ATE257714T1 - Einschluss komplexe von aryl-heterokyhlishe salzen - Google Patents

Einschluss komplexe von aryl-heterokyhlishe salzen

Info

Publication number
ATE257714T1
ATE257714T1 AT97907246T AT97907246T ATE257714T1 AT E257714 T1 ATE257714 T1 AT E257714T1 AT 97907246 T AT97907246 T AT 97907246T AT 97907246 T AT97907246 T AT 97907246T AT E257714 T1 ATE257714 T1 AT E257714T1
Authority
AT
Austria
Prior art keywords
heterocyhlic
aryl
salts
include complexes
complexes
Prior art date
Application number
AT97907246T
Other languages
English (en)
Inventor
Kevin Charles Johnson
Yesook Kim
Ravi Mysore Shanker
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE257714T1 publication Critical patent/ATE257714T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Soil Conditioners And Soil-Stabilizing Materials (AREA)
  • Seasonings (AREA)
  • Machine Translation (AREA)
AT97907246T 1996-05-07 1997-04-01 Einschluss komplexe von aryl-heterokyhlishe salzen ATE257714T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1920496P 1996-05-07 1996-05-07
PCT/IB1997/000321 WO1997041896A2 (en) 1996-05-07 1997-04-01 Inclusion complexes of aryl-heterocyclic salts

Publications (1)

Publication Number Publication Date
ATE257714T1 true ATE257714T1 (de) 2004-01-15

Family

ID=21791976

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97907246T ATE257714T1 (de) 1996-05-07 1997-04-01 Einschluss komplexe von aryl-heterokyhlishe salzen

Country Status (47)

Country Link
US (2) US6232304B1 (de)
EP (1) EP0900088B1 (de)
JP (1) JP3579060B2 (de)
KR (1) KR20000010823A (de)
CN (1) CN1216923A (de)
AP (1) AP796A (de)
AR (2) AR007002A1 (de)
AT (1) ATE257714T1 (de)
AU (1) AU713711B2 (de)
BG (3) BG64474B1 (de)
BR (1) BR9709213A (de)
CA (1) CA2251912C (de)
CO (1) CO4600677A1 (de)
CZ (1) CZ297847B6 (de)
DE (1) DE69727218T2 (de)
DK (1) DK0900088T3 (de)
DZ (1) DZ2220A1 (de)
EA (1) EA001731B1 (de)
EG (1) EG24135A (de)
ES (1) ES2212809T3 (de)
GE (1) GEP20074185B (de)
GT (1) GT199700044A (de)
HN (1) HN1997000039A (de)
HR (1) HRP970237B1 (de)
HU (1) HU222451B1 (de)
ID (1) ID16866A (de)
IL (1) IL126546A (de)
IS (1) IS2524B (de)
MA (1) MA24172A1 (de)
ME (1) ME00880B (de)
MY (1) MY121999A (de)
NO (1) NO324373B1 (de)
NZ (1) NZ332220A (de)
OA (1) OA10907A (de)
PL (1) PL189324B1 (de)
PT (1) PT900088E (de)
RS (1) RS49532B (de)
SA (1) SA97180024B1 (de)
SI (1) SI0900088T1 (de)
SK (1) SK282032B6 (de)
TN (1) TNSN97075A1 (de)
TR (1) TR199802231T2 (de)
TW (1) TW514529B (de)
UA (1) UA57734C2 (de)
UY (1) UY24544A1 (de)
WO (1) WO1997041896A2 (de)
ZA (1) ZA973874B (de)

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UA57734C2 (uk) * 1996-05-07 2003-07-15 Пфайзер Інк. Комплекси включення арилгетероциклічних солей
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US6706721B1 (en) 1998-04-29 2004-03-16 Osi Pharmaceuticals, Inc. N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
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JP4503724B2 (ja) * 1999-05-10 2010-07-14 栄研化学株式会社 ホタルルシフェリンの安定化方法
US7087613B2 (en) 1999-11-11 2006-08-08 Osi Pharmaceuticals, Inc. Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
UA74803C2 (uk) 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
US6884885B2 (en) 2000-12-21 2005-04-26 Cerestar Holding B.V. Production of cyclodextrin complexes
US7034013B2 (en) * 2001-03-20 2006-04-25 Cydex, Inc. Formulations containing propofol and a sulfoalkyl ether cyclodextrin
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US20040048876A1 (en) * 2002-02-20 2004-03-11 Pfizer Inc. Ziprasidone composition and synthetic controls
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SI1542668T1 (sl) * 2002-08-20 2009-08-31 Bristol Myers Squibb Co Aripiprazol sestavljena formulacija in postopek
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JP2006506396A (ja) * 2002-10-31 2006-02-23 ファイザー・プロダクツ・インク 固体医薬の液体複合体
US20040142039A1 (en) * 2002-10-31 2004-07-22 Pfizer Inc Solid and semi-solid polymeric ionic conjugates
EP1418492B1 (de) 2002-11-05 2017-09-20 LG Electronics, Inc. Montageanordnung für einen berührungsaktiven Bildschirm für eine LCD-Anzeige
CN1255105C (zh) * 2002-12-17 2006-05-10 上海医药工业研究院 齐拉西酮及其盐的水溶性包合物及其制备方法
CA2528192A1 (en) * 2003-06-03 2005-02-24 Teva Pharmaceutical Industries Ltd Cristalline ziprasidone hcl and processes for preparation thereof
KR20090080143A (ko) * 2003-09-02 2009-07-23 화이자 프로덕츠 인크. 지프라시돈의 지속 방출형 투여 형태
KR20060103947A (ko) * 2003-12-08 2006-10-04 더 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 상승작용성 항암 조성물
EP1703898A2 (de) * 2003-12-31 2006-09-27 Alpharma, Inc. Formulierungen enthaltend ziprasidon
SI21703A (en) * 2004-01-14 2005-08-31 Lek Farmacevtska Druzba Dd Inclusion complexes of perindopril, procedure of their preparation, pharmaceutical compositions containing these complexes and their application in treatment of hypertensia
EP1744750A2 (de) 2004-05-06 2007-01-24 Sandoz AG Pharmazeutische zusammensetzung mit wasserabweisendem wirkstoff mit erhöhter löslichkeit
WO2006032957A1 (en) * 2004-05-26 2006-03-30 Pfizer Products Inc. In vitro predictive method
WO2005123086A2 (en) * 2004-06-11 2005-12-29 Dr. Reddy's Laboratories Ltd. Ziprasidone dosage form
CA2587710C (en) * 2004-11-16 2014-10-21 Elan Pharma International Ltd. Injectable nanoparticulate olanzapine formulations
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CA2598288A1 (en) * 2005-03-03 2006-09-14 Elan Pharma International Limited Nanoparticulate compositions of heterocyclic amide derivatives
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SI23610A (sl) 2011-01-13 2012-07-31 Diagen@d@o@o Nove adicijske soli ziprasidona postopek za njihovo pripravo in njihova uporaba v terapiji
CN102793701B (zh) * 2011-05-25 2014-12-17 上海医药工业研究院 卢拉西酮组合物
TW201332572A (zh) 2011-12-28 2013-08-16 Otsuka Pharma Co Ltd 具有經取代的β－環糊精之藥物製劑
AR094963A1 (es) 2013-03-04 2015-09-09 Ono Pharmaceutical Co Reacción de oxidación excelente en el índice de conversión
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UA57734C2 (uk) * 1996-05-07 2003-07-15 Пфайзер Інк. Комплекси включення арилгетероциклічних солей
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Also Published As

Publication number Publication date
IS4880A (is) 1998-10-27
KR20000010823A (ko) 2000-02-25
EP0900088A2 (de) 1999-03-10
NO985192L (no) 1998-11-06
SK282032B6 (sk) 2001-10-08
GEP20074185B (en) 2007-08-10
UA57734C2 (uk) 2003-07-15
SK150498A3 (en) 2000-01-18
ES2212809T3 (es) 2004-08-01
CA2251912C (en) 2003-06-03
US6232304B1 (en) 2001-05-15
HUP9902799A3 (en) 2000-12-28
IL126546A0 (en) 1999-08-17
HRP970237B1 (en) 2002-04-30
AR007002A1 (es) 1999-10-13
DE69727218T2 (de) 2004-11-18
UY24544A1 (es) 2000-09-29
US6399777B2 (en) 2002-06-04
EP0900088B1 (de) 2004-01-14
PL329928A1 (en) 1999-04-26
DE69727218D1 (de) 2004-02-19
CN1216923A (zh) 1999-05-19
EG24135A (en) 2008-08-06
TNSN97075A1 (fr) 2005-03-15
HU222451B1 (hu) 2003-07-28
WO1997041896A2 (en) 1997-11-13
DZ2220A1 (fr) 2002-12-03
BG64475B1 (bg) 2005-04-30
CO4600677A1 (es) 1998-05-08
CZ346198A3 (cs) 1999-09-15
MA24172A1 (fr) 1997-12-31
EA001731B1 (ru) 2001-08-27
AU1937297A (en) 1997-11-26
BG64474B1 (bg) 2005-04-30
CA2251912A1 (en) 1997-11-13
ID16866A (id) 1997-11-20
AP9700977A0 (en) 1997-07-31
PL189324B1 (pl) 2005-07-29
PT900088E (pt) 2004-04-30
RS49532B (sr) 2006-12-15
JP3579060B2 (ja) 2004-10-20
IS2524B (is) 2009-07-15
BR9709213A (pt) 1999-08-10
ZA973874B (en) 1998-11-06
AR045528A2 (es) 2005-11-02
BG102894A (en) 1999-09-30
IL126546A (en) 2001-01-28
TW514529B (en) 2002-12-21
NO985192D0 (no) 1998-11-06
TR199802231T2 (xx) 1999-02-22
HN1997000039A (es) 1997-06-26
SA97180024B1 (ar) 2005-12-24
YU17297A (sh) 1999-12-27
ME00880B (me) 2006-12-15
SI0900088T1 (en) 2004-04-30
OA10907A (en) 2001-10-26
HRP970237A2 (en) 1998-12-31
WO1997041896A3 (en) 1998-01-08
EA199800910A1 (ru) 1999-04-29
CZ297847B6 (cs) 2007-04-11
NZ332220A (en) 2000-03-27
HUP9902799A2 (hu) 1999-12-28
AU713711B2 (en) 1999-12-09
GT199700044A (es) 1998-10-02
DK0900088T3 (da) 2004-04-19
BG64475B2 (bg) 2005-04-30
NO324373B1 (no) 2007-10-01
US20010031756A1 (en) 2001-10-18
JPH11509866A (ja) 1999-08-31
MY121999A (en) 2006-03-31
AP796A (en) 1999-12-24

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