TW355683B - Composition containing micronized nebivolol - Google Patents

Composition containing micronized nebivolol

Info

Publication number
TW355683B
TW355683B TW084100357A TW84100357A TW355683B TW 355683 B TW355683 B TW 355683B TW 084100357 A TW084100357 A TW 084100357A TW 84100357 A TW84100357 A TW 84100357A TW 355683 B TW355683 B TW 355683B
Authority
TW
Taiwan
Prior art keywords
composition containing
containing micronized
nebivolol
micronized nebivolol
composition
Prior art date
Application number
TW084100357A
Other languages
English (en)
Inventor
Eugeen Jans
Guido Franciscus Smans
Paul Marie Victor Gilis
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22731545&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW355683(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of TW355683B publication Critical patent/TW355683B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Dental Preparations (AREA)
TW084100357A 1994-02-17 1995-01-17 Composition containing micronized nebivolol TW355683B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19798894A 1994-02-17 1994-02-17

Publications (1)

Publication Number Publication Date
TW355683B true TW355683B (en) 1999-04-11

Family

ID=22731545

Family Applications (1)

Application Number Title Priority Date Filing Date
TW084100357A TW355683B (en) 1994-02-17 1995-01-17 Composition containing micronized nebivolol

Country Status (30)

Country Link
US (1) US5759580A (zh)
EP (1) EP0744946B1 (zh)
JP (1) JP3810079B2 (zh)
KR (1) KR100361636B1 (zh)
CN (1) CN1112921C (zh)
AT (1) ATE212547T1 (zh)
AU (1) AU688860B2 (zh)
BR (1) BR9506828A (zh)
CA (1) CA2182582C (zh)
CY (1) CY2329B1 (zh)
CZ (1) CZ290844B6 (zh)
DE (1) DE69525241T2 (zh)
DK (1) DK0744946T3 (zh)
ES (1) ES2171533T3 (zh)
FI (1) FI117888B (zh)
HU (1) HU221848B1 (zh)
IL (1) IL112659A (zh)
MX (1) MX9603314A (zh)
MY (1) MY115339A (zh)
NO (1) NO314712B1 (zh)
NZ (1) NZ279822A (zh)
PL (1) PL178505B1 (zh)
PT (1) PT744946E (zh)
RU (1) RU2137473C1 (zh)
SG (1) SG47487A1 (zh)
SI (1) SI0744946T1 (zh)
SK (1) SK283250B6 (zh)
TW (1) TW355683B (zh)
WO (1) WO1995022325A1 (zh)
ZA (1) ZA951294B (zh)

Families Citing this family (35)

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Publication number Priority date Publication date Assignee Title
CN1167418C (zh) * 1994-12-28 2004-09-22 詹森药业有限公司 奈必洛尔作为抗动脉粥样化剂的用途
CZ298690B6 (cs) 1995-12-27 2007-12-27 Tibotec Pharmaceuticals Ltd. Bioadhezivní farmaceutická kompozice, dávková forma a suchý zpusob prípravy tablet
DE19637082A1 (de) 1996-09-12 1998-03-19 Boehringer Mannheim Gmbh Schnellzerfallende Pellets
WO1998056361A1 (en) * 1997-06-13 1998-12-17 Medinova Medical Consulting Gmbh Drug targeting system, method of its preparation and its use
AR016827A1 (es) 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
AR017512A1 (es) 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
US20030152636A1 (en) * 2000-02-23 2003-08-14 Nanopharm Ag Method of treating cancer
US6531158B1 (en) * 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients
CA2446064A1 (en) 2001-05-02 2002-11-07 Nitromed, Inc. Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use
US7803838B2 (en) * 2004-06-04 2010-09-28 Forest Laboratories Holdings Limited Compositions comprising nebivolol
RU2378272C2 (ru) 2004-07-30 2010-01-10 Торрент Фармасьютикалз Лимитед Небиволол и его фармацевтически приемлемые соли, способ их получения и фармацевтические композиции небиволола
ES2341250T3 (es) * 2004-08-11 2010-06-17 Hetero Drugs Limited Procedimiento novedoso de preparacion de intermediarios de nebivolol.
US7344907B2 (en) * 2004-11-19 2008-03-18 International Business Machines Corporation Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale
EP1848424B1 (en) * 2005-01-31 2017-04-05 Mylan Laboratories, Inc Pharmaceutical composition comprising hydroxylated nebivolol
WO2006084684A1 (de) * 2005-02-11 2006-08-17 Stada Arzneimittel Ag Pharmazeutische zusammensetzungen nebivolo und ein hydrophiles polymer
EP1803716B1 (en) * 2005-12-28 2012-07-25 Acino Pharma AG A process for preparation of racemic nebivolol
US7560575B2 (en) * 2005-12-28 2009-07-14 Acino Pharma Ag Process for preparation of racemic Nebivolol
US7858812B2 (en) * 2006-01-18 2010-12-28 Hetero Drugs Limited Process for isolation of desired isomers of nebivolol intermediates
EP1839658A1 (en) * 2006-03-30 2007-10-03 Hexal A/S Pharmaceutical composition comprising micronized nebivolol
DE102006036579A1 (de) * 2006-08-04 2008-02-07 Alfred E. Tiefenbacher Gmbh & Co.Kg Pharmazeutische Zusammensetzung
EP1886674B1 (de) * 2006-08-04 2010-03-31 Alfred, E. Tiefenbacher Gmbh & Co. Kg Pharmazeutische Zusammensetzung enthaltend Nebivolol
UA97813C2 (uk) * 2006-12-05 2012-03-26 Янссен Фармацевтика Н.В. Фумаратна сіль (альфа s, бета r)-6-бром-альфа-[2-(диметиламіно)етил]-2-метоксі-альфа-1-нафталеніл-бета-феніл-3-хінолінетанолу
JP5448844B2 (ja) 2007-01-22 2014-03-19 ミラン ファーマシューティカルズ ユーエルシー ネビボロールを含む固体の医薬組成物
US20100172972A1 (en) * 2007-05-21 2010-07-08 Sun Pharmaceutical Industries Limited Enteric coated pharmaceutical compositions
CA2637979A1 (en) * 2007-07-26 2009-01-26 Mylan Laboratories, Inc. Treatment of cardiovascular disease in mexican americans using nebivolol
CN101463024B (zh) 2007-12-21 2011-06-08 上海现代制药股份有限公司 一种制备rrrs和sssr型的奈必洛尔中间体混合物的方法
WO2009091777A1 (en) * 2008-01-15 2009-07-23 Forest Laboratories Holdings Limited Nebivolol in the treatment of sexual dysfunction
EP2163551B1 (en) 2008-09-08 2011-11-16 Cadila Pharmaceuticals Ltd. An improved process for the preparation of nebivolol hydrochloride
IT1395354B1 (it) 2009-07-23 2012-09-14 Zach System Spa Processo di preparazione di nebivololo
IT1397962B1 (it) 2010-02-11 2013-02-04 Menarini Int Operations Lu Sa Processo per la preparazione del nebivololo.
KR20110130872A (ko) * 2010-05-28 2011-12-06 현대약품 주식회사 결정형 염산 네비볼롤을 포함하는 약학 조성물 및 제조방법
CN102985077A (zh) * 2010-07-02 2013-03-20 Fmc有限公司 固体形式
CN105085499B (zh) * 2015-08-07 2018-09-25 上海现代制药海门有限公司 盐酸奈必洛尔中间体混合物的结晶分离方法
CN117503775A (zh) * 2017-04-28 2024-02-06 自由生物有限公司 治疗特应性皮炎以及提高活性药物成分稳定性的制剂、方法、试剂盒和剂型
US20220016025A1 (en) * 2020-07-08 2022-01-20 Vinayak Dinesh DENDUKURI Formulations of nebivolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60107106A (ja) * 1983-11-15 1985-06-12 Mitsubishi Electric Corp 曲線補間装置
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol
CA1337432C (en) * 1988-03-23 1995-10-24 Raymond M. Xhonneux Method of lowering the blood pressure
JPH02264744A (ja) * 1989-04-04 1990-10-29 Kyowa Hakko Kogyo Co Ltd 光学活性なｐ―フルオロフェノキシ誘導体およびその製造法

Also Published As

Publication number Publication date
AU688860B2 (en) 1998-03-19
DK0744946T3 (da) 2002-05-06
NZ279822A (en) 1997-04-24
SG47487A1 (en) 1998-04-17
SI0744946T1 (en) 2002-06-30
JPH09508913A (ja) 1997-09-09
NO963439L (no) 1996-08-16
CZ234696A3 (en) 1996-11-13
IL112659A (en) 1999-06-20
ES2171533T3 (es) 2002-09-16
DE69525241T2 (de) 2002-08-29
DE69525241D1 (de) 2002-03-14
PL315973A1 (en) 1996-12-23
EP0744946B1 (en) 2002-01-30
AU1706895A (en) 1995-09-04
PL178505B1 (pl) 2000-05-31
SK283250B6 (sk) 2003-04-01
EP0744946A1 (en) 1996-12-04
IL112659A0 (en) 1995-05-26
MY115339A (en) 2003-05-31
PT744946E (pt) 2002-07-31
ATE212547T1 (de) 2002-02-15
WO1995022325A1 (en) 1995-08-24
CY2329B1 (en) 2004-02-06
FI963227A0 (fi) 1996-08-16
US5759580A (en) 1998-06-02
CZ290844B6 (cs) 2002-10-16
CN1112921C (zh) 2003-07-02
CA2182582A1 (en) 1995-08-24
HU221848B1 (hu) 2003-02-28
NO314712B1 (no) 2003-05-12
BR9506828A (pt) 1997-09-30
FI963227A (fi) 1996-08-16
ZA951294B (en) 1996-08-16
JP3810079B2 (ja) 2006-08-16
CN1140991A (zh) 1997-01-22
HUT75332A (en) 1997-05-28
CA2182582C (en) 2005-03-29
RU2137473C1 (ru) 1999-09-20
SK105896A3 (en) 1997-05-07
FI117888B (fi) 2007-04-13
MX9603314A (es) 1997-02-28
HU9602272D0 (en) 1996-10-28
KR100361636B1 (ko) 2003-02-11

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