ATE430199T1 - Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie - Google Patents
Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergieInfo
- Publication number
- ATE430199T1 ATE430199T1 AT99903498T AT99903498T ATE430199T1 AT E430199 T1 ATE430199 T1 AT E430199T1 AT 99903498 T AT99903498 T AT 99903498T AT 99903498 T AT99903498 T AT 99903498T AT E430199 T1 ATE430199 T1 AT E430199T1
- Authority
- AT
- Austria
- Prior art keywords
- ige
- ige binding
- binding
- binding sites
- protein
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 title 1
- 208000026935 allergic disease Diseases 0.000 title 1
- 230000007815 allergy Effects 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 230000004044 response Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 235000017060 Arachis glabrata Nutrition 0.000 abstract 2
- 241001553178 Arachis glabrata Species 0.000 abstract 2
- 235000010777 Arachis hypogaea Nutrition 0.000 abstract 2
- 235000018262 Arachis monticola Nutrition 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 2
- 239000013566 allergen Substances 0.000 abstract 2
- 125000001165 hydrophobic group Chemical group 0.000 abstract 2
- 235000020232 peanut Nutrition 0.000 abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 230000002009 allergenic effect Effects 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 230000000873 masking effect Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7328398P | 1998-01-31 | 1998-01-31 | |
| US7462498P | 1998-02-13 | 1998-02-13 | |
| US7459098P | 1998-02-13 | 1998-02-13 | |
| US7463398P | 1998-02-13 | 1998-02-13 | |
| US14122098A | 1998-08-27 | 1998-08-27 | |
| PCT/US1999/002031 WO1999038978A1 (en) | 1998-01-31 | 1999-01-29 | Methods and reagents for decreasing allergic reactions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE430199T1 true ATE430199T1 (de) | 2009-05-15 |
Family
ID=27535962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99903498T ATE430199T1 (de) | 1998-01-31 | 1999-01-29 | Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7485708B2 (enExample) |
| EP (1) | EP1051494B1 (enExample) |
| JP (1) | JP2002501748A (enExample) |
| AT (1) | ATE430199T1 (enExample) |
| AU (1) | AU743647B2 (enExample) |
| CA (1) | CA2319437C (enExample) |
| DE (1) | DE69940805D1 (enExample) |
| WO (1) | WO1999038978A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE69940805D1 (de) | 1998-01-31 | 2009-06-10 | Sinai School Medicine | Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie |
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| ATE390441T1 (de) * | 1998-10-30 | 2008-04-15 | Novozymes As | Niedrigallergene proteinvarianten |
| US6686164B1 (en) | 1998-10-30 | 2004-02-03 | Novozymes A/S | Low allergenic protein variants |
| US20020009452A1 (en) * | 1999-02-10 | 2002-01-24 | Michael Caplan | Method for altering undesirable immune responses to polypeptides |
| AU3717600A (en) * | 1999-03-02 | 2000-09-21 | Board Of Trustees Of The University Of Arkansas, The | Methods and reagents for decreasing clinical reaction to allergy |
| AU3865400A (en) * | 1999-03-03 | 2000-09-21 | Mount Sinai School Of Medicine Of The City University Of New York, The | Animal model of allergies |
| AU1921601A (en) * | 1999-11-19 | 2001-05-30 | Alabama A & M University | Down-regulation and silencing of allergen genes in transgenic peanut seeds |
| US6943010B1 (en) | 1999-11-19 | 2005-09-13 | Hortense W. Dodo | Down-regulation and silencing of allergen genes in transgenic peanut seeds |
| WO2001040264A2 (en) * | 1999-12-06 | 2001-06-07 | Panacea Pharmaceuticals, Llc. | Peptide antigens |
| CA2394377A1 (en) * | 1999-12-09 | 2001-05-10 | Novozymes A/S | High throughput screening (hts) assays for protein variants with reducedantibody binding capacity |
| WO2001049834A2 (en) | 2000-01-06 | 2001-07-12 | Monsanto Technology Llc | Preparation of deallergenized patatin proteins and patatin permutein proteins |
| GB0006437D0 (en) * | 2000-03-17 | 2000-05-10 | Leuven Res & Dev Vzw | Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens |
| ES2260078T3 (es) * | 2000-04-06 | 2006-11-01 | Seer Pharmaceuticals, Llc. | Sistema de administracion microbiana. |
| AU2001254620A1 (en) * | 2000-04-28 | 2001-11-12 | Novozymes A/S | Lipolytic enzyme variant |
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| AU2005252268B2 (en) * | 2004-06-10 | 2012-06-28 | Aravax Pty Limited | Novel immunointeractive molecules and uses thereof |
| FR2924349B1 (fr) * | 2007-12-03 | 2010-01-01 | Dbv Tech | Methode de desensibilitation aux allergenes |
| EP2243791A1 (en) | 2009-03-03 | 2010-10-27 | PLS-Design GmbH | Cloning and recombinant production of Vespula venom protease and methods of use thereof |
| US9597385B2 (en) | 2012-04-23 | 2017-03-21 | Allertein Therapeutics, Llc | Nanoparticles for treatment of allergy |
| EP2664624A1 (en) | 2012-05-15 | 2013-11-20 | Biomay Ag | Allergen variants |
| DK2914286T3 (da) | 2012-10-30 | 2021-11-08 | Aravax Pty Ltd | Hidtil ukendte immunterapeutiske molekyler og anvendelser deraf |
| EP3760223A1 (en) | 2013-04-03 | 2021-01-06 | N-Fold Llc | Nanoparticle composition for desensitizing a subject to peanut allergens |
| KR20160075532A (ko) | 2013-09-25 | 2016-06-29 | 아라백스 피티와이 엘티디 | 신규한 면역치료제 조성물 및 이의 용도 |
| CN104280555B (zh) * | 2014-10-24 | 2017-09-26 | 江南大学 | 一种快速检测花生过敏原Ara h 2的胶体金试纸条及其制备方法 |
| US9920100B2 (en) | 2015-06-05 | 2018-03-20 | The Chinese University Of Hong Kong | Mimotopes of tropomyosin for use in immunotherapy for shellfish and/or arthropod allergy |
| CN109295250B (zh) * | 2018-10-31 | 2022-03-22 | 四川华汉三创生物科技有限公司 | 一种食源性植物过敏原成分的检测试剂盒和方法 |
| JP7266700B2 (ja) * | 2019-03-13 | 2023-04-28 | プソマーゲン, インコーポレイテッド | アレルギー治療のためのエピトープベースアプローチ及びクローン病のための阻害薬 |
| WO2025212530A1 (en) | 2024-04-01 | 2025-10-09 | N-Fold Llc | Nanoparticle manufacturing |
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| US5891432A (en) * | 1997-07-29 | 1999-04-06 | The Immune Response Corporation | Membrane-bound cytokine compositions comprising GM=CSF and methods of modulating an immune response using same |
| SE9703531D0 (sv) | 1997-09-30 | 1997-09-30 | Rudolf Valenta | Non-anaphlactic forms of allergens and their use |
| US6024961A (en) | 1997-11-14 | 2000-02-15 | Washington University | Recombinant avirulent immunogenic S typhi having rpos positive phenotype |
| JP2002500198A (ja) | 1998-01-09 | 2002-01-08 | サーカシア リミテッド | 脱感作のための方法及び組成物 |
| DE69940805D1 (de) | 1998-01-31 | 2009-06-10 | Sinai School Medicine | Verfahren und reagenzien zur verminderung der klinischen reaktion zur allergie |
| US6248558B1 (en) | 1998-03-31 | 2001-06-19 | Vanderbilt University | Sequence and method for genetic engineering of proteins with cell membrane translocating activity |
| ES2284247T3 (es) | 1998-04-03 | 2007-11-01 | University Of Iowa Research Foundation | Metodos y productos para estimular el sistema inmunitario usando oligonucleotidos y citoquinas inmunoterapeuticos. |
| AU3760100A (en) | 1999-03-16 | 2000-10-04 | Panacea Pharmaceuticals, Llc | Immunostimulatory nucleic acids and antigens |
| AU1921601A (en) | 1999-11-19 | 2001-05-30 | Alabama A & M University | Down-regulation and silencing of allergen genes in transgenic peanut seeds |
| DE60032250T2 (de) * | 2000-12-28 | 2007-03-15 | Biomay Produktions- Und Handels-Aktiengesellschaft | Behandlung von Allergien |
-
1999
- 1999-01-29 DE DE69940805T patent/DE69940805D1/de not_active Expired - Fee Related
- 1999-01-29 WO PCT/US1999/002031 patent/WO1999038978A1/en not_active Ceased
- 1999-01-29 AU AU23505/99A patent/AU743647B2/en not_active Ceased
- 1999-01-29 CA CA002319437A patent/CA2319437C/en not_active Expired - Fee Related
- 1999-01-29 EP EP99903498A patent/EP1051494B1/en not_active Expired - Lifetime
- 1999-01-29 JP JP2000529437A patent/JP2002501748A/ja active Pending
- 1999-01-29 AT AT99903498T patent/ATE430199T1/de not_active IP Right Cessation
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2002
- 2002-08-26 US US10/228,806 patent/US7485708B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2319437C (en) | 2009-06-16 |
| US20030049237A1 (en) | 2003-03-13 |
| JP2002501748A (ja) | 2002-01-22 |
| WO1999038978A1 (en) | 1999-08-05 |
| US7485708B2 (en) | 2009-02-03 |
| CA2319437A1 (en) | 1999-08-05 |
| DE69940805D1 (de) | 2009-06-10 |
| AU743647B2 (en) | 2002-01-31 |
| EP1051494A1 (en) | 2000-11-15 |
| EP1051494B1 (en) | 2009-04-29 |
| AU2350599A (en) | 1999-08-16 |
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