WO1998033482A1 - Pain reducing parenteral liposome formulation - Google Patents
Pain reducing parenteral liposome formulation Download PDFInfo
- Publication number
- WO1998033482A1 WO1998033482A1 PCT/US1998/001430 US9801430W WO9833482A1 WO 1998033482 A1 WO1998033482 A1 WO 1998033482A1 US 9801430 W US9801430 W US 9801430W WO 9833482 A1 WO9833482 A1 WO 9833482A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- formulation
- drug
- deoxy
- lipid
- group
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53298498A JP2001511780A (en) | 1997-02-04 | 1998-01-26 | Analgesic parenteral liposome formulation |
AU60414/98A AU6041498A (en) | 1997-02-04 | 1998-01-26 | Pain reducing parenteral liposome formulation |
CA002279259A CA2279259A1 (en) | 1997-02-04 | 1998-01-26 | Pain reducing parenteral liposome formulation |
EP98903718A EP0975330A1 (en) | 1997-02-04 | 1998-01-26 | Pain reducing parenteral liposome formulation |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79406497A | 1997-02-04 | 1997-02-04 | |
US360698A | 1998-01-07 | 1998-01-07 | |
US08/794,064 | 1998-01-07 | ||
US09/003,606 | 1998-01-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998033482A1 true WO1998033482A1 (en) | 1998-08-06 |
Family
ID=26671961
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/001430 WO1998033482A1 (en) | 1997-02-04 | 1998-01-26 | Pain reducing parenteral liposome formulation |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0975330A1 (en) |
JP (1) | JP2001511780A (en) |
AU (1) | AU6041498A (en) |
CA (1) | CA2279259A1 (en) |
WO (1) | WO1998033482A1 (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000078772A2 (en) * | 1999-06-19 | 2000-12-28 | The Victoria University Of Manchester | Antibiotic agents |
JP2003523938A (en) * | 1999-04-16 | 2003-08-12 | コーサン バイオサイエンシーズ, インコーポレイテッド | Macrolide anti-infectives |
US6605613B2 (en) | 1998-12-07 | 2003-08-12 | Novartis Ag | Macrolides |
US7834147B2 (en) * | 2003-04-28 | 2010-11-16 | Childrens Hospital Medical Center | Saposin C-DOPS: a novel anti-tumor agent |
CN102218034A (en) * | 2010-07-29 | 2011-10-19 | 吴赣英 | Formula, preparation method and use of azithromycin liposome combined medicament |
CN104173288A (en) * | 2014-09-03 | 2014-12-03 | 沈阳药科大学 | Clarithromycin ion pair lipidosome injection and preparation method thereof |
WO2015068397A1 (en) | 2013-11-08 | 2015-05-14 | 株式会社アクティバスファーマ | Aqueous suspension preparation comprising nanoparticles of macrolide antibacterial agent |
CN111759811A (en) * | 2020-08-06 | 2020-10-13 | 淄博职业学院 | Non-irritant clarithromycin freeze-dried powder and preparation method thereof |
EP3782627A4 (en) * | 2018-04-17 | 2021-07-07 | Shanghai Tonglian Pharmaceutical Co., Ltd. | Drug used for preventing and/or treating pain and/or fever, combination product, and use thereof |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7136777B2 (en) * | 2016-12-07 | 2022-09-13 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | new process |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3105793A (en) * | 1956-11-28 | 1963-10-01 | Lobel Mervyn Joseph | Injectable medicinal composition |
WO1987001933A1 (en) * | 1985-09-27 | 1987-04-09 | Liposome Technology, Inc. | Stabilized liposome/amphotericin composition and method |
WO1988006440A2 (en) * | 1987-03-03 | 1988-09-07 | Board Of Regents, The University Of Texas System | Liposome-incorporated nystatin |
WO1989003208A1 (en) * | 1987-10-16 | 1989-04-20 | Board Of Regents, The University Of Texas System | Polyene macrolide pre-liposomal powders |
WO1990004961A1 (en) * | 1988-11-10 | 1990-05-17 | Board Of Regents, The University Of Texas System | Liposomes incorporating aromatic polyene antibiotics |
JPH06239734A (en) * | 1993-02-18 | 1994-08-30 | Kanebo Ltd | Preparation of liposome and loposome formulation |
-
1998
- 1998-01-26 AU AU60414/98A patent/AU6041498A/en not_active Abandoned
- 1998-01-26 JP JP53298498A patent/JP2001511780A/en active Pending
- 1998-01-26 EP EP98903718A patent/EP0975330A1/en not_active Withdrawn
- 1998-01-26 CA CA002279259A patent/CA2279259A1/en not_active Abandoned
- 1998-01-26 WO PCT/US1998/001430 patent/WO1998033482A1/en not_active Application Discontinuation
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3105793A (en) * | 1956-11-28 | 1963-10-01 | Lobel Mervyn Joseph | Injectable medicinal composition |
WO1987001933A1 (en) * | 1985-09-27 | 1987-04-09 | Liposome Technology, Inc. | Stabilized liposome/amphotericin composition and method |
WO1988006440A2 (en) * | 1987-03-03 | 1988-09-07 | Board Of Regents, The University Of Texas System | Liposome-incorporated nystatin |
WO1989003208A1 (en) * | 1987-10-16 | 1989-04-20 | Board Of Regents, The University Of Texas System | Polyene macrolide pre-liposomal powders |
WO1990004961A1 (en) * | 1988-11-10 | 1990-05-17 | Board Of Regents, The University Of Texas System | Liposomes incorporating aromatic polyene antibiotics |
JPH06239734A (en) * | 1993-02-18 | 1994-08-30 | Kanebo Ltd | Preparation of liposome and loposome formulation |
Non-Patent Citations (5)
Title |
---|
CYPRIAN O. ONYEJI ET AL.: "Efficacies of liposome-encapsulated clarithromycin and ofloxacin against ...", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 38, no. 3, March 1994 (1994-03-01), pages 523 - 527, XP002065380 * |
DATABASE WPI Week 9439, Derwent World Patents Index; AN 94-313609, XP002065383 * |
L. STUHNE-SEKALEC ET AL.: "Liposomes as carrires of macrolides: preferential association of erythromycin A and azithromycin with liposomes...", JOURNAL OF MICROENCAPSULATION, vol. 8, no. 2, April 1991 (1991-04-01), LONDON, GB, pages 171 - 183, XP000216616 * |
SHYAMALA C. JAYARAMAN ET AL.: "Topical delivery of erythromycin from various formulations...", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 85, no. 10, October 1996 (1996-10-01), pages 1082 - 1084, XP002065381 * |
YU-KYOUNG OH ET AL.: "Formulation and efficacy of liposome-encapsulated antibiotics...", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 39, no. 9, September 1995 (1995-09-01), pages 2104 - 2111, XP002065382 * |
Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6605613B2 (en) | 1998-12-07 | 2003-08-12 | Novartis Ag | Macrolides |
US6852729B2 (en) | 1998-12-07 | 2005-02-08 | Novartis Ag | Macrolides |
US7297703B2 (en) | 1998-12-07 | 2007-11-20 | Novartis Ag | Macrolides |
US7572804B2 (en) | 1998-12-07 | 2009-08-11 | Novartis Ag | Macrolides |
US7741338B2 (en) | 1998-12-07 | 2010-06-22 | Novartis Ag | Macrolides |
JP2003523938A (en) * | 1999-04-16 | 2003-08-12 | コーサン バイオサイエンシーズ, インコーポレイテッド | Macrolide anti-infectives |
WO2000078772A3 (en) * | 1999-06-19 | 2002-03-21 | Univ Manchester | Antibiotic agents |
US6930092B1 (en) | 1999-06-19 | 2005-08-16 | The Victoria University Of Manchester | Antibiotic agents |
WO2000078772A2 (en) * | 1999-06-19 | 2000-12-28 | The Victoria University Of Manchester | Antibiotic agents |
US8937156B2 (en) * | 2003-04-28 | 2015-01-20 | Children's Hospital Medical Center | Saposin C-DOPS: a novel anti-tumor agent |
US7834147B2 (en) * | 2003-04-28 | 2010-11-16 | Childrens Hospital Medical Center | Saposin C-DOPS: a novel anti-tumor agent |
US10188698B2 (en) | 2003-04-28 | 2019-01-29 | Children's Hospital Medical Center | Saposin C-DOPS: a novel anti-tumor agent |
CN102218034A (en) * | 2010-07-29 | 2011-10-19 | 吴赣英 | Formula, preparation method and use of azithromycin liposome combined medicament |
WO2015068397A1 (en) | 2013-11-08 | 2015-05-14 | 株式会社アクティバスファーマ | Aqueous suspension preparation comprising nanoparticles of macrolide antibacterial agent |
CN105658203A (en) * | 2013-11-08 | 2016-06-08 | 株式会社活效制药 | Aqueous suspension preparation comprising nanoparticles of macrolide antibacterial agent |
KR20160079781A (en) | 2013-11-08 | 2016-07-06 | 액티버스 파마 컴퍼니 리미티드 | Aqueous suspension preparation comprising nanoparticles of macrolide antibacterial agent |
RU2707748C2 (en) * | 2013-11-08 | 2019-11-29 | Активус Фарма Ко., Лтд. | Composition of an aqueous suspension comprising nanoparticles of macrolide antibiotics |
US10792248B2 (en) | 2013-11-08 | 2020-10-06 | Activus Pharma Co., Ltd. | Aqueous suspension preparation comprising nanoparticles of macrolide antibacterial agent |
KR20210054068A (en) | 2013-11-08 | 2021-05-12 | 액티버스 파마 컴퍼니 리미티드 | Aqueous suspension formulation comprising nanoparticles of macrolide antibiotics |
CN104173288A (en) * | 2014-09-03 | 2014-12-03 | 沈阳药科大学 | Clarithromycin ion pair lipidosome injection and preparation method thereof |
EP3782627A4 (en) * | 2018-04-17 | 2021-07-07 | Shanghai Tonglian Pharmaceutical Co., Ltd. | Drug used for preventing and/or treating pain and/or fever, combination product, and use thereof |
CN111759811A (en) * | 2020-08-06 | 2020-10-13 | 淄博职业学院 | Non-irritant clarithromycin freeze-dried powder and preparation method thereof |
Also Published As
Publication number | Publication date |
---|---|
CA2279259A1 (en) | 1998-08-06 |
JP2001511780A (en) | 2001-08-14 |
EP0975330A1 (en) | 2000-02-02 |
AU6041498A (en) | 1998-08-25 |
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