HK1007502A1 - Microcrystals containing an active substance with a phospholipid affinity and at least one phospholipid preparation process - Google Patents

Microcrystals containing an active substance with a phospholipid affinity and at least one phospholipid preparation process

Info

Publication number
HK1007502A1
HK1007502A1 HK98106755A HK98106755A HK1007502A1 HK 1007502 A1 HK1007502 A1 HK 1007502A1 HK 98106755 A HK98106755 A HK 98106755A HK 98106755 A HK98106755 A HK 98106755A HK 1007502 A1 HK1007502 A1 HK 1007502A1
Authority
HK
Hong Kong
Prior art keywords
phospholipid
affinity
active substance
preparation process
solution
Prior art date
Application number
HK98106755A
Other languages
English (en)
Inventor
Roger Baurain
Andre Trouet
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8617116A external-priority patent/FR2607719B1/fr
Priority claimed from FR8702137A external-priority patent/FR2611138B2/fr
Priority claimed from FR8712424A external-priority patent/FR2620028B2/fr
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of HK1007502A1 publication Critical patent/HK1007502A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Furan Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Peptides Or Proteins (AREA)
HK98106755A 1986-12-05 1998-06-25 Microcrystals containing an active substance with a phospholipid affinity and at least one phospholipid preparation process HK1007502A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8617116A FR2607719B1 (fr) 1986-12-05 1986-12-05 Microcristaux comportant a titre de substance active des ginkgolides et compositions pharmaceutiques les contenant
FR8702137A FR2611138B2 (fr) 1986-12-05 1987-02-19 Microcristaux comportant une substance active presentant une affinite pour les phospholipides
FR8712424A FR2620028B2 (fr) 1986-12-05 1987-09-08 Procede de preparation de microcristaux comportant a titre de substance active, notamment de l'amphotericine b, microcristaux obtenus et composition pharmaceutique en comprenant

Publications (1)

Publication Number Publication Date
HK1007502A1 true HK1007502A1 (en) 1999-04-16

Family

ID=27251413

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98106755A HK1007502A1 (en) 1986-12-05 1998-06-25 Microcrystals containing an active substance with a phospholipid affinity and at least one phospholipid preparation process

Country Status (8)

Country Link
US (1) US4973465A (xx)
EP (1) EP0270460B1 (xx)
JP (1) JP2852421B2 (xx)
AT (1) ATE121301T1 (xx)
CA (1) CA1338736C (xx)
DE (1) DE3751258T2 (xx)
ES (1) ES2070827T3 (xx)
HK (1) HK1007502A1 (xx)

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Also Published As

Publication number Publication date
JPS63208515A (ja) 1988-08-30
DE3751258T2 (de) 1995-09-07
ATE121301T1 (de) 1995-05-15
EP0270460A3 (en) 1990-09-05
CA1338736C (fr) 1996-11-26
ES2070827T3 (es) 1995-06-16
US4973465A (en) 1990-11-27
JP2852421B2 (ja) 1999-02-03
EP0270460B1 (fr) 1995-04-19
DE3751258D1 (de) 1995-05-24
EP0270460A2 (fr) 1988-06-08

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Effective date: 20071202