YU96402A - Stabilni rastvori meloksikama, visoke koncentracije - Google Patents
Stabilni rastvori meloksikama, visoke koncentracijeInfo
- Publication number
- YU96402A YU96402A YU96402A YUP96402A YU96402A YU 96402 A YU96402 A YU 96402A YU 96402 A YU96402 A YU 96402A YU P96402 A YUP96402 A YU P96402A YU 96402 A YU96402 A YU 96402A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- highly concentrated
- concentrated stable
- meloxicam solutions
- meloxicam
- stable meloxicam
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Vodeni rastvor meloksikama koji ne sadrži ciklodekstrina, za primenu oralnim ili parenteralnim putem, koji sadrži farmakološki prihvtljivu so meloksikama sa organskom ili neorganskom bazom i jedan ili više pogodnih ekscipijenata, a sadržaj rastvorene soli meloksikama je veći od 10 mg/ml. Vreme upotrebljivosti formulacije, prema pronalasku, jeste do 24 meseca ili i duže.[Aqueous cyclodextrin-free solution of meloxicam for administration by oral or parenteral route, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients, the content of dissolved meloxicam salt being more than 10 mg/ml. The formulation according to the invention has a shelf-life of up to 24 months or more.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MEP-2008-398A ME00253B (me) | 2000-06-20 | 2001-06-19 | Stabilni rastvori meloksikama, visoke koncentracije |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10030345A DE10030345A1 (de) | 2000-06-20 | 2000-06-20 | Hochkonzentrierte stabile Meloxicamlösungen |
Publications (2)
Publication Number | Publication Date |
---|---|
YU96402A true YU96402A (sh) | 2006-01-16 |
RS50142B RS50142B (sr) | 2009-03-25 |
Family
ID=7646375
Country Status (32)
Country | Link |
---|---|
EP (1) | EP1299107B1 (sh) |
JP (2) | JP2003535902A (sh) |
KR (1) | KR100805651B1 (sh) |
CN (1) | CN1236774C (sh) |
AR (2) | AR028967A1 (sh) |
AT (1) | ATE297736T1 (sh) |
AU (2) | AU2001281852B2 (sh) |
BG (1) | BG65798B1 (sh) |
CA (1) | CA2414063C (sh) |
CZ (1) | CZ302717B6 (sh) |
DE (2) | DE10030345A1 (sh) |
EA (1) | EA005765B1 (sh) |
EC (1) | ECSP024371A (sh) |
EE (1) | EE04930B1 (sh) |
ES (1) | ES2244643T3 (sh) |
HK (1) | HK1057859A1 (sh) |
HR (1) | HRP20021011B1 (sh) |
HU (1) | HU229184B1 (sh) |
IL (2) | IL153114A0 (sh) |
ME (1) | ME00253B (sh) |
MX (1) | MXPA02012732A (sh) |
MY (1) | MY137729A (sh) |
NO (1) | NO330199B1 (sh) |
NZ (1) | NZ523583A (sh) |
PT (1) | PT1299107E (sh) |
RS (1) | RS50142B (sh) |
SK (1) | SK286938B6 (sh) |
TW (1) | TWI250018B (sh) |
UA (1) | UA73584C2 (sh) |
UY (1) | UY26781A1 (sh) |
WO (1) | WO2001097813A2 (sh) |
ZA (1) | ZA200209989B (sh) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020035107A1 (en) | 2000-06-20 | 2002-03-21 | Stefan Henke | Highly concentrated stable meloxicam solutions |
DE10030345A1 (de) * | 2000-06-20 | 2002-01-10 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen |
DE10161077A1 (de) | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
EP1348436A1 (en) * | 2002-03-30 | 2003-10-01 | Boehringer Ingelheim International GmbH | Meloxicam suppositories |
JP4707316B2 (ja) * | 2002-10-11 | 2011-06-22 | ロート製薬株式会社 | 水性液状組成物 |
DE10250081A1 (de) * | 2002-10-25 | 2004-05-13 | Boehringer Ingelheim Vetmedica Gmbh | Wasserlösliche Meloxicam Granulate |
US8992980B2 (en) | 2002-10-25 | 2015-03-31 | Boehringer Ingelheim Vetmedica Gmbh | Water-soluble meloxicam granules |
EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
DE102004025324A1 (de) * | 2004-05-19 | 2005-12-08 | Boehringer Ingelheim Vetmedica Gmbh | Flüssige Zubereitung für die Veterinärmedizin, Verfahren zu deren Herstellung und deren Verwendung |
DE102004030409A1 (de) * | 2004-06-23 | 2006-01-26 | Boehringer Ingelheim Vetmedica Gmbh | Neue Verwendung von Meloxicam in der Veterinärmedizin |
PL1824493T3 (pl) * | 2004-12-06 | 2009-01-30 | Janssen Pharmaceutica Nv | Zawiesina zawierająca meloksykam do podawania doustnego |
AU2006214166B2 (en) | 2005-02-17 | 2011-09-29 | Zoetis Belgium S.A. | Transmucosal administration of drug compositions for treating and preventing disorders in animals |
CN101584696A (zh) * | 2008-05-21 | 2009-11-25 | 上海艾力斯医药科技有限公司 | 包含喹唑啉衍生物的组合物及制备方法、用途 |
TR200809200A1 (tr) | 2008-12-01 | 2009-12-21 | Sanovel �La� Sanay� Ve T�Caret Anon�M ��Rket� | Meloksikam içeren farmasötik formülasyonlar |
US9101529B2 (en) | 2009-10-12 | 2015-08-11 | Boehringer Ingelheim Vetmedica Gmbh | Containers for compositions comprising meloxicam |
WO2011107150A1 (en) | 2010-03-03 | 2011-09-09 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats |
US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
KR101045052B1 (ko) * | 2011-01-18 | 2011-06-28 | 지수광 | 자세교정용 발받침대 |
CN102908310A (zh) * | 2012-11-02 | 2013-02-06 | 青岛康地恩药业股份有限公司 | 一种犬、猫用治疗类风湿性关节炎的美洛昔康注射液 |
CN104983686A (zh) * | 2015-07-13 | 2015-10-21 | 胡涵 | 畜禽用美洛昔康可溶性粉剂及其制备方法 |
CN105213402B (zh) * | 2015-09-30 | 2018-12-18 | 洛阳市兽药厂 | 一种畜禽复方恩诺沙星美洛昔康可溶性粉 |
EP3673897A4 (en) * | 2017-08-24 | 2021-05-05 | Jiangsu Hengrui Medicine Co., Ltd. | INJECTABLE PHARMACEUTICAL COMPOSITION WITH MELOXICAM AND METHOD FOR MANUFACTURING IT |
KR20190107481A (ko) * | 2018-03-12 | 2019-09-20 | 충북대학교 산학협력단 | 멜록시캄을 포함하는 구강붕해필름 제조방법 및 이에 의해 제조된 멜록시캄을 포함하는 구강붕해필름 |
US20210106591A1 (en) * | 2018-05-11 | 2021-04-15 | Nanjing Delova Biotech Co. Ltd. | Meloxicam composition, preparation and preparation method and use thereof |
CN112823787B (zh) * | 2019-11-21 | 2023-02-21 | 北京泰德制药股份有限公司 | 一种含有美洛昔康的注射液及其制备方法 |
WO2021224815A1 (en) * | 2020-05-06 | 2021-11-11 | Cadila Healthcare Limited | Stable aqueous parenteral solutions of nonsteroidal anti-inflammatory drug (nsaid) |
CN115068419A (zh) * | 2022-07-22 | 2022-09-20 | 潍坊恒邦兽药有限公司 | 兽用高浓度美洛昔康注射剂及其加工设备 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2756113A1 (de) * | 1977-12-16 | 1979-06-21 | Thomae Gmbh Dr K | Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
DE3217315C2 (de) * | 1982-05-08 | 1986-05-22 | Gödecke AG, 1000 Berlin | Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten |
HU195918B (en) * | 1984-03-14 | 1988-08-29 | Jerome Corbiere | Process for producing pharmaceutical compositions containing non-steroide antiflogistic active components |
DE3437232A1 (de) * | 1984-10-10 | 1986-04-17 | Mack Chem Pharm | Stabilisierte injektionsloesungen von piroxicam |
IT1207994B (it) * | 1986-01-03 | 1989-06-01 | Therapicon Srl | Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche. |
IT1216686B (it) * | 1988-04-01 | 1990-03-08 | Chiesi Farma Spa | Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione. |
JPH0418022A (ja) * | 1990-05-10 | 1992-01-22 | Fujikawa Kk | ピロキシカムの安定水溶液ならびにその製造法 |
HU205550B (en) * | 1990-11-27 | 1992-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pyroxycam solution of increased stability, free from effects damaging tussues |
US5599535A (en) * | 1995-06-07 | 1997-02-04 | Regents Of The University Of California | Methods for the cyto-protection of the trabecular meshwork |
US5674888A (en) * | 1995-06-07 | 1997-10-07 | University Of California | Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division |
ATA156496A (de) * | 1996-09-03 | 1997-10-15 | Nycomed Austria Gmbh | Pharmazeutische zusammensetzung |
EP0945134A1 (de) * | 1998-03-27 | 1999-09-29 | Boehringer Ingelheim Pharma KG | Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation |
JP4234907B2 (ja) * | 1998-05-15 | 2009-03-04 | わかもと製薬株式会社 | 抗炎症点眼剤 |
AU1548001A (en) * | 1999-11-24 | 2001-06-04 | Wakamoto Pharmaceutical Co., Ltd. | Ophthalmic aqueous preparation |
KR200182299Y1 (ko) * | 1999-12-08 | 2000-05-15 | 장지일 | 플로스 케이스를 포함하는 플로스 홀더 |
DE10030345A1 (de) * | 2000-06-20 | 2002-01-10 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen |
-
2000
- 2000-06-20 DE DE10030345A patent/DE10030345A1/de not_active Ceased
-
2001
- 2001-06-18 MY MYPI20012858A patent/MY137729A/en unknown
- 2001-06-18 TW TW090114711A patent/TWI250018B/zh not_active IP Right Cessation
- 2001-06-19 AU AU2001281852A patent/AU2001281852B2/en not_active Expired
- 2001-06-19 JP JP2002503297A patent/JP2003535902A/ja not_active Abandoned
- 2001-06-19 CN CNB018115608A patent/CN1236774C/zh not_active Expired - Lifetime
- 2001-06-19 ME MEP-2008-398A patent/ME00253B/me unknown
- 2001-06-19 UY UY26781A patent/UY26781A1/es not_active Application Discontinuation
- 2001-06-19 AT AT01960330T patent/ATE297736T1/de active
- 2001-06-19 ES ES01960330T patent/ES2244643T3/es not_active Expired - Lifetime
- 2001-06-19 EP EP01960330A patent/EP1299107B1/en not_active Expired - Lifetime
- 2001-06-19 AU AU8185201A patent/AU8185201A/xx active Pending
- 2001-06-19 HU HU0300854A patent/HU229184B1/hu unknown
- 2001-06-19 EE EEP200200701A patent/EE04930B1/xx unknown
- 2001-06-19 UA UA2003010501A patent/UA73584C2/uk unknown
- 2001-06-19 CZ CZ20024191A patent/CZ302717B6/cs not_active IP Right Cessation
- 2001-06-19 CA CA002414063A patent/CA2414063C/en not_active Expired - Lifetime
- 2001-06-19 RS YUP-964/02A patent/RS50142B/sr unknown
- 2001-06-19 SK SK1799-2002A patent/SK286938B6/sk not_active IP Right Cessation
- 2001-06-19 IL IL15311401A patent/IL153114A0/xx unknown
- 2001-06-19 KR KR1020027017309A patent/KR100805651B1/ko active IP Right Grant
- 2001-06-19 PT PT01960330T patent/PT1299107E/pt unknown
- 2001-06-19 WO PCT/EP2001/006904 patent/WO2001097813A2/en active Search and Examination
- 2001-06-19 NZ NZ523583A patent/NZ523583A/en not_active IP Right Cessation
- 2001-06-19 EA EA200201254A patent/EA005765B1/ru not_active IP Right Cessation
- 2001-06-19 MX MXPA02012732A patent/MXPA02012732A/es active IP Right Grant
- 2001-06-19 DE DE60111529T patent/DE60111529T2/de not_active Expired - Lifetime
- 2001-06-20 AR ARP010102932A patent/AR028967A1/es not_active Ceased/Invalidation/Refusal/Rejection/Nullification
-
2002
- 2002-11-27 IL IL153114A patent/IL153114A/en active IP Right Grant
- 2002-12-03 BG BG107347A patent/BG65798B1/bg active Active
- 2002-12-05 EC EC2002004371A patent/ECSP024371A/es unknown
- 2002-12-10 ZA ZA200209989A patent/ZA200209989B/en unknown
- 2002-12-18 HR HR20021011A patent/HRP20021011B1/xx not_active IP Right Cessation
- 2002-12-19 NO NO20026132A patent/NO330199B1/no not_active IP Right Cessation
-
2004
- 2004-01-21 HK HK04100469A patent/HK1057859A1/xx not_active IP Right Cessation
-
2010
- 2010-09-21 JP JP2010210791A patent/JP5330347B2/ja not_active Expired - Lifetime
-
2014
- 2014-08-12 AR ARP140103015A patent/AR100293A2/es not_active Application Discontinuation
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