ATE121301T1 - Mikrokristalle, die eine aktive substanz mit phospholipidischer affinität enthalten und mindestens ein phospholipid, verfahren zur herstellung. - Google Patents
Mikrokristalle, die eine aktive substanz mit phospholipidischer affinität enthalten und mindestens ein phospholipid, verfahren zur herstellung.Info
- Publication number
- ATE121301T1 ATE121301T1 AT87402747T AT87402747T ATE121301T1 AT E121301 T1 ATE121301 T1 AT E121301T1 AT 87402747 T AT87402747 T AT 87402747T AT 87402747 T AT87402747 T AT 87402747T AT E121301 T1 ATE121301 T1 AT E121301T1
- Authority
- AT
- Austria
- Prior art keywords
- phospholipid
- affinity
- phospholipidic
- producing
- active substance
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Furan Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8617116A FR2607719B1 (fr) | 1986-12-05 | 1986-12-05 | Microcristaux comportant a titre de substance active des ginkgolides et compositions pharmaceutiques les contenant |
FR8702137A FR2611138B2 (fr) | 1986-12-05 | 1987-02-19 | Microcristaux comportant une substance active presentant une affinite pour les phospholipides |
FR8712424A FR2620028B2 (fr) | 1986-12-05 | 1987-09-08 | Procede de preparation de microcristaux comportant a titre de substance active, notamment de l'amphotericine b, microcristaux obtenus et composition pharmaceutique en comprenant |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE121301T1 true ATE121301T1 (de) | 1995-05-15 |
Family
ID=27251413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT87402747T ATE121301T1 (de) | 1986-12-05 | 1987-12-03 | Mikrokristalle, die eine aktive substanz mit phospholipidischer affinität enthalten und mindestens ein phospholipid, verfahren zur herstellung. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4973465A (de) |
EP (1) | EP0270460B1 (de) |
JP (1) | JP2852421B2 (de) |
AT (1) | ATE121301T1 (de) |
CA (1) | CA1338736C (de) |
DE (1) | DE3751258T2 (de) |
ES (1) | ES2070827T3 (de) |
HK (1) | HK1007502A1 (de) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5616334A (en) * | 1987-03-05 | 1997-04-01 | The Liposome Company, Inc. | Low toxicity drug-lipid systems |
US6406713B1 (en) | 1987-03-05 | 2002-06-18 | The Liposome Company, Inc. | Methods of preparing low-toxicity drug-lipid complexes |
DE3735525C2 (de) * | 1987-10-20 | 1997-02-20 | Korth Ruth Maria | Verfahren zur Bestimmung der Wirksamkeit von paf-Acether-Rezeptor-Antagonisten |
US5174988A (en) * | 1989-07-27 | 1992-12-29 | Scientific Development & Research, Inc. | Phospholipid delivery system |
FR2651680B1 (fr) * | 1989-09-14 | 1991-12-27 | Medgenix Group Sa | Nouveau procede de preparation de microparticules lipidiques. |
US5227165A (en) * | 1989-11-13 | 1993-07-13 | Nova Pharmaceutical Corporation | Liposphere delivery systems for local anesthetics |
IE904098A1 (en) * | 1989-11-13 | 1991-05-22 | Nova Pharm Corp | Lipospheres for controlled delivery of substances |
US5188837A (en) * | 1989-11-13 | 1993-02-23 | Nova Pharmaceutical Corporation | Lipsopheres for controlled delivery of substances |
CA2068216C (en) * | 1989-11-13 | 1999-04-13 | Abraham J. Domb | Lipospheres for controlled delivery of substances |
US5221535A (en) * | 1989-11-13 | 1993-06-22 | Nova Pharmaceutical Corporation | Sustained release formulations of insect repellent |
WO1991007973A1 (fr) * | 1989-11-27 | 1991-06-13 | Nippon Shinyaku Co., Ltd. | Emulsion grasse |
US5091188A (en) * | 1990-04-26 | 1992-02-25 | Haynes Duncan H | Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs |
US5091187A (en) * | 1990-04-26 | 1992-02-25 | Haynes Duncan H | Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs |
US5336507A (en) * | 1992-12-11 | 1994-08-09 | Sterling Winthrop Inc. | Use of charged phospholipids to reduce nanoparticle aggregation |
US5785976A (en) * | 1993-03-05 | 1998-07-28 | Pharmacia & Upjohn Ab | Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof |
US5885486A (en) * | 1993-03-05 | 1999-03-23 | Pharmaciaand Upjohn Ab | Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof |
EP0706374B1 (de) * | 1993-06-30 | 1997-12-10 | Genentech, Inc. | Verfahren zur herstellung von liposomen |
ES2070778B1 (es) * | 1993-10-07 | 1995-12-16 | Vinas Lab | Composicion de liposomas y su procedimiento de obtencion. |
US5716526A (en) * | 1994-01-14 | 1998-02-10 | The Liposome Company, Inc. | Method of separating materials from liposomes or lipid complexes |
US5605785A (en) * | 1995-03-28 | 1997-02-25 | Eastman Kodak Company | Annealing processes for nanocrystallization of amorphous dispersions |
US5834025A (en) | 1995-09-29 | 1998-11-10 | Nanosystems L.L.C. | Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions |
DE69637441T2 (de) * | 1995-10-17 | 2009-03-05 | Jagotec Ag | Verabreichung unlöslicher arzneistoffe |
US7255877B2 (en) | 1996-08-22 | 2007-08-14 | Jagotec Ag | Fenofibrate microparticles |
US6465016B2 (en) | 1996-08-22 | 2002-10-15 | Research Triangle Pharmaceuticals | Cyclosporiine particles |
BRPI9810945B8 (pt) * | 1997-06-27 | 2021-05-25 | Abraxis Bioscience Inc | formulações de agentes farmacológicos, métodos para sua preparação e métodos para uso das mesmas |
CN1289091C (zh) * | 1998-02-11 | 2006-12-13 | Rtp药品公司 | 治疗炎症的药物组合物和相关用途 |
US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
AU3969099A (en) * | 1998-05-13 | 1999-11-29 | Light Sciences Limited Partnership | Controlled activation of targeted radionuclides |
CN1245955C (zh) | 1998-05-29 | 2006-03-22 | 斯凯伊药品加拿大公司 | 热保护微粒组合物及其最终蒸汽灭菌的方法 |
US6180136B1 (en) | 1998-11-10 | 2001-01-30 | Idexx Laboratories, Inc. | Phospholipid-coated microcrystals for the sustained release of pharmacologically active compounds and methods of their manufacture and use |
JP4809533B2 (ja) | 1998-11-20 | 2011-11-09 | オバン・エナジー・リミテッド | 分散し得るリン脂質で安定化されたミクロ粒子 |
US6511814B1 (en) | 1999-03-26 | 2003-01-28 | Idexx Laboratories, Inc. | Method and device for detecting analytes in fluids |
US6551842B1 (en) | 1999-03-26 | 2003-04-22 | Idexx Laboratories, Inc. | Method and device for detecting analytes in fluids |
US6602719B1 (en) | 1999-03-26 | 2003-08-05 | Idexx Laboratories, Inc. | Method and device for detecting analytes in fluids |
US6613352B2 (en) | 1999-04-13 | 2003-09-02 | Universite De Montreal | Low-rigidity liposomal formulation |
US6156294A (en) * | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
US6676930B2 (en) * | 1999-11-28 | 2004-01-13 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
AU2001257115B2 (en) | 2000-04-20 | 2005-01-27 | Rtp Pharma Inc. | Improved water-insoluble drug particle process |
US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
JP4969761B2 (ja) | 2000-08-31 | 2012-07-04 | オバン・エナジー・リミテッド | 所望粒度を持つ固体基材の小粒子および第一材料の小粒状物を含む相乗作用性混合物を製造する方法 |
US8586094B2 (en) | 2000-09-20 | 2013-11-19 | Jagotec Ag | Coated tablets |
US20030022121A1 (en) * | 2000-11-02 | 2003-01-30 | Charles Biggs | Vegetable-based compositions and articles, and methods of making same |
EP1343372A2 (de) | 2000-12-21 | 2003-09-17 | Nektar Therapeutics | Pulmonale verabreichung von polyene-antipilzmitteln |
US20050048126A1 (en) | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
US6977085B2 (en) * | 2000-12-22 | 2005-12-20 | Baxter International Inc. | Method for preparing submicron suspensions with polymorph control |
US7193084B2 (en) * | 2000-12-22 | 2007-03-20 | Baxter International Inc. | Polymorphic form of itraconazole |
US6884436B2 (en) * | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
US7037528B2 (en) * | 2000-12-22 | 2006-05-02 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
US8067032B2 (en) * | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US20040022862A1 (en) * | 2000-12-22 | 2004-02-05 | Kipp James E. | Method for preparing small particles |
US20030072807A1 (en) * | 2000-12-22 | 2003-04-17 | Wong Joseph Chung-Tak | Solid particulate antifungal compositions for pharmaceutical use |
US6951656B2 (en) * | 2000-12-22 | 2005-10-04 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
IN188924B (de) * | 2001-03-01 | 2002-11-23 | Bharat Serums & Vaccines Ltd | |
US20060003012A9 (en) * | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
MXPA04002446A (es) | 2001-09-26 | 2004-07-23 | Baxter Int | Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente. |
US7112340B2 (en) * | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
KR20060012628A (ko) * | 2003-05-19 | 2006-02-08 | 백스터 인터내셔널 인코포레이티드 | 하나 이상의 표면 변형제로 피복시킨 항경련제 또는면역억제제를 포함하는 고형 입자 |
US9044381B2 (en) * | 2003-06-24 | 2015-06-02 | Baxter International Inc. | Method for delivering drugs to the brain |
US8986736B2 (en) * | 2003-06-24 | 2015-03-24 | Baxter International Inc. | Method for delivering particulate drugs to tissues |
US20070293441A1 (en) * | 2003-09-22 | 2007-12-20 | Baxter International Inc. | High-pressure sterilization to terminally sterilize pharmaceutical preparations and medical products |
US20050169978A1 (en) * | 2004-01-29 | 2005-08-04 | Shu-Wen Fu | Wet-micro grinding |
US20050202094A1 (en) * | 2004-01-29 | 2005-09-15 | Werling Jane O. | Nanosuspensions of anti-retroviral agents for increased central nervous system delivery |
EP1711163A2 (de) * | 2004-02-05 | 2006-10-18 | Baxter International Inc. | Unter verwendung von selbststabilisierenden mitteln hergestellte dispersionen |
BRPI0510271A (pt) * | 2004-06-15 | 2007-10-30 | Baxter Int | aplicações ex-vivo agentes terapêuticos microparticulados |
JP2008512447A (ja) * | 2004-09-13 | 2008-04-24 | ブハラット セルムズ アンド ヴァクシンズ リミテッド | 防腐作用を有する静脈投与用の安定な乳剤組成物 |
US8530463B2 (en) * | 2007-05-07 | 2013-09-10 | Hale Biopharma Ventures Llc | Multimodal particulate formulations |
EP2152274A4 (de) * | 2007-05-07 | 2010-07-21 | Questor Pharmaceuticals Inc | Nasale verabreichung von benzodiazepinen |
US8722736B2 (en) | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
US8426467B2 (en) | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
GB0803969D0 (en) * | 2008-03-04 | 2008-04-09 | Britannia Pharmaceuticals Ltd | Improved phospholipid and method for its production |
CN101965195A (zh) | 2008-03-05 | 2011-02-02 | 巴克斯特国际公司 | 用于药物投送的组合物和方法 |
AU2009228093B2 (en) | 2008-03-28 | 2014-08-07 | Neurelis, Inc. | Administration of benzodiazepine compositions |
US10952965B2 (en) * | 2009-05-15 | 2021-03-23 | Baxter International Inc. | Compositions and methods for drug delivery |
PL3415139T3 (pl) | 2011-06-14 | 2022-07-11 | Neurelis, Inc. | Podawanie benzodiazepiny |
CN116687847B (zh) * | 2023-06-26 | 2024-03-29 | 石家庄四药有限公司 | 一种药物微晶注射液及其制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2664380A (en) * | 1949-11-02 | 1953-12-29 | Atomic Basic Chemicals Corp | Water-dispersible phenothiazine preparation |
DE1792410B2 (de) * | 1967-09-01 | 1980-03-13 | Apoteksvarucentralen Vitrum Apotekareaktiebolaget, Stockholm | Arzneimittelzubereitung zur intravenösen Injektion |
HU184141B (en) * | 1979-12-27 | 1984-07-30 | Human Oltoanyagtermelo | Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof |
JPS59163315A (ja) * | 1983-03-09 | 1984-09-14 | Mitsui Pharmaceut Inc | カルモフ−ル含有リポソ−ム |
JPS60208910A (ja) * | 1984-03-31 | 1985-10-21 | Green Cross Corp:The | 水難溶性薬物・リン脂質複合体の製造方法 |
US4663167A (en) * | 1984-04-16 | 1987-05-05 | The Board Of Regents Of The University Of Texas System | Composition and method for treatment of disseminated fungal infections in mammals |
JPH0647533B2 (ja) * | 1984-08-10 | 1994-06-22 | 裕 水島 | 4−ビフエニリル酢酸系化合物含有脂肪乳剤 |
US4727077A (en) * | 1985-02-20 | 1988-02-23 | Ishihara Sangyo Kaisha Ltd. | Benzoyl urea compounds, process for their production, and antitumorous compositions containing them |
US4766046A (en) * | 1985-09-27 | 1988-08-23 | Liposome Technology, Inc. | Stabilized liposome/amphotericin composition and method |
SE462894B (sv) * | 1985-10-28 | 1990-09-17 | Biogram Ab | Mikrokapslar, foerfarande foer framstaellning daerav samt anvaendning |
IE60901B1 (en) * | 1986-08-21 | 1994-08-24 | Vestar Inc | Improved treatment of systemic fungal infections with phospholipid particles encapsulating polyene antifungal antibiotics |
US4950432A (en) * | 1987-10-16 | 1990-08-21 | Board Of Regents, The University Of Texas System | Polyene microlide pre-liposomal powders |
-
1987
- 1987-12-01 CA CA000553232A patent/CA1338736C/fr not_active Expired - Lifetime
- 1987-12-03 EP EP87402747A patent/EP0270460B1/de not_active Expired - Lifetime
- 1987-12-03 AT AT87402747T patent/ATE121301T1/de not_active IP Right Cessation
- 1987-12-03 ES ES87402747T patent/ES2070827T3/es not_active Expired - Lifetime
- 1987-12-03 DE DE3751258T patent/DE3751258T2/de not_active Expired - Lifetime
- 1987-12-04 JP JP62307342A patent/JP2852421B2/ja not_active Expired - Lifetime
-
1989
- 1989-06-08 US US07/364,481 patent/US4973465A/en not_active Expired - Lifetime
-
1998
- 1998-06-25 HK HK98106755A patent/HK1007502A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1007502A1 (en) | 1999-04-16 |
DE3751258T2 (de) | 1995-09-07 |
EP0270460B1 (de) | 1995-04-19 |
US4973465A (en) | 1990-11-27 |
ES2070827T3 (es) | 1995-06-16 |
JP2852421B2 (ja) | 1999-02-03 |
EP0270460A2 (de) | 1988-06-08 |
EP0270460A3 (en) | 1990-09-05 |
JPS63208515A (ja) | 1988-08-30 |
CA1338736C (fr) | 1996-11-26 |
DE3751258D1 (de) | 1995-05-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE121301T1 (de) | Mikrokristalle, die eine aktive substanz mit phospholipidischer affinität enthalten und mindestens ein phospholipid, verfahren zur herstellung. | |
DE3779183D1 (de) | Feste pharmaceutische zubereitung mit verlaengerter wirkstofffreigabe und verfahren zur herstellung. | |
DE69002905D1 (de) | Verfahren zur Herstellung von lipidischen Mikropartikeln. | |
EP0230647A3 (en) | Method for producing a sustained release formulation | |
ATE16598T1 (de) | Verfahren zur herstellung von sulfonierten arylphosphinen. | |
ATE55542T1 (de) | Verfahren zur herstellung von liposomen. | |
DE2818655A1 (de) | Liposome | |
ES8600931A1 (es) | Un procedimiento para preparar una solucion acuosa que contiene una sustancia farmaceutica soluble en lipidos | |
DE3861985D1 (de) | Verfahren zur herstellung von trialkanolamindifettsaeureestern und deren verwendung. | |
DE3777793D1 (de) | Verfahren zur herstellung eines kolloidalen, dispersiblen systems von nanokapseln. | |
KR850003504A (ko) | 포스파티딜세린 조성물의 제조방법 및 약제 조성물 | |
DE68904483D1 (de) | Verfahren zur herstellung von kolloidalen dispergierbaren proteinsystemen, wie nanopartikeln. | |
ATE118217T1 (de) | Natrium-n-acetylneuraminat-trihydrat und verfahren zu dessen herstellung. | |
AT372965B (de) | Verfahren zur herstellung von neuen 1-oxo-1hpyrimido(6,1-b)benzthiazol-derivaten und von deren salzen | |
DE59408450D1 (de) | Wässriges Liposomensystem sowie Verfahren zur Herstellung eines derartigen Liposomensystems | |
ATE468T1 (de) | Verfahren zur herstellung von optisch aktiven, in 3-stellung substituierten 2-(2',2'-dihalogenvinyl)cyclopropan-1-carbonsaeuren und deren derivaten; 4-(2',2',2'-trihalogenaeth yl)-cyclobutan-1-sulfonsaeuresalze und deren herstellung. | |
AT346825B (de) | Verfahren zur herstellung von neuen 3- aminomethyl-2-phenylbicyclo(2,2,2)octanen und -octenen und deren saeureadditionssalzen | |
DE677381C (de) | Verfahren zur Herstellung von gegen Saeure zersetzungsbestaendigen Fixiersalzen | |
DE3683952D1 (de) | Verfahren zur herstellung einer waessrigen loesung eines heteropolysaccharides. | |
ATE42087T1 (de) | Verfahren zur herstellung von dichtem wasserfreiem natriumcarbonat und nach diesem verfahren hergestelltes dichtes wasserfreies natriumcarbonat. | |
DE59409498D1 (de) | Verfahren zur herstellung kolloidaler wässriger lösungen schwerlöslicher wirkstoffe und ein lipid dafür | |
AT373245B (de) | Verbessertes verfahren zur herstellung von hydroxymethyl-4(5)-niedrigem-alkyl-5(4)-imidazo en und deren sauren additionssalzen | |
ATA559778A (de) | Verfahren zur herstellung von neuen 1,2- -benzisothiazolen und deren saeureadditions- salzen | |
DE3762337D1 (de) | Verfahren zur herstellung von reinen hydroxylammoniumsalzen von fettsaeuren mit 1 bis 4 kohlenstoffatomen. | |
AT355572B (de) | Verfahren zur herstellung von neuen 6-(m-amino- phenyl)-2,3,5,6-tetrahydroimidazo (2,1-b)-thiazolderivaten und deren saeure- additonssalzen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EELA | Cancelled due to lapse of time |