ATE250418T1 - Tabletten enthaltend eine kombination von glibenclamid und metformin - Google Patents

Tabletten enthaltend eine kombination von glibenclamid und metformin

Info

Publication number
ATE250418T1
ATE250418T1 AT98401781T AT98401781T ATE250418T1 AT E250418 T1 ATE250418 T1 AT E250418T1 AT 98401781 T AT98401781 T AT 98401781T AT 98401781 T AT98401781 T AT 98401781T AT E250418 T1 ATE250418 T1 AT E250418T1
Authority
AT
Austria
Prior art keywords
glibenclamide
metformin
combination
tablets containing
tablets
Prior art date
Application number
AT98401781T
Other languages
German (de)
English (en)
Inventor
Yves Bonhomme
Geoffrey Nicholson
Original Assignee
Merck Sante Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE250418(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sante Sas filed Critical Merck Sante Sas
Application granted granted Critical
Publication of ATE250418T1 publication Critical patent/ATE250418T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98401781T 1998-07-15 1998-07-15 Tabletten enthaltend eine kombination von glibenclamid und metformin ATE250418T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98401781A EP0974356B1 (en) 1998-07-15 1998-07-15 Tablets comprising a combination of metformin and glibenclamide

Publications (1)

Publication Number Publication Date
ATE250418T1 true ATE250418T1 (de) 2003-10-15

Family

ID=8235441

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98401781T ATE250418T1 (de) 1998-07-15 1998-07-15 Tabletten enthaltend eine kombination von glibenclamid und metformin

Country Status (27)

Country Link
US (2) US6303146B1 (OSRAM)
EP (4) EP0974356B1 (OSRAM)
JP (2) JP2002520371A (OSRAM)
KR (2) KR20040053177A (OSRAM)
CN (2) CN1146427C (OSRAM)
AP (1) AP1450A (OSRAM)
AR (2) AR013052A1 (OSRAM)
AT (1) ATE250418T1 (OSRAM)
AU (2) AU753604B2 (OSRAM)
BR (1) BR9906600A (OSRAM)
CA (1) CA2303537C (OSRAM)
DE (1) DE69818444T2 (OSRAM)
DK (1) DK0974356T3 (OSRAM)
DZ (1) DZ2846A1 (OSRAM)
ES (1) ES2206868T3 (OSRAM)
ID (1) ID25784A (OSRAM)
MA (1) MA24930A1 (OSRAM)
MY (1) MY129552A (OSRAM)
NZ (1) NZ503248A (OSRAM)
OA (1) OA11400A (OSRAM)
PT (1) PT974356E (OSRAM)
RU (2) RU2226396C2 (OSRAM)
SI (1) SI0974356T1 (OSRAM)
TW (2) TWI245632B (OSRAM)
UY (1) UY25611A1 (OSRAM)
WO (1) WO2000003742A2 (OSRAM)
ZA (1) ZA200001159B (OSRAM)

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US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
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US8206753B2 (en) * 2001-06-20 2012-06-26 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
CN1270724C (zh) 2001-07-30 2006-08-23 三菱制药株式会社 餐后高血糖改善剂
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
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US7183321B2 (en) * 2001-12-17 2007-02-27 Bristol-Myers Squibb Company Antidiabetic formulation and method
DE60219963T2 (de) * 2002-01-25 2008-02-07 Laboratorios Silanes, S.A. De C.V. Pharmazeutische zusammensetzung, die zur glukosekontrolle im blut von patienten mit diabetes typ 2 eingesetzt wird
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US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
US20030219482A1 (en) * 2002-03-21 2003-11-27 Chaudhari Sunil Sudhakar Multiparticulate compositions for once-a-day administration
AU2003246791A1 (en) 2002-04-09 2003-10-20 Flamel Technologies Oral suspension of amoxicillin capsules
PT1492511E (pt) 2002-04-09 2009-04-09 Flamel Tech Sa Formulação farmacêutica oral na forma de suspensão aquosa de microcápsulas para libertação modificada de princípio(s) activo(s)
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CN1729005A (zh) * 2002-11-15 2006-02-01 兰贝克赛实验室有限公司 含双胍－磺酰脲类组合的药物剂型
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation
TW200507875A (en) * 2003-04-15 2005-03-01 Chugai Pharmaceutical Co Ltd Remedy for diabetes
US20060121108A1 (en) * 2004-12-02 2006-06-08 Prasad C K System and method for producing a directly compressible, high-potency formulation of metformin hydrochloride
CN100341495C (zh) * 2004-12-29 2007-10-10 三九医药股份有限公司 格列本脲固体分散体、口服组合物及其制备方法
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
UY29445A1 (es) * 2005-03-30 2006-10-02 Generex Pharm Inc Composiciones para la transmisión transmucosa oral de la metformina
US8529537B2 (en) * 2005-08-05 2013-09-10 Kimberly-Clark Worldwide, Inc. Absorbent article with enclosures
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
EP2452683A3 (en) 2006-06-26 2012-08-22 Amgen Inc. Methods for treating atherosclerosis
WO2008062273A2 (en) * 2006-11-20 2008-05-29 Cadila Pharmaceuticals Limited Solid oral dosage form having antidiabetic drug combination
TWI421102B (zh) 2007-07-19 2014-01-01 Takeda Pharmaceutical 固態製劑
KR20100040937A (ko) 2007-07-26 2010-04-21 암젠 인크 변형된 레시틴-콜레스테롤 아실트랜스퍼라제 효소
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
US20130108699A1 (en) * 2010-04-26 2013-05-02 Jose Antonio Matji Tuduri Highly dispersible granulate for the preparation of formulations of high dosage active substances and procedure for obtaining high dosage active substances thereof
RU2451506C1 (ru) 2011-06-02 2012-05-27 Сергей Юрьевич Лешков Комбинация для лечения сахарного диабета и его осложнений
WO2013086443A1 (en) 2011-12-08 2013-06-13 Amgen Inc. Agonistic human lcat antigen binding proteins and their use in therapy
CA2859174C (en) * 2011-12-12 2019-03-05 Orbis Biosciences, Inc. Sustained release particle formulations
CN104127424A (zh) * 2014-07-30 2014-11-05 沈阳药科大学 格列本脲衍生物及其制备方法和应用
CN105030793A (zh) * 2015-08-25 2015-11-11 瑞阳制药有限公司 二甲双胍格列本脲胶囊及其制备方法
WO2019070109A1 (es) * 2017-10-03 2019-04-11 Infinite Clinical Research International, S.A. De C.V. Triconjugado para el tratamiento de diabetes mellitus
CN115461344B (zh) 2020-04-01 2024-01-12 杭州中美华东制药有限公司 一种glp-1受体激动剂的晶型a及其制备方法
JP2023528726A (ja) 2020-04-01 2023-07-06 ハンジョウ ジョンメイ フアドン ファーマシューティカル シーオー．，エルティーディー． Ｇｌｐ１ｒアゴニスト遊離塩基の薬学的に許容される酸塩類およびその調製法
KR102484756B1 (ko) * 2020-11-13 2023-01-06 한국생산기술연구원 용해성 증대 및 취급용이성을 갖는 파우더 배지의 과립화 방법
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

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Also Published As

Publication number Publication date
WO2000003742A2 (en) 2000-01-27
JP2003292443A (ja) 2003-10-15
KR100478347B1 (ko) 2005-03-23
CN1146427C (zh) 2004-04-21
EP1011684A2 (en) 2000-06-28
KR20040053177A (ko) 2004-06-23
EP2269613A2 (en) 2011-01-05
US6303146B1 (en) 2001-10-16
AU2003261560A1 (en) 2005-05-26
EP1435240A2 (en) 2004-07-07
DK0974356T3 (da) 2003-10-27
CA2303537A1 (en) 2000-01-27
TW200303208A (en) 2003-09-01
DZ2846A1 (fr) 2003-12-01
ID25784A (id) 2000-11-02
RU2286788C2 (ru) 2006-11-10
TW555560B (en) 2003-10-01
EP2269613A3 (en) 2012-10-17
DE69818444D1 (de) 2003-10-30
DE69818444T2 (de) 2004-05-06
PT974356E (pt) 2004-02-27
SI0974356T1 (en) 2003-12-31
NZ503248A (en) 2002-09-27
CA2303537C (en) 2005-12-06
CN1486698A (zh) 2004-04-07
ZA200001159B (en) 2001-05-31
OA11400A (en) 2004-04-08
MY129552A (en) 2007-04-30
EP0974356A1 (en) 2000-01-26
AU753604B2 (en) 2002-10-24
MA24930A1 (fr) 2000-04-01
ES2206868T3 (es) 2004-05-16
AR065970A2 (es) 2009-07-15
AU5417999A (en) 2000-02-07
USRE38629E1 (en) 2004-10-19
CN1275082A (zh) 2000-11-29
BR9906600A (pt) 2000-07-18
RU2003126257A (ru) 2005-02-27
AP1450A (en) 2005-07-25
EP1435240A3 (en) 2009-08-12
UY25611A1 (es) 2000-08-21
KR20010030603A (ko) 2001-04-16
RU2226396C2 (ru) 2004-04-10
AP2000001757A0 (en) 2000-03-31
AR013052A1 (es) 2000-11-22
WO2000003742A3 (en) 2000-04-20
JP2002520371A (ja) 2002-07-09
TWI245632B (en) 2005-12-21
EP0974356B1 (en) 2003-09-24

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