ATE377600T1 - Imidazopyrazine als cdk-inhibitoren - Google Patents

Imidazopyrazine als cdk-inhibitoren

Info

Publication number
ATE377600T1
ATE377600T1 AT03754658T AT03754658T ATE377600T1 AT E377600 T1 ATE377600 T1 AT E377600T1 AT 03754658 T AT03754658 T AT 03754658T AT 03754658 T AT03754658 T AT 03754658T AT E377600 T1 ATE377600 T1 AT E377600T1
Authority
AT
Austria
Prior art keywords
imidazopyrazine
cdk inhibitors
cdk
inhibitors
Prior art date
Application number
AT03754658T
Other languages
German (de)
English (en)
Inventor
Kamil Paruch
Timothy Guzi
Michael Dwyer
Ronald Doll
Viyyoor Girijavallabhan
Alan Mallams
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE377600T1 publication Critical patent/ATE377600T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03754658T 2002-09-23 2003-09-19 Imidazopyrazine als cdk-inhibitoren ATE377600T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41299702P 2002-09-23 2002-09-23

Publications (1)

Publication Number Publication Date
ATE377600T1 true ATE377600T1 (de) 2007-11-15

Family

ID=32030951

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03754658T ATE377600T1 (de) 2002-09-23 2003-09-19 Imidazopyrazine als cdk-inhibitoren

Country Status (18)

Country Link
US (2) US6919341B2 (cg-RX-API-DMAC10.html)
EP (1) EP1543008B1 (cg-RX-API-DMAC10.html)
JP (1) JP4799864B2 (cg-RX-API-DMAC10.html)
KR (1) KR20050057520A (cg-RX-API-DMAC10.html)
CN (1) CN1694886A (cg-RX-API-DMAC10.html)
AR (1) AR041347A1 (cg-RX-API-DMAC10.html)
AT (1) ATE377600T1 (cg-RX-API-DMAC10.html)
AU (1) AU2003272476B2 (cg-RX-API-DMAC10.html)
CA (1) CA2499756C (cg-RX-API-DMAC10.html)
DE (1) DE60317353T2 (cg-RX-API-DMAC10.html)
ES (1) ES2293015T3 (cg-RX-API-DMAC10.html)
MX (1) MXPA05003120A (cg-RX-API-DMAC10.html)
MY (1) MY134589A (cg-RX-API-DMAC10.html)
NZ (2) NZ538685A (cg-RX-API-DMAC10.html)
PE (1) PE20050081A1 (cg-RX-API-DMAC10.html)
TW (1) TW200413378A (cg-RX-API-DMAC10.html)
WO (1) WO2004026877A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA200502375B (cg-RX-API-DMAC10.html)

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BR0309398A (pt) 2002-04-19 2005-02-01 Cellular Genomics Inc Composto ou um seu sal, hidrato, solvato, forma cristalina, diastereÈmero, prodroga farmaceuticamente aceitável, ou misturas deles, composição farmacêutica, e, métodos para tratar uma condição envolvida com a cinase em um mamìfero, para tratar câncer, e para identificar uma cinase
KR20060010709A (ko) * 2002-09-23 2006-02-02 쉐링 코포레이션 사이클린 의존성 키나제 억제제로서의 신규한 이미다조피라진
JP4799864B2 (ja) * 2002-09-23 2011-10-26 シェーリング コーポレイション サイクリン依存性キナーゼインヒビターとしてのイミダゾピラジン

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AU2003272476A1 (en) 2004-04-08
HK1072056A1 (en) 2005-08-12
KR20050057520A (ko) 2005-06-16
AU2003272476B2 (en) 2007-07-05
ZA200502375B (en) 2005-09-27
US7432265B2 (en) 2008-10-07
EP1543008A1 (en) 2005-06-22
DE60317353D1 (de) 2007-12-20
CA2499756A1 (en) 2004-04-01
JP2006507253A (ja) 2006-03-02
NZ538685A (en) 2008-02-29
DE60317353T2 (de) 2008-08-28
EP1543008B1 (en) 2007-11-07
CN1694886A (zh) 2005-11-09
US20050130980A1 (en) 2005-06-16
CA2499756C (en) 2011-07-12
TW200413378A (en) 2004-08-01
US20040063715A1 (en) 2004-04-01
JP4799864B2 (ja) 2011-10-26
MY134589A (en) 2007-12-31
AR041347A1 (es) 2005-05-11
ES2293015T3 (es) 2008-03-16
WO2004026877A1 (en) 2004-04-01
US6919341B2 (en) 2005-07-19
PE20050081A1 (es) 2005-03-01
NZ563374A (en) 2009-06-26
MXPA05003120A (es) 2005-06-22

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