ATE212547T1 - Arzneizubereitungen enthaltend mikronisiertes nebivolol - Google Patents

Arzneizubereitungen enthaltend mikronisiertes nebivolol

Info

Publication number
ATE212547T1
ATE212547T1 AT95908927T AT95908927T ATE212547T1 AT E212547 T1 ATE212547 T1 AT E212547T1 AT 95908927 T AT95908927 T AT 95908927T AT 95908927 T AT95908927 T AT 95908927T AT E212547 T1 ATE212547 T1 AT E212547T1
Authority
AT
Austria
Prior art keywords
pct
preparations containing
medicinal preparations
containing micronized
micronized nebivolol
Prior art date
Application number
AT95908927T
Other languages
English (en)
Inventor
Eugeen Jans
Guido Franciscus Smans
Paul Marie Victor Gilis
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22731545&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE212547(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE212547T1 publication Critical patent/ATE212547T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Dental Preparations (AREA)
AT95908927T 1994-02-17 1995-02-10 Arzneizubereitungen enthaltend mikronisiertes nebivolol ATE212547T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19798894A 1994-02-17 1994-02-17
PCT/EP1995/000489 WO1995022325A1 (en) 1994-02-17 1995-02-10 Compositions containing micronized nebivolol

Publications (1)

Publication Number Publication Date
ATE212547T1 true ATE212547T1 (de) 2002-02-15

Family

ID=22731545

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95908927T ATE212547T1 (de) 1994-02-17 1995-02-10 Arzneizubereitungen enthaltend mikronisiertes nebivolol

Country Status (30)

Country Link
US (1) US5759580A (de)
EP (1) EP0744946B1 (de)
JP (1) JP3810079B2 (de)
KR (1) KR100361636B1 (de)
CN (1) CN1112921C (de)
AT (1) ATE212547T1 (de)
AU (1) AU688860B2 (de)
BR (1) BR9506828A (de)
CA (1) CA2182582C (de)
CY (1) CY2329B1 (de)
CZ (1) CZ290844B6 (de)
DE (1) DE69525241T2 (de)
DK (1) DK0744946T3 (de)
ES (1) ES2171533T3 (de)
FI (1) FI117888B (de)
HU (1) HU221848B1 (de)
IL (1) IL112659A (de)
MX (1) MX9603314A (de)
MY (1) MY115339A (de)
NO (1) NO314712B1 (de)
NZ (1) NZ279822A (de)
PL (1) PL178505B1 (de)
PT (1) PT744946E (de)
RU (1) RU2137473C1 (de)
SG (1) SG47487A1 (de)
SI (1) SI0744946T1 (de)
SK (1) SK283250B6 (de)
TW (1) TW355683B (de)
WO (1) WO1995022325A1 (de)
ZA (1) ZA951294B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT801564E (pt) * 1994-12-28 2002-09-30 Janssen Pharmaceutica Nv Utilizacao de nebivolol como agente anti-aterogernico
PT869772E (pt) 1995-12-27 2002-03-28 Janssen Pharmaceutica Nv Forma galenica solida bioadesiva
DE19637082A1 (de) * 1996-09-12 1998-03-19 Boehringer Mannheim Gmbh Schnellzerfallende Pellets
US7025991B2 (en) * 1997-06-13 2006-04-11 Nanodel Technologies Gmbh Drug targeting system, method of its preparation and its use
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
AR016827A1 (es) * 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
US20030152636A1 (en) * 2000-02-23 2003-08-14 Nanopharm Ag Method of treating cancer
US6531158B1 (en) * 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients
ATE437637T1 (de) 2001-05-02 2009-08-15 Nitromed Inc Nitrosiertes und nitrosyliertes nebivolol und seine metaboliten, zusammensetzungen und anwendungsverfahren
RU2214234C1 (ru) * 2002-11-25 2003-10-20 Нестерук Владимир Викторович ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ СВОЙСТВАМИ КАРДИОСЕЛЕКТИВНОГО β1-АДРЕНОБЛОКАТОРА
RU2286779C2 (ru) * 2003-02-06 2006-11-10 Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" Лекарственная форма, обладающая диуретическим и антигипертензивным действием, и способ ее изготовления
US7803838B2 (en) * 2004-06-04 2010-09-28 Forest Laboratories Holdings Limited Compositions comprising nebivolol
BRPI0513672A (pt) 2004-07-30 2008-05-13 Torrent Pharmaceuticals Limita processo aperfeiçoado para a preparação de 2h-1-benzopiran-2metanol, (alfa). (alfa)' [iminobis (metileno)] bis [6-fluoro-3, 4-dihidro, [2r* [r* [r* (s*)]]]], composição farmacêutica, forma t1 amorfa, e processo para a preparação da forma t1 de hidrocloreto de nebivolol
PL1776354T3 (pl) * 2004-08-11 2010-09-30 Hetero Drugs Ltd Nowy sposób wytwarzania związków pośrednich nebiwololu
US7344907B2 (en) * 2004-11-19 2008-03-18 International Business Machines Corporation Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale
WO2006083779A2 (en) * 2005-01-31 2006-08-10 Mylan Laboratories, Inc. Pharmaceutical composition comprising hydroxylated nebivolol
EP1850842A1 (de) * 2005-02-11 2007-11-07 Stada Arzneimittel Ag Pharmazeutische zusammensetzungen nebivolo und ein hydrophiles polymer
US7560575B2 (en) 2005-12-28 2009-07-14 Acino Pharma Ag Process for preparation of racemic Nebivolol
EP1803716B1 (de) * 2005-12-28 2012-07-25 Acino Pharma AG Ein Verfahren zur Herstellung von racemischem Nebivolol
WO2007083318A1 (en) * 2006-01-18 2007-07-26 Hetero Drugs Limited Process for isolation of desired isomers of nebivolol intermediates
EP1839658A1 (de) * 2006-03-30 2007-10-03 Hexal A/S Pharmazeutische Zusammensetzungen enthaltend mikronisiertes Nebivolol
DE502007003278D1 (de) * 2006-08-04 2010-05-12 Alfred E Tiefenbacher Gmbh & C Pharmazeutische Zusammensetzung enthaltend Nebivolol
DE102006036579A1 (de) * 2006-08-04 2008-02-07 Alfred E. Tiefenbacher Gmbh & Co.Kg Pharmazeutische Zusammensetzung
UA97813C2 (uk) * 2006-12-05 2012-03-26 Янссен Фармацевтика Н.В. Фумаратна сіль (альфа s, бета r)-6-бром-альфа-[2-(диметиламіно)етил]-2-метоксі-альфа-1-нафталеніл-бета-феніл-3-хінолінетанолу
WO2008089549A1 (en) * 2007-01-22 2008-07-31 Genpharm Ulc Pharmaceutical compositions comprising nebivolol or a nebivolol analogue
WO2009004649A2 (en) * 2007-05-21 2009-01-08 Sun Pharmaceutical Industries Limited Enteric coated pharmaceutical compositions
US20090030071A1 (en) * 2007-07-26 2009-01-29 Shaw Andrew A Treatment of Cardiovascular Disease in Mexican Americans Using Nebivolol
CN101463024B (zh) 2007-12-21 2011-06-08 上海现代制药股份有限公司 一种制备rrrs和sssr型的奈必洛尔中间体混合物的方法
WO2009091777A1 (en) * 2008-01-15 2009-07-23 Forest Laboratories Holdings Limited Nebivolol in the treatment of sexual dysfunction
EP2163551B1 (de) 2008-09-08 2011-11-16 Cadila Pharmaceuticals Ltd. Verbesserter Herstellungsprozess für Nebivolol-Hydrocholorid
IT1395354B1 (it) 2009-07-23 2012-09-14 Zach System Spa Processo di preparazione di nebivololo
IT1397962B1 (it) 2010-02-11 2013-02-04 Menarini Int Operations Lu Sa Processo per la preparazione del nebivololo.
KR20110130872A (ko) * 2010-05-28 2011-12-06 현대약품 주식회사 결정형 염산 네비볼롤을 포함하는 약학 조성물 및 제조방법
WO2012003181A2 (en) * 2010-07-02 2012-01-05 Fmc Corporation Solid forms
CN105085499B (zh) * 2015-08-07 2018-09-25 上海现代制药海门有限公司 盐酸奈必洛尔中间体混合物的结晶分离方法
CN110809471A (zh) 2017-04-28 2020-02-18 阿沙纳生物科学公司 治疗特应性皮炎以及提高活性药物成分稳定性的制剂、方法、试剂盒和剂型
US12576026B2 (en) * 2020-07-08 2026-03-17 Extrovis Ag Formulations of nebivolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60107106A (ja) * 1983-11-15 1985-06-12 Mitsubishi Electric Corp 曲線補間装置
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol
CA1337432C (en) * 1988-03-23 1995-10-24 Raymond M. Xhonneux Method of lowering the blood pressure
JPH02264744A (ja) * 1989-04-04 1990-10-29 Kyowa Hakko Kogyo Co Ltd 光学活性なｐ―フルオロフェノキシ誘導体およびその製造法

Also Published As

Publication number Publication date
CY2329B1 (en) 2004-02-06
IL112659A0 (en) 1995-05-26
EP0744946B1 (de) 2002-01-30
HU221848B1 (hu) 2003-02-28
HU9602272D0 (en) 1996-10-28
DE69525241T2 (de) 2002-08-29
CA2182582C (en) 2005-03-29
NZ279822A (en) 1997-04-24
US5759580A (en) 1998-06-02
MY115339A (en) 2003-05-31
ES2171533T3 (es) 2002-09-16
AU688860B2 (en) 1998-03-19
HUT75332A (en) 1997-05-28
CZ234696A3 (en) 1996-11-13
ZA951294B (en) 1996-08-16
DE69525241D1 (de) 2002-03-14
DK0744946T3 (da) 2002-05-06
CN1140991A (zh) 1997-01-22
NO314712B1 (no) 2003-05-12
SK283250B6 (sk) 2003-04-01
KR100361636B1 (ko) 2003-02-11
JP3810079B2 (ja) 2006-08-16
FI963227L (fi) 1996-08-16
RU2137473C1 (ru) 1999-09-20
NO963439L (no) 1996-08-16
PL315973A1 (en) 1996-12-23
SI0744946T1 (en) 2002-06-30
PL178505B1 (pl) 2000-05-31
FI117888B (fi) 2007-04-13
CN1112921C (zh) 2003-07-02
IL112659A (en) 1999-06-20
PT744946E (pt) 2002-07-31
SG47487A1 (en) 1998-04-17
FI963227A0 (fi) 1996-08-16
AU1706895A (en) 1995-09-04
JPH09508913A (ja) 1997-09-09
TW355683B (en) 1999-04-11
BR9506828A (pt) 1997-09-30
WO1995022325A1 (en) 1995-08-24
SK105896A3 (en) 1997-05-07
CA2182582A1 (en) 1995-08-24
MX9603314A (es) 1997-02-28
EP0744946A1 (de) 1996-12-04
CZ290844B6 (cs) 2002-10-16

Similar Documents

Publication Publication Date Title
DE69525241D1 (de) Arzneizubereitungen enthaltend mikronisiertes nebivolol
NO963053D0 (no) Kosmetiske eller farmasöytiske preparater inneholdende mangiferin eller derivater derav
ATE206123T1 (de) Phenylxanthin-derivate
IL108520A0 (en) Imidazopyridine derivatives, processes for the preparation thereof, and pharmaceutical compositions containing them
IL111861A (en) Phenyl-n-substituted azabicycloalkene derivatives and pharmaceutical compositions containing them
NO972623D0 (no) Framasöytisk blanding omfattende lamotrigin
NO962285D0 (no) N-substituerte azabicykloheptan-derivater anvendt for eksempel som neuroleptika
GEP20032970B (en) Pharmaceutical Compositions of Tizoxanide and Nitazoxanide
IL114719A0 (en) N-substituted azabicycloheptane derivatives their preparation and use thereof
NO950177L (no) Farmakologisk aktive erivater
ZA9429B (en) Pyrrolidine derivatives their preparation and medicaments containing them

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification