AR072809A1 - Compuesto de (3- piridinilcarbonil)-4-(fenilsulfonilpiperazina ), su uso para la elaboracion de unmedicamento para el tratamiento del dolor y composicion farmaceutica que lo comprende - Google Patents
Compuesto de (3- piridinilcarbonil)-4-(fenilsulfonilpiperazina ), su uso para la elaboracion de unmedicamento para el tratamiento del dolor y composicion farmaceutica que lo comprendeInfo
- Publication number
- AR072809A1 AR072809A1 ARP090102692A ARP090102692A AR072809A1 AR 072809 A1 AR072809 A1 AR 072809A1 AR P090102692 A ARP090102692 A AR P090102692A AR P090102692 A ARP090102692 A AR P090102692A AR 072809 A1 AR072809 A1 AR 072809A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydrogen
- cyano
- halogen
- alkyl
- halogenoalkoxy
- Prior art date
Links
- NANQJUFFKXWVJR-UHFFFAOYSA-N 1-(benzenesulfonyl)piperazine Chemical compound C=1C=CC=CC=1S(=O)(=O)N1CCNCC1 NANQJUFFKXWVJR-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000002131 composite material Substances 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 4
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 3
- 125000001188 haloalkyl group Chemical group 0.000 abstract 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 125000006661 (C4-C6) heterocyclic group Chemical group 0.000 abstract 1
- -1 3-pyridinylcarbonyl Chemical group 0.000 abstract 1
- 101000935123 Homo sapiens Voltage-dependent N-type calcium channel subunit alpha-1B Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 102100025342 Voltage-dependent N-type calcium channel subunit alpha-1B Human genes 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0813142.7A GB0813142D0 (en) | 2008-07-17 | 2008-07-17 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR072809A1 true AR072809A1 (es) | 2010-09-22 |
Family
ID=39737239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090102692A AR072809A1 (es) | 2008-07-17 | 2009-07-15 | Compuesto de (3- piridinilcarbonil)-4-(fenilsulfonilpiperazina ), su uso para la elaboracion de unmedicamento para el tratamiento del dolor y composicion farmaceutica que lo comprende |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US8288388B2 (enExample) |
| EP (2) | EP2300432B1 (enExample) |
| JP (2) | JP5543966B2 (enExample) |
| KR (1) | KR101599087B1 (enExample) |
| CN (1) | CN102099337B (enExample) |
| AR (1) | AR072809A1 (enExample) |
| AU (1) | AU2009272762B2 (enExample) |
| BR (1) | BRPI0916622A2 (enExample) |
| CA (1) | CA2730471C (enExample) |
| EA (1) | EA018621B1 (enExample) |
| ES (2) | ES2396962T3 (enExample) |
| GB (1) | GB0813142D0 (enExample) |
| IL (1) | IL210446A (enExample) |
| MX (1) | MX2011000600A (enExample) |
| PL (1) | PL2300432T3 (enExample) |
| TW (1) | TW201016677A (enExample) |
| UY (1) | UY31990A (enExample) |
| WO (2) | WO2010007072A1 (enExample) |
| ZA (1) | ZA201100014B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0813142D0 (en) * | 2008-07-17 | 2008-08-27 | Glaxo Group Ltd | Novel compounds |
| GB201000685D0 (en) | 2010-01-15 | 2010-03-03 | Glaxo Group Ltd | Novel compounds |
| JP6058556B2 (ja) * | 2011-01-19 | 2017-01-11 | クオンベルゲンセ プハルマセウトイカルス リミテッド | ＣａＶ２．２カルシウムチャンネルブロッカーとしてのピペラジン誘導体 |
| MX345873B (es) | 2011-06-27 | 2017-02-21 | Newron Pharm Spa | Derivados de arilalquilaminocarboxamida fluorados. |
| WO2015158426A1 (en) * | 2014-04-14 | 2015-10-22 | Grünenthal GmbH | Aryl substituted heterocyclyl sulfones |
| AR100073A1 (es) * | 2014-04-14 | 2016-09-07 | Gruenenthal Gmbh | Sulfonas heterocíclicas sustituidas con heteroarilos |
| GB201516183D0 (en) * | 2015-09-14 | 2015-10-28 | Calchan Ltd | Novel pharmaceutical composition |
| TW201726128A (zh) | 2015-10-08 | 2017-08-01 | 歌林達有限公司 | 經吡唑基取代之四氫哌喃基碸 |
| TW201718557A (zh) | 2015-10-08 | 2017-06-01 | 歌林達有限公司 | 經吡唑基取代之四氫吡喃基碸 |
| SG10202111885PA (en) * | 2017-04-26 | 2021-12-30 | Cavion Inc | Methods for improving memory and cognition and for treating memory and cognitive disorders |
| CN118085389B (zh) * | 2024-03-11 | 2024-11-05 | 伟建实业(苏州)有限公司 | 一种环保型抗菌海绵及其制备方法 |
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| US5474995A (en) | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
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| GB0813142D0 (en) * | 2008-07-17 | 2008-08-27 | Glaxo Group Ltd | Novel compounds |
-
2008
- 2008-07-17 GB GBGB0813142.7A patent/GB0813142D0/en not_active Ceased
-
2009
- 2009-07-15 UY UY0001031990A patent/UY31990A/es unknown
- 2009-07-15 AR ARP090102692A patent/AR072809A1/es unknown
- 2009-07-15 WO PCT/EP2009/059011 patent/WO2010007072A1/en not_active Ceased
- 2009-07-15 EA EA201170209A patent/EA018621B1/ru not_active IP Right Cessation
- 2009-07-15 ES ES09780587T patent/ES2396962T3/es active Active
- 2009-07-15 US US12/503,125 patent/US8288388B2/en not_active Expired - Fee Related
- 2009-07-15 CA CA2730471A patent/CA2730471C/en not_active Expired - Fee Related
- 2009-07-15 PL PL09780587T patent/PL2300432T3/pl unknown
- 2009-07-15 MX MX2011000600A patent/MX2011000600A/es active IP Right Grant
- 2009-07-15 JP JP2011517911A patent/JP5543966B2/ja not_active Expired - Fee Related
- 2009-07-15 WO PCT/EP2009/059012 patent/WO2010007073A1/en not_active Ceased
- 2009-07-15 TW TW098123842A patent/TW201016677A/zh unknown
- 2009-07-15 AU AU2009272762A patent/AU2009272762B2/en not_active Ceased
- 2009-07-15 US US13/054,265 patent/US8530478B2/en not_active Expired - Fee Related
- 2009-07-15 KR KR1020117001109A patent/KR101599087B1/ko not_active Expired - Fee Related
- 2009-07-15 JP JP2011517910A patent/JP5688850B2/ja not_active Expired - Fee Related
- 2009-07-15 EP EP09780587A patent/EP2300432B1/en not_active Not-in-force
- 2009-07-15 CN CN200980127788XA patent/CN102099337B/zh not_active Expired - Fee Related
- 2009-07-15 EP EP09780586A patent/EP2346828B1/en not_active Not-in-force
- 2009-07-15 BR BRPI0916622-0A patent/BRPI0916622A2/pt not_active IP Right Cessation
- 2009-07-15 ES ES09780586T patent/ES2396960T3/es active Active
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2011
- 2011-01-03 ZA ZA2011/00014A patent/ZA201100014B/en unknown
- 2011-01-03 IL IL210446A patent/IL210446A/en not_active IP Right Cessation
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2012
- 2012-08-07 US US13/568,211 patent/US8536183B2/en not_active Expired - Fee Related
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