AR100293A2 - Soluciones de meloxicam estables muy concentradas - Google Patents

Soluciones de meloxicam estables muy concentradas

Info

Publication number
AR100293A2
AR100293A2 ARP140103015A ARP140103015A AR100293A2 AR 100293 A2 AR100293 A2 AR 100293A2 AR P140103015 A ARP140103015 A AR P140103015A AR P140103015 A ARP140103015 A AR P140103015A AR 100293 A2 AR100293 A2 AR 100293A2
Authority
AR
Argentina
Prior art keywords
concentrated stable
meloxicam
meloxicam solutions
stable meloxicam
solutions
Prior art date
Application number
ARP140103015A
Other languages
English (en)
Inventor
Prof Dr Prox Axel
Dr Daneck Klaus
A Dr Folger Martin
Kroff Hans
Juergen - Hassel Bernhard
Dr Kruss Bernd
Dr Henke Stefan
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7646375&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR100293(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of AR100293A2 publication Critical patent/AR100293A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Solución acuosa de meloxicam, administrable por vía oral o parenteral y exenta de ciclodextrina, que contiene una sal de meloxicam farmacológicamente compatible de una base orgánica o inorgánica y uno o más coadyuvantes adecuados, encontrándose el contenido en sal de meloxicam disuelta por encima de 10 mg/ml.
ARP140103015A 2000-06-20 2014-08-12 Soluciones de meloxicam estables muy concentradas AR100293A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10030345A DE10030345A1 (de) 2000-06-20 2000-06-20 Hochkonzentrierte stabile Meloxicamlösungen

Publications (1)

Publication Number Publication Date
AR100293A2 true AR100293A2 (es) 2016-09-28

Family

ID=7646375

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP010102932A AR028967A1 (es) 2000-06-20 2001-06-20 Soluciones de meloxicam estables muy concentradas
ARP140103015A AR100293A2 (es) 2000-06-20 2014-08-12 Soluciones de meloxicam estables muy concentradas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP010102932A AR028967A1 (es) 2000-06-20 2001-06-20 Soluciones de meloxicam estables muy concentradas

Country Status (31)

Country Link
EP (1) EP1299107B1 (es)
JP (2) JP2003535902A (es)
KR (1) KR100805651B1 (es)
CN (1) CN1236774C (es)
AR (2) AR028967A1 (es)
AT (1) ATE297736T1 (es)
AU (2) AU8185201A (es)
BG (1) BG65798B1 (es)
CA (1) CA2414063C (es)
CZ (1) CZ302717B6 (es)
DE (2) DE10030345A1 (es)
EA (1) EA005765B1 (es)
EC (1) ECSP024371A (es)
EE (1) EE04930B1 (es)
ES (1) ES2244643T3 (es)
HR (1) HRP20021011B1 (es)
HU (1) HU229184B1 (es)
IL (2) IL153114A0 (es)
ME (1) ME00253B (es)
MX (1) MXPA02012732A (es)
MY (1) MY137729A (es)
NO (1) NO330199B1 (es)
NZ (1) NZ523583A (es)
PT (1) PT1299107E (es)
RS (1) RS50142B (es)
SK (1) SK286938B6 (es)
TW (1) TWI250018B (es)
UA (1) UA73584C2 (es)
UY (1) UY26781A1 (es)
WO (1) WO2001097813A2 (es)
ZA (1) ZA200209989B (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
EP1348436A1 (en) * 2002-03-30 2003-10-01 Boehringer Ingelheim International GmbH Meloxicam suppositories
JP4707316B2 (ja) * 2002-10-11 2011-06-22 ロート製薬株式会社 水性液状組成物
DE10250081A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Vetmedica Gmbh Wasserlösliche Meloxicam Granulate
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004025324A1 (de) * 2004-05-19 2005-12-08 Boehringer Ingelheim Vetmedica Gmbh Flüssige Zubereitung für die Veterinärmedizin, Verfahren zu deren Herstellung und deren Verwendung
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
ES2313452T3 (es) * 2004-12-06 2009-03-01 Janssen Pharmaceutica Nv Suspension oral que comprende meloxicam.
EP2767163A1 (en) 2005-02-17 2014-08-20 Abbott Laboratories Transmucosal administration of drug compositions for treating and preventing disorders in animals
RU2383344C2 (ru) * 2008-01-22 2010-03-10 Закрытое Акционерное Общество "Канонфарма Продакшн" Фармацевтический раствор мелоксикама и глицина, способ его получения и способ лечения
CN101584696A (zh) * 2008-05-21 2009-11-25 上海艾力斯医药科技有限公司 包含喹唑啉衍生物的组合物及制备方法、用途
TR200809200A1 (tr) 2008-12-01 2009-12-21 Sanovel �La� Sanay� Ve T�Caret Anon�M ��Rket� Meloksikam içeren farmasötik formülasyonlar
PL4378443T3 (pl) 2009-10-12 2025-09-08 Boehringer Ingelheim Vetmedica Gmbh Pojemniki na kompozycje zawierające meloksykam
CA2791805A1 (en) 2010-03-03 2011-09-09 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
KR101045052B1 (ko) * 2011-01-18 2011-06-28 지수광 자세교정용 발받침대
CN102908310A (zh) * 2012-11-02 2013-02-06 青岛康地恩药业股份有限公司 一种犬、猫用治疗类风湿性关节炎的美洛昔康注射液
CN104983686A (zh) * 2015-07-13 2015-10-21 胡涵 畜禽用美洛昔康可溶性粉剂及其制备方法
CN105213402B (zh) * 2015-09-30 2018-12-18 洛阳市兽药厂 一种畜禽复方恩诺沙星美洛昔康可溶性粉
HUE070065T2 (hu) * 2017-05-10 2025-05-28 Axsome Therapeutics Inc Gyógyszerkészítmények, amelyek meloxikámot tartalmaznak
CN113925830B (zh) * 2017-08-24 2023-07-14 江苏恒瑞医药股份有限公司 一种包含美洛昔康的可注射的药物组合物及其制备方法
KR20190107481A (ko) * 2018-03-12 2019-09-20 충북대학교 산학협력단 멜록시캄을 포함하는 구강붕해필름 제조방법 및 이에 의해 제조된 멜록시캄을 포함하는 구강붕해필름
JP7374501B2 (ja) * 2018-05-11 2023-11-07 南京清普生物科技有限公司 メロキシカム組成物、製剤及びその製造方法と応用
CN112823786A (zh) * 2019-11-21 2021-05-21 北京泰德制药股份有限公司 一种含有美洛昔康的药物组合物及应用
WO2021224815A1 (en) * 2020-05-06 2021-11-11 Cadila Healthcare Limited Stable aqueous parenteral solutions of nonsteroidal anti-inflammatory drug (nsaid)
CN115068419A (zh) * 2022-07-22 2022-09-20 潍坊恒邦兽药有限公司 兽用高浓度美洛昔康注射剂及其加工设备

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2756113A1 (de) 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE3217315C2 (de) * 1982-05-08 1986-05-22 Gödecke AG, 1000 Berlin Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten
JPS61501566A (ja) * 1984-03-14 1986-07-31 コルビエ−ル　ジエロ−ム 有効成分の可溶化法およびそれにより得られる薬理組成物
DE3437232A1 (de) * 1984-10-10 1986-04-17 Mack Chem Pharm Stabilisierte injektionsloesungen von piroxicam
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
IT1216686B (it) * 1988-04-01 1990-03-08 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione.
JPH0418022A (ja) * 1990-05-10 1992-01-22 Fujikawa Kk ピロキシカムの安定水溶液ならびにその製造法
HU205550B (en) * 1990-11-27 1992-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pyroxycam solution of increased stability, free from effects damaging tussues
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
ATA156496A (de) * 1996-09-03 1997-10-15 Nycomed Austria Gmbh Pharmazeutische zusammensetzung
EP0945134A1 (de) * 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
AU754064B2 (en) * 1998-05-15 2002-11-07 Wakamoto Pharmaceutical Co., Ltd. Anti-inflammatory eye drops
WO2001037838A1 (en) * 1999-11-24 2001-05-31 Wakamoto Pharmaceutical Co., Ltd. Ophthalmic aqueous preparation
KR200182299Y1 (ko) * 1999-12-08 2000-05-15 장지일 플로스 케이스를 포함하는 플로스 홀더
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen

Also Published As

Publication number Publication date
UA73584C2 (en) 2005-08-15
AU8185201A (en) 2002-01-02
EE200200701A (et) 2004-08-16
AR028967A1 (es) 2003-05-28
EA005765B1 (ru) 2005-06-30
HU229184B1 (en) 2013-09-30
HRP20021011A2 (en) 2005-02-28
MXPA02012732A (es) 2004-09-10
KR20030013447A (ko) 2003-02-14
MEP39808A (en) 2011-02-10
ECSP024371A (es) 2003-02-06
NO330199B1 (no) 2011-03-07
KR100805651B1 (ko) 2008-02-26
CN1437472A (zh) 2003-08-20
ME00253B (me) 2011-05-10
EP1299107B1 (en) 2005-06-15
PT1299107E (pt) 2005-08-31
NZ523583A (en) 2004-09-24
BG107347A (bg) 2003-09-30
CN1236774C (zh) 2006-01-18
CA2414063C (en) 2008-06-17
TWI250018B (en) 2006-03-01
RS50142B (sr) 2009-03-25
IL153114A0 (en) 2003-06-24
DE60111529D1 (de) 2005-07-21
ZA200209989B (en) 2003-10-08
JP2003535902A (ja) 2003-12-02
SK17992002A3 (sk) 2003-04-01
SK286938B6 (sk) 2009-07-06
AU2001281852B2 (en) 2006-04-13
PL359553A1 (en) 2004-08-23
WO2001097813A2 (en) 2001-12-27
ATE297736T1 (de) 2005-07-15
DE60111529T2 (de) 2005-12-15
IL153114A (en) 2011-07-31
EP1299107A2 (en) 2003-04-09
JP5330347B2 (ja) 2013-10-30
EA200201254A1 (ru) 2003-06-26
CZ20024191A3 (cs) 2003-04-16
UY26781A1 (es) 2002-01-31
NO20026132L (no) 2003-02-11
HK1057859A1 (en) 2004-04-23
DE10030345A1 (de) 2002-01-10
MY137729A (en) 2009-03-31
HRP20021011B1 (en) 2006-02-28
BG65798B1 (bg) 2009-12-31
JP2010280726A (ja) 2010-12-16
CZ302717B6 (cs) 2011-09-21
CA2414063A1 (en) 2001-12-27
ES2244643T3 (es) 2005-12-16
NO20026132D0 (no) 2002-12-19
WO2001097813A3 (en) 2002-05-10
HUP0300854A2 (hu) 2003-08-28
EE04930B1 (et) 2007-12-17
YU96402A (sh) 2006-01-16

Similar Documents

Publication Publication Date Title
AR100293A2 (es) Soluciones de meloxicam estables muy concentradas
UY27575A1 (es) Soluciones de metolixicam estables y muy concentradas para la inyección sin aguja
SV2002000586A (es) Formula de dosificacion de la droga accionada por hidrogel ref. pc11095/700006/b
PA8508701A1 (es) Composiciones farmaceuticas que proporcionan concentraciones potenciadas de farmaco
CO5261589A1 (es) Compuestos heterociclicos, su produccion y su utilizacion
CO5700797A2 (es) Composicion de farmaco conjugado
BR0209198A (pt) Métodos de sìntese de compostos contendo fenol
CA2521509A1 (en) Fast dissolving orally consumable films containing pharmaceutically active agents
AR024159A1 (es) Nuevo uso de compuestos como agentes antibacterianos
GT200000222A (es) Forma de dosificacion de farmacos accionada por un hidrogel.
ES2192101T3 (es) Formas cristalinas de eto2c-ch2-(r)cgl-aze-pab-oh.
ATE552838T1 (de) Wässrige lösung mit aminoglykosid-antibiotikum und bromfenac
AR024773A1 (es) 9-arilsulfonas e intermediarios.
CY1105706T1 (el) Υγρο σκευασμα που περιεχει ολιγοπεπτιδια και αιθεροποιημενη κυκλοδεξτρινη
CO4940463A1 (es) Macrolidas cristalinas
AR018706A1 (es) Uso de una composicion farmaceutica para tratamiento de infecciones virales
BR0016477A (pt) Canudo aperfeiçoado
NO20030931L (no) Cefalosporin-antibiotika og prodruger derav
DE50208396D1 (de) Taschenaschenbecher
HUP0300264A2 (hu) Linezolid intravénás oldatot tartalmazó tartály
ITMI20040235A1 (it) Preparazione farmaceutica per il cavo orale
ES2194640T3 (es) Solucion acuosa estable del derivado de la talidomida (em 12), para su administracion parenteral, y su procedimiento de preparacion.
AR045724A1 (es) Composicion farmaceutica orodispersable de un compuesto antitrombotico
JO2240B1 (en) Method for preparing dithylidene derivatives
ES2190267T3 (es) Recipiente de plastico que contiene formulaciones de farmacos estabilizadas.

Legal Events

Date Code Title Description
FC Refusal