ATE264843T1 - Antibakterielle mutiline - Google Patents

Antibakterielle mutiline

Info

Publication number
ATE264843T1
ATE264843T1 AT01972046T AT01972046T ATE264843T1 AT E264843 T1 ATE264843 T1 AT E264843T1 AT 01972046 T AT01972046 T AT 01972046T AT 01972046 T AT01972046 T AT 01972046T AT E264843 T1 ATE264843 T1 AT E264843T1
Authority
AT
Austria
Prior art keywords
mutiline
antibacterial
antibacterial mutiline
Prior art date
Application number
AT01972046T
Other languages
English (en)
Inventor
Gerd Ascher
Heinz Berner
Johannes Hildebrandt
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0022439A external-priority patent/GB0022439D0/en
Priority claimed from GB0022440A external-priority patent/GB0022440D0/en
Priority claimed from GB0024674A external-priority patent/GB0024674D0/en
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Application granted granted Critical
Publication of ATE264843T1 publication Critical patent/ATE264843T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT01972046T 2000-09-13 2001-09-11 Antibakterielle mutiline ATE264843T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0022439A GB0022439D0 (en) 2000-09-13 2000-09-13 Organic compounds
GB0022440A GB0022440D0 (en) 2000-09-13 2000-09-13 Organic Compounds
GB0024674A GB0024674D0 (en) 2000-10-09 2000-10-09 Organic compounds
PCT/EP2001/010502 WO2002022580A1 (en) 2000-09-13 2001-09-11 Antibacterials mutilins

Publications (1)

Publication Number Publication Date
ATE264843T1 true ATE264843T1 (de) 2004-05-15

Family

ID=27255885

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01972046T ATE264843T1 (de) 2000-09-13 2001-09-11 Antibakterielle mutiline

Country Status (17)

Country Link
US (3) US7169804B2 (de)
EP (1) EP1320525B1 (de)
JP (1) JP5134181B2 (de)
CN (1) CN1288134C (de)
AR (1) AR030651A1 (de)
AT (1) ATE264843T1 (de)
AU (1) AU2001291854A1 (de)
BR (1) BRPI0113837B8 (de)
CA (1) CA2418538C (de)
DE (1) DE60102936T2 (de)
ES (1) ES2220809T3 (de)
HK (1) HK1079506A1 (de)
MY (1) MY133930A (de)
PE (1) PE20020676A1 (de)
PT (1) PT1320525E (de)
TW (1) TWI306852B (de)
WO (1) WO2002022580A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9918037D0 (en) * 1999-07-30 1999-09-29 Biochemie Gmbh Organic compounds
GB0207495D0 (en) 2002-03-28 2002-05-08 Biochemie Gmbh Organic compounds
GB0209262D0 (en) * 2002-04-23 2002-06-05 Biochemie Gmbh Organic compounds
EP1534678B1 (de) * 2002-07-24 2007-10-31 Nabriva Therapeutics Forschungs GmbH Pleuromutilinderivate als antimikrobielle mittel
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
US7544963B2 (en) * 2005-04-29 2009-06-09 Cree, Inc. Binary group III-nitride based high electron mobility transistors
GB0513058D0 (en) * 2005-06-27 2005-08-03 Sandoz Ag Organic compounds
WO2007037518A1 (ja) * 2005-09-29 2007-04-05 Dainippon Sumitomo Pharma Co., Ltd. ムチリン誘導体及びそれを含有する医薬組成物
EP1808431A1 (de) * 2006-01-16 2007-07-18 Nabriva Therapeutics Forschungs GmbH Mutilin Derivate und ihre Verwendung als Arzneimittel
CA2654450A1 (en) * 2006-06-05 2007-12-13 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted erythromycin analogs
EP1908750A1 (de) * 2006-10-05 2008-04-09 Nabriva Therapeutics Forschungs GmbH Verfahren zur Herstellung von Pleuromutilinen
WO2008143343A1 (ja) 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
US20100184987A1 (en) * 2008-11-13 2010-07-22 Teva Pharmaceutical Industries Ltd. Preparation of Retapamulin via its Pleuromutilin-thiol precursor
CN103709115A (zh) * 2012-10-09 2014-04-09 山东亨利医药科技有限责任公司 截短侧耳素类抗生素衍生物
TWI762573B (zh) 2017-02-10 2022-05-01 奧地利商納畢瓦治療有限責任公司 截短側耳素之純化

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789629A (fr) * 1971-10-05 1973-04-03 Sandoz Sa Nouveaux derives de la pleuromutiline, leur preparation et leurapplication en therapeutique
DE2811314A1 (de) * 1978-03-16 1979-09-27 Sandoz Ag Kokzidiostatisches kombinationspraeparat
DE2966635D1 (en) 1979-01-12 1984-03-08 Sandoz Ag New pleuromutilin derivatives, their production and pharmaceutical compositions containing them
ZA80175B (en) * 1979-01-12 1981-08-26 Sandoz Ltd New pleuromutilin derivatives, their production and use
EP0153277B1 (de) * 1984-02-17 1987-08-26 Sandoz Ag Neue Pleuromutilinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung
JP3054875B2 (ja) * 1995-02-13 2000-06-19 株式会社小松製作所 プラズマトーチ
IL124912A0 (en) * 1996-01-03 1999-01-26 Smithkline Beecham Plc Carbamoyloxy derivatives of mutiline and their use as antibacterials
UY25225A1 (es) 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
WO2000027790A1 (en) 1998-11-11 2000-05-18 Smithkline Beecham P.L.C. Mutilin compounds
AU3036200A (en) 1998-12-18 2000-07-12 Smithkline Beecham Plc Mutilin 14-ester derivatives having antibacterial activity
GB9918037D0 (en) * 1999-07-30 1999-09-29 Biochemie Gmbh Organic compounds
GB0207495D0 (en) * 2002-03-28 2002-05-08 Biochemie Gmbh Organic compounds
EP1534678B1 (de) * 2002-07-24 2007-10-31 Nabriva Therapeutics Forschungs GmbH Pleuromutilinderivate als antimikrobielle mittel

Also Published As

Publication number Publication date
WO2002022580A1 (en) 2002-03-21
CN1288134C (zh) 2006-12-06
TWI306852B (en) 2009-03-01
PE20020676A1 (es) 2002-08-27
MY133930A (en) 2007-11-30
EP1320525A1 (de) 2003-06-25
HK1079506A1 (en) 2006-04-07
EP1320525B1 (de) 2004-04-21
ES2220809T3 (es) 2004-12-16
CN1633415A (zh) 2005-06-29
US20070135483A1 (en) 2007-06-14
US7169804B2 (en) 2007-01-30
US20040102482A1 (en) 2004-05-27
US7569587B2 (en) 2009-08-04
CA2418538A1 (en) 2002-03-21
BR0113837A (pt) 2003-06-03
JP5134181B2 (ja) 2013-01-30
BRPI0113837B8 (pt) 2021-05-25
AR030651A1 (es) 2003-08-27
JP2004509107A (ja) 2004-03-25
BRPI0113837B1 (pt) 2019-01-29
PT1320525E (pt) 2004-09-30
DE60102936D1 (de) 2004-05-27
CA2418538C (en) 2009-12-22
AU2001291854A1 (en) 2002-03-26
US20090209584A1 (en) 2009-08-20
DE60102936T2 (de) 2005-03-24

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Legal Events

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EEIH Change in the person of patent owner
EEFA Change of the company name