ATE362479T1 - 14 bis 15 gliedrige makrolide mit antibakterieller aktivität - Google Patents

14 bis 15 gliedrige makrolide mit antibakterieller aktivität

Info

Publication number
ATE362479T1
ATE362479T1 AT02779670T AT02779670T ATE362479T1 AT E362479 T1 ATE362479 T1 AT E362479T1 AT 02779670 T AT02779670 T AT 02779670T AT 02779670 T AT02779670 T AT 02779670T AT E362479 T1 ATE362479 T1 AT E362479T1
Authority
AT
Austria
Prior art keywords
macrolids
antibacterial activity
antibacterial
activity
element macrolids
Prior art date
Application number
AT02779670T
Other languages
German (de)
English (en)
Inventor
Sulejman Alihodzic
Daniele Andreotti
Andrea Berdik
Ilaria Bientinesi
Stefano Biondi
Manuela Ciraco
Federica Damiani
Marko Djerek
Miljenko Dumic
Vesna Erakovic
Antun Hutinec
Gorjana Lazarevski
Sergio Lociuro
Natasa Marsic
Zorica Marusic-Istuk
Stjepan Mutak
Alfredo Paio
Drazen Pavlovic
Anna Quaglia
Vlado Stimac
Jessica Tibasco
Wolfgang Schoenfeld
Original Assignee
Glaxo Group Ltd
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Glaxosmithkline Zagreb filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE362479T1 publication Critical patent/ATE362479T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
AT02779670T 2001-11-14 2002-11-13 14 bis 15 gliedrige makrolide mit antibakterieller aktivität ATE362479T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0127349.9A GB0127349D0 (en) 2001-11-14 2001-11-14 Macrolides

Publications (1)

Publication Number Publication Date
ATE362479T1 true ATE362479T1 (de) 2007-06-15

Family

ID=9925777

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02779670T ATE362479T1 (de) 2001-11-14 2002-11-13 14 bis 15 gliedrige makrolide mit antibakterieller aktivität

Country Status (20)

Country Link
US (1) US7202221B2 (https=)
EP (1) EP1453846B1 (https=)
JP (1) JP2005515978A (https=)
CN (1) CN1307194C (https=)
AR (1) AR037371A1 (https=)
AT (1) ATE362479T1 (https=)
BR (1) BR0214132A (https=)
CA (1) CA2466975A1 (https=)
DE (1) DE60220180T2 (https=)
EA (1) EA007433B1 (https=)
ES (1) ES2287332T3 (https=)
GB (1) GB0127349D0 (https=)
HR (1) HRP20040433A2 (https=)
HU (1) HUP0402225A3 (https=)
IL (1) IL161710A0 (https=)
PL (1) PL371472A1 (https=)
RS (1) RS41904A (https=)
UA (1) UA77210C2 (https=)
WO (1) WO2003042228A1 (https=)
ZA (1) ZA200403684B (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995143B2 (en) * 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US7022679B2 (en) 2002-05-13 2006-04-04 Enanta Pharmaceuticals, Inc. Processes for the preparation of 6-11 bicyclic erythromycin derivatives
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
US7910558B2 (en) 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7135573B2 (en) 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
NZ536061A (en) * 2002-05-14 2008-09-26 Univ California Substituted quinolone carboxylic acids, their derivatives, site of action, and uses thereof
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
SI1628989T1 (sl) * 2003-05-13 2007-06-30 Glaxo Group Ltd Nove cikliäśne spojine s 14 in 15 obroäśnimi äśleni
GB0310986D0 (en) 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310980D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
WO2005070113A2 (en) 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
JP5383037B2 (ja) 2004-02-27 2014-01-08 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 大環状化合物およびそれらを製造し使用する方法
BRPI0510328A (pt) * 2004-05-06 2007-10-23 Glaxosmithkline Zagreb macrolìdeos ligados a éster úteis para o tratamento de infecções microbianas
WO2005108413A1 (en) * 2004-05-06 2005-11-17 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O Carbamate linked macrolides useful for the treatment of microbial infections
WO2006047167A2 (en) * 2004-10-21 2006-05-04 Janssen Pharmaceutica, N.V. 9 alkyl and 9 alkylidenyl 6-0 alkyl-11, 12 carbamate ketolide antimicrobials
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424951D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424959D0 (en) 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
DK2049556T3 (da) * 2006-08-09 2013-08-12 Basilea Pharmaceutica Ag Nye makrolider anvendelige mod inflammatoriske og allergiske sygdomme
WO2008023248A2 (en) 2006-08-24 2008-02-28 Wockhardt Research Centre Novel macrolides and ketolides having antimicrobial activity
WO2009106419A1 (en) 2008-02-08 2009-09-03 Basilea Pharmaceutica Ag New macrolides and their use
BRPI1011959A2 (pt) 2009-05-27 2016-04-26 Wockhardt Research Center compostos de cetolídeo tendo atividade antimicrobiana.
WO2012076989A1 (en) 2010-12-09 2012-06-14 Wockhardt Limited Ketolide compounds
KR20140004187A (ko) * 2011-01-31 2014-01-10 메이지 세이카 파루마 가부시키가이샤 신규 마크로라이드 유도체
KR101567658B1 (ko) 2011-03-01 2015-11-09 욱크하르트 리미티드 케톨리드 중간체의 제조 방법
CN119060110A (zh) * 2023-05-30 2024-12-03 北京理工大学 一种红霉素衍生物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126344A2 (en) 1983-05-20 1984-11-28 Abbott Laboratories Tripeptide esters of therapeutic agents
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
WO1990011288A1 (en) 1989-03-28 1990-10-04 Abbott Laboratories Erythromycin derivatives
CA2064634C (en) 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
EP1007530B1 (en) 1996-05-07 2005-11-16 Abbott Laboratories 6-o-substituted erythromycin compounds and method for making same
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
US6262030B1 (en) * 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
EA200100983A1 (ru) 1999-05-24 2002-10-31 Пфайзер Продактс Инк. Производные 13-метилэритромицина
PT1206476E (pt) 1999-08-24 2006-05-31 Abbott Lab 9a-azalidos com actividade antibacteriana
US6946446B2 (en) * 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
ES2254389T3 (es) 2000-02-24 2006-06-16 Abbott Laboratories Agentes anti-infecciosos utiles contra cepas bacterianas resistntes a multiples farmacos.
JP2002173498A (ja) 2000-09-27 2002-06-21 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides

Also Published As

Publication number Publication date
EA007433B1 (ru) 2006-10-27
ZA200403684B (en) 2005-09-13
GB0127349D0 (en) 2002-01-02
EP1453846B1 (en) 2007-05-16
DE60220180T2 (de) 2008-01-17
JP2005515978A (ja) 2005-06-02
DE60220180D1 (de) 2007-06-28
AR037371A1 (es) 2004-11-03
PL371472A1 (en) 2005-06-13
CA2466975A1 (en) 2003-05-22
EA200400536A1 (ru) 2004-12-30
BR0214132A (pt) 2004-09-14
CN1307194C (zh) 2007-03-28
CN1612888A (zh) 2005-05-04
IL161710A0 (en) 2004-09-27
EP1453846A1 (en) 2004-09-08
RS41904A (sr) 2006-10-27
US20050080025A1 (en) 2005-04-14
US7202221B2 (en) 2007-04-10
UA77210C2 (en) 2006-11-15
HUP0402225A2 (hu) 2005-02-28
HUP0402225A3 (en) 2006-01-30
ES2287332T3 (es) 2007-12-16
WO2003042228A1 (en) 2003-05-22
HRP20040433A2 (en) 2005-04-30

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties