ATE204756T1 - Phosphatbindende polymere für orale verabreichung - Google Patents

Phosphatbindende polymere für orale verabreichung

Info

Publication number
ATE204756T1
ATE204756T1 AT94925819T AT94925819T ATE204756T1 AT E204756 T1 ATE204756 T1 AT E204756T1 AT 94925819 T AT94925819 T AT 94925819T AT 94925819 T AT94925819 T AT 94925819T AT E204756 T1 ATE204756 T1 AT E204756T1
Authority
AT
Austria
Prior art keywords
oral administration
binding polymers
phosphate binding
polymers
phosphate
Prior art date
Application number
AT94925819T
Other languages
English (en)
Inventor
Stephen Randall Holmes-Farley
W Harry Mandeville Iii
George Mcclelland Whitesides
Original Assignee
Geltex Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26802726&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE204756(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geltex Pharma Inc filed Critical Geltex Pharma Inc
Application granted granted Critical
Publication of ATE204756T1 publication Critical patent/ATE204756T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/795Polymers containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyurethanes Or Polyureas (AREA)
AT94925819T 1993-08-11 1994-08-10 Phosphatbindende polymere für orale verabreichung ATE204756T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10559193A 1993-08-11 1993-08-11
US08/238,458 US5496545A (en) 1993-08-11 1994-05-05 Phosphate-binding polymers for oral administration
PCT/US1994/009060 WO1995005184A2 (en) 1993-08-11 1994-08-10 Phosphate-binding polymers for oral administration

Publications (1)

Publication Number Publication Date
ATE204756T1 true ATE204756T1 (de) 2001-09-15

Family

ID=26802726

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94925819T ATE204756T1 (de) 1993-08-11 1994-08-10 Phosphatbindende polymere für orale verabreichung
AT01200604T ATE324900T1 (de) 1993-08-11 1994-08-10 Polymer zur therapeutischen anwendung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT01200604T ATE324900T1 (de) 1993-08-11 1994-08-10 Polymer zur therapeutischen anwendung

Country Status (16)

Country Link
US (1) US5496545A (de)
EP (3) EP1676581A3 (de)
JP (2) JP3113283B2 (de)
KR (1) KR100346766B1 (de)
AT (2) ATE204756T1 (de)
AU (1) AU689797B2 (de)
CA (3) CA2169356C (de)
DE (5) DE10299003I2 (de)
DK (2) DK0716606T3 (de)
ES (2) ES2260154T3 (de)
HK (2) HK1009243A1 (de)
LU (2) LU90884I2 (de)
NL (2) NL300080I1 (de)
NZ (1) NZ271826A (de)
PT (2) PT716606E (de)
WO (1) WO1995005184A2 (de)

Families Citing this family (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0684958B1 (de) * 1993-02-17 1998-06-10 Btg International Limited 1 guanidino gruppen enthaltende polymere zur verwendung in der therapie
US5487888A (en) * 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5667775A (en) * 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
GB9503061D0 (en) * 1995-02-16 1995-04-05 British Tech Group Polymeric compounds
DE19528524C2 (de) * 1995-08-03 1999-11-11 Hans Dietl Calciumhaltiges Mittel zur intestinalen Phosphatbindung und Verfahren zu seiner Herstellung
TW528597B (en) * 1996-03-05 2003-04-21 Mitsubishi Electric Corp Medicament for preventive and/or therapeutic treatment of hyperphosphatemia
CN1230118A (zh) * 1996-07-19 1999-09-29 日研化学株式会社 高磷血症治疗剂
EP0934352B1 (de) * 1996-10-23 2007-05-02 Dow Global Technologies Inc. Wasserlösliche polymere für die verminderung der absorption von diätetikem phosphat oder oxalat
AU2446497A (en) * 1997-03-25 1998-10-20 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers combined with a calcium supplement for oral administration
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6566407B2 (en) 1997-11-05 2003-05-20 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
WO1999040990A1 (en) * 1998-02-17 1999-08-19 University Of Maryland Anion binding polymers and the use thereof
WO1999047587A1 (en) * 1998-03-19 1999-09-23 Geltex Pharmaceuticals, Inc. Continuous crosslinking of polymer gels
US6294163B1 (en) 1998-10-02 2001-09-25 Geltex Pharmaceuticals, Inc. Polymers containing guanidinium groups as bile acid sequestrants
JP4749649B2 (ja) * 1998-10-12 2011-08-17 中外製薬株式会社 リン酸結合性ポリマー
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US6271264B1 (en) 1998-12-01 2001-08-07 Geltex Pharmaceuticals, Inc. Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants
MXPA01010454A (es) * 1999-04-16 2002-05-06 Abbott Lab Proceso para producir hidrocloruro de polialilamina degradada.
US6190649B1 (en) 1999-04-23 2001-02-20 Geltex Pharmaceuticals, Inc. Polyether-based bile acid sequestrants
US6362266B1 (en) 1999-09-03 2002-03-26 The Dow Chemical Company Process for reducing cohesiveness of polyallylamine polymer gels during drying
US6180754B1 (en) 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
AU7856200A (en) * 1999-10-07 2001-05-10 University Of Maryland Sugar binding polymers and the use thereof
DE60024479T2 (de) * 1999-10-15 2006-05-18 Dow Global Technologies, Inc., Midland Dialyselösung die polyglycol als osmotischen mittels enthält
US20030202958A1 (en) * 1999-10-15 2003-10-30 Strickland Alan D. Dialysis solution including polyglycol osmotic agent
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US6733780B1 (en) * 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
ATE286386T1 (de) * 1999-10-19 2005-01-15 Genzyme Corp Direktkomprimierter tablettenkern auf polymerbasis
US20040059065A1 (en) * 2000-03-09 2004-03-25 Takeshi Goto Crosslinked anion-exchange resin or salt thereof
WO2001066607A1 (fr) * 2000-03-09 2001-09-13 Hisamitsu Pharmaceutical Co., Inc. Resine echangeuse d'anions reticulee ou sel de celle-ci et adsorbant phosphoreux la contenant
WO2001068106A1 (fr) 2000-03-13 2001-09-20 Hisamitsu Pharmaceutical Co., Inc. Prophylactiques et/ou remedes pour hyperphosphatemie
WO2002032974A2 (en) * 2000-10-18 2002-04-25 Fujisawa Pharmaceutical Co., Ltd. Polymer and its use for the treatment and/or prevention of hyperphosphoremia
AU2002224109A1 (en) * 2000-11-28 2002-06-11 Mitsubishi Pharma Corporation Excretion accelerator for accumulative chlorine compound
CA2430122C (en) * 2000-11-28 2010-08-24 Mitsubishi Pharma Corporation Antiobesity agent and health food
AT409630B (de) * 2000-12-13 2002-09-25 Dsm Fine Chem Austria Gmbh Alkylierung von n-bzw. amino- oder ammoniumgruppen haltigen, vernetzten polymeren
DE10065710A1 (de) * 2000-12-29 2002-07-04 Bayer Ag Arzneimittel enthaltend ein Polyamin als Wirksubstanz
WO2002066543A1 (en) * 2001-02-16 2002-08-29 Genzyme Corporation Method of drying a material having a cohesive phase
AU2002257145B2 (en) * 2001-04-18 2005-06-02 Genzyme Corporation Method for lowering serum glucose
KR20040018357A (ko) * 2001-04-18 2004-03-03 젠자임 코포레이션 저염 형태의 폴리알릴아민
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
BR0209124A (pt) 2001-04-18 2005-02-09 Genzyme Corp Método para tratar uma sìndrome x ou inibir o inìcio dos sintomas da sìndrome x e uso de uma quantidade terapeuticamente efetiva de um sal de pelo menos um polìmero de amina alifática
EP1923064B1 (de) 2001-04-18 2017-06-28 Genzyme Corporation Verwendung von Aminpolymeren zur Minderung des Serumglukosegehaltes
MX2008011686A (es) * 2001-05-25 2010-05-27 Marathon Oil Co Inhibicion de sulfuracion del deposito utilizando una inyeccion de agua tratada.
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
JP2003033651A (ja) * 2001-07-24 2003-02-04 Chisso Corp 経口リン吸着剤及びそれを含む食品
CN1270724C (zh) 2001-07-30 2006-08-23 三菱制药株式会社 餐后高血糖改善剂
US6600011B2 (en) 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
FR2833169B1 (fr) * 2001-12-07 2004-07-16 Oreal Composition filtrante contenant un derive de 1,3,5-triazine, un derive du dibenzoylmethane, et un derive de 2-hydroxybenzophenone aminosubstitue
US7119120B2 (en) * 2001-12-26 2006-10-10 Genzyme Corporation Phosphate transport inhibitors
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
US7109184B2 (en) * 2002-03-19 2006-09-19 Genzyme Corporation Phosphate transport inhibitors
AT411463B (de) 2002-09-03 2004-01-26 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von alkylierten n- bzw. amino-, ammonium- oder spirobicyclischen ammoniumgruppen haltigen, vernetzten polymeren
AU2003282867A1 (en) * 2002-10-22 2004-05-13 Genzyme Corporation Amine polymers for promoting bone formation
AT412473B (de) 2003-01-15 2005-03-25 Dsm Fine Chem Austria Gmbh Verfahren zur kontinuierlichen trocknung von n- bzw. amino-, ammonium- oder spirobicyclische ammoniumgruppen haltigen polymeren
US7608674B2 (en) * 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US8426528B2 (en) * 2004-02-23 2013-04-23 E I Du Pont De Nemours And Company Preparation of crosslinked polymers containing biomass derived materials
EP1732973A1 (de) * 2004-02-23 2006-12-20 E.I.Du pont de nemours and company Aus biomasse gewonnene substanzen enthaltende vernetzte polymere
ES2397159T3 (es) 2004-03-26 2013-03-05 Mitsubishi Tanabe Pharma Corporation Agente mejorador de la resistencia a insulina
GB2456253B (en) 2004-03-30 2009-08-26 Relypsa Inc Ion binding polymers and uses thereof
US20050276781A1 (en) * 2004-06-09 2005-12-15 Ross Edward A Molecularly imprinted phosphate binders for therapeutic use
CA2579612A1 (en) * 2004-09-24 2006-04-06 Biosphere Medical, Inc. Microspheres capable of binding radioisotopes, optionally comprising metallic microparticles, and methods of use thereof
AU2005296290A1 (en) * 2004-10-13 2006-04-27 Ilypsa, Inc. Crosslinked amine polymers
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
JP4547620B2 (ja) * 2004-12-02 2010-09-22 日東紡績株式会社 架橋アリルアミン類重合体の製造方法
ITME20040015A1 (it) * 2004-12-07 2005-03-07 Vincenzo Savica Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
EP1830832A1 (de) * 2004-12-30 2007-09-12 Genzyme Corporation Zinkhaltige behandlungen für hyperphosphatämie
WO2006091901A1 (en) * 2005-02-23 2006-08-31 E.I. Dupont De Nemours And Company Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers
CA2601236A1 (en) * 2005-03-16 2006-09-21 Usv Limited An improved process for the preparation of crosslinked polyallylamine polymer
BRPI0615211A2 (pt) 2005-08-17 2013-01-15 Hills Pet Nutrition Inc composiÇço, mÉtodo para evitar ou tratar doenÇa renal ou para a melhora da funÇço renal, kit, e, meio para comunicar informaÇço sobre ou instruÇÕes para a mistura e administraÇço de um ou mais das composiÇÕes, componentes de composiÇço, composiÇÕes alimentÍcias, ingredientes alimentÍcios e medicamentos renais e para uso dos dispositivos de diagnàstico renal
JP2009507019A (ja) * 2005-09-02 2009-02-19 ジェンザイム・コーポレーション リン酸塩を除去する方法およびそれに使用される重合体
AR056499A1 (es) * 2005-09-06 2007-10-10 Serapis Farmaceuticals Ltd Compuestos
KR101574072B1 (ko) 2005-09-15 2015-12-04 젠자임 코포레이션 아민 중합체에 대한 샤셋 제형
AU2012205214B2 (en) * 2005-09-15 2015-05-21 Genzyme Corporation Formulation for Amine Polymers
CA2624112A1 (en) 2005-09-30 2007-04-05 Ilypsa, Inc. Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
JP2009510126A (ja) 2005-09-30 2009-03-12 レリプサ, インコーポレイテッド 哺乳類の胃腸管からカリウムイオンを選択的に除去するための方法および組成物
CA2626734A1 (en) * 2005-11-08 2007-05-18 Genzyme Corporation Magnesium-containing polymers for the treatment of hyperphosphatemia
EP1973587B1 (de) 2005-12-12 2019-02-06 AllAccem, Inc. Verfahren und systeme zur herstellung von antimikrobiellen filmen und überzügen
ITRM20060204A1 (it) * 2006-04-10 2007-10-11 Vincenzo Savica Farmaci e alimentei per diete normoproteiche iperproteiche ipopro teiche tutte ipofosforiche e bevande ipofosforiche
JP2009536246A (ja) * 2006-05-05 2009-10-08 ゲンズイメ コーポレーション ホスフェート捕捉剤としてのアミン縮合重合体
EP2039363B1 (de) 2006-06-16 2013-01-02 Mitsubishi Tanabe Pharma Corporation Mittel zur prävention und/oder behandlung von glomerulopathie
WO2008005217A2 (en) * 2006-07-05 2008-01-10 Genzyme Corporation Iron(ii)-containing treatments for hyperphosphatemia
CA2658338A1 (en) * 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
US20090252794A1 (en) 2006-08-09 2009-10-08 Tetsuya Suzuki Tablet
WO2008062437A2 (en) * 2006-09-01 2008-05-29 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
EP2066293A2 (de) 2006-09-29 2009-06-10 Genzyme Corporation Amid-dendrimer-zusammensetzungen
ES2573636T3 (es) 2006-10-25 2016-06-09 Wisconsin Alumni Research Foundation Métodos para reducir la absorción de fosfato empleando un anticuerpo anti-Npt2B
US20100143385A1 (en) 2006-10-26 2010-06-10 Mark Cook Methods for reducing phosphate absorption
WO2008076242A1 (en) * 2006-12-14 2008-06-26 Genzyme Corporation Amido-amine polymer compositions
JP2008169758A (ja) * 2007-01-11 2008-07-24 Bosch Corp ターボチャージャ駆動制御方法及びその装置
ES2522908T3 (es) 2007-02-21 2014-11-19 Allaccem, Inc. Composiciones a base de compuestos policíclicos con puente para la inhibición y el alivio de enfermedades
US20100129309A1 (en) * 2007-02-23 2010-05-27 Dhal Pradeep K Amine polymer compositions
US20100196305A1 (en) * 2007-03-08 2010-08-05 Dhal Pradeep K Sulfone polymer compositions
US8034833B2 (en) * 2008-03-20 2011-10-11 Biolink Life Sciences, Inc. Phosphorus binder for treatment of renal disease
WO2008133954A1 (en) * 2007-04-27 2008-11-06 Genzyme Corporation Amido-amine dendrimer compositions
US20100189679A1 (en) 2007-07-11 2010-07-29 Toray Industries, Inc. Crosslinked polyallylamine or acid addition salt thereof, and use thereof for medical purposes
EP2016947A1 (de) * 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Neuartiges Verfahren zur Herstellung vernetzter Poly(allylamin-)Polymere in einem einzigen Schritt
US8153617B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in humans
WO2009023544A2 (en) * 2007-08-10 2009-02-19 Ilypsa, Inc. Dosage unit anion-exchange polymer pharmaceutical compositions
US8188068B2 (en) * 2007-08-10 2012-05-29 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in pets
US8153618B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for topical applications for pets
US20090074833A1 (en) * 2007-08-17 2009-03-19 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling bone resorption
TWI468167B (zh) 2007-11-16 2015-01-11 威佛(國際)股份有限公司 藥學組成物
WO2009078958A1 (en) * 2007-12-14 2009-06-25 Genzyme Corporation Coated pharmaceutical compositions
US8389640B2 (en) * 2008-04-15 2013-03-05 Lupin Limited Process for the preparation of cross-linked polyallylamine polymer
WO2009154747A1 (en) * 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
US20100004218A1 (en) * 2008-06-20 2010-01-07 Whiteford Jeffery A Bridged polycyclic compound based compositions for renal therapy
US20100016270A1 (en) * 2008-06-20 2010-01-21 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling cholesterol levels
DE102008030046A1 (de) 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
US8404784B2 (en) * 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
US20100166861A1 (en) * 2008-12-29 2010-07-01 Kelly Noel Lynch Pharmaceutical formulations of sevalamer, or salts thereof, and copovidone
AU2010209293A1 (en) 2009-01-22 2011-09-08 Usv Limited Pharmaceutical compositions comprising phosphate-binding polymer
AU2010261339A1 (en) 2009-06-16 2012-01-19 Watson Pharma Private Limited Processes for the preparation of sevelamer carbonate
US8673272B2 (en) * 2009-07-27 2014-03-18 Isp Investments Inc. Ultraviolet-absorbing compounds
GB0921951D0 (en) * 2009-12-16 2010-02-03 Fujifilm Mfg Europe Bv Curable compositions and membranes
JP5377265B2 (ja) * 2009-12-16 2013-12-25 一般財団法人川村理化学研究所 ポリマー/酒石酸結晶性ナノ複合体及びその製造方法
ES2414383T5 (es) 2010-01-15 2016-12-12 Graphic Packaging International, Inc. Garra de cadena continua para cajas de cartón octogonales
EP2998329A3 (de) 2010-02-24 2016-04-06 Relypsa, Inc. Vernetztes polyvinylamin, polyallalamin und polyethylenimin zur verwendung als gallensäurekomplexbildner
JP5717422B2 (ja) * 2010-11-30 2015-05-13 株式会社パイロットコーポレーション ゲル状組成物の製造方法
IT1404163B1 (it) * 2011-02-01 2013-11-15 Chemi Spa Processo per la preparazione di poliallilamine reticolate o loro sali farmaceuticamente accettabili
DK2672945T3 (en) 2011-02-09 2016-03-21 Synthon Bv STABILIZED PACKAGING TYPES OF sevelamer.
CN102796262B (zh) * 2011-05-24 2014-11-12 北大方正集团有限公司 一种碳酸司维拉姆的制备方法
WO2013064193A1 (en) 2011-11-04 2013-05-10 Synthon Bv Pharmaceutical compositions comprising sevelamer
US20130123433A1 (en) 2011-11-14 2013-05-16 Formosa Laboratories, Inc. Method for preparing poly(allylamine) hydrochloride and derivatives therefrom
WO2013087237A1 (en) 2011-12-13 2013-06-20 Synthon Bv Purification of sevelamer and related polyallylamines
RU2014128587A (ru) 2011-12-13 2016-02-10 Синтон Б.В. Получение севеламера с пониженным содержанием аллиламина
CN102675510B (zh) * 2012-05-28 2014-04-02 诚达药业股份有限公司 司维拉姆的合成工艺
ES2471340B1 (es) 2012-12-21 2015-08-17 Laboratorios Rubió, S.A. Composición farmacéutica oral para fármacos de elevada posología
US9687573B2 (en) 2013-03-13 2017-06-27 Biosphere Medical, Inc. Compositions and associated methods for radioisotope-binding microparticles
CN103446179B (zh) * 2013-05-14 2017-03-15 厦门绿洲安源投资管理有限公司 作为磷酸盐、脂肪酸和胆汁酸绑定螯合剂的双亲聚富勒烯树状交联聚阳离子凝胶的应用
LT3003327T (lt) 2013-06-05 2017-12-27 Tricida Inc. Protonus surišantys polimerai, skirti geriamajam vartojimui
MX2017007497A (es) 2014-12-10 2017-10-04 Tricida Inc Polimeros de union a protones para administracion oral.
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
US10925893B2 (en) 2015-03-20 2021-02-23 Dazhi Yang Polysaccharide-polyamine copolymer and use thereof in reducing low density lipolipoprotein (LDL) concentration in plasma
EP3270934B1 (de) 2015-03-20 2022-12-21 Howard University Mikroträger, matrizen und gerüste zur kultivierung von säugerzellen und verfahren zur herstellung davon
US10245284B2 (en) 2015-08-19 2019-04-02 Alpex Pharma S.A. Granular composition for oral administration
DK3426608T3 (da) 2016-03-08 2021-08-09 Technion Res & Dev Foundation Desinfektion og fjernelse af nitrogenarter fra saltvands-akvakultursystemer
RU2018142943A (ru) 2016-05-06 2020-06-08 Трисида, Инк. Композиции для лечения нарушений кислотно-основного равновесия
EP3564292B1 (de) 2016-12-28 2021-06-16 FUJIFILM Corporation Emulsion eines stickstoffatomhaltigen polymers oder salz davon, herstellungsverfahren dafür und verfahren zur herstellung von partikeln
CN107412166B (zh) * 2017-08-08 2020-03-24 同济大学 一种纳米复合吸附磷材料及其制备与应用
US10934380B1 (en) 2017-09-25 2021-03-02 Tricida, Inc. Crosslinked poly(allylamine) polymer pharmaceutical compositions
CN111225674A (zh) * 2017-10-16 2020-06-02 富士胶片株式会社 高磷血症治疗剂
WO2019078198A1 (ja) 2017-10-16 2019-04-25 富士フイルム株式会社 高リン血症治療剤および粒子
US10479865B2 (en) 2017-11-01 2019-11-19 Strides Shasun Limited Process for the preparation of sevelamer carbonate
US11266684B2 (en) 2017-11-03 2022-03-08 Tricida, Inc. Compositions for and method of treating acid-base disorders
CN112047854B (zh) * 2020-10-20 2021-07-02 中国科学院长春应用化学研究所 一种n-乙烯基烷基酰胺的制备方法
EP4295836A1 (de) 2022-06-22 2023-12-27 Labomed Pharmaceutical Company S.A. Beutel mit einer flüssigen suspension eines sevelamersalzes
WO2024084076A1 (en) * 2022-10-20 2024-04-25 Universiteit Gent Method to prepare amidated polymers

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE580490A (fr) * 1958-07-15 1960-01-08 Merck & Co Inc Compositions et procédés pour abaisser la teneur en cholestérol du sang
US3308020A (en) * 1961-09-22 1967-03-07 Merck & Co Inc Compositions and method for binding bile acids in vivo including hypocholesteremics
US3332841A (en) * 1961-10-04 1967-07-25 Lilly Co Eli Method of treating hyperacidity
DE1927336A1 (de) * 1968-06-17 1969-12-18 Upjohn Co Orale Dosierungsform zur Bekaempfung von Hypercholesterinaemie
US3980770A (en) * 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
CH604722A5 (de) * 1973-02-09 1978-09-15 Sandoz Ag
AR206115A1 (es) * 1973-06-11 1976-06-30 Merck & Co Inc Procedimiento para preparar un polimero lineal no ramificado y no reticulado
US4205064A (en) * 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
US4016209A (en) * 1975-04-23 1977-04-05 Merck & Co., Inc. 3-[N'-(3-Halopropyl)-N-'-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof
US4181718A (en) * 1975-12-29 1980-01-01 Mason Norbert S Polyanion-stabilized aluminum hydrogels
US4071478A (en) * 1976-06-07 1978-01-31 Merck & Co., Inc. Controlled partially cross-linked 3,3-ionenes
DE2741323A1 (de) * 1977-03-10 1978-09-14 Werner Klaus Konzack Raederfahrzeug
US4143130A (en) * 1977-08-29 1979-03-06 Warren-Teed Laboratories, Inc. Method for treating kidney stones
JPS5566513A (en) * 1978-11-14 1980-05-20 Ono Pharmaceut Co Ltd Drug for arteriosclerosis comprising high polymer compound as active constituent
US4247393A (en) * 1979-01-11 1981-01-27 Wallace Richard A Hemodialysis assist device
DE3169753D1 (en) * 1980-12-12 1985-05-09 Smith & Nephew Ass Polymers, preparation and use
JPS6090243A (ja) * 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
DE3572985D1 (en) * 1984-05-11 1989-10-19 Bristol Myers Co Novel bile sequestrant resin and uses
US4631305A (en) * 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
JPS62132830A (ja) * 1985-12-05 1987-06-16 Teijin Ltd 徐放性医薬品組成物
DE68913602T2 (de) * 1988-07-13 1994-06-16 Collaborative Biomed Prod Gewebe-Immobilisierungs- und Zellkultursystem und Verfahren zum Anbringen biologisch wirksamer Teile an einem Substrat.
EP0429541B1 (de) * 1988-08-26 1993-12-01 The Upjohn Company Feinkörniges colestipol hydrochlorid
GB8829835D0 (en) * 1988-12-21 1989-02-15 Smith Kline French Lab Compounds
DE3901527A1 (de) * 1989-01-20 1990-07-26 Hoechst Ag Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate
US5053423A (en) * 1990-03-22 1991-10-01 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
JPH0687974B2 (ja) * 1990-03-27 1994-11-09 忠一 平山 発熱物質の吸着材料
JPH0424180A (ja) * 1990-05-16 1992-01-28 Daikin Ind Ltd クローラ式小型運搬機
AU659106B2 (en) * 1990-11-06 1995-05-11 Fgn, Inc. Method for treating colonic polyps by the use of esters and amides of substituted phenyl and pyridyl amino carboxylates
IE914179A1 (en) * 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
JP2785529B2 (ja) * 1991-08-21 1998-08-13 日東紡績株式会社 エタノール徐放剤およびそれを用いた食品保存用組成物
EP0534304A1 (de) * 1991-09-21 1993-03-31 Hoechst Aktiengesellschaft Cycloalkylierte Polyethyleniminderivate und ihre Verwendung als Hypolipidämika
SE470006B (sv) * 1991-09-26 1993-10-25 Corline Systems Ab Nytt konjugat, dess framställning och användning samt substrat preparerat med konjugatet
WO1993014127A1 (en) * 1992-01-21 1993-07-22 University Of Utah Method and composition for heparin binding using polyaminocations covalently immobilised on polymeric surfaces with polyethylene oxide spacers
WO1993022380A1 (en) * 1992-05-06 1993-11-11 Isp Investments Inc. Polymers of vinyl-pyrrolidone and aminoalkyl acrylamides
DE4227019A1 (de) * 1992-08-14 1994-02-17 Geckeler Kurt E Priv Doz Dr Herstellung und Modifikation von Materialien auf der Basis von Amino- oder Amidpolymeren
WO1994004596A1 (en) * 1992-08-20 1994-03-03 E.I. Du Pont De Nemours And Company Crosslinked polymeric ammonium salts
US5302531A (en) * 1992-10-22 1994-04-12 Miles Inc. Composition for the semiquantitative determination of specific gravity of a test sample
EP0684958B1 (de) * 1993-02-17 1998-06-10 Btg International Limited 1 guanidino gruppen enthaltende polymere zur verwendung in der therapie
WO1994027620A1 (en) * 1993-06-02 1994-12-08 Geltex Pharmaceuticals, Inc. Compositions and process for removing bile salts

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WO1995005184A3 (en) 1995-03-23
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PT716606E (pt) 2002-02-28
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