AU2001252442B8 - Combination chemotherapy - Google Patents

Combination chemotherapy Download PDF

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Publication number
AU2001252442B8
AU2001252442B8 AU2001252442A AU2001252442A AU2001252442B8 AU 2001252442 B8 AU2001252442 B8 AU 2001252442B8 AU 2001252442 A AU2001252442 A AU 2001252442A AU 2001252442 A AU2001252442 A AU 2001252442A AU 2001252442 B8 AU2001252442 B8 AU 2001252442B8
Authority
AU
Australia
Prior art keywords
platinum
cancer
coordination compound
cancer agent
sterically hindered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001252442A
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English (en)
Other versions
AU2001252442A1 (en
AU2001252442B2 (en
Inventor
Mark Peart Smith
Trevor Charles Stephens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anormed Inc
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of AU2001252442A1 publication Critical patent/AU2001252442A1/en
Assigned to ANORMED INC. reassignment ANORMED INC. Request for Assignment Assignors: ASTRAZENECA AB
Priority to AU2006201008A priority Critical patent/AU2006201008C1/en
Application granted granted Critical
Publication of AU2001252442B2 publication Critical patent/AU2001252442B2/en
Publication of AU2001252442B8 publication Critical patent/AU2001252442B8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2001252442A 2000-05-18 2001-05-10 Combination chemotherapy Ceased AU2001252442B8 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2006201008A AU2006201008C1 (en) 2000-05-18 2006-03-09 Combination chemotherapy

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0011903.2 2000-05-18
GBGB0011903.2A GB0011903D0 (en) 2000-05-18 2000-05-18 Combination chemotherapy
PCT/GB2001/002060 WO2001087313A1 (en) 2000-05-18 2001-05-10 Combination chemotherapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2006201008A Division AU2006201008C1 (en) 2000-05-18 2006-03-09 Combination chemotherapy

Publications (3)

Publication Number Publication Date
AU2001252442A1 AU2001252442A1 (en) 2002-02-14
AU2001252442B2 AU2001252442B2 (en) 2006-03-23
AU2001252442B8 true AU2001252442B8 (en) 2006-05-04

Family

ID=9891766

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2001252442A Ceased AU2001252442B8 (en) 2000-05-18 2001-05-10 Combination chemotherapy
AU5244201A Pending AU5244201A (en) 2000-05-18 2001-05-10 Combination chemotherapy
AU2006201008A Ceased AU2006201008C1 (en) 2000-05-18 2006-03-09 Combination chemotherapy

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU5244201A Pending AU5244201A (en) 2000-05-18 2001-05-10 Combination chemotherapy
AU2006201008A Ceased AU2006201008C1 (en) 2000-05-18 2006-03-09 Combination chemotherapy

Country Status (28)

Country Link
US (1) US20040053882A1 (enExample)
EP (2) EP1283712A1 (enExample)
JP (2) JP2003533485A (enExample)
KR (2) KR20030014228A (enExample)
CN (3) CN101310719A (enExample)
AR (1) AR030281A1 (enExample)
AU (3) AU2001252442B8 (enExample)
BG (1) BG66113B1 (enExample)
BR (1) BR0110837A (enExample)
CA (1) CA2410067A1 (enExample)
CZ (1) CZ20023766A3 (enExample)
EE (1) EE05261B1 (enExample)
GB (1) GB0011903D0 (enExample)
HK (1) HK1049446A1 (enExample)
HU (1) HUP0302130A3 (enExample)
IL (1) IL151959A0 (enExample)
IS (1) IS6571A (enExample)
MX (1) MXPA02011247A (enExample)
MY (1) MY138923A (enExample)
NO (1) NO332079B1 (enExample)
NZ (1) NZ521632A (enExample)
PL (1) PL357721A1 (enExample)
RU (2) RU2429838C2 (enExample)
SK (1) SK16392002A3 (enExample)
TW (1) TW200637565A (enExample)
UA (1) UA81098C2 (enExample)
WO (1) WO2001087313A1 (enExample)
ZA (1) ZA200209279B (enExample)

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RU2273475C2 (ru) * 2004-04-06 2006-04-10 Государственное учреждение системы высшего и послевузовского профессионального образования "Сибирский государственный медицинский университет" (ГУ СВ ПО СибГМУ) Способ лечения диссеминированного колоректального рака
BRPI0613796A2 (pt) * 2005-06-07 2011-02-15 Univ Yale composicões farmacêuticas e seus usos, e métodos de tratamento de cáncer e outras condições ou estados patológicos, por meio do uso de clevudina (lfmau) e telbivudina (ldt)
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US20080045589A1 (en) * 2006-05-26 2008-02-21 Susan Kelley Drug Combinations with Substituted Diaryl Ureas for the Treatment of Cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) * 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
RU2340336C1 (ru) * 2007-05-02 2008-12-10 Государственное учреждение научно-исследовательский институт онкологии Томского Научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ онкологии ТНЦ СО РАМН) Способ комбинированного лечения немелкоклеточного рака легкого iii стадии
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
TW200920347A (en) * 2007-07-16 2009-05-16 Poniard Pharmaceuticals Inc Oral formulations for picoplatin
AU2009210654A1 (en) * 2008-02-08 2009-08-13 Poniard Pharmaceuticals, Inc. Use of picoplatin and bevacizumab to treat colorectal cancer
CN101302235B (zh) * 2008-06-30 2011-06-01 昆明贵研药业有限公司 甲啶铂的提纯
EP2598114A1 (en) * 2010-07-28 2013-06-05 Fondazione Irccs "Istituto Nazionale del Tumori" Therapeutic agent, composition including said agent, implantable device and process for the treatment of cervical cancer and/or for the prevention of the formation of neoplasms in correspondence of the cervix in a human female genital system.
KR101389072B1 (ko) * 2011-05-25 2014-04-23 가톨릭대학교 산학협력단 ＢＨＲＦ１ 발현 억제를 위한 ｓｉＲＮＡ 및 이를 포함하는 조성물
PH12018500691B1 (en) * 2015-10-05 2022-08-10 NuCana plc Combination therapy
AU2018269462B2 (en) 2017-05-16 2024-04-18 Ability Pharmaceuticals S.L. A pharmaceutical combination for the treatment of a cancer
KR20210087949A (ko) 2018-11-01 2021-07-13 알파 타우 메디컬 리미티드 종양내 알파-방출체 방사선 및 세포내 병원체에 대한 세포질 센서의 활성화
CN113694205B (zh) * 2021-09-23 2023-05-16 山东第一医科大学(山东省医学科学院) 5-ht受体抑制剂和顺铂在制备治疗肝癌的药物中的应用

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