ATE346644T1 - Vorrichtung zur transdermalen verabreichung von einer substanz - Google Patents

Vorrichtung zur transdermalen verabreichung von einer substanz

Info

Publication number
ATE346644T1
ATE346644T1 AT00116947T AT00116947T ATE346644T1 AT E346644 T1 ATE346644 T1 AT E346644T1 AT 00116947 T AT00116947 T AT 00116947T AT 00116947 T AT00116947 T AT 00116947T AT E346644 T1 ATE346644 T1 AT E346644T1
Authority
AT
Austria
Prior art keywords
housing
pharmaceutical agent
microneedles
substance
microns
Prior art date
Application number
AT00116947T
Other languages
English (en)
Inventor
Zeil B Rosenberg
Original Assignee
Becton Dickinson Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Co filed Critical Becton Dickinson Co
Application granted granted Critical
Publication of ATE346644T1 publication Critical patent/ATE346644T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/20Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
AT00116947T 1999-09-22 2000-08-07 Vorrichtung zur transdermalen verabreichung von einer substanz ATE346644T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/401,452 US6623457B1 (en) 1999-09-22 1999-09-22 Method and apparatus for the transdermal administration of a substance

Publications (1)

Publication Number Publication Date
ATE346644T1 true ATE346644T1 (de) 2006-12-15

Family

ID=23587826

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00116947T ATE346644T1 (de) 1999-09-22 2000-08-07 Vorrichtung zur transdermalen verabreichung von einer substanz

Country Status (9)

Country Link
US (4) US6623457B1 (de)
EP (1) EP1086718B1 (de)
JP (1) JP2001149485A (de)
AT (1) ATE346644T1 (de)
AU (1) AU778234B2 (de)
CA (1) CA2315469C (de)
DE (1) DE60032082T2 (de)
ES (1) ES2273639T3 (de)
SG (1) SG92728A1 (de)

Families Citing this family (300)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US6611707B1 (en) 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6641591B1 (en) 1999-08-26 2003-11-04 John H. Shadduck Instruments and techniques for controlled removal of epidermal layers
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US6331266B1 (en) * 1999-09-29 2001-12-18 Becton Dickinson And Company Process of making a molded device
US20020156453A1 (en) * 1999-10-14 2002-10-24 Pettis Ronald J. Method and device for reducing therapeutic dosage
US8465468B1 (en) * 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
US20020095134A1 (en) * 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
US6494865B1 (en) * 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly
EP1416980A2 (de) * 1999-12-30 2004-05-12 Redeon, Inc. Stapelbare mikronadel-systeme
US6595947B1 (en) * 2000-05-22 2003-07-22 Becton, Dickinson And Company Topical delivery of vaccines
WO2001093930A1 (en) * 2000-06-02 2001-12-13 The University Of Utah Research Foundation Active needle devices with integrated functionality
US20040175360A1 (en) * 2000-06-29 2004-09-09 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
AU2001293460A1 (en) 2000-10-05 2002-04-15 Thomas Marsoner Medical injection device
US6821281B2 (en) 2000-10-16 2004-11-23 The Procter & Gamble Company Microstructures for treating and conditioning skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
WO2002045771A2 (en) * 2000-11-09 2002-06-13 Biovalve Technologies, Inc. Microneedle adapter
WO2002064193A2 (en) * 2000-12-14 2002-08-22 Georgia Tech Research Corporation Microneedle devices and production thereof
US7850663B2 (en) 2001-01-12 2010-12-14 Becton, Dickinson And Company Medicament microdevice delivery system, cartridge and method of use
WO2002074336A2 (en) * 2001-02-23 2002-09-26 Glaxosmithkline Biologicals S.A. Influenza vaccine formulations for intradermal delivery
US6663820B2 (en) * 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
EP1381423A1 (de) * 2001-04-13 2004-01-21 Becton, Dickinson and Company Verfahren und vorrichtung zur intradermale abgabe von substanzen für systemischer absorption
IL158480A0 (en) * 2001-04-20 2004-05-12 Alza Corp Microprojection array having a beneficial agent containing coating
AU2007203302B2 (en) * 2001-04-20 2010-07-01 Alza Corporation Microprojection array immunization patch and method
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
CA2445120A1 (en) * 2001-04-27 2002-11-07 Glaxosmithkline Biologicals Sa Devices for the intradermal administration of influenza vaccines
EP1416986A4 (de) * 2001-06-29 2005-12-14 Becton Dickinson Co Intradermale freisetzung von vakzinen und gentherapeutischen mitteln mit einer mikrokanüle
US20060018877A1 (en) * 2001-06-29 2006-01-26 Mikszta John A Intradermal delivery of vacccines and therapeutic agents
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US20040087992A1 (en) * 2002-08-09 2004-05-06 Vladimir Gartstein Microstructures for delivering a composition cutaneously to skin using rotatable structures
US6830562B2 (en) 2001-09-27 2004-12-14 Unomedical A/S Injector device for placing a subcutaneous infusion set
RU2314760C2 (ru) * 2001-12-20 2008-01-20 Алза Корпорейшн Микровыступы, пробивающие кожу, имеющие средство регулирования глубины пробивки
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7047070B2 (en) * 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US7115108B2 (en) * 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
EP1501567B1 (de) 2002-05-06 2018-02-21 Becton, Dickinson and Company Vorrichtung zur kontrolle der arzneimittel-pharmakokinetik
US20060264886A9 (en) * 2002-05-06 2006-11-23 Pettis Ronald J Method for altering insulin pharmacokinetics
AU2003251831B2 (en) 2002-07-19 2009-06-11 3M Innovative Properties Company Microneedle devices and microneedle delivery apparatus
US20040082934A1 (en) * 2002-08-30 2004-04-29 Pettis Ronald J. Method of controlling pharmacokinetics of immunomodulatory compounds
US20040051019A1 (en) 2002-09-02 2004-03-18 Mogensen Lasse Wesseltoft Apparatus for and a method of adjusting the length of an infusion tube
AU2003277306A1 (en) * 2002-10-07 2004-05-04 Biovalve Technologies, Inc. Microneedle array patch
DK200201823A (da) 2002-11-26 2004-05-27 Maersk Medical As Forbindelsesstykke for en slangeforbindelse
CA2524444A1 (en) * 2003-05-06 2004-11-25 Becton, Dickinson And Company A method for altering insulin pharmacokinetics
AU2004245051B2 (en) * 2003-06-02 2010-10-07 Becton, Dickinson And Company Medicament microdevice delivery system with a cartridge
EP1632263A4 (de) * 2003-06-10 2008-04-30 Medrx Co Ltd Verfahren zur herstellung einer auflagenbasis für die transdermale arzneimittelverabreichung, auflagenbasis für die transdermale arzneimittelverabreichung und nadel
JP2005021678A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベースの製造方法及び経皮投薬用パッドベース、並びに注射針
BRPI0412029A (pt) * 2003-06-30 2006-09-05 Alza Corp formulações para microprojeções revestidas contendo contra-ìons não-voláteis
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
CA2530996C (en) 2003-07-03 2013-05-07 Corium International, Inc. Wound dressing, ingredient delivery device and iv hold-down, and method relating to same
US7766902B2 (en) 2003-08-13 2010-08-03 Wisconsin Alumni Research Foundation Microfluidic device for drug delivery
US8353861B2 (en) * 2003-09-18 2013-01-15 Texmac, Inc. Applicator for applying functional substances into human skin
US20050089554A1 (en) * 2003-10-24 2005-04-28 Cormier Michel J. Apparatus and method for enhancing transdermal drug delivery
CA2552385C (en) * 2003-12-29 2013-07-23 3M Innovative Properties Company Medical devices and kits including same
CA2560840C (en) * 2004-03-24 2014-05-06 Corium International, Inc. Transdermal delivery device
KR101158939B1 (ko) 2004-03-26 2012-06-21 우노메디컬 에이/에스 주사세트를 위한 주사장치
US20050251095A1 (en) * 2004-05-07 2005-11-10 Giap Brandon C Improved medication injection device
WO2005112984A2 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
ES2650188T3 (es) * 2004-06-10 2018-01-17 3M Innovative Properties Company Dispositivo y kit de aplicación de parches
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
ES2463818T3 (es) 2004-08-16 2014-05-29 Functional Microstructures Limited Dispositivo que se aplicará a una barrera biológica
AR050608A1 (es) * 2004-08-19 2006-11-08 Alza Corp Aparato y metodo para administracion transdermica de factores de crecimiento endotelial vascular
US7316665B2 (en) * 2004-08-25 2008-01-08 Becton, Dickinson And Company Method and device for the delivery of a substance including a covering
AU2005306426B2 (en) * 2004-11-18 2011-04-28 3M Innovative Properties Company Masking method for coating a microneedle array
WO2006055795A1 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Low-profile microneedle array applicator
JP5015787B2 (ja) 2004-11-18 2012-08-29 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイの接触コーティング法
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
WO2006055802A1 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Microneedle array applicator and retainer
US20080307849A1 (en) * 2004-11-26 2008-12-18 Agency For Science, Technology And Research Method And Apparatus For Forming Microstructures
CA2589693A1 (en) 2004-12-10 2006-06-15 Unomedical A/S Inserter
WO2006064271A1 (en) * 2004-12-17 2006-06-22 Functional Microstructures Limited Microneedle device for transdermal transport of fluid
US20060204562A1 (en) * 2005-02-16 2006-09-14 Cormier Michel J Microprojection arrays with improved biocompatibility
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
EP1871457B1 (de) 2005-04-11 2012-05-02 Infotonics Technology Center, Inc. Blutüberwachungssysteme und verfahren dafür
WO2006115502A1 (en) * 2005-04-25 2006-11-02 Giap, Brandon, C. Improved medication injection device
US8043250B2 (en) * 2005-05-18 2011-10-25 Nanomed Devices, Inc. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
AU2006261898B2 (en) * 2005-06-27 2011-11-03 3M Innovative Properties Company Microneedle array applicator device
EP1896115B2 (de) * 2005-06-27 2020-01-22 3M Innovative Properties Company Mikronadelkartuschenanordnung
US20080214952A1 (en) * 2005-07-11 2008-09-04 Jose Mir Replaceable Cartridge for Allergy Testing System
CN101912288A (zh) * 2005-09-02 2010-12-15 因特赛尔美国公司 经皮递送疫苗和透皮递送药物的装置及其应用
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US9358033B2 (en) * 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US9486274B2 (en) 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
ATE480278T1 (de) 2005-09-12 2010-09-15 Unomedical As Einfürungssystem für ein infusionsset mit einem ersten und zweiten federeinheit
GB0520757D0 (en) * 2005-10-12 2005-11-23 Vuppalapati Gunasekar Delivery device
WO2007047539A2 (en) * 2005-10-14 2007-04-26 Medtronic, Inc. Localized delivery to the lymphatic system
US9248317B2 (en) 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
CA2631882C (en) * 2005-12-08 2015-02-10 Nanopass Technologies Ltd. Microneedle adapter for dosed drug delivery devices
USD655807S1 (en) 2005-12-09 2012-03-13 Unomedical A/S Medical device
DE602006019153D1 (de) 2005-12-23 2011-02-03 Unomedical As Injektionsvorrichtung
US8048089B2 (en) 2005-12-30 2011-11-01 Edge Systems Corporation Apparatus and methods for treating the skin
US9610459B2 (en) 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
WO2007098771A2 (en) 2006-02-28 2007-09-07 Unomedical A/S Inserter for infusion part and infusion part provided with needle protector
US10172644B2 (en) 2006-03-29 2019-01-08 Edge Systems Llc Devices, systems and methods for treating the skin
US9566088B2 (en) 2006-03-29 2017-02-14 Edge Systems Llc Devices, systems and methods for treating the skin
WO2014151104A1 (en) 2013-03-15 2014-09-25 Edge Systems Llc Devices, systems and methods for treating the skin
WO2007124411A1 (en) * 2006-04-20 2007-11-01 3M Innovative Properties Company Device for applying a microneedle array
US20070265570A1 (en) * 2006-04-27 2007-11-15 Gerut Zachary E Device and method for treating skin prior to performing surgery
US20070276318A1 (en) * 2006-05-26 2007-11-29 Mit, Llp Iontosonic-microneedle applicator apparatus and methods
US20070276330A1 (en) * 2006-05-28 2007-11-29 Beck Patricia A Microneedles and methods of fabricating thereof
US20070276425A1 (en) * 2006-05-29 2007-11-29 Stanley Kim Painless Blood Sampling Lancet with Bundled Multiple Thin Needles
US20070282246A1 (en) * 2006-06-05 2007-12-06 Mit, Llp Iontosonic-microneedle biosensor apparatus and methods
US8439838B2 (en) 2006-06-07 2013-05-14 Unomedical A/S Inserter for transcutaneous sensor
US8790311B2 (en) 2006-06-09 2014-07-29 Unomedical A/S Mounting pad
US20080015516A1 (en) * 2006-07-12 2008-01-17 Nanopass Technologies Ltd. Microneedle Devices With Controlled Uncapping
US8012566B2 (en) * 2006-07-12 2011-09-06 Hewlett-Packard Development Company, L.P. Microneedles formed by electroplating and selectively releasing temperature sensitive layers
US8250729B2 (en) * 2006-07-12 2012-08-28 University Of Utah Research Foundation 3D fabrication of needle tip geometry and knife blade
KR100886633B1 (ko) * 2006-07-14 2009-03-04 호남석유화학 주식회사 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치
JP2008029710A (ja) * 2006-07-31 2008-02-14 Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai マイクロニードル型パッチ及びその製造方法
CN101500627B (zh) 2006-08-02 2012-03-14 优诺医疗有限公司 套管和输送装置
WO2008042902A2 (en) 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
EP1917990A1 (de) 2006-10-31 2008-05-07 Unomedical A/S Infusionsset
US20080114340A1 (en) * 2006-11-01 2008-05-15 Biotex, Inc. System and method for reducing photon scatter in dermal tissue
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
US8523926B2 (en) * 2007-01-19 2013-09-03 Joseph Neev Devices and methods for generation of subsurface microdisruptions for biomedical applications
US10588694B1 (en) 2007-01-19 2020-03-17 Joseph Neev Devices and methods for generation of subsurface micro-disruptions for biomedical applications
CA2676221C (en) 2007-01-22 2016-12-20 Corium International, Inc. Applicators for microneedles
EP2146689B1 (de) 2007-04-16 2020-08-12 Corium, Inc. Einen wirkstoff enthaltende lösungsmittel-gegossene mikronadelanordnungen
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EA020953B1 (ru) * 2007-06-14 2015-03-31 Краселл Свитзерленд Аг Внутрикожная вакцина против гриппа
AU2008266382B2 (en) 2007-06-20 2013-06-27 Unomedical A/S A catheter and a method and an apparatus for making such catheter
KR20100049574A (ko) 2007-07-03 2010-05-12 우노메디컬 에이/에스 이중안정의 평형상태를 갖춘 주입기
EP2173431A4 (de) * 2007-07-09 2013-06-12 Apogee Technology Inc Immunstimulierende polyphosphazen-verbindungen zur intradermalen immunisierung
ES2360842T3 (es) 2007-07-10 2011-06-09 Unomedical A/S Dispositivo de inserción con dos muelles.
WO2009010396A1 (en) 2007-07-18 2009-01-22 Unomedical A/S Insertion device with pivoting action
JP5587775B2 (ja) * 2007-07-21 2014-09-10 キム、スタンリー ランセットシステム
US8328720B2 (en) 2007-08-10 2012-12-11 Infotonics Technology Center, Inc. MEMS interstitial prothrombin time test
JP5223278B2 (ja) * 2007-09-27 2013-06-26 凸版印刷株式会社 マイクロニードル製造方法
EP2205169B1 (de) * 2007-09-28 2016-11-16 The Queen's University of Belfast Abgabevorrichtung und- verfahren
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
EP2240099B1 (de) 2008-01-04 2018-02-21 Edge Systems LLC Vorrichtung zur hautbehandlung
US9056193B2 (en) 2008-01-29 2015-06-16 Edge Systems Llc Apparatus and method for treating the skin
RU2010137844A (ru) 2008-02-13 2012-03-20 Уномедикал А/С (Dk) Уплотнение между канюльной частью и путем прохождения текучей среды
WO2009103759A1 (en) 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
US9408971B2 (en) * 2008-03-31 2016-08-09 Covidien Lp Self-capping syringe assembly with one-way valve
WO2009130926A1 (ja) * 2008-04-22 2009-10-29 南部化成株式会社 経皮投薬方法、ニードル形成体及び経皮投薬装置
US10543123B2 (en) 2008-04-28 2020-01-28 Joseph Neev Devices and methods for generation of subsurface micro-disruptions for opthalmic surgery and opthalmic applications
JP5476062B2 (ja) * 2008-07-25 2014-04-23 南部化成株式会社 経皮投薬デバイス
US8986250B2 (en) 2008-08-01 2015-03-24 Wisconsin Alumni Research Foundation Drug delivery platform utilizing hydrogel pumping mechanism
US8795259B2 (en) 2008-08-01 2014-08-05 Wisconsin Alumni Research Foundation Drug delivery platform incorporating hydrogel pumping mechanism with guided fluid flow
US9072799B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8788211B2 (en) 2008-10-31 2014-07-22 The Invention Science Fund I, Llc Method and system for comparing tissue ablation or abrasion data to data related to administration of a frozen particle composition
US8603495B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US9072688B2 (en) 2008-10-31 2015-07-07 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8545855B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US9060934B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8221480B2 (en) 2008-10-31 2012-07-17 The Invention Science Fund I, Llc Compositions and methods for biological remodeling with frozen particle compositions
US8762067B2 (en) 2008-10-31 2014-06-24 The Invention Science Fund I, Llc Methods and systems for ablation or abrasion with frozen particles and comparing tissue surface ablation or abrasion data to clinical outcome data
US8725420B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8793075B2 (en) 2008-10-31 2014-07-29 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US20100111857A1 (en) 2008-10-31 2010-05-06 Boyden Edward S Compositions and methods for surface abrasion with frozen particles
US8731841B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9050070B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8849441B2 (en) 2008-10-31 2014-09-30 The Invention Science Fund I, Llc Systems, devices, and methods for making or administering frozen particles
US8409376B2 (en) 2008-10-31 2013-04-02 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8721583B2 (en) 2008-10-31 2014-05-13 The Invention Science Fund I, Llc Compositions and methods for surface abrasion with frozen particles
US8798932B2 (en) 2008-10-31 2014-08-05 The Invention Science Fund I, Llc Frozen compositions and methods for piercing a substrate
US9050317B2 (en) 2008-10-31 2015-06-09 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9060931B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US8545856B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for delivery of frozen particle adhesives
US8545857B2 (en) 2008-10-31 2013-10-01 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US8603494B2 (en) 2008-10-31 2013-12-10 The Invention Science Fund I, Llc Compositions and methods for administering compartmentalized frozen particles
US8731840B2 (en) 2008-10-31 2014-05-20 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US8551505B2 (en) 2008-10-31 2013-10-08 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
US9060926B2 (en) 2008-10-31 2015-06-23 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with frozen particles
EP2347788A4 (de) * 2008-11-17 2012-05-16 Yoichi Inaba Einfaches gerät zur behandlung von trichophytosis unguium
KR20190064676A (ko) * 2008-11-18 2019-06-10 쓰리엠 이노베이티브 프로퍼티즈 컴파니 중공 마이크로니들 어레이
MX2011005735A (es) 2008-12-22 2011-06-21 Unomedical As Dispositivo medico que comprende una almohadilla de adhesivo.
FI20095433A0 (fi) * 2009-04-20 2009-04-20 Valtion Teknillinen Mikroneula
EP2451367B1 (de) 2009-07-08 2020-01-22 Edge Systems Corporation Vorrichtungen zur hautbehandlung mithilfe zeitgesteuert freigesetzter substanzen
JP2013500099A (ja) 2009-07-30 2013-01-07 ウノメディカル・アー/エス 水平方向の可動部材を備えた挿入デバイス
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
JP2013500805A (ja) 2009-08-07 2013-01-10 ウノメディカル・アー/エス センサおよび1つまたは複数のカニューレを有する投与装置
US8088108B2 (en) * 2009-08-22 2012-01-03 Joseph Wayne Kraft Rapid local anesthesia injection cone
US8409147B2 (en) * 2009-08-22 2013-04-02 Joseph Wayne Kraft Rapid local anesthesia linear injection device
CA2773915A1 (en) * 2009-09-17 2011-04-14 Zipline Medical, Inc. Rapid closing surgical closure device
US10159825B2 (en) 2009-09-17 2018-12-25 Zipline Medical, Inc. Rapid closing surgical closure device
AU2010313487A1 (en) 2009-10-26 2012-05-24 Emkinetics, Inc. Method and apparatus for electromagnetic stimulation of nerve, muscle, and body tissues
DE102009046581A1 (de) * 2009-11-10 2011-05-12 Robert Bosch Gmbh Herstellungsverfahren für eine poröse Mikronadelanordnung und entsprechende poröse Mikronadelanordnung und entsprechender Substratverbund
JP5785559B2 (ja) 2009-12-16 2015-09-30 クロンテック ファーマ アーベー 注射針および注射装置
CA2689400C (en) * 2009-12-30 2023-01-10 Kenneth W. Adams Therapeutic agent delivery apparatus and process
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
US8328757B2 (en) * 2010-01-08 2012-12-11 Wisconsin Alumni Research Foundation Bladder arrangement for microneedle-based drug delivery device
US9327105B2 (en) 2010-03-26 2016-05-03 Itrace Biomedical Inc. Active transdermal drug delivery system and the method thereof
EP2552513B1 (de) 2010-03-30 2014-03-19 Unomedical A/S Medizinische vorrichtung
US8439945B2 (en) 2010-05-03 2013-05-14 Zipline Medical, Inc. Methods for biopsying tissue
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル, インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
CN103002844B (zh) 2010-06-14 2016-08-31 奇普林医药公司 用于抑制疤痕形成的方法和装置
EP2600901B1 (de) 2010-08-06 2019-03-27 ModernaTX, Inc. Pharmazeutische zusammensetzungen enthaltenbearbeitete nukleinsäuren und ihre medizinische verwendung
EP2433663A1 (de) 2010-09-27 2012-03-28 Unomedical A/S Einführsystem
ES2737960T3 (es) 2010-10-01 2020-01-17 Modernatx Inc Nucleósidos, nucleótidos y ácidos nucleicos modificados y sus usos
EP2436412A1 (de) 2010-10-04 2012-04-04 Unomedical A/S Sprinklerkanüle
US10441767B2 (en) 2010-10-27 2019-10-15 Asti Corporation Jig for microneedle array placement and microneedle array device
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
WO2012071281A2 (en) * 2010-11-23 2012-05-31 The Regents Of The University Of California Low-pressure biolistic barrels
US10244981B2 (en) 2011-03-30 2019-04-02 SensiVida Medical Technologies, Inc. Skin test image analysis apparatuses and methods thereof
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US8636696B2 (en) 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
CN103717249B (zh) 2011-06-15 2017-03-22 克洛恩泰克制药股份公司 注射针和装置
CN103764668B (zh) 2011-07-09 2016-08-17 加利福尼亚大学董事会 白血病干细胞靶向配体及应用方法
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
US9700245B2 (en) 2011-09-23 2017-07-11 Itrace Biomedical Inc. Transdermal analyte extraction and detection system and the method thereof
EP3682905B1 (de) 2011-10-03 2021-12-01 ModernaTX, Inc. Modifizierte nukleoside, nukleotide und nukleinsäuren und verwendungen davon
CN103957962B (zh) 2011-10-05 2017-07-07 犹诺医药有限公司 用于同时插入多个经皮部分的插入物
EP2578190A1 (de) * 2011-10-07 2013-04-10 Sanofi-Aventis Deutschland GmbH Intraokulare Injektionsvorrichtung
EP2583715A1 (de) 2011-10-19 2013-04-24 Unomedical A/S Infusionsschlauchsystem und Herstellungsverfahren
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US8323313B1 (en) 2011-11-01 2012-12-04 Zipline Medical, Inc. Surgical incision and closure apparatus with integrated force distribution
US10123801B2 (en) 2011-11-01 2018-11-13 Zipline Medical, Inc. Means to prevent wound dressings from adhering to closure device
US9050086B2 (en) 2011-11-01 2015-06-09 Zipline Medical, Inc. Surgical incision and closure apparatus
US10123800B2 (en) 2011-11-01 2018-11-13 Zipline Medical, Inc. Surgical incision and closure apparatus with integrated force distribution
US9561034B2 (en) 2011-11-01 2017-02-07 Zipline Medical, Inc. Surgical incision and closure apparatus
EP2791160B1 (de) 2011-12-16 2022-03-02 ModernaTX, Inc. Modifizierte mrna zusammensetzungen
US10383835B2 (en) 2012-03-14 2019-08-20 The Regents Of The University Of California Treatment of inflammatory disorders in non-human mammals
AU2013243948A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins associated with human disease
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
CN104185475A (zh) * 2012-04-03 2014-12-03 谢拉杰克特股份有限公司 面颊给药的可溶微针阵列疫苗
WO2013171907A1 (ja) * 2012-05-18 2013-11-21 大勝 明 注射針、および、キット製剤
KR200466758Y1 (ko) 2012-06-01 2013-05-07 인싸이토(주) 경피내 주사기 모듈
JP6418544B2 (ja) * 2012-06-27 2018-11-07 コスメディ製薬株式会社 マイクロニードルパッチの保護離型シート
JP5903016B2 (ja) * 2012-06-27 2016-04-13 コスメディ製薬株式会社 マイクロニードルパッチの保護離型シート
WO2014064534A2 (en) 2012-10-05 2014-05-01 Chrontech Pharma Ab Injection needle, device, immunogenic compositions and method of use
EP4074834A1 (de) 2012-11-26 2022-10-19 ModernaTX, Inc. Am kettenende modifizierte rna
CA2896188C (en) 2012-12-21 2021-02-23 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
US10179239B2 (en) 2013-01-15 2019-01-15 Itrace Biomedical Inc. Personalized pain management treatments
US9710607B2 (en) 2013-01-15 2017-07-18 Itrace Biomedical Inc. Portable electronic therapy device and the method thereof
EP2957315B1 (de) * 2013-02-13 2019-11-13 Hisamitsu Pharmaceutical Co., Inc. Mikronadelarray
US10183156B2 (en) 2013-02-28 2019-01-22 Sorrento Therapeutics, Inc. Transdermal drug delivery device
WO2014132239A1 (en) 2013-02-28 2014-09-04 Kimberly-Clark Worldwide, Inc. Drug delivery device
US10245422B2 (en) 2013-03-12 2019-04-02 Corium International, Inc. Microprojection applicators and methods of use
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
EP2968751B1 (de) 2013-03-15 2022-11-30 Corium, Inc. Mehrfachberührungs-mikroprojektionsapplikatoren
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
CA2906541C (en) 2013-03-15 2022-06-21 Corium International, Inc. Microarray for delivery of therapeutic agent and methods of use
US10238812B2 (en) 2013-03-15 2019-03-26 Edge Systems Llc Skin treatment systems and methods using needles
AU2014233541B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US10736840B2 (en) 2013-09-03 2020-08-11 Georgia Tech Research Corporation Thermally stable vaccine formulations and microneedles
CA2926218A1 (en) 2013-10-03 2015-04-09 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
EP3089677B1 (de) 2014-01-05 2020-04-01 Zipline Medical, Inc. Instrumentierte wundverschlussvorrichtung
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
EP3132822B1 (de) * 2014-04-14 2018-10-31 Toppan Printing Co., Ltd. Injektionsvorrichtung
JP6566964B2 (ja) 2014-04-30 2019-08-28 ソレント・セラピューティクス・インコーポレイテッド 経皮的薬物送達装置および方法
CN106535979B (zh) 2014-04-30 2018-12-21 金伯利-克拉克环球有限公司 透皮药物递送设备的控制器部分和方法
CN106232172B (zh) 2014-04-30 2020-05-22 索伦托治疗有限公司 透皮药物递送设备的插座部分和方法
KR101724655B1 (ko) * 2014-06-02 2017-04-13 주식회사 아모라이프사이언스 마이크로 니들 패치 및 그의 제조 방법
US9987427B1 (en) * 2014-06-24 2018-06-05 National Technology & Engineering Solutions Of Sandia, Llc Diagnostic/drug delivery “sense-respond” devices, systems, and uses thereof
US9907941B2 (en) 2014-07-21 2018-03-06 The Cleveland Clinic Foundation Convection enhanced delivery device and system
US9968765B2 (en) 2014-07-21 2018-05-15 The Cleveland Clinic Foundation Convection enhanced delivery device and system
KR101636775B1 (ko) * 2014-08-19 2016-07-08 아주대학교산학협력단 부위마취 장치 및 방법
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
JP5931155B2 (ja) * 2014-09-30 2016-06-08 日本写真印刷株式会社 マイクロニードルシートの梱包体及びその製造方法
JP6906885B2 (ja) 2014-11-14 2021-07-21 ロレアル しわを減少させるためのマイクロニードルシート
US10179229B2 (en) 2014-12-23 2019-01-15 Edge Systems Llc Devices and methods for treating the skin using a porous member
EP4324414A3 (de) 2014-12-23 2024-05-01 HydraFacial LLC Vorrichtungen und verfahren zur hautbehandlung mit einem rollball oder einem dochtelement
CN104922791B (zh) * 2015-05-26 2018-10-26 上海交通大学 无创针灸贴片及其制备方法
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
EP3319573A4 (de) 2015-07-08 2019-01-23 Edge Systems LLC Vorrichtungen, systeme und zusammensetzungen zur förderung des haarwachstums
WO2017151806A1 (en) 2016-03-01 2017-09-08 Kitotech Medical, Inc. Microstructure-based systems, apparatus, and methods for wound closure
WO2018081795A1 (en) 2016-10-31 2018-05-03 Zipline Medical, Inc. Systems and methods for monitoring physical therapy of the knee and other joints
US11241563B2 (en) * 2016-12-22 2022-02-08 Johnson & Johnson Consumer Inc. Microneedle arrays and methods for making and using
US11235132B2 (en) * 2016-12-22 2022-02-01 Ohio State Innovation Foundation Interpenetrating microstructures for nanochannel-based cargo delivery
US11065428B2 (en) 2017-02-17 2021-07-20 Allergan, Inc. Microneedle array with active ingredient
WO2019033362A1 (zh) * 2017-08-17 2019-02-21 深圳华迈兴微医疗科技有限公司 一种采血装置及其控制设备
CN109394236B (zh) * 2017-08-17 2022-04-01 李泉 一种采血装置及其控制设备
JPWO2019059265A1 (ja) * 2017-09-20 2019-12-19 シンクランド株式会社 マイクロニードルシート及びマイクロニードルシートの製造方法
TWI657842B (zh) * 2017-10-27 2019-05-01 研能科技股份有限公司 人體胰島素注入之供液裝置
TWI666036B (zh) * 2017-10-27 2019-07-21 研能科技股份有限公司 穿戴式人體胰島素注入供液裝置
CA3101595A1 (en) 2018-06-29 2020-01-02 Johnson & Johnson Consumer Inc. Three-dimensional microfluidics devices for the delivery of actives
GB2574074B (en) 2018-07-27 2020-05-20 Mclaren Applied Tech Ltd Time synchronisation
GB2588236B (en) 2019-10-18 2024-03-20 Mclaren Applied Ltd Gyroscope bias estimation
KR20220097412A (ko) * 2019-10-24 2022-07-07 자닌 홉킨스 어플리케이터 장치 및 사용 방법
WO2021207705A1 (en) * 2020-04-09 2021-10-14 Carnegie Mellon University Hybrid microneedle arrays
CN112869871B (zh) * 2021-01-11 2022-10-14 杭州维纳安可医疗科技有限责任公司 消融装置及其控制方法、装置、系统、存储介质
US20240090908A1 (en) * 2021-01-22 2024-03-21 Sorrento Therapeutics, Inc. Device for microliter-scale lymphatic delivery of coronavirus vaccines and methods of use thereof
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
KR102577073B1 (ko) * 2021-04-27 2023-09-11 주식회사 이엘홀딩스 마이크로 니들을 이용한 문신 패치
USD1016615S1 (en) 2021-09-10 2024-03-05 Hydrafacial Llc Container for a skin treatment device
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11510602B1 (en) 2021-11-08 2022-11-29 Satio, Inc. Dermal patch for collecting a physiological sample
WO2023159181A1 (en) 2022-02-18 2023-08-24 Kitotech Medical, Inc. Force modulating deep skin staples and instruments
WO2023193010A1 (en) 2022-04-01 2023-10-05 The Regents Of The University Of California Methods of improving cancer immunotherapy
WO2023211820A1 (en) 2022-04-29 2023-11-02 Colgate-Palmolive Company Personal care compositions

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1699012A (en) * 1927-11-22 1929-01-15 Joseph S Naylor Stock and poultry marker
US3072122A (en) * 1959-01-15 1963-01-08 Rosenthal Sol Roy Package for transcutaneous injection
FR1584474A (de) 1968-02-20 1969-12-26
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
DE2513467C3 (de) * 1975-03-26 1979-10-31 Siemens Ag, 1000 Berlin Und 8000 Muenchen Gerät zur Infusion von Flüssigkeiten in den menschlichen oder tierischen Körper
IT1202218B (it) * 1985-05-21 1989-02-02 Mario Aluigi Piastre di derivazione multi-aghi per uso mesoterapico e relative custodie salva punte
EP0429842B1 (de) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5312456A (en) 1991-01-31 1994-05-17 Carnegie Mellon University Micromechanical barb and method for making the same
JPH09509087A (ja) * 1994-02-28 1997-09-16 ノボ ノルディスク アクティーゼルスカブ 針ユニット
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
WO1996037256A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical patch for enhancing the delivery of compounds through the skin
DE19525607A1 (de) * 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
AU3399197A (en) 1996-06-18 1998-01-07 Alza Corporation Device for enhancing transdermal agent delivery or sampling
DK0921840T3 (da) 1996-07-03 2003-09-22 Altea Therapeutics Corp Multipel mekanisk mikroperforering af hud eller slimhinde
US6004295A (en) 1997-06-26 1999-12-21 An-Go-Gen Inc. Catheters
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
WO2000035530A1 (en) * 1998-12-18 2000-06-22 Minimed Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
EP1187653B1 (de) * 1999-06-04 2010-03-31 Georgia Tech Research Corporation Vorrichtungen zur vergrösserten penetration von mikronadeln in biologischen hautschichten
US6256533B1 (en) * 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US6623457B1 (en) * 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance

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US20080287864A1 (en) 2008-11-20
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US20060047243A1 (en) 2006-03-02
AU5352800A (en) 2001-03-29
DE60032082D1 (de) 2007-01-11
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AU778234B2 (en) 2004-11-25
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US20030199812A1 (en) 2003-10-23
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