ATE362479T1 - 14 bis 15 gliedrige makrolide mit antibakterieller aktivität - Google Patents

14 bis 15 gliedrige makrolide mit antibakterieller aktivität

Info

Publication number
ATE362479T1
ATE362479T1 AT02779670T AT02779670T ATE362479T1 AT E362479 T1 ATE362479 T1 AT E362479T1 AT 02779670 T AT02779670 T AT 02779670T AT 02779670 T AT02779670 T AT 02779670T AT E362479 T1 ATE362479 T1 AT E362479T1
Authority
AT
Austria
Prior art keywords
macrolids
antibacterial activity
antibacterial
activity
element macrolids
Prior art date
Application number
AT02779670T
Other languages
German (de)
English (en)
Inventor
Sulejman Alihodzic
Daniele Andreotti
Andrea Berdik
Ilaria Bientinesi
Stefano Biondi
Manuela Ciraco
Federica Damiani
Marko Djerek
Miljenko Dumic
Vesna Erakovic
Antun Hutinec
Gorjana Lazarevski
Sergio Lociuro
Natasa Marsic
Zorica Marusic-Istuk
Stjepan Mutak
Alfredo Paio
Drazen Pavlovic
Anna Quaglia
Vlado Stimac
Jessica Tibasco
Wolfgang Schoenfeld
Original Assignee
Glaxo Group Ltd
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Glaxosmithkline Zagreb filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE362479T1 publication Critical patent/ATE362479T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
AT02779670T 2001-11-14 2002-11-13 14 bis 15 gliedrige makrolide mit antibakterieller aktivität ATE362479T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0127349.9A GB0127349D0 (en) 2001-11-14 2001-11-14 Macrolides

Publications (1)

Publication Number Publication Date
ATE362479T1 true ATE362479T1 (de) 2007-06-15

Family

ID=9925777

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02779670T ATE362479T1 (de) 2001-11-14 2002-11-13 14 bis 15 gliedrige makrolide mit antibakterieller aktivität

Country Status (20)

Country Link
US (1) US7202221B2 (cg-RX-API-DMAC7.html)
EP (1) EP1453846B1 (cg-RX-API-DMAC7.html)
JP (1) JP2005515978A (cg-RX-API-DMAC7.html)
CN (1) CN1307194C (cg-RX-API-DMAC7.html)
AR (1) AR037371A1 (cg-RX-API-DMAC7.html)
AT (1) ATE362479T1 (cg-RX-API-DMAC7.html)
BR (1) BR0214132A (cg-RX-API-DMAC7.html)
CA (1) CA2466975A1 (cg-RX-API-DMAC7.html)
DE (1) DE60220180T2 (cg-RX-API-DMAC7.html)
EA (1) EA007433B1 (cg-RX-API-DMAC7.html)
ES (1) ES2287332T3 (cg-RX-API-DMAC7.html)
GB (1) GB0127349D0 (cg-RX-API-DMAC7.html)
HR (1) HRP20040433A2 (cg-RX-API-DMAC7.html)
HU (1) HUP0402225A3 (cg-RX-API-DMAC7.html)
IL (1) IL161710A0 (cg-RX-API-DMAC7.html)
PL (1) PL371472A1 (cg-RX-API-DMAC7.html)
RS (1) RS41904A (cg-RX-API-DMAC7.html)
UA (1) UA77210C2 (cg-RX-API-DMAC7.html)
WO (1) WO2003042228A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200403684B (cg-RX-API-DMAC7.html)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6995143B2 (en) * 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US7135573B2 (en) 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US7910558B2 (en) 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7022679B2 (en) 2002-05-13 2006-04-04 Enanta Pharmaceuticals, Inc. Processes for the preparation of 6-11 bicyclic erythromycin derivatives
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
KR20040107525A (ko) * 2002-05-14 2004-12-20 더 리전트 오브 더 유니버시티 오브 캘리포니아 치환된 퀴놀론 카르복실산, 이들의 유도체, 그의 작용부위 및 용도
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
GB0225384D0 (en) 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
ATE348837T1 (de) * 2003-05-13 2007-01-15 Glaxo Group Ltd Neue 14- und 15-gliedrige ringverbindungen
GB0310980D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310986D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
WO2005030227A1 (en) 2003-09-23 2005-04-07 Enanta Pharmaceuticals, Inc. 9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
WO2005070113A2 (en) 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
US8202843B2 (en) 2004-02-27 2012-06-19 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
EP1756134A1 (en) * 2004-05-06 2007-02-28 GlaxoSmithKline istrazivacki centar Zagreb d.o.o. Carbamate linked macrolides useful for the treatment of microbial infections
JP2007536371A (ja) * 2004-05-06 2007-12-13 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 微生物感染症の治療に有用なエステル結合マクロライド
WO2006047167A2 (en) * 2004-10-21 2006-05-04 Janssen Pharmaceutica, N.V. 9 alkyl and 9 alkylidenyl 6-0 alkyl-11, 12 carbamate ketolide antimicrobials
GB0424959D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424951D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424958D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
GB0424961D0 (en) * 2004-11-11 2004-12-15 Glaxo Group Ltd Novel compounds
WO2008017696A1 (en) * 2006-08-09 2008-02-14 Basilea Pharmaceutica Ag New macrolides useful against inflammatory and allergic disseases
CN101541331A (zh) 2006-08-24 2009-09-23 沃克哈特研究中心 具有抗微生物活性的新颖大环内酯和酮内酯
KR101617897B1 (ko) 2008-02-08 2016-05-03 바실리어 파마슈티카 아게 신규 마크로라이드 및 그의 용도
EP2435460B1 (en) 2009-05-27 2015-01-07 Wockhardt Limited Ketolide compounds having antimicrobial activity
CN103384676B (zh) 2010-12-09 2016-02-03 沃克哈特有限公司 酮内酯化合物
CA2826174A1 (en) * 2011-01-31 2012-08-09 Meiji Seika Pharma Co., Ltd. Novel macrolide derivative
CN103619849B (zh) 2011-03-01 2016-05-25 沃克哈特有限公司 酮内酯中间体的制备方法
CN119060110A (zh) * 2023-05-30 2024-12-03 北京理工大学 一种红霉素衍生物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0126344A2 (en) 1983-05-20 1984-11-28 Abbott Laboratories Tripeptide esters of therapeutic agents
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
AU623764B2 (en) * 1989-03-28 1992-05-21 Abbott Laboratories Erythromycin derivatives
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
BR9708929A (pt) 1996-05-07 1999-08-03 Abbott Lab Composto composição farmacêutica e processos para controlar uma infecção bacteriana em um mamífero e para preparar compostos de macrólidos
EP0895999A1 (en) * 1997-08-06 1999-02-10 Pfizer Products Inc. C-4" substituted macrolide antibiotics
US6262030B1 (en) * 1998-11-03 2001-07-17 Pfizer Inc. Erythromycin derivatives
EP1180110A1 (en) 1999-05-24 2002-02-20 Pfizer Products Inc. 13-methyl-erythromycin derivatives
WO2001014397A1 (en) 1999-08-24 2001-03-01 Abbott Laboratories 9a-azalides with antibacterial activity
US6946446B2 (en) * 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
WO2001063539A2 (en) 2000-02-24 2001-08-30 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
JP2002173498A (ja) 2000-09-27 2002-06-21 Hokuriku Seiyaku Co Ltd エリスロマイシン誘導体
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides

Also Published As

Publication number Publication date
IL161710A0 (en) 2004-09-27
UA77210C2 (en) 2006-11-15
RS41904A (sr) 2006-10-27
GB0127349D0 (en) 2002-01-02
CA2466975A1 (en) 2003-05-22
AR037371A1 (es) 2004-11-03
ZA200403684B (en) 2005-09-13
ES2287332T3 (es) 2007-12-16
EP1453846A1 (en) 2004-09-08
DE60220180D1 (de) 2007-06-28
HUP0402225A3 (en) 2006-01-30
HUP0402225A2 (hu) 2005-02-28
EA007433B1 (ru) 2006-10-27
EA200400536A1 (ru) 2004-12-30
JP2005515978A (ja) 2005-06-02
CN1612888A (zh) 2005-05-04
CN1307194C (zh) 2007-03-28
PL371472A1 (en) 2005-06-13
HRP20040433A2 (en) 2005-04-30
DE60220180T2 (de) 2008-01-17
BR0214132A (pt) 2004-09-14
US7202221B2 (en) 2007-04-10
US20050080025A1 (en) 2005-04-14
EP1453846B1 (en) 2007-05-16
WO2003042228A1 (en) 2003-05-22

Similar Documents

Publication Publication Date Title
ATE362479T1 (de) 14 bis 15 gliedrige makrolide mit antibakterieller aktivität
DE60209785D1 (de) Gipszusammensetzung mit verbesserter deformationsstabilität
DK1440077T3 (da) Syntetiske heparinpentasaccharider
DE60214410D1 (de) Multirotationscodierer
DE60113450D1 (de) Antimikrobielle chinolone
DE60209302D1 (de) Elektronisch leitfähige Polythiophenteilchen enthaltende Zusammensetzung
NO20035216D0 (no) Reiseverdiindeks
DE60040557D1 (de) Elektrolumineszierendes element
BR0208971B1 (pt) produto absorvente com ajuste melhorado.
BR0208970B1 (pt) produto absorvente com ajuste melhorado.
BR0208969B1 (pt) produto absorvente com ajuste melhorado.
DE60238111D1 (de) Viszeralfettmesser mit tonometer
DE60101126D1 (de) Tintenstrahlaufzeichnungselement
ATE264843T1 (de) Antibakterielle mutiline
FI20011518A0 (fi) Liikeanalysaattori
ATE387204T1 (de) Zusammensetzung mit induzierendem kathartischen effekt
DE60009219D1 (de) Linearer Reissverschluss
DE50110880D1 (de) Gleitelementvorrichtung
DE60102606D1 (de) Tintenstrahlaufzeichnungselement
DE60143148D1 (de) En mit honigwaben
DE60135877D1 (de) Antibakterielle zusammensetzung
ATE315042T1 (de) 9a-azalide mit antibakterieller wirkung
DE60104016D1 (de) Pestizide zusammensetzung
DE50207947D1 (de) Linearwälzlagerelement
DE60124516D1 (de) Kombination des lezithins mit ascorbinsäure

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties