ATE73653T1 - Polyenmakrolide enthaltende proliposomale pulver. - Google Patents
Polyenmakrolide enthaltende proliposomale pulver.Info
- Publication number
- ATE73653T1 ATE73653T1 AT88909920T AT88909920T ATE73653T1 AT E73653 T1 ATE73653 T1 AT E73653T1 AT 88909920 T AT88909920 T AT 88909920T AT 88909920 T AT88909920 T AT 88909920T AT E73653 T1 ATE73653 T1 AT E73653T1
- Authority
- AT
- Austria
- Prior art keywords
- solution
- solvent
- fine powder
- dissolved
- tertiary butanol
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Detergent Compositions (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/109,813 US4950432A (en) | 1987-10-16 | 1987-10-16 | Polyene microlide pre-liposomal powders |
PCT/US1988/003652 WO1989003208A1 (en) | 1987-10-16 | 1988-10-17 | Polyene macrolide pre-liposomal powders |
EP88909920A EP0380584B1 (de) | 1987-10-16 | 1988-10-17 | Polyenmakrolide enthaltende proliposomale pulver |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE73653T1 true ATE73653T1 (de) | 1992-04-15 |
Family
ID=22329695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88909920T ATE73653T1 (de) | 1987-10-16 | 1988-10-17 | Polyenmakrolide enthaltende proliposomale pulver. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4950432A (de) |
EP (1) | EP0380584B1 (de) |
JP (1) | JPH03500650A (de) |
AT (1) | ATE73653T1 (de) |
AU (1) | AU609565B2 (de) |
DE (1) | DE3869424D1 (de) |
WO (1) | WO1989003208A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1338736C (fr) * | 1986-12-05 | 1996-11-26 | Roger Baurain | Microcristaux comportant une substance active presentant une affinite pour les phospholipides, et au moins un phospholipide, procede de preparation |
US5830498A (en) * | 1987-10-16 | 1998-11-03 | Board Of Regents, The University Of Texas System | Liposomal-polyene preliposomal powder and method for its preparation |
US5178875A (en) * | 1991-01-14 | 1993-01-12 | The Board Of Regents, The University Of Texas System | Liposomal-polyene preliposomal powder and method for its preparation |
US4981690A (en) * | 1987-10-27 | 1991-01-01 | Board Of Regents, The University Of Texas System | Liposome-incorporated mepartricin |
AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
US5096629A (en) * | 1988-08-29 | 1992-03-17 | 501 Nippon Fine Chemical Co., Ltd. | Method for preparing lipid powder for use in preparing liposomes and method for preparing liposomes |
FR2648056A1 (fr) * | 1989-06-13 | 1990-12-14 | Ire Celltarg Sa | Procede de preparation de microparticules lipidiques d'aspect microcristallin |
FR2651680B1 (fr) * | 1989-09-14 | 1991-12-27 | Medgenix Group Sa | Nouveau procede de preparation de microparticules lipidiques. |
DE4122744C2 (de) * | 1990-08-06 | 1994-02-03 | Nattermann A & Cie | Wäßriges Liposomensystem und Verfahren zu seiner Herstellung |
US5417978A (en) * | 1993-07-29 | 1995-05-23 | Board Of Regents, The University Of Texas System | Liposomal antisense methyl phosphonate oligonucleotides and methods for their preparation and use |
US5878245A (en) * | 1993-10-29 | 1999-03-02 | Advanced Micro Devices, Inc. | High performance load/store functional unit and data cache |
US5902604A (en) * | 1995-06-06 | 1999-05-11 | Board Of Regents, The University Of Texas System | Submicron liposome suspensions obtained from preliposome lyophilizates |
US5855911A (en) * | 1995-08-29 | 1999-01-05 | Board Of Regents, The University Of Texas System | Liposomal phosphodiester, phosphorothioate, and P-ethoxy oligonucleotides |
US6977244B2 (en) * | 1996-10-04 | 2005-12-20 | Board Of Regents, The University Of Texas Systems | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
EP0975330A1 (de) * | 1997-02-04 | 2000-02-02 | Abbott Laboratories | Parenterale liposomenformulierung zur schmerzen linderung |
US7285288B1 (en) | 1997-10-03 | 2007-10-23 | Board Of Regents, The University Of Texas System | Inhibition of Bcl-2 protein expression by liposomal antisense oligodeoxynucleotides |
US7704962B1 (en) | 1997-10-03 | 2010-04-27 | Board Of Regents, The University Of Texas System | Small oligonucleotides with anti-tumor activity |
CN1489466A (zh) * | 2001-01-25 | 2004-04-14 | ����˹�ж�-����˹˹������˾ | 包含埃博霉素类似物的非肠道制剂 |
US6759058B1 (en) * | 2001-04-25 | 2004-07-06 | Western Center For Drug Development College Of Pharmacy Western University Of Health Sciences | Enteric-coated proliposomal formulations for poorly water soluble drugs |
US20030113366A1 (en) * | 2001-12-14 | 2003-06-19 | Macgregor Alexander | Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents |
JP2006500387A (ja) * | 2002-08-15 | 2006-01-05 | 雲清 劉 | 固形ナノ医薬およびその調製方法 |
ES2481167T3 (es) | 2003-08-22 | 2014-07-29 | Dupont Nutrition Biosciences Aps | Composición que comprende una bacteriocina y un extracto de una planta de la familia Labiatae |
JP2007503293A (ja) | 2003-08-22 | 2007-02-22 | ダニスコ エイ/エス | マイクロカプセル |
WO2006113679A2 (en) | 2005-04-15 | 2006-10-26 | Board Of Regents, The University Of Texas System | Delivery of sirna by neutral lipid compositions |
JP2009519250A (ja) * | 2005-12-08 | 2009-05-14 | ワイス | リポソーム組成物 |
US20070249546A1 (en) * | 2006-04-22 | 2007-10-25 | Sawaya Assad S | Ophthalmic and related aqueous solutions containing antifungal agents, uses therefor and methods for preparing them |
ES2661978T3 (es) | 2010-05-26 | 2018-04-04 | Selecta Biosciences, Inc. | Vacunas multivalentes de nanovehículos sintéticos |
EA201390660A1 (ru) | 2010-11-05 | 2013-11-29 | Селекта Байосайенсиз, Инк. | Модифицированные никотиновые соединения и связанные способы |
US9987228B2 (en) | 2014-11-18 | 2018-06-05 | National Institute For Materials Science | Method for producing porous particle |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1359473A (en) * | 1970-11-03 | 1974-07-10 | Prodotti Antibiotici Spa | Polyenic antibiotic |
US3993754A (en) * | 1974-10-09 | 1976-11-23 | The United States Of America As Represented By The United States Energy Research And Development Administration | Liposome-encapsulated actinomycin for cancer chemotherapy |
GB1523965A (en) * | 1976-03-19 | 1978-09-06 | Ici Ltd | Pharmaceutical compositions containing steroids |
GB1575343A (en) * | 1977-05-10 | 1980-09-17 | Ici Ltd | Method for preparing liposome compositions containing biologically active compounds |
CH621479A5 (de) * | 1977-08-05 | 1981-02-13 | Battelle Memorial Institute | |
US4460577A (en) * | 1977-09-30 | 1984-07-17 | Farmitalia Carlo Erba S.P.A. | Pharmaceutical compositions consisting or consisting essentially of liposomes, and processes for making same |
FR2416008A1 (fr) * | 1978-02-02 | 1979-08-31 | Oreal | Lyophilisats de liposomes |
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4529561A (en) * | 1978-03-24 | 1985-07-16 | The Regents Of The University Of California | Method for producing liposomes in selected size range |
US4186183A (en) * | 1978-03-29 | 1980-01-29 | The United States Of America As Represented By The Secretary Of The Army | Liposome carriers in chemotherapy of leishmaniasis |
IT1111367B (it) * | 1978-11-17 | 1986-01-13 | Serono Ist Farm | Processo per la preparazione estemporanea di liposomi e liposomi cosi' ottenuti |
US4241046A (en) * | 1978-11-30 | 1980-12-23 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
CA1173360A (en) * | 1979-06-22 | 1984-08-28 | Jurg Schrank | Pharmaceutical preparations |
IL64397A0 (en) * | 1981-01-07 | 1982-02-28 | Weder Hans G | Process for the preparation of liposomal medicaments |
FR2521565B1 (fr) * | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
US4515736A (en) * | 1983-05-12 | 1985-05-07 | The Regents Of The University Of California | Method for encapsulating materials into liposomes |
US4744989A (en) * | 1984-02-08 | 1988-05-17 | E. R. Squibb & Sons, Inc. | Method of preparing liposomes and products produced thereby |
US4610868A (en) * | 1984-03-20 | 1986-09-09 | The Liposome Company, Inc. | Lipid matrix carriers for use in drug delivery systems |
JPS60208910A (ja) * | 1984-03-31 | 1985-10-21 | Green Cross Corp:The | 水難溶性薬物・リン脂質複合体の製造方法 |
US4663167A (en) * | 1984-04-16 | 1987-05-05 | The Board Of Regents Of The University Of Texas System | Composition and method for treatment of disseminated fungal infections in mammals |
CA1270198A (en) * | 1984-08-08 | 1990-06-12 | Marcel B. Bally | Encapsulation of antineoplastic agents in liposomes |
JPS6176414A (ja) * | 1984-09-21 | 1986-04-18 | Shionogi & Co Ltd | リポソーム製剤の製法 |
US4622188A (en) * | 1984-12-21 | 1986-11-11 | E. I. Du Pont De Nemours And Company | Method for manufacturing liposomes |
US4830858A (en) * | 1985-02-11 | 1989-05-16 | E. R. Squibb & Sons, Inc. | Spray-drying method for preparing liposomes and products produced thereby |
US4766046A (en) * | 1985-09-27 | 1988-08-23 | Liposome Technology, Inc. | Stabilized liposome/amphotericin composition and method |
WO1987001938A1 (en) * | 1985-09-27 | 1987-04-09 | The Regents Of The University Of California | Liposome transdermal drug delivery system |
FR2593394A1 (fr) * | 1986-01-30 | 1987-07-31 | Ire Celltarg Sa | Procede de preparation de liposomes contenant une subtance active lipophile, notamment de l'amphotericine, liposomes et nouveau medicament obtenus |
US4737323A (en) * | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
FR2607403B1 (fr) * | 1986-11-28 | 1991-02-22 | Toulouse Inst Nal Sciences App | Procede et dispositif de separation d'une phase dispersee en emulsion ou en suspension dans une phase continue |
US4812312A (en) * | 1987-03-03 | 1989-03-14 | Board Of Regents Of The University Of Texas System | Liposome-incorporated nystatin |
US4863739A (en) * | 1987-05-19 | 1989-09-05 | Board Of Regents, The University Of Texas System | Liposome compositions of anthracycline derivatives |
-
1987
- 1987-10-16 US US07/109,813 patent/US4950432A/en not_active Expired - Lifetime
-
1988
- 1988-10-17 DE DE8888909920T patent/DE3869424D1/de not_active Expired - Lifetime
- 1988-10-17 EP EP88909920A patent/EP0380584B1/de not_active Expired - Lifetime
- 1988-10-17 AT AT88909920T patent/ATE73653T1/de not_active IP Right Cessation
- 1988-10-17 JP JP63509146A patent/JPH03500650A/ja active Pending
- 1988-10-17 AU AU27886/89A patent/AU609565B2/en not_active Ceased
- 1988-10-17 WO PCT/US1988/003652 patent/WO1989003208A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US4950432A (en) | 1990-08-21 |
JPH03500650A (ja) | 1991-02-14 |
EP0380584A1 (de) | 1990-08-08 |
EP0380584B1 (de) | 1992-03-18 |
AU2788689A (en) | 1989-05-02 |
AU609565B2 (en) | 1991-05-02 |
WO1989003208A1 (en) | 1989-04-20 |
DE3869424D1 (de) | 1992-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |