ATE498019T1 - Verfahren zur quantifizierung von cholesterin in kleinem dichtem low-density-lipoprotein - Google Patents
Verfahren zur quantifizierung von cholesterin in kleinem dichtem low-density-lipoproteinInfo
- Publication number
- ATE498019T1 ATE498019T1 AT07829906T AT07829906T ATE498019T1 AT E498019 T1 ATE498019 T1 AT E498019T1 AT 07829906 T AT07829906 T AT 07829906T AT 07829906 T AT07829906 T AT 07829906T AT E498019 T1 ATE498019 T1 AT E498019T1
- Authority
- AT
- Austria
- Prior art keywords
- sdldl
- sample
- cholesterol
- reaction
- density lipoprotein
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 6
- 235000012000 cholesterol Nutrition 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000007330 LDL Lipoproteins Human genes 0.000 title 1
- 108010007622 LDL Lipoproteins Proteins 0.000 title 1
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 4
- 238000005259 measurement Methods 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 239000005515 coenzyme Substances 0.000 abstract 2
- 108010023302 HDL Cholesterol Proteins 0.000 abstract 1
- 102000000019 Sterol Esterase Human genes 0.000 abstract 1
- 108010055297 Sterol Esterase Proteins 0.000 abstract 1
- 238000011088 calibration curve Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006283418 | 2006-10-18 | ||
| PCT/JP2007/070172 WO2008050636A1 (fr) | 2006-10-18 | 2007-10-16 | Procédé de quantification du cholestérol dans une lipoprotéine de faible densité |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE498019T1 true ATE498019T1 (de) | 2011-02-15 |
Family
ID=39324435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07829906T ATE498019T1 (de) | 2006-10-18 | 2007-10-16 | Verfahren zur quantifizierung von cholesterin in kleinem dichtem low-density-lipoprotein |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8163512B2 (de) |
| EP (1) | EP2077333B1 (de) |
| JP (1) | JP5111389B2 (de) |
| KR (1) | KR101467926B1 (de) |
| CN (2) | CN103305592A (de) |
| AT (1) | ATE498019T1 (de) |
| DE (1) | DE602007012455D1 (de) |
| TW (1) | TWI421058B (de) |
| WO (1) | WO2008050636A1 (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5081814B2 (ja) * | 2006-05-01 | 2012-11-28 | デンカ生研株式会社 | 家族性複合型高脂血症の検出方法 |
| JP5325093B2 (ja) * | 2007-02-28 | 2013-10-23 | デンカ生研株式会社 | 小粒子低比重リポ蛋白の定量試薬 |
| WO2009048143A1 (ja) | 2007-10-10 | 2009-04-16 | Denka Seiken Co., Ltd. | small,dense LDLコレステロールの定量方法およびキット |
| JP5285000B2 (ja) * | 2010-02-23 | 2013-09-11 | 富士フイルム株式会社 | 低密度リポ蛋白コレステロールの測定方法 |
| JP5832995B2 (ja) * | 2010-04-30 | 2015-12-16 | 協和メデックス株式会社 | 低密度リポ蛋白中のコレステロールの測定方法、測定用試薬及び測定用キット |
| US20140147869A1 (en) * | 2010-10-29 | 2014-05-29 | Arkray, Inc. | Method and Kit for Measuring Cholesterol in Low-Density Lipoproteins |
| JP6047778B2 (ja) * | 2012-01-12 | 2016-12-21 | 株式会社シノテスト | 測定対象物質の測定方法及び測定試薬、並びにビリルビンに由来する影響の回避方法 |
| CN104673879A (zh) * | 2015-03-07 | 2015-06-03 | 王贤俊 | 一种小而密低密度脂蛋白胆固醇检测试剂盒及其制备 |
| CN105385751B (zh) * | 2015-12-24 | 2019-10-15 | 山东博科生物产业有限公司 | 一种准确度高、抗干扰能力强的总胆固醇检测试剂 |
| CN105652021B (zh) * | 2016-03-11 | 2018-01-02 | 上海练佰生物技术中心 | 一种测定小而密脂蛋白的试剂、方法和试剂盒 |
| JP6829009B2 (ja) * | 2016-05-24 | 2021-02-10 | デンカ株式会社 | トリグリセリドリッチリポ蛋白中のコレステロールの定量方法及び定量試薬 |
| CN107446989B (zh) * | 2017-06-23 | 2020-07-14 | 美康生物科技股份有限公司 | 测定样本中的小而密低密度脂蛋白胆固醇的方法及试剂 |
| CN107505272B (zh) * | 2017-08-10 | 2020-09-25 | 东软威特曼生物科技(南京)有限公司 | 低密度脂蛋白胆固醇检测试剂盒及其使用方法 |
| CA3073816A1 (en) * | 2017-09-01 | 2019-03-07 | Hitachi Chemical Diagnostics Systems Co., Ltd. | Method for measuring cholesterol in low-density lipoprotein, measurement reagent, and measurement kit |
| CN110736846B (zh) * | 2018-07-20 | 2023-07-14 | 上海微鸿企业管理有限公司 | 一种小而密脂蛋白的测定试剂、方法和试剂盒 |
| JP6426873B1 (ja) * | 2018-08-06 | 2018-11-21 | 積水メディカル株式会社 | マイコプラズマ・ニューモニエの免疫学的検出方法 |
| JP2020030147A (ja) * | 2018-08-23 | 2020-02-27 | デンカ生研株式会社 | 原発性胆汁性胆管炎の検出を補助する方法 |
| CN111690715A (zh) * | 2019-03-12 | 2020-09-22 | 程明 | 一种小而密低密度脂蛋白胆固醇测定试剂盒及其测定方法 |
| JP6703175B1 (ja) | 2019-09-10 | 2020-06-03 | デンカ生研株式会社 | キットおよび方法 |
| CN110564810A (zh) * | 2019-09-19 | 2019-12-13 | 武汉瀚海新酶生物科技有限公司 | 一种高性能小而密低密度脂蛋白胆固醇检测试剂盒 |
| CN110791549B (zh) * | 2019-12-03 | 2023-09-26 | 宁波普瑞柏生物技术股份有限公司 | 定量测定小而密低密度脂蛋白胆固醇的方法和试剂盒 |
| CN111269962B (zh) * | 2020-03-18 | 2021-03-23 | 浙江夸克生物科技有限公司 | 一种小而密低密度脂蛋白胆固醇测定试剂盒及其应用 |
| CN113495069B (zh) * | 2021-04-19 | 2024-04-26 | 深圳市锦瑞生物科技股份有限公司 | 一种总胆固醇检测试剂及检测芯片 |
| WO2023049473A1 (en) * | 2021-09-27 | 2023-03-30 | Icahn School Of Medicine At Mount Sinai | System and method to determine the concentration of lipoprotein (a) cholesterol |
| CN114350744B (zh) * | 2022-01-21 | 2023-03-24 | 广西康柏莱科技有限公司 | 一种小而密低密度脂蛋白胆固醇检测试剂盒 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2344055C (en) | 1998-09-18 | 2010-08-17 | Kyowa Medex Co., Ltd. | Method for fractional determination of cholesterol in lipoproteins and a reagent therefor |
| JP2000325097A (ja) * | 1999-05-21 | 2000-11-28 | Showa Denko Kk | リポ蛋白質コレステロールの測定方法及び測定試薬 |
| JP2003028881A (ja) * | 2001-07-10 | 2003-01-29 | Orient Cancer Therary:Kk | 難治性自己免疫疾患の測定方法 |
| JP4593026B2 (ja) | 2001-07-18 | 2010-12-08 | 栄研化学株式会社 | SmalldenseLDLの測定方法 |
| JP4476814B2 (ja) | 2002-12-06 | 2010-06-09 | デンカ生研株式会社 | 小粒子低比重リポ蛋白の定量法 |
| JP4606901B2 (ja) | 2005-02-18 | 2011-01-05 | デンカ生研株式会社 | 動脈硬化の診断方法 |
| WO2007001011A1 (ja) | 2005-06-28 | 2007-01-04 | Denka Seiken Co., Ltd. | 食後高脂血症診断のための測定試薬 |
| US8697378B2 (en) | 2005-08-31 | 2014-04-15 | Denka Seiken Co., Ltd. | Method and kit for quantitative determination for small, dense particle low density lipoproteins |
| US20090170139A1 (en) * | 2005-12-09 | 2009-07-02 | Kyowa Medex Co., Ltd. | Method, reagent and kit for measurement of cholesterol in remnant-like particles |
| US8785146B2 (en) * | 2008-04-01 | 2014-07-22 | Beijing Strong Biotechnologies, Inc. | Method for quantitative measurements of HDL-C and LDL-C |
-
2007
- 2007-10-16 EP EP07829906A patent/EP2077333B1/de not_active Not-in-force
- 2007-10-16 JP JP2008540946A patent/JP5111389B2/ja active Active
- 2007-10-16 CN CN2013101864355A patent/CN103305592A/zh active Pending
- 2007-10-16 US US12/377,318 patent/US8163512B2/en active Active
- 2007-10-16 AT AT07829906T patent/ATE498019T1/de not_active IP Right Cessation
- 2007-10-16 DE DE602007012455T patent/DE602007012455D1/de active Active
- 2007-10-16 WO PCT/JP2007/070172 patent/WO2008050636A1/ja not_active Ceased
- 2007-10-16 CN CN2007800334706A patent/CN101512012B/zh active Active
- 2007-10-16 KR KR1020097007184A patent/KR101467926B1/ko not_active Expired - Fee Related
- 2007-10-17 TW TW096138822A patent/TWI421058B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN103305592A (zh) | 2013-09-18 |
| KR20090079887A (ko) | 2009-07-22 |
| TWI421058B (zh) | 2014-01-01 |
| CN101512012B (zh) | 2013-12-04 |
| EP2077333A1 (de) | 2009-07-08 |
| JPWO2008050636A1 (ja) | 2010-02-25 |
| KR101467926B1 (ko) | 2014-12-03 |
| TW200826903A (en) | 2008-07-01 |
| JP5111389B2 (ja) | 2013-01-09 |
| DE602007012455D1 (de) | 2011-03-24 |
| EP2077333A4 (de) | 2009-10-28 |
| US20100041080A1 (en) | 2010-02-18 |
| EP2077333B1 (de) | 2011-02-09 |
| CN101512012A (zh) | 2009-08-19 |
| WO2008050636A1 (fr) | 2008-05-02 |
| US8163512B2 (en) | 2012-04-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |