AR071120A1 - Derivados de diosmetina, su procedimiento de preparacion, las composiciones farmaceuticas que los contienen y su uso en el tratamiento de las enfermedades venosas cronicas. - Google Patents
Derivados de diosmetina, su procedimiento de preparacion, las composiciones farmaceuticas que los contienen y su uso en el tratamiento de las enfermedades venosas cronicas.Info
- Publication number
- AR071120A1 AR071120A1 ARP090101138A ARP090101138A AR071120A1 AR 071120 A1 AR071120 A1 AR 071120A1 AR P090101138 A ARP090101138 A AR P090101138A AR P090101138 A ARP090101138 A AR P090101138A AR 071120 A1 AR071120 A1 AR 071120A1
- Authority
- AR
- Argentina
- Prior art keywords
- diosmetine
- derivatives
- contain
- treatment
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/07—Benzo[b]pyran-4-ones
Abstract
Compuestos de formula (1) en la que R1, R2 y R3, idénticos o diferentes, representan cada uno un átomo de H o el grupo de formula (2). Medicamentos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0801779A FR2929276B1 (fr) | 2008-04-01 | 2008-04-01 | Nouveaux derives de diosmetine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR071120A1 true AR071120A1 (es) | 2010-05-26 |
Family
ID=39809617
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090101138A AR071120A1 (es) | 2008-04-01 | 2009-03-31 | Derivados de diosmetina, su procedimiento de preparacion, las composiciones farmaceuticas que los contienen y su uso en el tratamiento de las enfermedades venosas cronicas. |
| ARP170102686A AR109739A2 (es) | 2008-04-01 | 2017-09-28 | Composiciones farmacéuticas que comprenden derivados de diosmetina |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP170102686A AR109739A2 (es) | 2008-04-01 | 2017-09-28 | Composiciones farmacéuticas que comprenden derivados de diosmetina |
Country Status (48)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2002835A1 (en) | 2007-06-04 | 2008-12-17 | GenKyo Tex | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2166010A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2166009A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as nadph oxidase inhibitors |
| EP2165707A1 (en) | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolo pyridine derivatives as NADPH oxidase inhibitors |
| EP2305679A1 (en) | 2009-09-28 | 2011-04-06 | GenKyoTex SA | Pyrazoline dione derivatives as nadph oxidase inhibitors |
| FR3002543A1 (fr) * | 2013-02-28 | 2014-08-29 | Servier Lab | Procede de synthese enzymatique de flavonoides, et application a la synthese de derives de diosmetine |
| CN106031723A (zh) * | 2015-09-29 | 2016-10-19 | 西南大学 | 香叶木素的抗炎活性及其制剂应用 |
| CN106822087A (zh) * | 2017-01-12 | 2017-06-13 | 西南大学 | 香叶木素在制备治疗ⅱ型糖尿病的药物中的应用 |
| SG11201910172VA (en) * | 2017-05-04 | 2019-11-28 | Glenmark Pharmaceuticals Sa | Substituted bicyclic heterocyclic compounds as nadph oxidase inhibitors |
| ES2957742T3 (es) * | 2017-07-19 | 2024-01-24 | Primus Pharmaceuticals Inc | Métodos de tratamiento de los transtornos microvasculares autoinmunes |
| CN109280067B (zh) * | 2017-07-21 | 2022-07-05 | 南京正大天晴制药有限公司 | 香叶木苷衍生物、其制备方法以及医药用途 |
| CN111885914B (zh) * | 2017-10-27 | 2022-05-13 | 投资健康有限责任公司 | 使用芴衍生物制造扩增的造血干细胞的组合物和方法 |
| CN109394753B (zh) * | 2018-12-24 | 2020-10-02 | 武汉轻工大学 | 香叶木素在制备预防和/或治疗高尿酸血症肾病的药物中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2701261B1 (fr) * | 1993-02-05 | 1995-03-31 | Adir | Nouveaux composés glucuronides de la diosmétine, leur procédé de préparation et les compositions pharmaceutiques les renfermant. |
| FR2726273B1 (fr) * | 1994-10-26 | 1996-12-06 | Adir | Nouveaux derives de la diosmetine, leur procede de preparation et les compositions pharmaceutiques les contenant |
| FR2748025B1 (fr) * | 1996-04-25 | 1998-10-30 | Adir | Nouveaux acides et esters de la diosmetine, et les compositions pharmaceutiques les contenant |
| EE200000504A (et) * | 1998-03-12 | 2002-02-15 | Teijin Limited | Bensofurüül-a-pürooni derivaadid, farmatseutilinekompositsioon, lipiidide ainevahetuse kiirendaja,triglütseriidi biosünteesi inhibiitor, vere triglütseriiditaset alandav toimeaine, vere HDL taset tõstev toimeaine, arterioskleroosi profülaktiline to |
| GB9920912D0 (en) * | 1999-09-03 | 1999-11-10 | Indena Spa | Novel derivatives of flavones,xanthones and coumarins |
| FR2882654B1 (fr) * | 2005-03-01 | 2007-04-27 | Servier Lab | Utilisation de derives de la diosmetine pour le traitement et la prevention des pathologies thrombotiques |
-
2008
- 2008-04-01 FR FR0801779A patent/FR2929276B1/fr not_active Expired - Fee Related
-
2009
- 2009-03-12 SG SG200901706-2A patent/SG155849A1/en unknown
- 2009-03-12 PE PE2009000365A patent/PE20091692A1/es active IP Right Grant
- 2009-03-13 MY MYPI20091038A patent/MY144726A/en unknown
- 2009-03-13 UY UY31712A patent/UY31712A1/es active IP Right Grant
- 2009-03-17 JO JO2009107A patent/JO2673B1/en active
- 2009-03-17 CR CR10665A patent/CR10665A/es unknown
- 2009-03-17 AU AU2009201068A patent/AU2009201068B2/en active Active
- 2009-03-17 IL IL197638A patent/IL197638A/en active IP Right Grant
- 2009-03-18 GT GT200900062A patent/GT200900062A/es unknown
- 2009-03-19 ZA ZA2009/01947A patent/ZA200901947B/en unknown
- 2009-03-20 CO CO09029385A patent/CO6150038A1/es active IP Right Grant
- 2009-03-23 AP AP2009004810A patent/AP3024A/xx active
- 2009-03-25 GE GEAP200911185A patent/GEP20115342B/en unknown
- 2009-03-26 CU CU20090048A patent/CU23761B7/es active IP Right Grant
- 2009-03-27 CN CN2009101324295A patent/CN101550124B/zh active Active
- 2009-03-27 CL CL2009000757A patent/CL2009000757A1/es unknown
- 2009-03-27 UA UAA200902916A patent/UA98623C2/ru unknown
- 2009-03-30 MA MA31742A patent/MA31413B1/fr unknown
- 2009-03-30 HN HN2009000566A patent/HN2009000566A/es unknown
- 2009-03-30 SA SA109300201A patent/SA109300201B1/ar unknown
- 2009-03-30 EC EC2009009216A patent/ECSP099216A/es unknown
- 2009-03-30 NZ NZ575902A patent/NZ575902A/en unknown
- 2009-03-30 MX MX2009003383A patent/MX2009003383A/es active IP Right Grant
- 2009-03-30 US US12/383,888 patent/US8138223B2/en active Active
- 2009-03-30 SV SV2009003199A patent/SV2009003199A/es unknown
- 2009-03-31 BR BRPI0900983A patent/BRPI0900983B8/pt active IP Right Grant
- 2009-03-31 PL PL09290237T patent/PL2107055T3/pl unknown
- 2009-03-31 SI SI200930019T patent/SI2107055T1/sl unknown
- 2009-03-31 NI NI200900042A patent/NI200900042A/es unknown
- 2009-03-31 PT PT09290237T patent/PT2107055E/pt unknown
- 2009-03-31 EP EP09290237A patent/EP2107055B1/fr active Active
- 2009-03-31 CA CA2659947A patent/CA2659947C/fr active Active
- 2009-03-31 ES ES09290237T patent/ES2363196T3/es active Active
- 2009-03-31 AT AT09290237T patent/ATE502024T1/de active
- 2009-03-31 JP JP2009084080A patent/JP5047211B2/ja active Active
- 2009-03-31 DE DE602009000873T patent/DE602009000873D1/de active Active
- 2009-03-31 WO PCT/FR2009/000371 patent/WO2009133269A1/fr active Application Filing
- 2009-03-31 ME MEP-109/09A patent/MEP10909A/xx unknown
- 2009-03-31 RS RS20110142A patent/RS51661B/en unknown
- 2009-03-31 TW TW098110698A patent/TWI385178B/zh not_active IP Right Cessation
- 2009-03-31 DK DK09290237.8T patent/DK2107055T3/da active
- 2009-03-31 EA EA200900397A patent/EA015424B1/ru unknown
- 2009-03-31 AR ARP090101138A patent/AR071120A1/es active IP Right Grant
-
2010
- 2010-03-29 HK HK10103244.6A patent/HK1136291A1/xx not_active IP Right Cessation
-
2011
- 2011-03-22 CY CY20111100344T patent/CY1111367T1/el unknown
- 2011-05-16 HR HR20110361T patent/HRP20110361T1/hr unknown
-
2012
- 2012-02-14 US US13/372,811 patent/US8404742B2/en active Active
- 2012-04-16 KR KR1020120039373A patent/KR20120049855A/ko not_active Application Discontinuation
-
2017
- 2017-09-28 AR ARP170102686A patent/AR109739A2/es not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR071120A1 (es) | Derivados de diosmetina, su procedimiento de preparacion, las composiciones farmaceuticas que los contienen y su uso en el tratamiento de las enfermedades venosas cronicas. | |
| UY31673A1 (es) | "derivados heterocíclicos de urea y métodos de uso de los mismos-211" | |
| ECSP109903A (es) | Derivados de pirazinona y su uso en el tratamiento de enfermedades pulmonares | |
| CL2011000589A1 (es) | Compuestos derivados de pirrolidin-2-carboxamida, inhibidores de la interaccion p53-mdm2; composicion farmaceutica que los comprende; y su uso en la preparacion de medicamentos utiles para el tratamiento del cancer. | |
| CL2008003096A1 (es) | Compuestos derivados de piperidino-dihidrotienopirimidinas; inhibidores pde4; composicion farmaceutica que los comprende; y uso en el tratamiento de trastornos o enfermedades de las vias respiratorias o gastrointestinales, como tambien enfermedades inflamatorias de las articulaciones u ojos, entre otras. | |
| UY32158A (es) | Derivados heterociclicos y metodos de uso de los mismos | |
| AR047928A1 (es) | Derivados de tetrahidropiridoindol | |
| UY30759A1 (es) | Compuestos quimicos | |
| ECSP12011867A (es) | Derivados bencimidazol-imidazol | |
| ECSP088329A (es) | Nuevos diazaespiroalcanos y su uso para el tratamiento de enfermedades mediadas por ccr8 | |
| ECSP10010548A (es) | Composiciones y metodos de preparacion y uso de las mismas | |
| PA8720801A1 (es) | Nuevas combinaciones terapeuticas para el tratamiento de la depresion | |
| UY31314A1 (es) | Amidas heterociclicas y sus métodos de uso-976 | |
| UY30846A1 (es) | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos | |
| UY30183A1 (es) | Derivados de quinolina | |
| BRPI0606112A2 (pt) | 3 - heteroaril - 3 - hidróxi - 2 - amino - propil aminas e compostos relacionados, bem como uso dos mesmos e composição farmacêutica | |
| UY29732A1 (es) | Derivados de benzotiazolonas, procesos de preparación, composiciones y combinaciones que los contienen y aplicaciones | |
| UY32315A (es) | Compuestos de piperidina y usos de los mismo-596 | |
| GT200600161A (es) | Nuevas combinaciones terapeuticas para el tratamiento o la prevencion de los trastornos psicoticos | |
| CR20140144A (es) | Derivados de estra-1,3,5 (10), 16-tetraen-3-carboxamida, procedimientos para su preparación, preparados farmacéuticos que los contienen, así como su uso para la preparación de medicamentos | |
| CL2015002346A1 (es) | Estra-1,3,5(10),16-tetraeno-3-carboxamidas para la inhibicion de la 17b-hidroxiesteroide deshidrogenasa (akr1 c3) | |
| UY31864A (es) | Derivados de urea hetericíclica y métodos de uso de los mismos-332 | |
| CR11584A (es) | Derivados de oxindol sustituidos y uso de los mismos para el tratamiento de enfermedades dependientes de la vasopresina | |
| UY30424A1 (es) | Derivados de quinolina, su preparacion, su uso y medicamentos que comprenden los mismos. | |
| CL2019002480A1 (es) | Derivados de pirazol como inhibidores de bromodominio. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |