AR046276A1 - Derivados de amida como ligandos de canales ionicos y composiciones farmaceuticas y metodos que los utilizan. - Google Patents
Derivados de amida como ligandos de canales ionicos y composiciones farmaceuticas y metodos que los utilizan.Info
- Publication number
- AR046276A1 AR046276A1 ARP040103646A ARP040103646A AR046276A1 AR 046276 A1 AR046276 A1 AR 046276A1 AR P040103646 A ARP040103646 A AR P040103646A AR P040103646 A ARP040103646 A AR P040103646A AR 046276 A1 AR046276 A1 AR 046276A1
- Authority
- AR
- Argentina
- Prior art keywords
- substituted
- alkyl
- atom
- unsubstituted
- heteroalkyl
- Prior art date
Links
- 102000004310 Ion Channels Human genes 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 5
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 125000004429 atom Chemical group 0.000 abstract 4
- 125000004404 heteroalkyl group Chemical group 0.000 abstract 4
- 125000001072 heteroaryl group Chemical group 0.000 abstract 4
- -1 sulfuric acid ester Chemical class 0.000 abstract 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 3
- 125000001931 aliphatic group Chemical group 0.000 abstract 3
- 125000004475 heteroaralkyl group Chemical group 0.000 abstract 3
- 125000003282 alkyl amino group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- 125000004391 aryl sulfonyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000005553 heteroaryloxy group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001476 phosphono group Chemical group [H]OP(*)(=O)O[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
- 150000003457 sulfones Chemical class 0.000 abstract 1
- 150000003462 sulfoxides Chemical class 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Classifications
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- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
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| BRPI0606365A2 (pt) * | 2005-02-28 | 2017-06-27 | Renovis Inc | composto ou um sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo e estereoisômeros e tautômeros do mesmo, composição farmacêutica, métodos para prevenir, tratar, melhorar ou controlar uma doença ou condição e para preparar um composto, uso de um composto ou um sal, solvato ou composição farmaceuticamente aceitável do mesmo, método de tratamento de um mamífero, e, combinação |
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-
2004
- 2004-10-07 US US10/961,483 patent/US7432281B2/en not_active Expired - Fee Related
- 2004-10-07 WO PCT/US2004/033163 patent/WO2005046683A1/en not_active Ceased
- 2004-10-07 CA CA002541949A patent/CA2541949A1/en not_active Abandoned
- 2004-10-07 BR BRPI0415179-8A patent/BRPI0415179A/pt not_active IP Right Cessation
- 2004-10-07 AR ARP040103646A patent/AR046276A1/es unknown
- 2004-10-07 MX MXPA06003951A patent/MXPA06003951A/es not_active Application Discontinuation
- 2004-10-07 TW TW093130317A patent/TW200526631A/zh unknown
- 2004-10-07 EP EP04794499A patent/EP1680109A4/en not_active Withdrawn
- 2004-10-07 JP JP2006534356A patent/JP4667384B2/ja not_active Expired - Fee Related
-
2008
- 2008-07-18 US US12/218,973 patent/US20080312237A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| TW200526631A (en) | 2005-08-16 |
| US7432281B2 (en) | 2008-10-07 |
| CA2541949A1 (en) | 2005-05-26 |
| US20050222200A1 (en) | 2005-10-06 |
| EP1680109A1 (en) | 2006-07-19 |
| EP1680109A4 (en) | 2009-05-06 |
| US20080312237A1 (en) | 2008-12-18 |
| MXPA06003951A (es) | 2006-06-27 |
| JP2007509043A (ja) | 2007-04-12 |
| BRPI0415179A (pt) | 2006-11-28 |
| JP4667384B2 (ja) | 2011-04-13 |
| WO2005046683A1 (en) | 2005-05-26 |
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