ATE539079T1 - Imidazochinoxalinverbindungen als immunmodulatoren - Google Patents

Imidazochinoxalinverbindungen als immunmodulatoren

Info

Publication number
ATE539079T1
ATE539079T1 AT07759315T AT07759315T ATE539079T1 AT E539079 T1 ATE539079 T1 AT E539079T1 AT 07759315 T AT07759315 T AT 07759315T AT 07759315 T AT07759315 T AT 07759315T AT E539079 T1 ATE539079 T1 AT E539079T1
Authority
AT
Austria
Prior art keywords
compounds
imidazochinoxaline
compositions
immune modulators
administering
Prior art date
Application number
AT07759315T
Other languages
English (en)
Inventor
James Sutton
Feng Xu
Nicholas Valiante
Jiong Lan
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE539079T1 publication Critical patent/ATE539079T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/21—Retroviridae, e.g. equine infectious anemia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT07759315T 2006-03-23 2007-03-23 Imidazochinoxalinverbindungen als immunmodulatoren ATE539079T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78554506P 2006-03-23 2006-03-23
PCT/US2007/064858 WO2007109813A1 (en) 2006-03-23 2007-03-23 Imidazoquinoxaline compounds as immunomodulators

Publications (1)

Publication Number Publication Date
ATE539079T1 true ATE539079T1 (de) 2012-01-15

Family

ID=38191164

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07759315T ATE539079T1 (de) 2006-03-23 2007-03-23 Imidazochinoxalinverbindungen als immunmodulatoren

Country Status (6)

Country Link
US (2) US8173657B2 (de)
EP (2) EP2357184B1 (de)
AT (1) ATE539079T1 (de)
CA (1) CA2646539A1 (de)
ES (2) ES2536426T3 (de)
WO (1) WO2007109813A1 (de)

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US20090311288A1 (en) 2009-12-17
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CA2646539A1 (en) 2007-09-27
ES2376492T3 (es) 2012-03-14
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US20130101622A1 (en) 2013-04-25

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