1 (en) 2000-04-28 2001-04-30 Laccase mutants

Country Status (8)

Country Link
US (6) US20020192792A1 (fr)
EP (7) EP2236611A1 (fr)
AT (1) ATE471377T1 (fr)
AU (3) AU2001254620A1 (fr)
CA (1) CA2406621A1 (fr)
DE (1) DE60142415D1 (fr)
ES (1) ES2588756T3 (fr)
WO (3) WO2001083761A1 (fr)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK6488D0 (da) * 1988-01-07 1988-01-07 Novo Industri As Enzymer
US6682924B1 (en) * 1995-05-05 2004-01-27 Novozymes A/S Protease variants and compositions
US20120165241A1 (en) * 1995-05-05 2012-06-28 Unilever Plc Subtilase Variants
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
ATE231186T1 (de) 1998-07-21 2003-02-15 Danisco Lebensmittel
US6686164B1 (en) * 1998-10-30 2004-02-03 Novozymes A/S Low allergenic protein variants
JP2003504046A (ja) * 1999-07-09 2003-02-04 ノボザイムス アクティーゼルスカブ グルコアミラーゼ変異体
US20020192792A1 (en) 2000-04-28 2002-12-19 Palle Schneider Laccase mutants
AU7235901A (en) 2000-07-06 2002-01-21 Novozymes As Method of preparing a dough or a baked product made from a dough, with addition of lipolytic enzymes
DK1352057T3 (da) * 2001-01-10 2009-07-20 Novozymes As Upolytisk enzymvariant
DE10121463A1 (de) * 2001-05-02 2003-02-27 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
BR0209154A (pt) 2001-05-18 2004-07-20 Danisco Processo de preparação de uma massa com uma enzima
DK200101090A (da) * 2001-07-12 2001-08-16 Novozymes As Subtilase variants
US20030119066A1 (en) * 2001-10-05 2003-06-26 Novozymes A/S Diagnostic kit for detecting immunogenic response and method of screening
DE10153792A1 (de) * 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
EP1523553B1 (fr) * 2002-01-16 2009-12-02 Genencor International, Inc. Variants de proteases a substitutions multiples
WO2003062380A2 (fr) * 2002-01-16 2003-07-31 Genencor International, Inc. Variants de protease a substitutions multiples
WO2003060112A1 (fr) 2002-01-16 2003-07-24 Novozymes A/S Variants d'enzymes lipolytiques et procede de production
CN101177675B (zh) 2002-02-08 2014-05-21 诺维信公司 肌醇六磷酸酶变体
US7511015B2 (en) * 2002-02-19 2009-03-31 The United States Of America As Represented By The Department Of Health And Human Services Modified defensins and their use
CN1668737A (zh) * 2002-05-16 2005-09-14 阿尔克-阿贝洛有限公司 重组Bet.V.1过敏原突变体及其方法和制备
US20060228791A1 (en) * 2002-06-26 2006-10-12 Novozymes A/S Subtilases and subtilase variants having altered immunogenicity
US7888093B2 (en) 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
ATE389731T1 (de) * 2002-12-12 2008-04-15 Novozymes As Verfahren zur auswahl eines lipolytischen enzyms
DE10260903A1 (de) * 2002-12-20 2004-07-08 Henkel Kgaa Neue Perhydrolasen
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
MXPA05007654A (es) 2003-01-17 2005-09-30 Danisco Metodo.
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
US7294499B2 (en) 2003-01-30 2007-11-13 Novozymes A/S Subtilases
US20060205628A1 (en) * 2003-02-18 2006-09-14 Novozymes A/S Detergent compositions
WO2004078960A1 (fr) 2003-02-26 2004-09-16 Genencor International, Inc. Amylases produisant une reaction immunogene modifiee et procedes de fabrication et d'utilisation correspondants
EP2500423B1 (fr) 2003-02-26 2015-06-17 Danisco US Inc. Amylases produisant une réponse immunogène altérée et leurs procédés de fabrication et d'utilisation
WO2004096844A2 (fr) * 2003-04-25 2004-11-11 Novozymes A/S Variants de polypeptides d'acariens du groupe 1
DK2270140T3 (en) * 2003-05-09 2016-03-14 Novozymes As Lipolytic enzyme variants
WO2004111216A2 (fr) * 2003-06-19 2004-12-23 Novozymes A/S Variantes genetiques de la phospholipase
EP1639107B1 (fr) 2003-06-19 2013-08-14 Novozymes A/S Proteases ameliorees et procedes de production de ces dernieres
WO2004111221A1 (fr) 2003-06-19 2004-12-23 Novozymes A/S Proteases
ES2358092T3 (es) 2003-10-10 2011-05-05 Novozymes A/S Variantes de proteasa.
US7718408B2 (en) 2003-12-24 2010-05-18 Danisco A/S Method
GB0716126D0 (en) 2007-08-17 2007-09-26 Danisco Process
US7906307B2 (en) 2003-12-24 2011-03-15 Danisco A/S Variant lipid acyltransferases and methods of making
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
MXPA06014649A (es) 2004-06-21 2007-03-12 Novozymes As Proteasas.
GB0416035D0 (en) * 2004-07-16 2004-08-18 Danisco Protein
DK1776455T3 (da) 2004-07-16 2015-06-22 Dupont Nutrition Biosci Aps Lipolytisk enzym, anvendelser deraf i fødevareindustrien
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
CN103224918B (zh) 2004-10-04 2015-08-26 诺维信公司 具有肌醇六磷酸酶活性的多肽和编码它的多核苷酸
WO2006042558A2 (fr) * 2004-10-22 2006-04-27 Novozymes A/S Variants de polypeptides d'acarien du groupe 2
AU2006239562B2 (en) * 2005-04-28 2010-12-23 Unilever Plc Compositions comprising tripeptides inhibiting ace
EP1874128A1 (fr) * 2005-04-28 2008-01-09 Hindustan Unilever Limited Peptides possedant un effet d'inhibition de l'enzyme de conversion de l'angiotensine
JP5113044B2 (ja) 2005-06-13 2013-01-09 ノボザイムス アクティーゼルスカブ デガミングされた脂肪酸アルキルエステルの生成
US20070161531A1 (en) 2005-07-08 2007-07-12 Novozymes A/S Subtilase variants
US20070148311A1 (en) * 2005-12-22 2007-06-28 Bunge Oils, Inc. Phytosterol esterification product and method of make same
EP2371949B1 (fr) * 2006-01-23 2017-04-19 Novozymes A/S Variantes de lipase
CA2635942A1 (fr) * 2006-01-23 2007-08-02 The Procter & Gamble Company Composition detergentes
JP2009523901A (ja) 2006-01-23 2009-06-25 ザ プロクター アンド ギャンブル カンパニー 洗剤組成物
WO2007107573A1 (fr) 2006-03-22 2007-09-27 Novozymes A/S Utilisation de polypeptides a activite antimicrobienne
BRPI0709732B1 (pt) 2006-04-04 2017-06-06 Novozymes As fitase, sequência de ácidos nucleicos isolada, construção de ácido nucleico, vetor de expressão recombinante, microrganismo recombinante, método para produzir a fitase, composição, método para melhorar o valor nutritivo de uma ração para animal, processo para reduzir os níveis de fitato no esterco de animal, método para o tratamento de proteínas de legume, e, uso da fitase ou da composição na ração para animal
EP2455462B1 (fr) * 2006-12-21 2016-03-16 Novozymes A/S Variantes de lipase pour utilisation pharmaceutique
US8221743B2 (en) 2006-12-22 2012-07-17 Novozymes A/S Use of polypeptides against diseases caused by protozoans
BRPI0720801A2 (pt) 2007-01-25 2014-09-16 Dupont Nutrition Biosci Aps Produção de um lipídio aciltranfersase a partir de células transformadas de bacillus licheniformis.
FI20075059A0 (fi) * 2007-01-29 2007-01-29 Valtion Teknillinen Allergeeniä sitovat monoklonaaliset IgE-vasta-aineet ja hypoallergeenit:tyypin l lgE:n ja allergeenin immunokompleksivuorovaikutus
US8460905B2 (en) * 2007-09-11 2013-06-11 Bunge Oils, Inc. Enzymatic degumming utilizing a mixture of PLA and PLC phospholipases with reduced reaction time
US8956853B2 (en) * 2007-01-30 2015-02-17 Bunge Oils, Inc. Enzymatic degumming utilizing a mixture of PLA and PLC phospholipases
EP2129781B1 (fr) 2007-03-26 2014-01-22 Novozymes A/S Phytase de hafnia
US8241876B2 (en) 2008-01-07 2012-08-14 Bunge Oils, Inc. Generation of triacylglycerols from gums
DK2254996T3 (da) 2008-02-29 2013-10-07 Dsm Ip Assets Bv Lipaser med høj specificitet for kortkædede fedtsyrer og anvendelser deraf
JP5647976B2 (ja) 2008-06-06 2015-01-07 ダニスコ・ユーエス・インク 変異体微生物プロテアーゼを含む組成物及び方法
EP2650364B1 (fr) 2008-09-26 2015-05-20 Novozymes A/S Variant de phytase de hafnia
EP2362902B1 (fr) * 2008-11-11 2012-10-24 Danisco US, Inc., Genencor Division Compositions et méthodes comportant une variante de subtilisine
GB0915572D0 (en) 2009-09-07 2009-10-07 Reckitt Benckiser Nv Detergent composition
BR112012006497A2 (pt) * 2009-09-25 2015-09-08 Novozymes As uso de uma variante de subtilisina, composição de lavagem de pratos, e, uso de uma composição.
CN102666824A (zh) 2009-12-21 2012-09-12 丹尼斯科美国公司 能够改进经脂肪酶处理的脂质基污渍的清洁的表面活性剂
BR112013003725B1 (pt) * 2010-08-17 2020-05-26 Council Of Scintific & Industrial Research Método para obtenção de enzima lacase a partir de arthrographis sp
MX2014007446A (es) * 2011-12-20 2014-08-01 Novozymes As Variantes de subtilasa y polinucleotidos que las codifican.
US10180434B2 (en) 2012-03-13 2019-01-15 Array Bridge Inc. Antibody array used for the analysis of the three-dimensional structure of protein therapeutics and its production
CN104736700B (zh) 2012-10-12 2019-02-01 丹尼斯科美国公司 包含脂解酶变体的组合物和方法
WO2014067933A1 (fr) 2012-10-31 2014-05-08 C-Lecta Gmbh Préparation de support bioactif pour une sécurité améliorée dans les produits de soin et les aliments
CA2923991C (fr) * 2013-10-11 2021-07-06 Mauna Kea Technologies Procede de caracterisation d'images acquises par un dispositif medical video
WO2015144936A1 (fr) * 2014-03-28 2015-10-01 Novozymes A/S Resolubilisation de cristaux de protéines à faible ph
KR101655276B1 (ko) * 2014-10-23 2016-09-08 대한민국(환경부 국립생물자원관장) 단풍잎돼지풀 추출물을 유효성분으로 함유하는 항산화 및 피부 미백용 화장료 조성물
US10781428B2 (en) 2014-12-02 2020-09-22 Novozymes A/S Laccase variants and polynucleotides encoding same
EP3234125B1 (fr) 2014-12-19 2020-04-15 Novozymes A/S Variants de protéase
WO2016097350A1 (fr) * 2014-12-19 2016-06-23 Novozymes A/S Variants de protéase et polynucléotides les codant
US11291214B2 (en) * 2015-04-06 2022-04-05 Dupont Nutrition Biosciences Aps Proteases for high protein fermented milk products
CA2995771A1 (fr) * 2015-09-25 2017-03-30 Imcyse Sa Procedes et composes ameliores pour supprimer des reponses immunitaires a des agents therapeutiques
BR112018071466A2 (pt) 2016-04-19 2019-03-19 Imcyse Sa novos peptídeos de ligação a cd1d imunogênicos
CN108239626B (zh) * 2016-12-27 2022-10-04 丰益(上海)生物技术研发中心有限公司 一种高酯化活力的脂肪酶突变体
CN109280091A (zh) * 2018-11-27 2019-01-29 苏州卫生职业技术学院 一种苦瓜多糖的生物酶提取工艺
CN109912707B (zh) * 2019-03-07 2022-03-11 辽宁师范大学 可作为肿瘤诊断标记物的七鳃鳗免疫蛋白lip突变体
CN111979208B (zh) * 2019-05-23 2023-01-10 弈柯莱生物科技(上海)股份有限公司 一种l-谷氨酸脱氢酶突变体及其应用
CN110684751B (zh) * 2019-10-23 2021-06-25 江南大学 一种催化能力提高的淀粉分支酶突变体
US20220049230A1 (en) 2020-08-13 2022-02-17 Novozymes A/S Phytase variants and polynucleotides encoding same
CN114703212B (zh) * 2022-03-01 2024-03-29 东华大学 一种运用特定区段随机突变法改造漆酶的方法及漆酶菌株lac123
WO2023225459A2 (fr) 2022-05-14 2023-11-23 Novozymes A/S Compositions et procédés de prévention, de traitement, de suppression et/ou d'élimination d'infestations et d'infections phytopathogènes

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1585105A (en) 1976-04-29 1981-02-25 Unilever Ltd Emulsions
GB1590432A (en) 1976-07-07 1981-06-03 Novo Industri As Process for the production of an enzyme granulate and the enzyme granuate thus produced
JPS57189638A (en) 1981-05-20 1982-11-22 Yakult Honsha Co Ltd Production of liquid fermented milk
DK289083A (da) 1983-06-23 1984-12-24 Novo Industri As Lipase, fremgangsmaade til fremstilling deraf og anvendelse deraf
DK263584D0 (da) 1984-05-29 1984-05-29 Novo Industri As Enzymholdige granulater anvendt som detergentadditiver
DE3423699C1 (de) 1984-06-27 1986-01-16 Maggi AG, Kempttal Saucenverbesserer in Tuben
GB8525012D0 (en) 1985-10-10 1985-11-13 Cpc International Inc Carbohydrate refining process
US4810414A (en) 1986-08-29 1989-03-07 Novo Industri A/S Enzymatic detergent additive
EP0305216B1 (fr) 1987-08-28 1995-08-02 Novo Nordisk A/S Lipase recombinante de humicola et procédé de production de lipases recombinantes de humicola
EP0319064B1 (fr) 1987-12-03 1992-05-13 Unilever N.V. Procédé de préparation d'une émulsion eau dans huile
DK6488D0 (da) * 1988-01-07 1988-01-07 Novo Industri As Enzymer
JP2709736B2 (ja) 1988-08-11 1998-02-04 昭和産業株式会社 油脂の精製方法
JP2794574B2 (ja) 1988-08-11 1998-09-10 昭和産業株式会社 リゾレシチンの製造方法
JPH02160984A (ja) 1988-12-09 1990-06-20 Novo Ind As 古紙の脱インキ方法
JPH02160997A (ja) 1988-12-13 1990-06-20 Jujo Paper Co Ltd ピッチトラブル防止法
JP2877439B2 (ja) 1989-05-17 1999-03-31 協和醗酵工業株式会社 卵の改質方法
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
DE3922748B4 (de) 1989-07-11 2006-01-05 Röhm GmbH & Co. KG Enzymatisches Weichverfahren
ATE97555T1 (de) 1989-09-29 1993-12-15 Unilever Nv Getrocknetes lyso-phospholipoprotein enthaltendes nahrungsmittel.
EP0495064B1 (fr) * 1990-08-13 2001-07-11 "BIOMAY" Produktions- und Handelsgesellschaft m.b.H. Allergene p14 au pollen de bouleau servant au diagnostic et a la therapie des maladies allergiques
AT401180B (de) * 1990-08-13 1996-07-25 Biomay Biotech Prod Für das baumpollenallergen p14 codierende rekombinante dna-moleküle, daraus hergestellte und abgeleitete polypeptide und deren verwendung
US5892013A (en) * 1990-09-13 1999-04-06 Novo Nordisk A/S Lipase variants
AU657278B2 (en) * 1990-09-13 1995-03-09 Novo Nordisk A/S Lipase variants
US5869438A (en) 1990-09-13 1999-02-09 Novo Nordisk A/S Lipase variants
JPH0687751B2 (ja) 1990-09-26 1994-11-09 辻製油株式会社 高濃度のリゾホスファチジルコリンを含むリゾレシチンを採取する方法
BR9106919A (pt) 1990-09-28 1993-08-17 Procter & Gamble Tensoativos de polihidroxi amida de acido graxo para melhorar o desempenho de enzima
DK249990D0 (da) 1990-10-17 1990-10-17 Novo Nordisk As Fremgangsmaade til enzymatisk pulpbehandling
CA2331936C (fr) * 1990-12-05 2007-07-31 Novozymes A/S Proteines a mutation d'epitopes; procede de fabrication
JPH04240286A (ja) 1991-01-25 1992-08-27 Novo Nordisk As 耐熱性リパーゼによるピッチトラブル防止法
DE4109826A1 (de) 1991-03-26 1992-11-05 Roehm Gmbh Enzymatisch unterstuetze aescher- und beizverfahren
DK0585285T3 (da) 1991-05-01 1999-05-10 Novo Nordisk As Stabiliserede enzymer
DE4115938A1 (de) 1991-05-16 1992-11-19 Metallgesellschaft Ag Enzymatisches verfahren zur verminderung des gehaltes an phosphorhaltigen bestandteilen in pflanzlichen und tierischen oelen
ATE326572T1 (de) 1991-12-20 2006-06-15 Novozymes As Entfernung von hydrophoben estern aus textilien
DK0567662T3 (da) 1992-04-25 1997-08-25 Nestle Sa Fremgangsmåde til aromatisering af en mælkechokolade
DK104592D0 (da) 1992-08-21 1992-08-21 Novo Nordisk As Fremgangsmaade
DK0628256T3 (da) 1993-06-11 1998-03-09 Nestle Sa Middel til termisk stabilisering af proteiner og produkt opnået hermed
US6436690B1 (en) * 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
DE4339556C1 (de) 1993-11-19 1995-02-02 Metallgesellschaft Ag Verfahren zum Entschleimen von Pflanzenöl mittels Enzymen
AU3741995A (en) 1994-10-26 1996-05-23 Novo Nordisk A/S Enzymatic detergent composition
GB2296011B (en) 1994-12-13 1999-06-16 Solvay Novel fusarium isolate and lipases, cutinases and enzyme compositions derived therefrom
US6475765B1 (en) * 1995-03-09 2002-11-05 Procter & Gamble Company Subtilisin DY variants having decreased adsorption and increased hydrolysis
IL117350A0 (en) * 1995-03-09 1996-07-23 Procter & Gamble Proteinase k variants having decreased adsorption and increased hydrolysis
US5837517A (en) * 1995-05-05 1998-11-17 Novo Nordisk A/S Protease variants and compositions
US6682924B1 (en) * 1995-05-05 2004-01-27 Novozymes A/S Protease variants and compositions
JP4307549B2 (ja) 1995-07-14 2009-08-05 ノボザイムス アクティーゼルスカブ 脂肪分解活性を有する修飾された酵素
JP4068142B2 (ja) 1995-08-11 2008-03-26 ノボザイムス アクティーゼルスカブ 新規の脂肪分解酵素
ZA967411B (en) * 1995-09-01 1997-04-16 Novo Nordisk Biotech Inc Blue copper oxidase mutants with enhanced activity
WO1997027276A2 (fr) 1996-01-24 1997-07-31 Novo Nordisk Biotech, Inc. Acides nucleiques codant des polypeptides presentant l'activite de la lipase d'absidia
US5804201A (en) * 1996-03-11 1998-09-08 The Rockefeller University Immunomodulatory peptides of vespid antigen 5
EP0897423B1 (fr) 1996-04-25 2004-10-13 Novozymes A/S Enzyme lipolytique alcaline
CA2254781A1 (fr) 1996-05-15 1997-11-20 The Procter & Gamble Company Compositions detergentes comprenant une enzyme lipolytique et un systeme tensio-actif specifique
JP3791058B2 (ja) 1996-07-30 2006-06-28 日本油脂株式会社 リゾレシチンの製造方法
WO1998008939A1 (fr) 1996-08-27 1998-03-05 Novo Nordisk A/S Nouvelles enzymes lipolytiques
JPH10155493A (ja) 1996-10-04 1998-06-16 Sankyo Co Ltd アスペルギルス属由来のホスホリパーゼａ１をコードする遺伝子
CN1136311C (zh) * 1996-11-04 2004-01-28 诺沃奇梅兹有限公司 枯草杆菌酶变异体和组合物
DK0869167T4 (da) 1996-12-09 2010-03-08 Novozymes As Reduktion af phosphor-indeholdende bestanddele i spiseolier; som omfatter en stor mængde ikke-hydrerbart phosphor, ved anvendelse af en phospholipase, en phospholipase fra en trådsvamp, der har en phospholipase A og/eller B aktivitet
US5998353A (en) * 1996-12-19 1999-12-07 Novo Nordisk A/S Laccase mutants
WO1998027198A1 (fr) * 1996-12-19 1998-06-25 Novo Nordisk A/S Laccases mutantes
DE19701348A1 (de) 1997-01-16 1998-07-23 Roehm Gmbh Protein mit Phospholipaseaktivität
EP1017794A1 (fr) * 1997-02-06 2000-07-12 Novo Nordisk A/S Conjugats polypeptide-polymere a groupes de fixation ajoutes et/ou retires
AU5983398A (en) * 1997-02-28 1998-09-18 Novo Nordisk A/S Laccase mutants
JP3853464B2 (ja) 1997-04-08 2006-12-06 辻製油株式会社 植物性リゾレシチンの製造法
ATE331793T1 (de) 1997-04-09 2006-07-15 Danisco Verwendung von lipase zur verbesserung von teigen und backwaren
CN1272137A (zh) * 1997-08-29 2000-11-01 诺沃挪第克公司 蛋白酶变体及组合物
CN100593036C (zh) * 1997-08-29 2010-03-03 诺沃奇梅兹有限公司 蛋白酶变体及组合物
MA25044A1 (fr) * 1997-10-23 2000-10-01 Procter & Gamble Compositions de lavage contenant des variants de proteases multisubstituees.
US6780629B2 (en) * 1997-11-21 2004-08-24 Novozymes A/S Subtilase enzymes
EP1032655B1 (fr) * 1997-11-21 2005-06-29 Novozymes A/S Variantes du type protease et compositions
US6773907B2 (en) * 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
WO1999034826A1 (fr) * 1998-01-09 1999-07-15 Circassia Limited Procedes et compositions de desensibilisation
CA2319437C (fr) * 1998-01-31 2009-06-16 University Of Arkansas Procedes et reactifs permettant de diminuer les reactions allergiques
AU3247699A (en) * 1998-02-17 1999-09-06 Novo Nordisk A/S Lipase variant
DK1062341T3 (da) * 1998-03-16 2008-11-03 Alk Abello As Muterede rekombinante allergener
US6835550B1 (en) * 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6461849B1 (en) * 1998-10-13 2002-10-08 Novozymes, A/S Modified polypeptide
US6376450B1 (en) * 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
US6686164B1 (en) * 1998-10-30 2004-02-03 Novozymes A/S Low allergenic protein variants
ES2220114T3 (es) * 1998-10-30 2004-12-01 Novozymes A/S Variantes de proteinas poco alergenicas.
NZ511340A (en) 1998-11-27 2003-07-25 Novozymes As Lipolytic enzyme variants
EP1033405A3 (fr) * 1999-02-25 2001-08-01 Ceres Incorporated Fragments d'ADN avec des séquences déterminées et polypeptides encodées par lesdits fragments
WO2001037147A2 (fr) * 1999-11-03 2001-05-25 Algonomics Nv Dispositif et procede permettant la prevision structurelle de sequences d'acides amines
US6777218B1 (en) * 2000-03-14 2004-08-17 Novozymes A/S Subtilase enzymes having an improved wash performance on egg stains
AU4981101A (en) * 2000-04-03 2001-10-15 Maxygen Inc Subtilisin variants
US20020192792A1 (en) 2000-04-28 2002-12-19 Palle Schneider Laccase mutants
US7109016B2 (en) * 2000-08-21 2006-09-19 Novozymes A/S Subtilase enzymes
US6893855B2 (en) * 2000-10-13 2005-05-17 Novozymes A/S Subtilase variants
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
EP1623029B1 (fr) * 2003-05-07 2008-09-03 Novozymes A/S Enzymes de subtilisine variant (subtilases)
US20070161531A1 (en) * 2005-07-08 2007-07-12 Novozymes A/S Subtilase variants

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WO2001083770A2 (fr) 2001-11-08
EP1555322A1 (fr) 2005-07-20
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US20110045572A1 (en) 2011-02-24
EP1280919A2 (fr) 2003-02-05
CA2406621A1 (fr) 2001-11-08
EP2236611A1 (fr) 2010-10-06
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EP2258835A1 (fr) 2010-12-08
US20030144165A1 (en) 2003-07-31
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US7226770B2 (en) 2007-06-05
EP1555322B1 (fr) 2010-06-16
US20140011259A1 (en) 2014-01-09
EP2258853B1 (fr) 2016-06-08
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US20020192792A1 (en) 2002-12-19
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AU2001254622A1 (en) 2001-11-12

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