CA2319437C - Methods and reagents for decreasing allergic reactions - Google Patents
Methods and reagents for decreasing allergic reactions Download PDFInfo
- Publication number
- CA2319437C CA2319437C CA002319437A CA2319437A CA2319437C CA 2319437 C CA2319437 C CA 2319437C CA 002319437 A CA002319437 A CA 002319437A CA 2319437 A CA2319437 A CA 2319437A CA 2319437 C CA2319437 C CA 2319437C
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- Prior art keywords
- protein allergen
- ige
- modified
- allergen
- ara
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US60/074,633 | 1998-02-13 | ||
| US14122098A | 1998-08-27 | 1998-08-27 | |
| US09/141,220 | 1998-08-27 | ||
| PCT/US1999/002031 WO1999038978A1 (en) | 1998-01-31 | 1999-01-29 | Methods and reagents for decreasing allergic reactions |
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| AU749749B2 (en) * | 1998-03-16 | 2002-07-04 | Alk-Abello A/S | Mutant recombinant allergens |
| ATE263778T1 (de) * | 1998-10-30 | 2004-04-15 | Novozymes As | Niedrigallergene proteinvarianten |
| US6686164B1 (en) | 1998-10-30 | 2004-02-03 | Novozymes A/S | Low allergenic protein variants |
| US20020009452A1 (en) * | 1999-02-10 | 2002-01-24 | Michael Caplan | Method for altering undesirable immune responses to polypeptides |
| WO2000052154A2 (en) * | 1999-03-02 | 2000-09-08 | The Board Of Trustees Of The University Of Arkansas | Methods and reagents for decreasing clinical reaction to allergy |
| AU3865400A (en) * | 1999-03-03 | 2000-09-21 | Mount Sinai School Of Medicine Of The City University Of New York, The | Animal model of allergies |
| AU1921601A (en) * | 1999-11-19 | 2001-05-30 | Alabama A & M University | Down-regulation and silencing of allergen genes in transgenic peanut seeds |
| US6943010B1 (en) | 1999-11-19 | 2005-09-13 | Hortense W. Dodo | Down-regulation and silencing of allergen genes in transgenic peanut seeds |
| US20020018778A1 (en) * | 1999-12-06 | 2002-02-14 | Caplan Michael J. | Passive desensitization |
| AU779195B2 (en) * | 1999-12-09 | 2005-01-13 | Novozymes A/S | High throughput screening (HTS) assays for protein variants with reduced antibody binding capacity |
| EP1254167A2 (en) * | 2000-01-06 | 2002-11-06 | Monsanto Technology LLC | Preparation of deallergenized patatin proteins and patatin permutein proteins |
| GB0006437D0 (en) | 2000-03-17 | 2000-05-10 | Leuven Res & Dev Vzw | Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens |
| EP1272213B1 (en) * | 2000-04-06 | 2006-03-08 | SEER Pharmaceuticals, LLC. | Microbial delivery system |
| US7226770B2 (en) * | 2000-04-28 | 2007-06-05 | Novozymes A/S | Lipolytic enzyme variant |
| IT1318692B1 (it) * | 2000-09-12 | 2003-08-27 | Consiglio Nazionale Ricerche | Varianti di proteine allergeniche di phleum pratense. |
| US6673580B2 (en) | 2000-10-27 | 2004-01-06 | Genentech, Inc. | Identification and modification of immunodominant epitopes in polypeptides |
| PL214225B1 (pl) * | 2000-11-16 | 2013-07-31 | Alk Abello As | Zrekombinowany alergen, zastosowanie zrekombinowanego alergenu, kompozycja farmaceutyczna, sposób przygotowania kompozycji farmaceutycznej, sposób przygotowania zrekombinowanego alergenu, sekwencja DNA kodujaca zrekombinowany alergen, wektor ekspresyjny, komórka gospodarza oraz sposób produkcji zrekombinowanego zmutowanego alergenu |
| US20030175312A1 (en) * | 2000-11-16 | 2003-09-18 | Alk-Abello A/S | Novel mutant allergens |
| WO2002074250A2 (en) * | 2001-03-16 | 2002-09-26 | Panacea Pharmaceuticals | Methods and reagents for decreasing clinical reaction to allergy |
| US7265208B2 (en) | 2001-05-01 | 2007-09-04 | The Regents Of The University Of California | Fusion molecules and treatment of IgE-mediated allergic diseases |
| ES2244708T3 (es) * | 2002-09-27 | 2005-12-16 | Biomay Produktions- Und Handels- Aktiengesellschaft | Vacunas hipoalergenicas contra la alergia basadas en el alergeno phl p 7 de polen de cola de zorro. |
| AU2005252268B2 (en) * | 2004-06-10 | 2012-06-28 | Aravax Pty Limited | Novel immunointeractive molecules and uses thereof |
| WO2005121166A1 (en) * | 2004-06-10 | 2005-12-22 | Monash University | Novel immunointeractive molecules and uses thereof |
| FR2924349B1 (fr) * | 2007-12-03 | 2010-01-01 | Dbv Tech | Methode de desensibilitation aux allergenes |
| EP2243791A1 (en) | 2009-03-03 | 2010-10-27 | PLS-Design GmbH | Cloning and recombinant production of Vespula venom protease and methods of use thereof |
| WO2013163176A1 (en) | 2012-04-23 | 2013-10-31 | Allertein Therapeutics, Llc | Nanoparticles for treatment of allergy |
| EP2664624A1 (en) | 2012-05-15 | 2013-11-20 | Biomay Ag | Allergen variants |
| NZ707615A (en) | 2012-10-30 | 2019-01-25 | Aravax Pty Ltd | Novel immunotherapeutic molecules and uses thereof |
| CA2907915C (en) | 2013-04-03 | 2023-03-07 | Allertein Therapeutics, Llc | Immunomodulatory nanoparticle compositions comprising a plurality of nanoparticles comprising biodegradable or biocompatible polymers and hydrophilic and hydrophobic cellular components |
| WO2015042664A1 (en) | 2013-09-25 | 2015-04-02 | Monash University | Novel immunotherapeutic composition and uses thereof |
| CN104280555B (zh) * | 2014-10-24 | 2017-09-26 | 江南大学 | 一种快速检测花生过敏原Ara h 2的胶体金试纸条及其制备方法 |
| US9920100B2 (en) | 2015-06-05 | 2018-03-20 | The Chinese University Of Hong Kong | Mimotopes of tropomyosin for use in immunotherapy for shellfish and/or arthropod allergy |
| CN109295250B (zh) * | 2018-10-31 | 2022-03-22 | 四川华汉三创生物科技有限公司 | 一种食源性植物过敏原成分的检测试剂盒和方法 |
| CN113631231A (zh) * | 2019-03-13 | 2021-11-09 | 普梭梅根公司 | 用于过敏治疗的基于表位的方法和克罗恩病的抑制剂 |
| US20240390485A1 (en) * | 2021-08-03 | 2024-11-28 | Ukko Inc. | Hypoallergenic peanut allergens, production and use thereof |
| WO2025212530A1 (en) | 2024-04-01 | 2025-10-09 | N-Fold Llc | Nanoparticle manufacturing |
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1999
- 1999-01-29 CA CA002319437A patent/CA2319437C/en not_active Expired - Fee Related
- 1999-01-29 EP EP99903498A patent/EP1051494B1/en not_active Expired - Lifetime
- 1999-01-29 DE DE69940805T patent/DE69940805D1/de not_active Expired - Fee Related
- 1999-01-29 JP JP2000529437A patent/JP2002501748A/ja active Pending
- 1999-01-29 AU AU23505/99A patent/AU743647B2/en not_active Ceased
- 1999-01-29 AT AT99903498T patent/ATE430199T1/de not_active IP Right Cessation
- 1999-01-29 WO PCT/US1999/002031 patent/WO1999038978A1/en not_active Ceased
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2002
- 2002-08-26 US US10/228,806 patent/US7485708B2/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| US20030049237A1 (en) | 2003-03-13 |
| ATE430199T1 (de) | 2009-05-15 |
| AU743647B2 (en) | 2002-01-31 |
| EP1051494B1 (en) | 2009-04-29 |
| US7485708B2 (en) | 2009-02-03 |
| WO1999038978A1 (en) | 1999-08-05 |
| EP1051494A1 (en) | 2000-11-15 |
| AU2350599A (en) | 1999-08-16 |
| JP2002501748A (ja) | 2002-01-22 |
| CA2319437A1 (en) | 1999-08-05 |
| DE69940805D1 (de) | 2009-06-10 |
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