ATE389178T1 - Polymeraffinitätsmatrix, verfahren zu ihrer herstellung und verwendung - Google Patents

Polymeraffinitätsmatrix, verfahren zu ihrer herstellung und verwendung

Info

Publication number
ATE389178T1
ATE389178T1 AT03738845T AT03738845T ATE389178T1 AT E389178 T1 ATE389178 T1 AT E389178T1 AT 03738845 T AT03738845 T AT 03738845T AT 03738845 T AT03738845 T AT 03738845T AT E389178 T1 ATE389178 T1 AT E389178T1
Authority
AT
Austria
Prior art keywords
fluid
matrix
production
affinity matrix
polymer affinity
Prior art date
Application number
AT03738845T
Other languages
English (en)
Inventor
Wolfgang Rapp
Reinhold Deppisch
Hermann Goehl
Bernd Wittner
Werner Beck
Original Assignee
Gambro Lundia Ab
Wolfgang Rapp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Lundia Ab, Wolfgang Rapp filed Critical Gambro Lundia Ab
Application granted granted Critical
Publication of ATE389178T1 publication Critical patent/ATE389178T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • External Artificial Organs (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
AT03738845T 2002-07-08 2003-07-04 Polymeraffinitätsmatrix, verfahren zu ihrer herstellung und verwendung ATE389178T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0202114A SE526038C2 (sv) 2002-07-08 2002-07-08 Polymeraffinitetsmatris, förfarande för framställning därav och anvädning därav

Publications (1)

Publication Number Publication Date
ATE389178T1 true ATE389178T1 (de) 2008-03-15

Family

ID=20288453

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03738845T ATE389178T1 (de) 2002-07-08 2003-07-04 Polymeraffinitätsmatrix, verfahren zu ihrer herstellung und verwendung

Country Status (11)

Country Link
US (2) US20060134595A1 (de)
EP (1) EP1519721B1 (de)
JP (1) JP2006505385A (de)
KR (1) KR101036995B1 (de)
CN (1) CN1665494A (de)
AT (1) ATE389178T1 (de)
AU (1) AU2003245217A1 (de)
DE (1) DE60319702T2 (de)
ES (1) ES2304518T3 (de)
SE (1) SE526038C2 (de)
WO (1) WO2004004707A1 (de)

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CN102621296A (zh) * 2012-01-06 2012-08-01 天津医科大学 一种带有间隔臂的羧化聚苯乙烯微球上偶联蛋白质的方法
JP6231263B2 (ja) * 2012-07-17 2017-11-15 株式会社島津製作所 アフィニティ支持体及びそれを用いた物質の捕捉方法
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CN104045824B (zh) * 2014-07-03 2015-08-26 湖南尔康制药股份有限公司 一种固相负载法合成聚乙二醇-12-羟基硬脂酸酯的方法
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CN104959120B (zh) * 2015-06-19 2017-05-10 佛山市博新生物科技有限公司 一种用于血液灌流的炎性因子吸附剂及制备方法
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EP3506999A1 (de) * 2016-09-05 2019-07-10 Drei Lilien PVG GmbH & Co. KG Offenporige membran mit innerem raumdurchspannendem polymerem strukturnetzwerk zur elektrophoretischen stoffselektiven separation sowie verfahren zu deren herstellung und anwendung
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CN107764803B (zh) * 2017-09-21 2021-04-13 中山大学 一种运用电化学发光成像识别技术的生物标志物检测方法
CN107475454B (zh) * 2017-09-21 2020-05-26 中山大学 基于电化学发光放大原理的寨卡病毒核酸检测方法
CN107488723B (zh) * 2017-09-21 2020-11-27 中山大学 基于电化学发光级联放大原理的端粒酶活性检测方法
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Also Published As

Publication number Publication date
AU2003245217A1 (en) 2004-01-23
WO2004004707A1 (en) 2004-01-15
CN1665494A (zh) 2005-09-07
US20090047654A1 (en) 2009-02-19
SE0202114D0 (sv) 2002-07-08
EP1519721A1 (de) 2005-04-06
KR101036995B1 (ko) 2011-05-25
JP2006505385A (ja) 2006-02-16
US20060134595A1 (en) 2006-06-22
ES2304518T3 (es) 2008-10-16
KR20050025322A (ko) 2005-03-14
DE60319702D1 (de) 2008-04-24
SE0202114L (sv) 2004-01-09
SE526038C2 (sv) 2005-06-21
DE60319702T2 (de) 2009-03-12
EP1519721B1 (de) 2008-03-12

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