AT381307B - Verfahren zum herstellen neuer carbostyrilderivate und ihrer pharmazeutisch annehmbaren salze - Google Patents

Verfahren zum herstellen neuer carbostyrilderivate und ihrer pharmazeutisch annehmbaren salze

Info

Publication number
AT381307B
AT381307B AT0098481A AT98481A AT381307B AT 381307 B AT381307 B AT 381307B AT 0098481 A AT0098481 A AT 0098481A AT 98481 A AT98481 A AT 98481A AT 381307 B AT381307 B AT 381307B
Authority
AT
Austria
Prior art keywords
pharmaceutically acceptable
acceptable salts
producing new
carbostyrile
derivatives
Prior art date
Application number
AT0098481A
Other languages
German (de)
English (en)
Other versions
ATA98481A (de
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2880580A external-priority patent/JPS56125370A/ja
Priority claimed from JP11502280A external-priority patent/JPS5738772A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Priority to AT0054184A priority Critical patent/AT387215B/de
Publication of ATA98481A publication Critical patent/ATA98481A/de
Application granted granted Critical
Publication of AT381307B publication Critical patent/AT381307B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT0098481A 1980-03-06 1981-03-03 Verfahren zum herstellen neuer carbostyrilderivate und ihrer pharmazeutisch annehmbaren salze AT381307B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0054184A AT387215B (de) 1980-03-06 1984-02-17 Verfahren zum herstellen neuer carbostyrilderivate und ihrer salze

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2880580A JPS56125370A (en) 1980-03-06 1980-03-06 Carbostyril derivative
JP11502280A JPS5738772A (en) 1980-08-20 1980-08-20 Carbostyril derivative

Publications (2)

Publication Number Publication Date
ATA98481A ATA98481A (de) 1986-02-15
AT381307B true AT381307B (de) 1986-09-25

Family

ID=26366952

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0098481A AT381307B (de) 1980-03-06 1981-03-03 Verfahren zum herstellen neuer carbostyrilderivate und ihrer pharmazeutisch annehmbaren salze

Country Status (21)

Country Link
US (4) US4567187A (enExample)
AT (1) AT381307B (enExample)
AU (1) AU523005B2 (enExample)
BE (1) BE887800A (enExample)
CA (1) CA1155119A (enExample)
CH (1) CH647775A5 (enExample)
DE (2) DE3152880C2 (enExample)
DK (1) DK155282C (enExample)
ES (4) ES8301962A1 (enExample)
FI (1) FI76323C (enExample)
FR (1) FR2477542A1 (enExample)
GB (1) GB2071094B (enExample)
IT (1) IT1144315B (enExample)
MX (1) MX6980E (enExample)
NL (1) NL184364C (enExample)
NO (1) NO159531C (enExample)
PH (1) PH17194A (enExample)
PT (1) PT72622B (enExample)
RU (1) RU1779249C (enExample)
SE (1) SE447255B (enExample)
SU (1) SU1367857A3 (enExample)

Families Citing this family (57)

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PH17194A (en) * 1980-03-06 1984-06-19 Otsuka Pharma Co Ltd Novel carbostyril derivatives,and pharmaceutical composition containing the same
FI77852C (fi) * 1981-02-17 1989-05-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat.
AU532361B2 (en) * 1981-09-01 1983-09-29 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
FI80022C (fi) * 1982-07-05 1990-04-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat.
CH655110A5 (de) * 1982-09-03 1986-03-27 Otsuka Pharma Co Ltd Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten.
DE3434271A1 (de) * 1984-09-19 1986-03-20 Beiersdorf Ag, 2000 Hamburg Substituierte 3,4-dihydro-chinolin-2(1h)-one verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
DE3509131A1 (de) * 1985-03-14 1986-09-18 Fa. Carl Zeiss, 7920 Heidenheim Verfahren zur justierten montage der optischen bauteile eines optischen geraetes
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JPH0696555B2 (ja) * 1986-07-31 1994-11-30 大塚製薬株式会社 カルボスチリル誘導体
DE3802030A1 (de) * 1988-01-25 1989-07-27 Hoechst Ag Makroporoese, asymmetrische, hydrophile membran aus polyaramid
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US5147881A (en) * 1990-11-14 1992-09-15 Pfizer Inc 4-(1,2-benzisoxazolyl)piperidine antipsychotic agents
US5166367A (en) * 1991-06-21 1992-11-24 American Home Products Corporation Antipsychotic benzodioxan derivatives
US5189171A (en) * 1991-06-21 1993-02-23 American Home Products Corporation Antipsychotic benzodioxan derivatives
AU655840B2 (en) * 1991-07-17 1995-01-12 Pfizer Inc. 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents
US6255322B1 (en) 1992-06-19 2001-07-03 Pfizer Inc. 2-(4-hydroxypiperidino)-1-alkanol derivatives as antiischemic agents
CN1052224C (zh) * 1993-04-07 2000-05-10 大塚制药株式会社 哌啶衍生物、含有它的外周血管舒张剂及其应用
ATE174915T1 (de) * 1994-10-31 1999-01-15 Merck Patent Gmbh Benzylpiperidinderivate mit hoher affinität zu bindungsstellen von aminosäure-rezeptoren
ZA9610741B (en) 1995-12-22 1997-06-24 Warner Lambert Co 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
DE19812331A1 (de) * 1998-03-20 1999-09-23 Merck Patent Gmbh Piperidinderivate
FR2823749B1 (fr) 2001-04-20 2004-02-20 Sanofi Synthelabo Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant
MY129350A (en) * 2001-04-25 2007-03-30 Bristol Myers Squibb Co Aripiprazole oral solution
DE10210779A1 (de) * 2002-03-12 2003-10-09 Merck Patent Gmbh Cyclische Amide
CA2476583C (en) * 2002-03-13 2011-07-05 Kristof Van Emelen Aminocarbonyl-derivatives as novel inhibitors of histone deacetylase
JP4648628B2 (ja) 2002-03-13 2011-03-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ヒストンデアセチラーゼの新規な阻害剤としてのカルボニルアミノ誘導体
WO2003076401A1 (en) 2002-03-13 2003-09-18 Janssen Pharmaceutica N.V. Sulfonylamino-derivatives as novel inhibitors of histone deacetylase
CN100396679C (zh) * 2002-03-13 2008-06-25 詹森药业有限公司 用作组蛋白脱乙酰化酶抑制剂的哌嗪基、哌啶基和吗啉基衍生物
MY142362A (en) * 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis
ME01058B (me) * 2004-07-28 2012-10-20 Janssen Pharmaceutica Nv Supstituisani derivati propenil piperazina kao novi inhibitori histonske deacetilaze
HRP20120327T1 (hr) 2004-07-28 2012-05-31 Janssen Pharmaceutica Nv Supstituirani indolil alkil amino derivati kao novi inhibitori histonske deacetilaze
PT1776358E (pt) * 2004-07-28 2009-08-13 Janssen Pharmaceutica Nv Derivados de propenilpiperazina substituída como novos inibidores de histona-desacetilase
TWI320783B (en) 2005-04-14 2010-02-21 Otsuka Pharma Co Ltd Heterocyclic compound
DK1885710T3 (en) 2005-05-18 2015-11-23 Janssen Pharmaceutica Nv SUBSTITUTED AMINOPROPENYLPIPERIDINE OR MORPHOLINE DERIVATIVES AS UNKNOWN INHIBITORS OF HISTONDEACETYLASE
EP1979327A1 (en) * 2006-01-19 2008-10-15 Janssen Pharmaceutica, N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
DK1981875T3 (da) * 2006-01-19 2014-07-14 Janssen Pharmaceutica Nv Substituerede indolylalkylaminoderivater som inhibitorer af histondeacetylase
EP1979326B1 (en) 2006-01-19 2012-10-03 Janssen Pharmaceutica N.V. Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
ES2327972T3 (es) * 2006-01-19 2009-11-05 Janssen Pharmaceutica, N.V. Derivados de aminofenil como nuevos inhibidores de histona deacetilasa.
EP2520567A3 (en) * 2006-02-23 2012-12-12 Shionogi & Co., Ltd. Nitrogen-containing heterocycle derivatives substituted with cyclic group
WO2009034029A2 (de) * 2007-09-07 2009-03-19 Boehringer Ingelheim International Gmbh 1-substituierte 4 -heterocyclylpiperidine als cgrp antagonisten
CN102413830A (zh) 2009-02-26 2012-04-11 雷维瓦药品公司 利用芳基哌嗪衍生物的组合物、合成及方法
WO2013169964A1 (en) * 2012-05-09 2013-11-14 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof
CN106608875A (zh) 2015-10-26 2017-05-03 江苏恩华药业股份有限公司 一种稠和杂环类衍生物合成及其应用
CN108031471A (zh) * 2017-10-27 2018-05-15 苏州盖德精细材料有限公司 一种静电纺丝制备的负载型纳米纤维催化剂及其在3,5-二羟基甲苯制备中的应用
CN108250058B (zh) * 2018-01-19 2022-02-11 上海怡立舍生物技术有限公司 Ppar激动剂及其在治疗老年痴呆及其他疾病中的用途
CN116554127B (zh) * 2022-01-28 2025-03-21 成都麻沸散医药科技有限公司 哌嗪取代苯酚类衍生物及其用途

Family Cites Families (33)

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US3629266A (en) * 1969-03-03 1971-12-21 Miles Lab (phenyl piperidino alkyl)3 4-dihydrocarbostyrils
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
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JPS6026797B2 (ja) * 1976-07-12 1985-06-25 大塚製薬株式会社 新規なカルボスチリル誘導体
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FI77852C (fi) * 1981-02-17 1989-05-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat.
AU532361B2 (en) * 1981-09-01 1983-09-29 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives

Also Published As

Publication number Publication date
AU523005B2 (en) 1982-07-08
US4460593A (en) 1984-07-17
ES8405782A1 (es) 1984-06-16
MX6980E (es) 1987-01-19
RU1779249C (ru) 1992-11-30
ES500137A0 (es) 1982-11-01
FI76323C (fi) 1988-10-10
ES518667A0 (es) 1984-06-16
NO159531C (no) 1989-01-11
SU1367857A3 (ru) 1988-01-15
US4619932A (en) 1986-10-28
SE447255B (sv) 1986-11-03
ATA98481A (de) 1986-02-15
CA1155119A (en) 1983-10-11
NL184364C (nl) 1989-07-03
DK99781A (da) 1981-09-07
PT72622B (en) 1982-06-15
FR2477542A1 (fr) 1981-09-11
NL8101099A (nl) 1981-10-01
DE3152880C2 (enExample) 1990-03-22
NO159531B (no) 1988-10-03
NO810765L (no) 1981-09-07
FI76323B (fi) 1988-06-30
ES8301962A1 (es) 1982-11-01
ES8305356A1 (es) 1983-04-01
PH17194A (en) 1984-06-19
ES8306141A1 (es) 1983-05-01
NL184364B (nl) 1989-02-01
BE887800A (fr) 1981-09-07
DK155282C (da) 1989-08-07
DE3107601C2 (enExample) 1989-07-20
DE3107601A1 (de) 1982-02-04
DK155282B (da) 1989-03-20
AU6797381A (en) 1981-09-10
GB2071094B (en) 1984-09-26
ES509659A0 (es) 1983-05-01
IT8167311A0 (it) 1981-03-05
US4567187A (en) 1986-01-28
US4455422A (en) 1984-06-19
SE8101409L (sv) 1981-09-07
IT1144315B (it) 1986-10-29
ES509658A0 (es) 1983-04-01
FR2477542B1 (enExample) 1983-09-09
PT72622A (en) 1981-04-01
GB2071094A (en) 1981-09-16
CH647775A5 (de) 1985-02-15
FI810669L (fi) 1981-09-07

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ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties