BRPI0919868A2 - processo - Google Patents

processo

Info

Publication number
BRPI0919868A2
BRPI0919868A2 BRPI0919868A BRPI0919868A BRPI0919868A2 BR PI0919868 A2 BRPI0919868 A2 BR PI0919868A2 BR PI0919868 A BRPI0919868 A BR PI0919868A BR PI0919868 A BRPI0919868 A BR PI0919868A BR PI0919868 A2 BRPI0919868 A2 BR PI0919868A2
Authority
BR
Brazil
Application number
BRPI0919868A
Other languages
English (en)
Inventor
Grazynia Stochel
Krystyna Urbanska
Luís Guilherme Da Silva Arnaut Moreira
Maria Miguéns Pereira
Sebastião José Formosinho Sanches Simões
Sérgio Paulo Magalhães Simões
Original Assignee
Bluepharma Ind Farmacêutica S A
Univ De Coimbra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bluepharma Ind Farmacêutica S A, Univ De Coimbra filed Critical Bluepharma Ind Farmacêutica S A
Publication of BRPI0919868A2 publication Critical patent/BRPI0919868A2/pt
Publication of BRPI0919868B1 publication Critical patent/BRPI0919868B1/pt
Publication of BRPI0919868B8 publication Critical patent/BRPI0919868B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
BRPI0919868A 2008-10-24 2009-10-22 processo para a preparação de um derivado de clorina ou de bacterioclorina BRPI0919868B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0819594.3A GB0819594D0 (en) 2008-10-24 2008-10-24 Process
GB0819594.3 2008-10-24
PCT/PT2009/000057 WO2010047611A1 (en) 2008-10-24 2009-10-22 Process for preparing chlorins and their pharmaceutical uses

Publications (3)

Publication Number Publication Date
BRPI0919868A2 true BRPI0919868A2 (pt) 2015-12-15
BRPI0919868B1 BRPI0919868B1 (pt) 2020-10-27
BRPI0919868B8 BRPI0919868B8 (pt) 2021-05-25

Family

ID=40133817

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919868A BRPI0919868B8 (pt) 2008-10-24 2009-10-22 processo para a preparação de um derivado de clorina ou de bacterioclorina

Country Status (16)

Country Link
US (1) US9670217B2 (pt)
EP (1) EP2346874B1 (pt)
JP (1) JP5567024B2 (pt)
CN (1) CN102227432B (pt)
AU (1) AU2009307106B2 (pt)
BR (1) BRPI0919868B8 (pt)
CA (1) CA2741429C (pt)
DK (1) DK2346874T3 (pt)
ES (1) ES2450136T3 (pt)
GB (1) GB0819594D0 (pt)
HK (1) HK1160848A1 (pt)
PL (1) PL2346874T3 (pt)
PT (1) PT2346874E (pt)
RU (1) RU2513483C2 (pt)
WO (1) WO2010047611A1 (pt)
ZA (1) ZA201102760B (pt)

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US8524239B2 (en) 2010-07-09 2013-09-03 The United States of America as represented by the Secrectary, Department of Health and Human Services Photosensitizing antibody-fluorophore conjugates
WO2013009475A1 (en) * 2011-07-11 2013-01-17 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Photosensitizing antibody-phuorophore conjugates
US9371555B2 (en) 2012-06-01 2016-06-21 Concordia Laboratories Inc. Lighting systems and methods of using lighting systems for in vitro potency assay for photofrin
CN103721257B (zh) * 2012-10-16 2016-12-21 无锡兆真辐射技术有限公司 光敏素催化分解过氧化氢系列药物
GB201221125D0 (en) 2012-11-23 2013-01-09 Morex Dev Partners Llp Pharmaceutial formulations
WO2014110149A2 (en) * 2013-01-08 2014-07-17 Stoneburner Jon F Method of testing or treating the presence of live viruses
JP6796058B2 (ja) 2014-08-08 2020-12-02 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ インビトロおよびインビボにおける標的の光制御除去
RU2712266C9 (ru) * 2015-03-20 2020-03-11 Лузитин, С.А. Атропоизомеры галогенированных тетрафенилбактериохлоринов и хлоринов и их применение в фотодинамической терапии
EP3331909A1 (en) 2015-08-07 2018-06-13 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Near infrared photoimmunotherapy (nir-pit) of suppressor cells to treat cancer
SG10202011033QA (en) 2015-08-18 2020-12-30 Rakuten Medical Inc Phthalocyanine dye conjugates and their storage
EP3337514B8 (en) 2015-08-18 2022-04-06 Rakuten Medical, Inc. Composition comprising a conjugate comprising a phthalocyanine dye linked to a targeting molecule for photoimmunotherapy
WO2017051435A1 (en) * 2015-09-22 2017-03-30 Council Of Scientific And Industrial Research Chlorin based compounds, a process for preparation thereof and use as photodynamic therapeutic agents and fluorescent probes
US10744212B2 (en) 2016-03-14 2020-08-18 General Electric Company Topical application of nerve labeling dyes for image-guided surgery
WO2018065384A1 (en) * 2016-10-03 2018-04-12 Galderma Research & Development Expression profiles of abc and slc transporters in human and minipig skin, liver and kidney
JP7223218B2 (ja) * 2017-05-22 2023-02-16 国立大学法人京都大学 テトラフェニルポルフィリン誘導体
US11344574B2 (en) * 2017-09-29 2022-05-31 Duke University Fluoro substituted porphyrin compounds, pharmaceutical compositions comprising the same, and methods of preparing and using the same
CN109912607B (zh) * 2018-12-11 2021-01-22 南华大学 一类卟啉-白杨素复合物及其抗肿瘤活性
CN109651383B (zh) * 2019-01-25 2021-11-16 华东理工大学 用于光敏剂的化合物及其应用
CN114222803A (zh) * 2019-05-20 2022-03-22 尼尔瓦纳科学股份有限公司 窄发射染料、包含其的组合物以及制备和使用其的方法
RU2725876C1 (ru) * 2019-07-15 2020-07-07 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) Производные фторсодержащих хлоринов, проявляющие противоопухолевую активность
WO2022100750A1 (zh) * 2020-11-16 2022-05-19 北京厚燊维康科技有限责任公司 可用于光动力治疗或诊断的制剂
RU2759743C2 (ru) * 2021-04-14 2021-11-17 Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр радиологии» Министерства здравоохранения Российской Федерации (ФГБУ «НМИЦ радиологии» Минздрава России) Способ комбинированного лечения локализованного t1-t2n0m0 рака гортани
CN117460790A (zh) * 2021-08-18 2024-01-26 富士胶片株式会社 荧光性化合物及使用了该荧光性化合物的荧光标记生物物质
WO2023059180A1 (en) * 2021-10-06 2023-04-13 Tunku Abdul Rahman University Of Management And Technology (Tar Umt) Treating skin diseases using a photodynamic therapy (pdt) and a topical agent photosensitizer formulation
CN114813592A (zh) * 2022-03-11 2022-07-29 华南理工大学 一种探究羟基氯喹在自然水体中降解机理的方法
CN114870011B (zh) * 2022-03-24 2023-06-06 深圳大学 一种增强实体瘤内原卟啉ix蓄积的微针贴片及其制备方法

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US4562075A (en) 1982-05-20 1985-12-31 Nelson Research & Development Co. Penetration enhancers for transdermal drug delivery of systemic agents
US4405616A (en) 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US3989816A (en) 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4218803A (en) 1979-05-25 1980-08-26 Clifford Jack R Implement for cleaning tubular culverts
US5171741A (en) 1989-04-21 1992-12-15 Health Research, Inc. Bacteriochlorophyll-a derivatives useful in photodynamic therapy
US5079262A (en) 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
JPH08506566A (ja) 1992-06-19 1996-07-16 ザ・ユニバーシティ・オブ・トリド ポルフィリン系イミンの製造方法及び使用方法
US5591847A (en) 1994-05-23 1997-01-07 Health Research, Inc. Long wavelength absorbing photosensitizers related to purpurin-18, bacteriopurpurin-18 and related compounds with imide linkages
RU2071320C1 (ru) * 1994-09-29 1997-01-10 Акционерное общество закрытого типа Научно-производственное предприятие "Мелодит" Сенсибилизатор для фотодинамического разрушения клеток злокачественных новообразований
US5648485A (en) 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US5770730A (en) 1996-03-08 1998-06-23 Health Research, Inc. Synthesis of carbodimide analogs of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer
JP2000007693A (ja) * 1998-06-26 2000-01-11 Lederle Japan Ltd クロリン誘導体
DE69934328T2 (de) 1998-12-09 2007-07-19 Yeda Research And Development Co., Ltd. Palladiumsubstituierte bakteriochlorophyllderivate und deren verwendung
US6376483B1 (en) 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production
US6624187B1 (en) 2000-06-12 2003-09-23 Health Research, Inc. Long wave length absorbing bacteriochlorin alkyl ether analogs
GB0121023D0 (en) * 2001-08-30 2001-10-24 Norwegian Radium Hospital Res Compound
PT102721B (pt) * 2002-02-01 2011-01-24 Cipan Companhia Industr Prod De Antibioticos S A Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação
EP1517684B1 (en) 2002-06-27 2009-07-22 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
FR2877943B1 (fr) * 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
WO2006089122A2 (en) 2005-02-18 2006-08-24 North Carolina State University De novo synthesis of bacteriochlorins
US20090318370A1 (en) 2007-02-19 2009-12-24 Rei Medical Co., Ltd. Novel glycoconjugated chlorin derivatives and method of producing the same

Also Published As

Publication number Publication date
RU2513483C2 (ru) 2014-04-20
JP5567024B2 (ja) 2014-08-06
CA2741429A1 (en) 2011-04-29
JP2012506425A (ja) 2012-03-15
CA2741429C (en) 2017-04-18
WO2010047611A1 (en) 2010-04-29
EP2346874A1 (en) 2011-07-27
US20110250143A1 (en) 2011-10-13
US9670217B2 (en) 2017-06-06
DK2346874T3 (en) 2014-03-03
BRPI0919868B8 (pt) 2021-05-25
PL2346874T3 (pl) 2014-05-30
ZA201102760B (en) 2012-07-25
RU2011114878A (ru) 2012-11-27
GB0819594D0 (en) 2008-12-03
CN102227432A (zh) 2011-10-26
CN102227432B (zh) 2015-04-22
WO2010047611A9 (en) 2010-07-22
PT2346874E (pt) 2014-03-06
AU2009307106B2 (en) 2015-05-07
ES2450136T3 (es) 2014-03-24
EP2346874B1 (en) 2013-12-04
AU2009307106A1 (en) 2010-04-29
BRPI0919868B1 (pt) 2020-10-27
HK1160848A1 (en) 2012-08-17

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/10/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/10/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 14A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2745 DE 15-08-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.