US4948882A
(en)
*
|
1983-02-22 |
1990-08-14 |
Syngene, Inc. |
Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
|
JP3293820B2
(ja)
*
|
1985-12-13 |
2002-06-17 |
エンゾ− バイオケム インコ−ポレイテツド |
標的ポリヌクレオチドにハイブリツド形成するための新規な一工程方法とポリヌクレオチド化合物
|
ATE88761T1
(de)
*
|
1986-01-10 |
1993-05-15 |
Amoco Corp |
Kompetitiver homogener test.
|
US4868103A
(en)
*
|
1986-02-19 |
1989-09-19 |
Enzo Biochem, Inc. |
Analyte detection by means of energy transfer
|
DE3639109A1
(de)
*
|
1986-11-15 |
1988-05-19 |
Merck Patent Gmbh |
Verfahren zur bestimmung von nucleinsaeuren
|
EP0428000A1
(en)
*
|
1989-11-03 |
1991-05-22 |
Abbott Laboratories |
Fluorogenic substrates for the detection of proteolytic enzyme activity
|
CA2033692A1
(en)
*
|
1990-01-25 |
1991-07-26 |
Wilhelm Bannwarth |
Energy transfer systems
|
US5326692B1
(en)
*
|
1992-05-13 |
1996-04-30 |
Molecular Probes Inc |
Fluorescent microparticles with controllable enhanced stokes shift
|
US7273749B1
(en)
|
1990-06-04 |
2007-09-25 |
University Of Utah Research Foundation |
Container for carrying out and monitoring biological processes
|
US7081226B1
(en)
|
1996-06-04 |
2006-07-25 |
University Of Utah Research Foundation |
System and method for fluorescence monitoring
|
US5935522A
(en)
*
|
1990-06-04 |
1999-08-10 |
University Of Utah Research Foundation |
On-line DNA analysis system with rapid thermal cycling
|
US5210015A
(en)
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
WO1992014845A1
(en)
*
|
1991-02-26 |
1992-09-03 |
Worcester Foundation For Experimental Biology |
Diagnosing cystic fibrosis and other genetic diseases using fluorescence resonance energy transfer (fret)
|
US5578498A
(en)
|
1991-05-22 |
1996-11-26 |
Behringwerke Ag |
Metal chelate containing compositions for use in chemiluminescent assays
|
ATE246360T1
(de)
*
|
1991-05-22 |
2003-08-15 |
Dade Behring Marburg Gmbh |
Partikel, die eine zusammensetzung beinhalten, die eine chemilumineszierende verbindung umfassen
|
US6251581B1
(en)
|
1991-05-22 |
2001-06-26 |
Dade Behring Marburg Gmbh |
Assay method utilizing induced luminescence
|
US5340716A
(en)
*
|
1991-06-20 |
1994-08-23 |
Snytex (U.S.A.) Inc. |
Assay method utilizing photoactivated chemiluminescent label
|
US6652808B1
(en)
|
1991-11-07 |
2003-11-25 |
Nanotronics, Inc. |
Methods for the electronic assembly and fabrication of devices
|
JP3509859B2
(ja)
*
|
1991-11-07 |
2004-03-22 |
ナノトロニクス,インコーポレイテッド |
供与体−供与体エネルギー転移系を創製するための発色団および蛍光団でコンジュゲート化されたポリヌクレオチドのハイブリダイゼーション
|
US6569382B1
(en)
|
1991-11-07 |
2003-05-27 |
Nanogen, Inc. |
Methods apparatus for the electronic, homogeneous assembly and fabrication of devices
|
EP0653066B1
(en)
*
|
1992-07-31 |
1998-01-28 |
BEHRINGWERKE Aktiengesellschaft |
Photoactivatable chemiluminescent matrices
|
ATE319853T1
(de)
*
|
1992-11-27 |
2006-03-15 |
Canon Kk |
Verfahren und sonde zum nachweis von nukleinsäuren
|
JPH06153997A
(ja)
*
|
1992-11-27 |
1994-06-03 |
Canon Inc |
検出信号増幅による標的核酸の検出方法
|
EP0601889A2
(en)
*
|
1992-12-10 |
1994-06-15 |
Maine Medical Center Research Institute |
Nucleic acid probes
|
JP3247001B2
(ja)
*
|
1992-12-21 |
2002-01-15 |
キヤノン株式会社 |
ピリリウム化合物を用いた2本鎖核酸の検出方法、ピリリウム化合物を含有するプローブ及びそれを用いた標的核酸の検出方法、新規ピリリウム化合物
|
US5861124A
(en)
*
|
1993-07-15 |
1999-01-19 |
Hamamatsu Photonics Kk |
Method and apparatus for detecting denaturation of nucleic acid
|
WO1995003428A1
(en)
*
|
1993-07-20 |
1995-02-02 |
University Of Massachusetts Medical Center |
In vivo nucleic acid hybridization method
|
CA2126391C
(en)
*
|
1993-09-13 |
2002-01-08 |
Nobuko Yamamoto |
Determination of nucleic acid by pcr, measurement of number of microbial cells, genes, or gene-copies by pcr, and measuring-kit employed for the same
|
US5925517A
(en)
*
|
1993-11-12 |
1999-07-20 |
The Public Health Research Institute Of The City Of New York, Inc. |
Detectably labeled dual conformation oligonucleotide probes, assays and kits
|
EP1921169B1
(en)
*
|
1993-11-12 |
2012-02-15 |
PHRI Properties, Inc. |
Hybridization probes for nucleic acid detection, universal stems, methods and kits
|
US6821727B1
(en)
*
|
1993-11-15 |
2004-11-23 |
Applera Corporation |
Hybridization assay using self-quenching fluorescence probe
|
US5538848A
(en)
*
|
1994-11-16 |
1996-07-23 |
Applied Biosystems Division, Perkin-Elmer Corp. |
Method for detecting nucleic acid amplification using self-quenching fluorescence probe
|
US5824473A
(en)
*
|
1993-12-10 |
1998-10-20 |
California Institute Of Technology |
Nucleic acid mediated electron transfer
|
US5952172A
(en)
|
1993-12-10 |
1999-09-14 |
California Institute Of Technology |
Nucleic acid mediated electron transfer
|
US5591578A
(en)
*
|
1993-12-10 |
1997-01-07 |
California Institute Of Technology |
Nucleic acid mediated electron transfer
|
US6071699A
(en)
|
1996-06-07 |
2000-06-06 |
California Institute Of Technology |
Nucleic acid mediated electron transfer
|
JPH07233065A
(ja)
*
|
1993-12-27 |
1995-09-05 |
Canon Inc |
ピリリウム塩又はピリリウム類似塩を含む光化学治療薬
|
US5869255A
(en)
*
|
1994-02-01 |
1999-02-09 |
The Regents Of The University Of California |
Probes labeled with energy transfer couples dyes exemplified with DNA fragment analysis
|
US5654419A
(en)
*
|
1994-02-01 |
1997-08-05 |
The Regents Of The University Of California |
Fluorescent labels and their use in separations
|
US6028190A
(en)
|
1994-02-01 |
2000-02-22 |
The Regents Of The University Of California |
Probes labeled with energy transfer coupled dyes
|
JP3448090B2
(ja)
*
|
1994-02-16 |
2003-09-16 |
浜松ホトニクス株式会社 |
エネルギー移動検出法およびその装置
|
ATE256119T1
(de)
*
|
1994-05-26 |
2003-12-15 |
Canon Kk |
Verfahren zum nachweis von einer zielsubstanz in einer probe mit hilfe von pyryliumverbindung
|
US5620850A
(en)
|
1994-09-26 |
1997-04-15 |
President And Fellows Of Harvard College |
Molecular recognition at surfaces derivatized with self-assembled monolayers
|
AU694313B2
(en)
*
|
1995-02-17 |
1998-07-16 |
Hamamatsu Photonics K.K. |
Probe for use in nucleic acid analysis and detecting method
|
ATE196322T1
(de)
*
|
1995-05-05 |
2000-09-15 |
Perkin Elmer Corp |
Methoden and reagentien fuer die kombination einer pcr-amplifizierung mit einem hybridisierungs-assay
|
US5798276A
(en)
|
1995-06-07 |
1998-08-25 |
Molecular Probes, Inc. |
Reactive derivatives of sulforhodamine 101 with enhanced hydrolytic stability
|
US6008373A
(en)
|
1995-06-07 |
1999-12-28 |
Carnegie Mellon University |
Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
|
US5650512A
(en)
*
|
1995-06-07 |
1997-07-22 |
Systemix |
Fluorescent labeling reagents
|
IL124967A
(en)
*
|
1995-12-18 |
2000-07-26 |
Univ Washington |
Method for nucleic acid analysis using fluorescence resonance energy transfer
|
US5800996A
(en)
*
|
1996-05-03 |
1998-09-01 |
The Perkin Elmer Corporation |
Energy transfer dyes with enchanced fluorescence
|
US5863727A
(en)
*
|
1996-05-03 |
1999-01-26 |
The Perkin-Elmer Corporation |
Energy transfer dyes with enhanced fluorescence
|
US7388092B2
(en)
|
1996-05-03 |
2008-06-17 |
Applera Corporation |
Oligonucleotides and analogs labeled with energy transfer dyes
|
US5945526A
(en)
|
1996-05-03 |
1999-08-31 |
Perkin-Elmer Corporation |
Energy transfer dyes with enhanced fluorescence
|
US7825237B2
(en)
|
1996-05-03 |
2010-11-02 |
Applied Biosystems, Llc |
Oligonucleotides and analogs labeled with energy transfer dyes
|
AU726501B2
(en)
|
1996-06-04 |
2000-11-09 |
University Of Utah Research Foundation |
Monitoring hybridization during PCR
|
ES2260562T3
(es)
*
|
1996-06-04 |
2006-11-01 |
University Of Utah Research Foundation |
Sistema y metodo para llevar a cabo y supervisar procesos biologicos.
|
US6444423B1
(en)
|
1996-06-07 |
2002-09-03 |
Molecular Dynamics, Inc. |
Nucleosides comprising polydentate ligands
|
US5866336A
(en)
*
|
1996-07-16 |
1999-02-02 |
Oncor, Inc. |
Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
|
US6117635A
(en)
*
|
1996-07-16 |
2000-09-12 |
Intergen Company |
Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
|
US6582921B2
(en)
*
|
1996-07-29 |
2003-06-24 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses thereof
|
AU4321497A
(en)
*
|
1996-09-27 |
1998-04-17 |
Laboratory Of Molecular Biophotonics |
Probes for detecting polynucleotides and detection method
|
ATE230801T1
(de)
|
1996-10-03 |
2003-01-15 |
Canon Kk |
Verfahren zur detektion von zielnukleinsäure, verfahren zu ihrer quantifizierung und pyrylium- verbindungen zur chemilumineszenz-analyse
|
US5853992A
(en)
*
|
1996-10-04 |
1998-12-29 |
The Regents Of The University Of California |
Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels
|
US7381525B1
(en)
|
1997-03-07 |
2008-06-03 |
Clinical Micro Sensors, Inc. |
AC/DC voltage apparatus for detection of nucleic acids
|
US7045285B1
(en)
|
1996-11-05 |
2006-05-16 |
Clinical Micro Sensors, Inc. |
Electronic transfer moieties attached to peptide nucleic acids
|
US6096273A
(en)
|
1996-11-05 |
2000-08-01 |
Clinical Micro Sensors |
Electrodes linked via conductive oligomers to nucleic acids
|
US7160678B1
(en)
|
1996-11-05 |
2007-01-09 |
Clinical Micro Sensors, Inc. |
Compositions for the electronic detection of analytes utilizing monolayers
|
US7014992B1
(en)
*
|
1996-11-05 |
2006-03-21 |
Clinical Micro Sensors, Inc. |
Conductive oligomers attached to electrodes and nucleoside analogs
|
US6706473B1
(en)
|
1996-12-06 |
2004-03-16 |
Nanogen, Inc. |
Systems and devices for photoelectrophoretic transport and hybridization of oligonucleotides
|
US6180347B1
(en)
*
|
1997-02-03 |
2001-01-30 |
Laboratory Of Molecular Biophotonics |
Method for monitoring transcriptional synthesis of RNA
|
GB9707996D0
(en)
*
|
1997-04-21 |
1997-06-11 |
Univ Cambridge Tech |
Screening
|
US6165800A
(en)
*
|
1997-05-30 |
2000-12-26 |
Bayer Corporation |
Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
|
US6013459A
(en)
*
|
1997-06-12 |
2000-01-11 |
Clinical Micro Sensors, Inc. |
Detection of analytes using reorganization energy
|
JPH1189598A
(ja)
*
|
1997-09-18 |
1999-04-06 |
Hitachi Software Eng Co Ltd |
蛍光標識プローブ及びハイブリダイゼーション検出方法
|
US6686150B1
(en)
|
1998-01-27 |
2004-02-03 |
Clinical Micro Sensors, Inc. |
Amplification of nucleic acids with electronic detection
|
JP2002500897A
(ja)
|
1998-01-27 |
2002-01-15 |
クリニカル・マイクロ・センサーズ・インコーポレイテッド |
電子的核酸検出の増幅
|
US6713256B1
(en)
|
1998-02-14 |
2004-03-30 |
Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. |
Fluorescent energy transfer mediated chemical activation (fetma) for the elucidation of the three-dimensional structure of biomacromolecules
|
US6468743B1
(en)
*
|
1998-05-18 |
2002-10-22 |
Conagra Grocery Products Company |
PCR techniques for detecting microbial contaminants in foodstuffs
|
GB9812768D0
(en)
|
1998-06-13 |
1998-08-12 |
Zeneca Ltd |
Methods
|
US6290839B1
(en)
|
1998-06-23 |
2001-09-18 |
Clinical Micro Sensors, Inc. |
Systems for electrophoretic transport and detection of analytes
|
US6761816B1
(en)
|
1998-06-23 |
2004-07-13 |
Clinical Micro Systems, Inc. |
Printed circuit boards with monolayers and capture ligands
|
ATE440963T1
(de)
|
1998-07-02 |
2009-09-15 |
Gen Probe Inc |
Molekulare fackeln
|
US6288221B1
(en)
|
1998-08-20 |
2001-09-11 |
Duke University |
Methods of synthesis of halogen base-modified oligonucleotides and subsequent labeling with a metal-catalyzed reaction
|
US6740518B1
(en)
|
1998-09-17 |
2004-05-25 |
Clinical Micro Sensors, Inc. |
Signal detection techniques for the detection of analytes
|
US6541617B1
(en)
|
1998-10-27 |
2003-04-01 |
Clinical Micro Sensors, Inc. |
Detection of target analytes using particles and electrodes
|
DE19850593A1
(de)
*
|
1998-11-03 |
2000-05-04 |
Biochip Technologies Gmbh |
Verfahren zum Nachweis von Hybridisierungsereignissen bei DNA
|
US6833267B1
(en)
|
1998-12-30 |
2004-12-21 |
Clinical Micro Sensors, Inc. |
Tissue collection devices containing biosensors
|
US6573047B1
(en)
|
1999-04-13 |
2003-06-03 |
Dna Sciences, Inc. |
Detection of nucleotide sequence variation through fluorescence resonance energy transfer label generation
|
US6942771B1
(en)
|
1999-04-21 |
2005-09-13 |
Clinical Micro Sensors, Inc. |
Microfluidic systems in the electrochemical detection of target analytes
|
US6642001B1
(en)
|
1999-07-13 |
2003-11-04 |
Whitehead Institute For Biomedical Research |
Generic SBE-FRET protocol
|
CA2380258C
(en)
|
1999-07-26 |
2008-07-15 |
Clinical Micro Sensors, Inc. |
Sequence determination of nucleic acids using electronic detection
|
US6358684B1
(en)
|
1999-08-27 |
2002-03-19 |
Pe Corporation |
UV excitable fluorescent energy transfer dyes
|
US6218124B1
(en)
|
1999-08-27 |
2001-04-17 |
Pe Corporation |
Method for detecting oligonucleotides using UV light source
|
IL149676A0
(en)
|
1999-12-02 |
2002-11-10 |
Dna Sciences Inc |
Methods and kits for determining nucleotide variations
|
US6753143B2
(en)
|
2000-05-01 |
2004-06-22 |
Clinical Micro Sensors, Inc. |
Target analyte detection using asymmetrical self-assembled monolayers
|
US6355433B1
(en)
|
2000-06-02 |
2002-03-12 |
Dna Sciences, Inc. |
Determination of nucleotide sequence variations through limited primer extension
|
CN1348096A
(zh)
|
2000-10-10 |
2002-05-08 |
栾国彦 |
一种均相特异性检测核酸的探针及应用方法
|
US7081336B2
(en)
*
|
2001-06-25 |
2006-07-25 |
Georgia Tech Research Corporation |
Dual resonance energy transfer nucleic acid probes
|
DE10132211A1
(de)
*
|
2001-06-27 |
2003-01-16 |
Epigenomics Ag |
Nachweis spezifischer Dinukleotide in DNA-Proben durch Fluoreszenzresonanzenergietransfer (FRET)
|
AU2003226829A1
(en)
*
|
2002-02-11 |
2003-09-04 |
Applied Research Systems Ars Holding N.V. |
Nucleotide detection by fluorescence resonance energy transfer and methods thereof
|
JP3917640B2
(ja)
*
|
2002-07-26 |
2007-05-23 |
株式会社東芝 |
核酸プローブ固定化基体を用いた標的核酸の存在を検出する方法
|
EP1389638A1
(en)
*
|
2002-08-06 |
2004-02-18 |
Roche Diagnostics GmbH |
Improved fluorescent resonance energy transfer probes
|
EP1403382A3
(en)
*
|
2002-08-06 |
2004-05-06 |
Roche Diagnostics GmbH |
Improved fluorescent resonance energy transfer probes
|
EP1405920A3
(en)
*
|
2002-10-02 |
2004-04-14 |
Roche Diagnostics GmbH |
Improved FRET process
|
EP1585832B1
(en)
*
|
2002-12-20 |
2008-02-13 |
Stratagene |
Compositions and methods for polynucleotide detection
|
GB0311948D0
(en)
*
|
2003-05-23 |
2003-06-25 |
Stockport Innovation Ltd |
Light emitting probes
|
US8034554B2
(en)
|
2004-07-01 |
2011-10-11 |
Gen-Probe Incorporated |
Methods and compositions to detect nucleic acids in a biological sample
|
US8354523B2
(en)
|
2006-07-19 |
2013-01-15 |
Allelogic Biosciences Corporation |
Oligonucleotide probes and uses thereof
|
JP5709104B2
(ja)
*
|
2008-07-01 |
2015-04-30 |
国立大学法人名古屋大学 |
オリゴヌクレオチドプローブ及びその利用
|
WO2010068473A1
(en)
|
2008-11-25 |
2010-06-17 |
Gen-Probe Incorporated |
Compositions and methods for detecting small rnas, and uses thereof
|