EE04930B1 - K?rgkontsentreeritud stabiilsed meloksikaami lahused - Google Patents

K?rgkontsentreeritud stabiilsed meloksikaami lahused

Info

Publication number
EE04930B1
EE04930B1 EEP200200701A EEP200200701A EE04930B1 EE 04930 B1 EE04930 B1 EE 04930B1 EE P200200701 A EEP200200701 A EE P200200701A EE P200200701 A EEP200200701 A EE P200200701A EE 04930 B1 EE04930 B1 EE 04930B1
Authority
EE
Estonia
Prior art keywords
meloxicam
highly concentrated
stable solutions
concentrated stable
solutions
Prior art date
Application number
EEP200200701A
Other languages
English (en)
Inventor
Daneck Klaus
Andreas Folger Martin
Hassel Bernhard
Henke Stefan
Kroff Hans-J�rgen
Kruss Bernd
Prox Axel
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7646375&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE04930(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of EE200200701A publication Critical patent/EE200200701A/et
Publication of EE04930B1 publication Critical patent/EE04930B1/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EEP200200701A 2000-06-20 2001-06-19 K?rgkontsentreeritud stabiilsed meloksikaami lahused EE04930B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10030345A DE10030345A1 (de) 2000-06-20 2000-06-20 Hochkonzentrierte stabile Meloxicamlösungen
PCT/EP2001/006904 WO2001097813A2 (en) 2000-06-20 2001-06-19 Highly concentrated stable meloxicam solutions

Publications (2)

Publication Number Publication Date
EE200200701A EE200200701A (et) 2004-08-16
EE04930B1 true EE04930B1 (et) 2007-12-17

Family

ID=7646375

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200701A EE04930B1 (et) 2000-06-20 2001-06-19 K?rgkontsentreeritud stabiilsed meloksikaami lahused

Country Status (32)

Country Link
EP (1) EP1299107B1 (et)
JP (2) JP2003535902A (et)
KR (1) KR100805651B1 (et)
CN (1) CN1236774C (et)
AR (2) AR028967A1 (et)
AT (1) ATE297736T1 (et)
AU (2) AU2001281852B2 (et)
BG (1) BG65798B1 (et)
CA (1) CA2414063C (et)
CZ (1) CZ302717B6 (et)
DE (2) DE10030345A1 (et)
EA (1) EA005765B1 (et)
EC (1) ECSP024371A (et)
EE (1) EE04930B1 (et)
ES (1) ES2244643T3 (et)
HK (1) HK1057859A1 (et)
HR (1) HRP20021011B1 (et)
HU (1) HU229184B1 (et)
IL (2) IL153114A0 (et)
ME (1) ME00253B (et)
MX (1) MXPA02012732A (et)
MY (1) MY137729A (et)
NO (1) NO330199B1 (et)
NZ (1) NZ523583A (et)
PT (1) PT1299107E (et)
RS (1) RS50142B (et)
SK (1) SK286938B6 (et)
TW (1) TWI250018B (et)
UA (1) UA73584C2 (et)
UY (1) UY26781A1 (et)
WO (1) WO2001097813A2 (et)
ZA (1) ZA200209989B (et)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen
US20020035107A1 (en) 2000-06-20 2002-03-21 Stefan Henke Highly concentrated stable meloxicam solutions
DE10161077A1 (de) 2001-12-12 2003-06-18 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion
EP1348436A1 (en) * 2002-03-30 2003-10-01 Boehringer Ingelheim International GmbH Meloxicam suppositories
JP4707316B2 (ja) * 2002-10-11 2011-06-22 ロート製薬株式会社 水性液状組成物
US8992980B2 (en) 2002-10-25 2015-03-31 Boehringer Ingelheim Vetmedica Gmbh Water-soluble meloxicam granules
DE10250081A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Vetmedica Gmbh Wasserlösliche Meloxicam Granulate
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
DE102004025324A1 (de) * 2004-05-19 2005-12-08 Boehringer Ingelheim Vetmedica Gmbh Flüssige Zubereitung für die Veterinärmedizin, Verfahren zu deren Herstellung und deren Verwendung
DE102004030409A1 (de) * 2004-06-23 2006-01-26 Boehringer Ingelheim Vetmedica Gmbh Neue Verwendung von Meloxicam in der Veterinärmedizin
PL1824493T3 (pl) 2004-12-06 2009-01-30 Janssen Pharmaceutica Nv Zawiesina zawierająca meloksykam do podawania doustnego
JP5577021B2 (ja) 2005-02-17 2014-08-20 アボット・ラボラトリーズ 動物における障害を治療および予防するための薬剤組成物の経粘膜投与
CN101584696A (zh) * 2008-05-21 2009-11-25 上海艾力斯医药科技有限公司 包含喹唑啉衍生物的组合物及制备方法、用途
TR200809200A1 (tr) 2008-12-01 2009-12-21 Sanovel �La� Sanay� Ve T�Caret Anon�M ��Rket� Meloksikam içeren farmasötik formülasyonlar
IN2012DN03157A (et) 2009-10-12 2015-09-18 Boehringer Ingelheim Vetmed
AU2010347598B2 (en) 2010-03-03 2014-11-27 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the long-term treatment of musculoskeletal disorders in cats
US9795568B2 (en) 2010-05-05 2017-10-24 Boehringer Ingelheim Vetmedica Gmbh Low concentration meloxicam tablets
KR101045052B1 (ko) * 2011-01-18 2011-06-28 지수광 자세교정용 발받침대
CN102908310A (zh) * 2012-11-02 2013-02-06 青岛康地恩药业股份有限公司 一种犬、猫用治疗类风湿性关节炎的美洛昔康注射液
CN104983686A (zh) * 2015-07-13 2015-10-21 胡涵 畜禽用美洛昔康可溶性粉剂及其制备方法
CN105213402B (zh) * 2015-09-30 2018-12-18 洛阳市兽药厂 一种畜禽复方恩诺沙星美洛昔康可溶性粉
TW201912148A (zh) * 2017-08-24 2019-04-01 大陸商江蘇恆瑞醫藥股份有限公司 一種包含美洛昔康的可注射的醫藥組成物及其製備方法
KR20190107481A (ko) * 2018-03-12 2019-09-20 충북대학교 산학협력단 멜록시캄을 포함하는 구강붕해필름 제조방법 및 이에 의해 제조된 멜록시캄을 포함하는 구강붕해필름
CN116327959A (zh) * 2018-05-11 2023-06-27 南京清普生物科技有限公司 一种美洛昔康组合物、制剂及其制备方法与应用
CN112823786A (zh) * 2019-11-21 2021-05-21 北京泰德制药股份有限公司 一种含有美洛昔康的药物组合物及应用
WO2021224815A1 (en) * 2020-05-06 2021-11-11 Cadila Healthcare Limited Stable aqueous parenteral solutions of nonsteroidal anti-inflammatory drug (nsaid)
CN115068419A (zh) * 2022-07-22 2022-09-20 潍坊恒邦兽药有限公司 兽用高浓度美洛昔康注射剂及其加工设备

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DE2756113A1 (de) * 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE3217315C2 (de) * 1982-05-08 1986-05-22 Gödecke AG, 1000 Berlin Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten
HU195918B (en) * 1984-03-14 1988-08-29 Jerome Corbiere Process for producing pharmaceutical compositions containing non-steroide antiflogistic active components
DE3437232A1 (de) * 1984-10-10 1986-04-17 Mack Chem Pharm Stabilisierte injektionsloesungen von piroxicam
IT1207994B (it) * 1986-01-03 1989-06-01 Therapicon Srl Sali idrosulubili di composti adattivita' antiinfiammatoria ed analgesica, loro preparazione ed utilizzo in composizioni farmaceutiche.
IT1216686B (it) * 1988-04-01 1990-03-08 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione.
JPH0418022A (ja) * 1990-05-10 1992-01-22 Fujikawa Kk ピロキシカムの安定水溶液ならびにその製造法
HU205550B (en) * 1990-11-27 1992-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pyroxycam solution of increased stability, free from effects damaging tussues
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
ATA156496A (de) * 1996-09-03 1997-10-15 Nycomed Austria Gmbh Pharmazeutische zusammensetzung
EP0945134A1 (de) * 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation
EP1082966A4 (en) * 1998-05-15 2004-07-21 Wakamoto Pharma Co Ltd ANTI-INFLAMMATORY EYE DROPS
AU1548001A (en) * 1999-11-24 2001-06-04 Wakamoto Pharmaceutical Co., Ltd. Ophthalmic aqueous preparation
KR200182299Y1 (ko) * 1999-12-08 2000-05-15 장지일 플로스 케이스를 포함하는 플로스 홀더
DE10030345A1 (de) * 2000-06-20 2002-01-10 Boehringer Ingelheim Vetmed Hochkonzentrierte stabile Meloxicamlösungen

Also Published As

Publication number Publication date
CA2414063A1 (en) 2001-12-27
KR20030013447A (ko) 2003-02-14
ECSP024371A (es) 2003-02-06
DE60111529T2 (de) 2005-12-15
NZ523583A (en) 2004-09-24
AU8185201A (en) 2002-01-02
JP2003535902A (ja) 2003-12-02
EE200200701A (et) 2004-08-16
RS50142B (sr) 2009-03-25
JP5330347B2 (ja) 2013-10-30
WO2001097813A3 (en) 2002-05-10
EA200201254A1 (ru) 2003-06-26
SK17992002A3 (sk) 2003-04-01
YU96402A (sh) 2006-01-16
NO20026132D0 (no) 2002-12-19
HK1057859A1 (en) 2004-04-23
CZ302717B6 (cs) 2011-09-21
EA005765B1 (ru) 2005-06-30
AR028967A1 (es) 2003-05-28
HRP20021011B1 (en) 2006-02-28
NO20026132L (no) 2003-02-11
BG65798B1 (bg) 2009-12-31
ES2244643T3 (es) 2005-12-16
CZ20024191A3 (cs) 2003-04-16
MEP39808A (en) 2011-02-10
AU2001281852B2 (en) 2006-04-13
WO2001097813A2 (en) 2001-12-27
KR100805651B1 (ko) 2008-02-26
UY26781A1 (es) 2002-01-31
UA73584C2 (en) 2005-08-15
HU229184B1 (en) 2013-09-30
DE10030345A1 (de) 2002-01-10
IL153114A (en) 2011-07-31
PL359553A1 (en) 2004-08-23
CN1437472A (zh) 2003-08-20
ATE297736T1 (de) 2005-07-15
ME00253B (me) 2011-05-10
EP1299107A2 (en) 2003-04-09
AR100293A2 (es) 2016-09-28
NO330199B1 (no) 2011-03-07
ZA200209989B (en) 2003-10-08
HRP20021011A2 (en) 2005-02-28
DE60111529D1 (de) 2005-07-21
PT1299107E (pt) 2005-08-31
HUP0300854A2 (hu) 2003-08-28
IL153114A0 (en) 2003-06-24
TWI250018B (en) 2006-03-01
JP2010280726A (ja) 2010-12-16
BG107347A (en) 2003-09-30
MXPA02012732A (es) 2004-09-10
CA2414063C (en) 2008-06-17
SK286938B6 (sk) 2009-07-06
EP1299107B1 (en) 2005-06-15
MY137729A (en) 2009-03-31
CN1236774C (zh) 2006-01-18

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Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231