IT1395354B1 - Processo di preparazione di nebivololo - Google Patents
Processo di preparazione di nebivololoInfo
- Publication number
- IT1395354B1 IT1395354B1 ITMI2009A001309A ITMI20091309A IT1395354B1 IT 1395354 B1 IT1395354 B1 IT 1395354B1 IT MI2009A001309 A ITMI2009A001309 A IT MI2009A001309A IT MI20091309 A ITMI20091309 A IT MI20091309A IT 1395354 B1 IT1395354 B1 IT 1395354B1
- Authority
- IT
- Italy
- Prior art keywords
- preparation process
- nebivolol
- nebivolol preparation
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2009A001309A IT1395354B1 (it) | 2009-07-23 | 2009-07-23 | Processo di preparazione di nebivololo |
| AU2010275690A AU2010275690B2 (en) | 2009-07-23 | 2010-07-23 | Process for preparing Nebivolol |
| CA2763952A CA2763952C (en) | 2009-07-23 | 2010-07-23 | Process for preparing nebivolol |
| CN201080029171.7A CN102471325B (zh) | 2009-07-23 | 2010-07-23 | 制备奈必洛尔的方法 |
| JP2012520961A JP5744864B2 (ja) | 2009-07-23 | 2010-07-23 | ネビボロールの製造方法 |
| PCT/EP2010/004532 WO2011009628A1 (en) | 2009-07-23 | 2010-07-23 | Process for preparing nebivolol |
| PL10754262T PL2456768T3 (pl) | 2009-07-23 | 2010-07-23 | Sposób otrzymywania nebiwololu |
| US13/383,108 US8969597B2 (en) | 2009-07-23 | 2010-07-23 | Process for preparing nebivolol |
| ES10754262.3T ES2529217T3 (es) | 2009-07-23 | 2010-07-23 | Proceso para preparar nebivolol |
| BR112012001503A BR112012001503B1 (pt) | 2009-07-23 | 2010-07-23 | processo de separação, processo para preparação de nebivolol e composto |
| EP10754262.3A EP2456768B1 (en) | 2009-07-23 | 2010-07-23 | Process for preparing nebivolol |
| IL216695A IL216695A (en) | 2009-07-23 | 2011-11-30 | Process for making nebibolol |
| HRP20141187AT HRP20141187T1 (hr) | 2009-07-23 | 2014-12-08 | Postupak pripreme nebivolola |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2009A001309A IT1395354B1 (it) | 2009-07-23 | 2009-07-23 | Processo di preparazione di nebivololo |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITMI20091309A1 ITMI20091309A1 (it) | 2011-01-24 |
| IT1395354B1 true IT1395354B1 (it) | 2012-09-14 |
Family
ID=41650106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI2009A001309A IT1395354B1 (it) | 2009-07-23 | 2009-07-23 | Processo di preparazione di nebivololo |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8969597B2 (it) |
| EP (1) | EP2456768B1 (it) |
| JP (1) | JP5744864B2 (it) |
| CN (1) | CN102471325B (it) |
| AU (1) | AU2010275690B2 (it) |
| BR (1) | BR112012001503B1 (it) |
| CA (1) | CA2763952C (it) |
| ES (1) | ES2529217T3 (it) |
| HR (1) | HRP20141187T1 (it) |
| IL (1) | IL216695A (it) |
| IT (1) | IT1395354B1 (it) |
| PL (1) | PL2456768T3 (it) |
| WO (1) | WO2011009628A1 (it) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016185492A1 (en) * | 2015-05-19 | 2016-11-24 | Ipca Laboratories Limited | Process for preparation of nebivolol and it's salts |
| CN105085499B (zh) * | 2015-08-07 | 2018-09-25 | 上海现代制药海门有限公司 | 盐酸奈必洛尔中间体混合物的结晶分离方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1337429C (en) * | 1983-12-05 | 1995-10-24 | Guy Rosalia Eugene Van Lommen | Derivatives of 2,2'-iminobisethanol |
| US4654362A (en) * | 1983-12-05 | 1987-03-31 | Janssen Pharmaceutica, N.V. | Derivatives of 2,2'-iminobisethanol |
| CA1337432C (en) | 1988-03-23 | 1995-10-24 | Raymond M. Xhonneux | Method of lowering the blood pressure |
| TW355683B (en) | 1994-02-17 | 1999-04-11 | Janssen Pharmaceutica Nv | Composition containing micronized nebivolol |
| WO1996034842A1 (en) * | 1995-05-05 | 1996-11-07 | Hoechst Celanese Corporation | Separation of alpha-arylpropionic acid ester diastereomers by distillation |
| MX2007000911A (es) | 2004-07-30 | 2007-04-12 | Torrent Pharmaceuticals Ltd | Nevibolol y sus sales farmaceuticamente aceptables, proceso para su preparacion y composiciones farmaceuticas de nevibolol. |
| ES2341250T3 (es) | 2004-08-11 | 2010-06-17 | Hetero Drugs Limited | Procedimiento novedoso de preparacion de intermediarios de nebivolol. |
| AT502220A1 (de) * | 2005-07-19 | 2007-02-15 | Pharmacon Forschung & Beratung | Verfahren zur herstellung von nebivolol |
| EP1803716B1 (en) | 2005-12-28 | 2012-07-25 | Acino Pharma AG | A process for preparation of racemic nebivolol |
| US7560575B2 (en) | 2005-12-28 | 2009-07-14 | Acino Pharma Ag | Process for preparation of racemic Nebivolol |
| ITMI20061889A1 (it) | 2006-10-03 | 2008-04-04 | Zambon Spa | Processo di preparazione di nebivololo |
| PL2228374T3 (pl) * | 2006-11-27 | 2013-11-29 | Zach System Spa | Mrówczan nebiwololu |
| PT2102196E (pt) * | 2006-11-27 | 2012-10-31 | Zach System Spa | Processo para a preparação de nebivolol |
| ITMI20080547A1 (it) * | 2008-03-31 | 2009-10-01 | Zach System Spa | Processo di preparazione di nebivololo |
-
2009
- 2009-07-23 IT ITMI2009A001309A patent/IT1395354B1/it active
-
2010
- 2010-07-23 PL PL10754262T patent/PL2456768T3/pl unknown
- 2010-07-23 WO PCT/EP2010/004532 patent/WO2011009628A1/en active Application Filing
- 2010-07-23 EP EP10754262.3A patent/EP2456768B1/en active Active
- 2010-07-23 CA CA2763952A patent/CA2763952C/en active Active
- 2010-07-23 ES ES10754262.3T patent/ES2529217T3/es active Active
- 2010-07-23 AU AU2010275690A patent/AU2010275690B2/en active Active
- 2010-07-23 JP JP2012520961A patent/JP5744864B2/ja active Active
- 2010-07-23 US US13/383,108 patent/US8969597B2/en active Active
- 2010-07-23 BR BR112012001503A patent/BR112012001503B1/pt active IP Right Grant
- 2010-07-23 CN CN201080029171.7A patent/CN102471325B/zh active Active
-
2011
- 2011-11-30 IL IL216695A patent/IL216695A/en active IP Right Grant
-
2014
- 2014-12-08 HR HRP20141187AT patent/HRP20141187T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20141187T1 (hr) | 2015-01-30 |
| AU2010275690B2 (en) | 2016-07-21 |
| JP2012533588A (ja) | 2012-12-27 |
| BR112012001503A2 (pt) | 2015-09-01 |
| EP2456768B1 (en) | 2014-11-19 |
| BR112012001503B1 (pt) | 2020-05-19 |
| ITMI20091309A1 (it) | 2011-01-24 |
| CA2763952C (en) | 2017-06-20 |
| JP5744864B2 (ja) | 2015-07-08 |
| CA2763952A1 (en) | 2011-01-27 |
| CN102471325A (zh) | 2012-05-23 |
| CN102471325B (zh) | 2015-09-09 |
| AU2010275690A1 (en) | 2011-12-22 |
| WO2011009628A1 (en) | 2011-01-27 |
| IL216695A (en) | 2014-04-30 |
| IL216695A0 (en) | 2012-02-29 |
| US8969597B2 (en) | 2015-03-03 |
| PL2456768T3 (pl) | 2015-04-30 |
| ES2529217T3 (es) | 2015-02-18 |
| US20120108826A1 (en) | 2012-05-03 |
| EP2456768A1 (en) | 2012-05-30 |
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