ATE163230T1 - Makromolekulare mikropartikel und verfahren zu ihrer herstellung - Google Patents
Makromolekulare mikropartikel und verfahren zu ihrer herstellungInfo
- Publication number
- ATE163230T1 ATE163230T1 AT94910826T AT94910826T ATE163230T1 AT E163230 T1 ATE163230 T1 AT E163230T1 AT 94910826 T AT94910826 T AT 94910826T AT 94910826 T AT94910826 T AT 94910826T AT E163230 T1 ATE163230 T1 AT E163230T1
- Authority
- AT
- Austria
- Prior art keywords
- microparticles
- production
- dehydrating agent
- microparticle composition
- macromolecular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2823793A | 1993-03-09 | 1993-03-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE163230T1 true ATE163230T1 (de) | 1998-02-15 |
Family
ID=21842313
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94910826T ATE163230T1 (de) | 1993-03-09 | 1994-03-04 | Makromolekulare mikropartikel und verfahren zu ihrer herstellung |
AT97112821T ATE258685T1 (de) | 1993-03-09 | 1994-03-04 | Makromolekulare mikropartikel und verfahren zur ihrer herstellung |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97112821T ATE258685T1 (de) | 1993-03-09 | 1994-03-04 | Makromolekulare mikropartikel und verfahren zur ihrer herstellung |
Country Status (11)
Country | Link |
---|---|
US (1) | US5578709A (de) |
EP (2) | EP0809110B1 (de) |
JP (5) | JPH08507806A (de) |
AT (2) | ATE163230T1 (de) |
AU (1) | AU6358594A (de) |
CA (1) | CA2157793C (de) |
DE (2) | DE69433523T2 (de) |
DK (1) | DK0809110T3 (de) |
ES (2) | ES2215207T3 (de) |
PT (1) | PT809110E (de) |
WO (1) | WO1994020856A1 (de) |
Families Citing this family (134)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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US6197333B1 (en) | 1996-03-28 | 2001-03-06 | The Board Of Trustees Of The University Of Illinois | Materials and methods for making improved liposome compositions |
US6217886B1 (en) | 1997-07-14 | 2001-04-17 | The Board Of Trustees Of The University Of Illinois | Materials and methods for making improved micelle compositions |
SE512663C2 (sv) | 1997-10-23 | 2000-04-17 | Biogram Ab | Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer |
CN1714783A (zh) | 1998-03-06 | 2006-01-04 | 生物领域医疗公司 | 用于组织膨胀和治疗的可植入颗粒 |
US6660301B1 (en) * | 1998-03-06 | 2003-12-09 | Biosphere Medical, Inc. | Injectable microspheres for dermal augmentation and tissue bulking |
US20070009605A1 (en) * | 1998-07-23 | 2007-01-11 | Ignatious Francis X | Encapsulation of water soluble peptides |
US6270700B1 (en) | 1998-07-23 | 2001-08-07 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Encapsulation of water soluble peptides |
WO2000004916A1 (en) * | 1998-07-23 | 2000-02-03 | Societe De Conseils De Recherches Et D'applications Scientifiques Sas | Encapsulation of water soluble peptides |
FR2784580B1 (fr) | 1998-10-16 | 2004-06-25 | Biosepra Inc | Microspheres de polyvinyl-alcool et procedes de fabrication de celles-ci |
EP1074248A1 (de) * | 1999-07-08 | 2001-02-07 | Arnold Hilgers | Verabreichungssystem für biologisches Material |
US6822086B1 (en) * | 1999-08-09 | 2004-11-23 | The General Hospital Corporation | Drug-carrier complexes and methods of use thereof |
US8106098B2 (en) * | 1999-08-09 | 2012-01-31 | The General Hospital Corporation | Protein conjugates with a water-soluble biocompatible, biodegradable polymer |
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EP1267946A4 (de) | 2000-02-28 | 2008-07-02 | Genesegues Inc | Nanokapsel-einkapselungs-system und verfahren |
US7338657B2 (en) * | 2001-03-15 | 2008-03-04 | Biosphere Medical, Inc. | Injectable microspheres for tissue construction |
US6436424B1 (en) | 2000-03-20 | 2002-08-20 | Biosphere Medical, Inc. | Injectable and swellable microspheres for dermal augmentation |
WO2001070289A2 (en) | 2000-03-20 | 2001-09-27 | Biosphere Medical, Inc. | Injectable and swellable microspheres for tissue bulking |
ES2551164T3 (es) | 2000-03-24 | 2015-11-16 | Biosphere Medical, Inc. | Microesferas para embolización activa |
SE517422C2 (sv) | 2000-10-06 | 2002-06-04 | Bioglan Ab | Farmaceutiskt acceptabel stärkelse |
SE517421C2 (sv) | 2000-10-06 | 2002-06-04 | Bioglan Ab | Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav |
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ES2326209T3 (es) | 2000-10-27 | 2009-10-05 | Baxter Healthcare S.A. | Produccion de microesferas. |
SE518007C2 (sv) | 2000-11-16 | 2002-08-13 | Bioglan Ab | Förfarande för framställning av mikropartiklar |
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-
1994
- 1994-03-04 CA CA002157793A patent/CA2157793C/en not_active Expired - Lifetime
- 1994-03-04 EP EP97112821A patent/EP0809110B1/de not_active Expired - Lifetime
- 1994-03-04 WO PCT/US1994/002316 patent/WO1994020856A1/en active IP Right Grant
- 1994-03-04 JP JP6520171A patent/JPH08507806A/ja not_active Withdrawn
- 1994-03-04 DK DK97112821T patent/DK0809110T3/da active
- 1994-03-04 ES ES97112821T patent/ES2215207T3/es not_active Expired - Lifetime
- 1994-03-04 US US08/206,456 patent/US5578709A/en not_active Expired - Lifetime
- 1994-03-04 AT AT94910826T patent/ATE163230T1/de active
- 1994-03-04 EP EP94910826A patent/EP0688429B1/de not_active Expired - Lifetime
- 1994-03-04 ES ES94910826T patent/ES2113094T3/es not_active Expired - Lifetime
- 1994-03-04 DE DE69433523T patent/DE69433523T2/de not_active Expired - Lifetime
- 1994-03-04 DE DE69408527T patent/DE69408527T2/de not_active Expired - Lifetime
- 1994-03-04 PT PT97112821T patent/PT809110E/pt unknown
- 1994-03-04 AU AU63585/94A patent/AU6358594A/en not_active Abandoned
- 1994-03-04 AT AT97112821T patent/ATE258685T1/de active
-
2004
- 2004-06-01 JP JP2004163547A patent/JP2004323528A/ja not_active Withdrawn
-
2005
- 2005-06-20 JP JP2005179651A patent/JP2006023297A/ja not_active Withdrawn
-
2007
- 2007-03-05 JP JP2007054936A patent/JP2007212464A/ja active Pending
- 2007-05-16 JP JP2007131091A patent/JP2007297633A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2157793A1 (en) | 1994-09-15 |
ATE258685T1 (de) | 2004-02-15 |
EP0809110A1 (de) | 1997-11-26 |
EP0688429B1 (de) | 1998-02-11 |
PT809110E (pt) | 2004-06-30 |
DE69433523T2 (de) | 2004-12-23 |
EP0809110B1 (de) | 2004-01-28 |
DE69408527D1 (de) | 1998-03-19 |
JP2007297633A (ja) | 2007-11-15 |
JP2006023297A (ja) | 2006-01-26 |
EP0688429A1 (de) | 1995-12-27 |
US5578709A (en) | 1996-11-26 |
ES2113094T3 (es) | 1998-04-16 |
JPH08507806A (ja) | 1996-08-20 |
DE69408527T2 (de) | 1998-06-04 |
JP2007212464A (ja) | 2007-08-23 |
AU6358594A (en) | 1994-09-26 |
DK0809110T3 (da) | 2004-05-24 |
ES2215207T3 (es) | 2004-10-01 |
DE69433523D1 (de) | 2004-03-04 |
JP2004323528A (ja) | 2004-11-18 |
CA2157793C (en) | 1999-07-13 |
WO1994020856A1 (en) | 1994-09-15 |
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